Or5ak25 (olfactory receptor family 5 subfamily AK member 25) - Rat Genome Database

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Gene: Or5ak25 (olfactory receptor family 5 subfamily AK member 25) Mus musculus
Analyze
No known orthologs.
Symbol: Or5ak25
Name: olfactory receptor family 5 subfamily AK member 25
RGD ID: 1550990
MGI Page MGI
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and sensory perception of smell. Predicted to be located in membrane. Orthologous to human OR5AK2 (olfactory receptor family 5 subfamily AK member 2) and OR5AK3P (olfactory receptor family 5 subfamily AK member 3 pseudogene).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: GA_x6K02T2Q125-46915844-46914897; MOR203; MOR203-3; olfactory receptor 995; olfactory receptor MOR203-3; Olfr995
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Pseudogenes: Or5aj1-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39285,268,553 - 85,269,500 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl285,267,872 - 85,273,983 (-)EnsemblGRCm39 Ensembl
GRCm38285,438,209 - 85,439,156 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl285,437,528 - 85,443,639 (-)EnsemblGRCm38mm10GRCm38
MGSCv37285,278,366 - 85,279,313 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36285,239,048 - 85,239,995 (-)NCBIMGSCv36mm8
Celera287,019,603 - 87,020,550 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11802173   PMID:11875048   PMID:12477932   PMID:14611657   PMID:21873635   PMID:32295537  


Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:55
Interacting mature miRNAs:57
Transcripts:ENSMUST00000099924
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13464141Hbbcq3_mhemoglobin concentration QTL 3 (mouse)25244801986448136Mouse
39128209Lwq14_mliver weight QTL 14 (mouse)220897778118894840Mouse
1558738W6q1_mweight 6 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
1300761Lgth1_mbody length 1 (mouse)Not determined25170327685703425Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
4141236Hbnr5_mHeligmosomoides bakeri nematode resistance 5 (mouse)Not determined31214567105143570Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
1301405Etohr_methanol response acute (mouse)Not determined26300595497006113Mouse
1301660Iba1_minduction of brown adipocytes 1 (mouse)Not determined267647887101648142Mouse
1558915W3q1_mweight 3 weeks QTL 1 (mouse)Not determined220897778118894840Mouse
1301703Bomd3_mbone mineral density 3 (mouse)Not determined26300595497006113Mouse
1301769Orgwq2_morgan weight QTL 2 (mouse)Not determined2388712693421651Mouse
1357454Kidq1_mkidney weight QTL 1 (mouse)Not determined220897778118894840Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1357577Trmq3_mT cell ratio modifier QTL 3 (mouse)Not determined260520612119355518Mouse
1558966W10q9_mweight 10 weeks QTL 9 (mouse)Not determined220897778118894840Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
4141406Alpq2_malcohol preference QTL 2 (mouse)Not determined25752411791524288Mouse
13463471Hctq6_mhematocrit QTL 6 (mouse)25244801986448136Mouse
1301873Hsl1_mhyperoxia susceptibility locus 1 (mouse)Not determined26357015497570301Mouse
1558901Skmw8_mskeletal muscle weight 8 (mouse)Not determined284008488118008593Mouse
1558899Egq1_mearly growth QTL 1 (mouse)Not determined220897778118894840Mouse
1357681Hrtq1_mheart weight QTL 1 (mouse)Not determined220897778118894840Mouse
1300662Etohila_methanol induced locomotor activity (mouse)Not determined26300595497006113Mouse
1301109Dntcs2_mdental caries susceptibility 2 (mouse)Not determined240885493114910165Mouse
4141657Mohg1_mmodifier of hg 1 (mouse)Not determined276678758103095823Mouse
1357436Splq1_mspleen weight QTL 1 (mouse)Not determined220897778118894840Mouse
10053681Lith24_mlithogenic gene 24 (mouse)Not determined26300595497006113Mouse
1301882Etohc2_methanol consumption 2 (mouse)Not determined268724269102724407Mouse
1301048Actre2_mactivity response to ethanol 2 (mouse)Not determined26300595497006113Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1357881Estoq1_membryo survival total QTL 1 (mouse)Not determined220897778118894840Mouse
1301374Cplaq7_mcircadian period of locomotor activity 7 (mouse)Not determined276421483110421651Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
1301948Elsgp3_melevated serum gp70 3 (mouse)Not determined268724269102724407Mouse
10043894Bw22_mbody weight QTL 22 (mouse)Not determined280895334114895334Mouse
15092054Egrme5_mearly growth rate, maternal effect 5 (mouse)282190187118004745Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13463482Mchq17_mmean corpuscular hemoglobin QTL 17 (mouse)267647887101648142Mouse
4142088Parms1_mpatched associated RMS 1 (mouse)Not determined74524117114123532Mouse
10044002Hdl7_mHDL level 7 (mouse)Not determined26300595497006113Mouse
12738429Lfibq18_mliver fibrosis QTL 18 (mouse)25791999191919991Mouse

Markers in Region
UniSTS:485093  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38285,438,209 - 85,439,156UniSTSGRCm38
MGSCv37285,278,366 - 85,279,313UniSTSGRCm37
Celera287,019,603 - 87,020,550UniSTS
Cytogenetic Map2E1UniSTS
UniSTS:494310  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38285,438,125 - 85,439,237UniSTSGRCm38
MGSCv37285,278,282 - 85,279,394UniSTSGRCm37
Celera287,019,519 - 87,020,631UniSTS
Cytogenetic Map2E1UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000099924   ⟹   ENSMUSP00000097508
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,268,469 - 85,269,581 (-)Ensembl
GRCm38.p6 Ensembl285,438,125 - 85,439,237 (-)Ensembl
Ensembl Acc Id: ENSMUST00000216933   ⟹   ENSMUSP00000149952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl285,267,872 - 85,273,983 (-)Ensembl
GRCm38.p6 Ensembl285,437,528 - 85,443,639 (-)Ensembl
RefSeq Acc Id: NM_146434   ⟹   NP_666645
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39285,268,553 - 85,269,500 (-)NCBI
GRCm38285,438,209 - 85,439,156 (-)ENTREZGENE
MGSCv37285,278,366 - 85,279,313 (-)RGD
Celera287,019,603 - 87,020,550 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_666645   ⟸   NM_146434
- UniProtKB: Q8VF74 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000097508   ⟸   ENSMUST00000099924
Ensembl Acc Id: ENSMUSP00000149952   ⟸   ENSMUST00000216933
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VF74-F1-model_v2 AlphaFold Q8VF74 1-315 view protein structure


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3030829 AgrOrtholog
Ensembl Genes ENSMUSG00000075218 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000099924 ENTREZGENE
  ENSMUST00000099924.3 UniProtKB/TrEMBL
  ENSMUST00000216933.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report mmu:258426 UniProtKB/TrEMBL
MGD MGI:3030829 ENTREZGENE
NCBI Gene 258426 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5ak25 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt Q8VF74 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-05-24 Or5ak25  olfactory receptor family 5 subfamily AK member 25  Olfr995  olfactory receptor 995  Symbol and/or name change 5135510 APPROVED