FHL5 (four and a half LIM domains 5) - Rat Genome Database

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Gene: FHL5 (four and a half LIM domains 5) Sus scrofa
Analyze
Symbol: FHL5
Name: four and a half LIM domains 5
RGD ID: 14246039
Description: ENCODES a protein that exhibits metal ion binding (inferred); transcription coactivator activity (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH migraine (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: four and a half LIM domains protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl163,705,936 - 63,754,067 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1163,705,864 - 63,754,079 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2172,074,158 - 72,120,937 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
migraine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)
Z disc  (IBA)

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:17407547   PMID:30032202  


Genomics

Comparative Map Data
FHL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl163,705,936 - 63,754,067 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1163,705,864 - 63,754,079 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2172,074,158 - 72,120,937 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FHL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38696,562,574 - 96,618,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl696,562,548 - 96,618,626 (+)EnsemblGRCh38hg38GRCh38
GRCh37697,010,450 - 97,066,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36697,117,156 - 97,171,233 (+)NCBINCBI36Build 36hg18NCBI36
Build 34697,117,155 - 97,171,233NCBI
Celera697,652,191 - 97,706,601 (+)NCBICelera
Cytogenetic Map6q16.1NCBI
HuRef694,444,613 - 94,498,689 (+)NCBIHuRef
CHM1_1697,272,425 - 97,326,515 (+)NCBICHM1_1
T2T-CHM13v2.0697,734,473 - 97,790,488 (+)NCBIT2T-CHM13v2.0
Fhl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39425,199,907 - 25,242,852 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl425,199,908 - 25,242,876 (-)EnsemblGRCm39 Ensembl
GRCm38425,199,907 - 25,242,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl425,199,908 - 25,242,876 (-)EnsemblGRCm38mm10GRCm38
MGSCv37425,127,056 - 25,170,023 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36425,290,539 - 25,333,506 (-)NCBIMGSCv36mm8
Celera424,935,116 - 24,977,805 (-)NCBICelera
Cytogenetic Map4A3NCBI
cM Map410.58NCBI
Fhl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8543,704,493 - 43,753,356 (-)NCBIGRCr8
mRatBN7.2538,907,941 - 38,956,759 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl538,907,946 - 38,956,552 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx541,005,013 - 41,053,550 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0542,604,019 - 42,652,566 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0542,537,365 - 42,585,904 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0539,564,241 - 39,611,273 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl539,564,242 - 39,611,053 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0544,191,766 - 44,239,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4540,253,199 - 40,301,542 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1540,253,378 - 40,301,721 (-)NCBI
Celera537,834,932 - 37,882,495 (-)NCBICelera
Cytogenetic Map5q21NCBI
Fhl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541122,583,292 - 22,619,281 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541122,583,314 - 22,619,281 (+)NCBIChiLan1.0ChiLan1.0
FHL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25116,602,744 - 116,663,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16114,480,915 - 114,541,811 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0694,397,172 - 94,450,318 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1698,283,399 - 98,337,256 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl698,283,399 - 98,337,256 (+)Ensemblpanpan1.1panPan2
FHL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11255,027,765 - 55,074,717 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1255,027,784 - 55,071,570 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1254,841,502 - 54,888,010 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01255,844,813 - 55,891,117 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1255,844,858 - 55,887,960 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11255,180,133 - 55,226,376 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01255,041,040 - 55,087,562 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01255,289,016 - 55,335,600 (+)NCBIUU_Cfam_GSD_1.0
Fhl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494689,602,418 - 89,642,732 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366991,084,550 - 1,124,676 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366991,084,578 - 1,124,783 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FHL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11377,298,280 - 77,351,797 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1377,298,353 - 77,350,157 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604049,594,298 - 49,645,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fhl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248108,747,613 - 8,792,532 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248108,747,834 - 8,792,527 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FHL5
1315 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence


