LCMT1 (leucine carboxyl methyltransferase 1) - Rat Genome Database

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Gene: LCMT1 (leucine carboxyl methyltransferase 1) Sus scrofa
Analyze
Symbol: LCMT1
Name: leucine carboxyl methyltransferase 1
RGD ID: 14283094
Description: ENCODES a protein that exhibits protein C-terminal carboxyl O-methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN C-terminal protein methylation (ortholog); negative regulation of protein-containing complex assembly (ortholog); protein methylation (ortholog); ASSOCIATED WITH Embryo Loss (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1321,548,349 - 21,593,667 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Embryo Loss  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA,ISO)

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
LCMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1321,548,349 - 21,593,667 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LCMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381625,111,742 - 25,178,228 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1625,111,731 - 25,178,231 (+)EnsemblGRCh38hg38GRCh38
GRCh371625,123,063 - 25,189,549 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361625,030,548 - 25,097,052 (+)NCBINCBI36Build 36hg18NCBI36
Build 341625,030,675 - 25,097,050NCBI
Celera1623,903,957 - 23,969,431 (+)NCBICelera
Cytogenetic Map16p12.1NCBI
HuRef1623,216,333 - 23,282,516 (+)NCBIHuRef
CHM1_11626,136,800 - 26,203,307 (+)NCBICHM1_1
T2T-CHM13v2.01625,391,240 - 25,457,759 (+)NCBIT2T-CHM13v2.0
Lcmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397122,977,026 - 123,029,581 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7122,969,007 - 123,029,581 (+)EnsemblGRCm39 Ensembl
GRCm387123,377,803 - 123,430,358 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7123,369,784 - 123,430,358 (+)EnsemblGRCm38mm10GRCm38
MGSCv377130,521,496 - 130,573,872 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367123,169,130 - 123,221,506 (+)NCBIMGSCv36mm8
Celera7123,261,211 - 123,313,647 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map767.42NCBI
Lcmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81187,335,173 - 187,391,195 (+)NCBIGRCr8
mRatBN7.21177,904,119 - 177,960,111 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1177,904,139 - 177,960,112 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1186,240,042 - 186,296,278 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01193,426,030 - 193,482,279 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01186,103,922 - 186,159,944 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01193,335,629 - 193,391,620 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1193,335,645 - 193,391,638 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01200,394,399 - 200,450,384 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,242,293 - 182,298,243 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,382,612 - 182,438,493 (+)NCBI
Celera1175,592,825 - 175,648,387 (+)NCBICelera
Cytogenetic Map1q36NCBI
Lcmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554933,431,578 - 3,502,066 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554933,440,832 - 3,499,658 (+)NCBIChiLan1.0ChiLan1.0
LCMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21826,521,239 - 26,587,091 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11631,041,920 - 31,108,409 (+)NCBINHGRI_mPanPan1
PanPan1.11625,352,488 - 25,418,285 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1625,351,814 - 25,418,285 (+)Ensemblpanpan1.1panPan2
LCMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1621,026,125 - 21,066,884 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl621,026,186 - 21,066,876 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha622,601,655 - 22,642,365 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0621,166,737 - 21,207,683 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl621,166,717 - 21,207,673 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1620,970,135 - 21,010,599 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0620,872,708 - 20,913,635 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0621,267,162 - 21,308,117 (-)NCBIUU_Cfam_GSD_1.0
Lcmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344121,256,737 - 121,299,811 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365019,354,565 - 9,397,686 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365019,354,607 - 9,397,675 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LCMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1522,830,677 - 22,897,691 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl522,830,549 - 22,897,682 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660686,831,077 - 6,902,187 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lcmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247829,979,433 - 10,043,475 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247829,974,415 - 10,043,475 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LCMT1
3445 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


RefSeq Acc Id: XM_021086454   ⟹   XP_020942113
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1321,548,349 - 21,593,666 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021086455   ⟹   XP_020942114
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1321,548,349 - 21,593,666 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002342375
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1321,548,349 - 21,593,667 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020942114   ⟸   XM_021086455
- Peptide Label: isoform X2
- UniProtKB: A0A480SGH1 (UniProtKB/TrEMBL),   A0A480SKD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020942113   ⟸   XM_021086454
- Peptide Label: isoform X1
- UniProtKB: A0A4X1UNQ0 (UniProtKB/TrEMBL),   F1RFE3 (UniProtKB/TrEMBL),   A0A8D1JHP9 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000007826 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00045038726 UniProtKB/TrEMBL
  ENSSSCG00070019050 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000008575 ENTREZGENE
  ENSSSCT00000008575.5 UniProtKB/TrEMBL
  ENSSSCT00000028202.4 UniProtKB/TrEMBL
  ENSSSCT00000068219.2 UniProtKB/TrEMBL
  ENSSSCT00000088460.2 UniProtKB/TrEMBL
  ENSSSCT00045067258.1 UniProtKB/TrEMBL
  ENSSSCT00070037875.1 UniProtKB/TrEMBL
  ENSSSCT00070037884.1 UniProtKB/TrEMBL
  ENSSSCT00070037894.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro PPM1 UniProtKB/TrEMBL
  Ppm1/Ppm2/Tcmp UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene LCMT1 ENTREZGENE
PANTHER LEUCINE CARBOXYL METHYLTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR13600 UniProtKB/TrEMBL
Pfam LCM UniProtKB/TrEMBL
PIRSF LCM_mtfrase UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A480SGH1 ENTREZGENE, UniProtKB/TrEMBL
  A0A480SKD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UNQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1UQL0_PIG UniProtKB/TrEMBL
  A0A4X1UQM0_PIG UniProtKB/TrEMBL
  A0A5G2Q927_PIG UniProtKB/TrEMBL
  A0A5G2RAB9_PIG UniProtKB/TrEMBL
  A0A8D1JHP9 ENTREZGENE, UniProtKB/TrEMBL
  F1RFE3 ENTREZGENE, UniProtKB/TrEMBL
  I3LHR5_PIG UniProtKB/TrEMBL