LOC124629328 (H3K4me1 hESC enhancer GRCh37_chr12:21925998-21926996) - Rat Genome Database

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Gene: LOC124629328 (H3K4me1 hESC enhancer GRCh37_chr12:21925998-21926996) Homo sapiens
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Symbol: LOC124629328
Name: H3K4me1 hESC enhancer GRCh37_chr12:21925998-21926996
RGD ID: 151665626
Description: This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells, where it is marked by the H3K4me1 histone modification. A subregion was also validated as a repressive element by Sharpr-MPRA (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in K562 erythroleukemia cells (group: K562 Repressive DNase unmatched - State 4:PromP, inactive/poised promoter, highly conserved). [provided by RefSeq, Jan 2023]
Type: biological-region
RefSeq Status: REVIEWED
Previously known as: Sharpr-MPRA regulatory region 9497
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381221,773,064 - 21,774,062 (+)NCBIGRCh38GRCh38hg38GRCh38
Cytogenetic Map12pNCBI
T2T-CHM13v2.01221,651,746 - 21,652,744 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:27701403   PMID:30033119  


Genomics

Variants

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Variants in LOC124629328
61 total Variants

Expression


Sequence



Additional Information

Database Acc Id Source(s)
COSMIC LOC124629328 COSMIC
GTEx LOC124629328 GTEx
Human Proteome Map LOC124629328 Human Proteome Map
NCBI Gene LOC124629328 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-01-24 LOC124629328  H3K4me1 hESC enhancer GRCh37_chr12:21925998-21926996  LOC124629328  Sharpr-MPRA regulatory region 9497  Symbol and/or name change 5135510 APPROVED