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Gene: LRRC3C (leucine rich repeat containing 3C) Sus scrofa

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Symbol:

LRRC3C

Name:

leucine rich repeat containing 3C

RGD ID:

14282883

Description:

INVOLVED IN potassium ion transmembrane transport (inferred); ASSOCIATED WITH hypertrophic cardiomyopathy 25 (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

leucine-rich repeat-containing protein 3C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	22,398,853 - 22,399,617 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	22,398,463 - 22,409,382 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	22,856,686 - 22,867,632 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hypertrophic cardiomyopathy 25 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

potassium ion transmembrane transport (IEA)

Cellular Component

membrane (IEA)

voltage-gated potassium channel complex (IBA)

Molecular Function

potassium channel activator activity (IBA)

transmembrane transporter binding (IBA)

voltage-gated potassium channel activity (IBA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

LRRC3C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	22,398,853 - 22,399,617 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	22,398,463 - 22,409,382 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	22,856,686 - 22,867,632 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC3C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	39,927,732 - 39,944,999 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	39,927,732 - 39,944,999 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	38,083,985 - 38,101,252 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Celera	17	34,757,993 - 34,761,247 (+)	NCBI		Celera
Cytogenetic Map	17	q21.1	NCBI
HuRef	17	33,891,729 - 33,894,989 (+)	NCBI		HuRef
CHM1_1	17	38,333,429 - 38,336,689 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	40,791,446 - 40,808,715 (+)	NCBI		T2T-CHM13v2.0

Lrrc3c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	98,489,117 - 98,490,412 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	98,489,117 - 98,490,412 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	98,598,291 - 98,599,586 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	98,598,291 - 98,599,586 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	98,460,262 - 98,460,810 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	98,414,909 - 98,415,676 (+)	NCBI		MGSCv36	mm8
Celera	11	108,253,349 - 108,253,897 (+)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	62.12	NCBI

Lrrc3c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	84,104,722 - 84,107,913 (+)	NCBI		GRCr8
mRatBN7.2	10	83,608,797 - 83,610,128 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	83,608,483 - 83,611,646 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	88,552,256 - 88,553,589 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	88,050,333 - 88,051,666 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	83,443,026 - 83,444,359 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	86,554,761 - 86,565,800 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	86,564,928 - 86,565,695 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	86,360,624 - 86,362,092 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	87,422,134 - 87,422,901 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	10	82,346,858 - 82,358,420 (+)	NCBI		Celera
Cytogenetic Map	10	q31	NCBI

Lrrc3c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	14,644,305 - 14,649,084 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	14,644,464 - 14,647,078 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC3C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	25,008,224 - 25,027,378 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	26,903,050 - 26,922,994 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	17,344,449 - 17,347,977 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	17,563,906 - 17,567,160 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	17,563,906 - 17,567,160 (-)	Ensembl	panpan1.1		panPan2

LRRC3C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	22,581,358 - 22,596,646 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	22,581,615 - 22,582,436 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	9	22,581,615 - 22,582,436 (-)	NCBI	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	9	23,374,231 - 23,375,222 (-)	NCBI		ROS_Cfam_1.0
UU_Cfam_GSD_1.0	9	22,531,121 - 22,532,111 (-)	NCBI		UU_Cfam_GSD_1.0

Lrrc3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	21,985,342 - 21,986,943 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	15,088,079 - 15,089,797 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	15,088,555 - 15,090,587 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC3C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	66,222,782 - 66,241,944 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	37,135,419 - 37,137,004 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc3c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	3,198,477 - 3,199,584 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	3,196,900 - 3,200,396 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in LRRC3C
377 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013979562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU928026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000019037 ⟹ ENSSSCP00000018532

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	22,398,853 - 22,399,617 (-)	Ensembl

RefSeq Acc Id:

XM_013979562 ⟹ XP_013835016

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	22,398,463 - 22,409,382 (-)	NCBI

Sequence:

show sequence

GCCACAGTGGGAACTCCCCAGGCGCTTGTTAAGTGCTTCACTGCCTTGTTAGTTAATTTCCACA
AGCACAGGAAGTAGGTACTGCTCCTATTCTCCTATGGGGAGGAAACAGATTTAGAGGTTTAGGG
ACTTATTCAAGGTCATTTGGTAAGAAGGTGGCAGAGTGGGTTCCGACCACAATGACTCCTGGTG
AGAAGGGTATTGTCTGGGGAGCCACAGCTGGAAGACGTCCTCAGAAGGGGCGGCGATCACGGAG
GGGAGCCCAGGACAGGGCGCCCCAGGCAGGGTTTCCGAGAGGTCTTGGGTCAGCCTCAGTGTGA
TGTTTACCCTTCTCTTTCTAGACCATAAGGCTCCGTTCCGAGTTACAGACAACGTGGATTCAAA
GGGAGGTTTGACAGTGAAATTACCTGAAAACATGATGTTTGAAGTGGCCACCTACAGGTCCAGG
AAGCACAGCGTCGAGGTCTTGGGGACCCGGATACCCAGGCAACTCCTGGCTGCCCTTGAGAACA
CCTCCTGCTCCACTCCAGGACTATGCCAATCTGTGGCCATGCTCCCACCAGCTGGTCACCTCCT
GTCCCTGCTGCTGGTGATAGGCACAGGGGGCAGTGTGCCCAGCCACCCAGCATCTCCCCAAGGC
TGCTACGTGGCAGAGGAGGCTGGGGAGCGGACATTCCGCTGTAGCCAGGCGGGCCTGAGCGCCG
TGCCCACCGGCATCCCCAACGACACCCGCAAGCTCTACCTGGATGCCAACCAGCTGGTGACAGT
GCCCGCGGGCGCCTTTCAGCACCTTCCTGTCCTGGAGGAGCTGGATCTGTCCCATAACATCCTA
GCCCACCTCTCGGGAGCCGCTTTCCAGGGCCTGGCAGGCACGCTGCGCCACCTCGACCTCTCTG
CCAACCAGCTGGCCTCGGTGCCCGTGGAAGCCTTCATGGGGCTGCAGATCCAAGTGAACCTGTC
TGCCAACCCATGGCGCTGTGACTGTGCCCTCCAGGAGGTGCTCAGGCAGGTGAGGCTGGCACCA
GGCACTGGGACGGGCATCGTGTGTGGCCCAGGAGCCCGACCAGACCTCGTGGGCCAGGAGTTCC
TGCCACTGGCAGGGGAGGAAGAGCTGTGTGGGGCGGGGCGGGGTGGGGCCCAGAGGAGCACCGA
CGTGGCCCTCCTGGTCACCATGGGGGGCTGGCTGGTGCTCGTGGTGGCTTATCTGGTCCACTAC
GTGTGGCAGAACCGAGATGAGAGCCGCCGTCCTCTCAAGCGGGTCCGCATGCTGCCTGTGCGCT
CTGAGGACTCCTCCATCCTCAGCACAGTAGTCTGATGACCAAGGCCACCCCTCTGGCCCCGTGC
CCTTTGCCCTCTCCTCCCTTCGACCCCTCCCCCCTCCTCTGCAGCCCCTTCCCATCCCCCAAGG
CCATCCCTCTTCTCCCTCTGTCTCCTGGAAAGGTCTGCTCTCTCTCACACCACCAACACCATCT
TTGGTGCCTACTCTGGGCTGGGATTGTGCTAGACTCAGATGCCCAGAGCCAAGTCGGGGGACAG
GGGACGACAGAACAGAGAACGGCCGCAGGCAGGGTGTGTGCCAACTCAGAGGAGGAGCGGGCAG
CTTGAGAGCGTAGCAGAGGTAATCTCAAAGCTCTACTTATGGATGTTTGATCTGACTCTTCAAG
AATGAGGAGACCCAGGAGGTCCTGTCATGGCTCAGTGGTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013835016	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000018532.4
	ENSSSCP00040001776.1
	ENSSSCP00060042429.1

RefSeq Acc Id:

XP_013835016 ⟸ XM_013979562

- UniProtKB:

A0A8D1BTD4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFTLLFLDHKAPFRVTDNVDSKGGLTVKLPENMMFEVATYRSRKHSVEVLGTRIPRQLLAALEN
TSCSTPGLCQSVAMLPPAGHLLSLLLVIGTGGSVPSHPASPQGCYVAEEAGERTFRCSQAGLSA
VPTGIPNDTRKLYLDANQLVTVPAGAFQHLPVLEELDLSHNILAHLSGAAFQGLAGTLRHLDLS
ANQLASVPVEAFMGLQIQVNLSANPWRCDCALQEVLRQVRLAPGTGTGIVCGPGARPDLVGQEF
LPLAGEEELCGAGRGGAQRSTDVALLVTMGGWLVLVVAYLVHYVWQNRDESRRPLKRVRMLPVR
SEDSSILSTVV

hide sequence

Ensembl Acc Id:

ENSSSCP00000018532 ⟸ ENSSSCT00000019037

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000017484	Ensembl, UniProtKB/TrEMBL
	ENSSSCG00040004032	UniProtKB/TrEMBL
	ENSSSCG00060071651	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000019037.4	UniProtKB/TrEMBL
	ENSSSCT00040005140.1	UniProtKB/TrEMBL
	ENSSSCT00060097864.1	UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	Dev_Immune_Receptor	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	LRR_dom_sf	UniProtKB/TrEMBL
NCBI Gene	LRRC3C	ENTREZGENE
PANTHER	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3C	UniProtKB/TrEMBL
	SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN	UniProtKB/TrEMBL
Pfam	LRR_8	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A0A8D1BTD4	ENTREZGENE, UniProtKB/TrEMBL
	F1RXB1_PIG	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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