Ensembl Acc Id: ENSSSCT00000004796   ⟹   ENSSSCP00000004683
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl163,705,937 - 63,754,067 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000068060   ⟹   ENSSSCP00000063765
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl163,705,936 - 63,751,989 (+)Ensembl
RefSeq Acc Id: NM_001243314   ⟹   NP_001230243
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1163,706,018 - 63,752,163 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021084440   ⟹   XP_020940099
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1163,705,864 - 63,754,079 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021084477   ⟹   XP_020940136
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1163,705,864 - 63,754,079 (+)NCBI
Sequence:
RefSeq Acc Id: XP_020940099   ⟸   XM_021084440
- Peptide Label: isoform X1
- UniProtKB: A0A4X1VJU8 (UniProtKB/TrEMBL),   A0A5G2QZT7 (UniProtKB/TrEMBL),   A0A8D1A3S2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020940136   ⟸   XM_021084477
- Peptide Label: isoform X2
- UniProtKB: A0A4X1VD49 (UniProtKB/TrEMBL),   F1RY03 (UniProtKB/TrEMBL),   A0A5G2QZT7 (UniProtKB/TrEMBL),   A0A8D1A3S2 (UniProtKB/TrEMBL),   A0A8D1WR61 (UniProtKB/TrEMBL),   A0A8D1A6S7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230243   ⟸   NM_001243314
- UniProtKB: F1RY03 (UniProtKB/TrEMBL),   A0A4X1VD49 (UniProtKB/TrEMBL),   A0A5G2QZT7 (UniProtKB/TrEMBL),   A0A8D1A3S2 (UniProtKB/TrEMBL),   A0A8D1WR61 (UniProtKB/TrEMBL),   A0A8D1A6S7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000063765   ⟸   ENSSSCT00000068060
Ensembl Acc Id: ENSSSCP00000004683   ⟸   ENSSSCT00000004796
Protein Domains
LIM zinc-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000004340 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015055743 UniProtKB/TrEMBL
  ENSSSCG00025072954 UniProtKB/TrEMBL
  ENSSSCG00030058302 UniProtKB/TrEMBL
  ENSSSCG00035051271 UniProtKB/TrEMBL
  ENSSSCG00040050070 UniProtKB/TrEMBL
  ENSSSCG00045024244 UniProtKB/TrEMBL
  ENSSSCG00050015404 UniProtKB/TrEMBL
  ENSSSCG00055005148 UniProtKB/TrEMBL
  ENSSSCG00060073037 UniProtKB/TrEMBL
  ENSSSCG00065076458 UniProtKB/TrEMBL
  ENSSSCG00070024393 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000004796 ENTREZGENE
  ENSSSCT00000004796.4 UniProtKB/TrEMBL
  ENSSSCT00000068060 ENTREZGENE
  ENSSSCT00000068060.1 UniProtKB/TrEMBL
  ENSSSCT00015074309.1 UniProtKB/TrEMBL
  ENSSSCT00015074399.1 UniProtKB/TrEMBL
  ENSSSCT00025100358.1 UniProtKB/TrEMBL
  ENSSSCT00030081329.1 UniProtKB/TrEMBL
  ENSSSCT00035068288.1 UniProtKB/TrEMBL
  ENSSSCT00035068292.1 UniProtKB/TrEMBL
  ENSSSCT00040067560.1 UniProtKB/TrEMBL
  ENSSSCT00045041327.1 UniProtKB/TrEMBL
  ENSSSCT00050020871.1 UniProtKB/TrEMBL
  ENSSSCT00055010064.1 UniProtKB/TrEMBL
  ENSSSCT00060099810.1 UniProtKB/TrEMBL
  ENSSSCT00065105593.1 UniProtKB/TrEMBL
  ENSSSCT00065105598.1 UniProtKB/TrEMBL
  ENSSSCT00070048723.1 UniProtKB/TrEMBL
  ENSSSCT00070048726.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro FHL5_LIM2 UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report ssc:100152075 UniProtKB/TrEMBL
NCBI Gene FHL5 ENTREZGENE
PANTHER FOUR AND A HALF LIM DOMAINS PROTEIN 5 UniProtKB/TrEMBL
  PTHR24205 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A4X1VD49 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1VJU8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QZT7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1A3S2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1A6S7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WR61 ENTREZGENE, UniProtKB/TrEMBL
  F1RY03 ENTREZGENE
UniProt Secondary F1RY03 UniProtKB/TrEMBL
VGNC ID VGNC:88130 ENTREZGENE