ARHGEF19 (Rho guanine nucleotide exchange factor 19) - Rat Genome Database

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Gene: ARHGEF19 (Rho guanine nucleotide exchange factor 19) Sus scrofa
Analyze
Symbol: ARHGEF19
Name: Rho guanine nucleotide exchange factor 19
RGD ID: 14242750
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); regulation of actin cytoskeleton organization (ortholog); wound healing (ortholog); ASSOCIATED WITH cataract 6 multiple types (ortholog); chromosome 1p36 deletion syndrome (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,317,823 - 75,335,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,317,811 - 75,335,292 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,633,523 - 69,650,991 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ARHGEF19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,317,823 - 75,335,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,317,811 - 75,335,292 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,633,523 - 69,650,991 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38116,197,854 - 16,212,652 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl116,197,854 - 16,212,652 (-)EnsemblGRCh38hg38GRCh38
GRCh37116,524,349 - 16,539,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,397,186 - 16,411,691 (-)NCBINCBI36Build 36hg18NCBI36
Build 34116,269,904 - 16,284,410NCBI
Celera115,004,527 - 15,018,992 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,042,069 - 15,056,569 (-)NCBIHuRef
CHM1_1116,323,212 - 16,337,699 (-)NCBICHM1_1
T2T-CHM13v2.0115,639,202 - 15,653,982 (-)NCBIT2T-CHM13v2.0
Arhgef19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,966,916 - 140,985,226 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,966,810 - 140,984,875 (+)EnsemblGRCm39 Ensembl
GRCm384141,239,605 - 141,257,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,239,499 - 141,257,564 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,798,799 - 140,813,477 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,514,960 - 140,529,638 (+)NCBIMGSCv36mm8
Celera4143,051,066 - 143,065,764 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.53NCBI
Arhgef19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,818,840 - 158,837,196 (+)NCBIGRCr8
mRatBN7.25153,536,038 - 153,554,203 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,536,013 - 153,554,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,225,060 - 156,243,226 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,998,343 - 158,016,509 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,987,537 - 158,005,703 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,754,954 - 159,773,699 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,755,535 - 159,773,699 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,471,143 - 163,494,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,091,794 - 160,109,955 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,105,466 - 160,120,135 (+)NCBI
Celera5151,900,596 - 151,919,574 (+)NCBICelera
Cytogenetic Map5q36NCBI
Arhgef19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,077,806 - 2,088,880 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,073,009 - 2,087,291 (+)NCBIChiLan1.0ChiLan1.0
ARHGEF19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,704,388 - 210,723,902 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,957,569 - 209,972,560 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0115,334,564 - 15,354,061 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1116,327,135 - 16,342,004 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl116,327,135 - 16,342,009 (-)Ensemblpanpan1.1panPan2
ARHGEF19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,484,068 - 81,499,961 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,486,146 - 81,499,584 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,016,450 - 78,036,107 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0282,126,388 - 82,146,073 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,132,250 - 82,146,085 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,879,368 - 78,899,043 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,896,590 - 79,916,272 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,964,447 - 80,984,130 (+)NCBIUU_Cfam_GSD_1.0
Arhgef19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,881,800 - 37,897,803 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364743,706,100 - 3,719,641 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364743,706,584 - 3,716,010 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,088,130 - 116,107,499 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20116,096,423 - 116,107,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605419,583,206 - 19,602,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,325,151 - 2,348,631 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,325,151 - 2,339,161 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ARHGEF19
398 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 19 3 2 5 14 12 19 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000003858   ⟹   ENSSSCP00000003770
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,317,823 - 75,335,270 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000044209   ⟹   ENSSSCP00000033378
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,317,823 - 75,328,704 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000052573   ⟹   ENSSSCP00000049624
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl675,317,823 - 75,328,704 (-)Ensembl
RefSeq Acc Id: XM_003127633   ⟹   XP_003127681
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,332,254 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021095412   ⟹   XP_020951071
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,329,533 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021095413   ⟹   XP_020951072
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,329,534 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021095414   ⟹   XP_020951073
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,333,100 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021095415   ⟹   XP_020951074
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,335,292 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021095416   ⟹   XP_020951075
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1675,317,811 - 75,333,052 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020951074   ⟸   XM_021095415
- Peptide Label: isoform X3
- UniProtKB: A0A8D1Z7M2 (UniProtKB/TrEMBL),   F1SUS7 (UniProtKB/TrEMBL),   A0A8D0W3N4 (UniProtKB/TrEMBL),   A0A8D1LVM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951073   ⟸   XM_021095414
- Peptide Label: isoform X3
- UniProtKB: A0A8D1Z7M2 (UniProtKB/TrEMBL),   F1SUS7 (UniProtKB/TrEMBL),   A0A8D0W3N4 (UniProtKB/TrEMBL),   A0A8D1LVM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951075   ⟸   XM_021095416
- Peptide Label: isoform X3
- UniProtKB: A0A8D1Z7M2 (UniProtKB/TrEMBL),   F1SUS7 (UniProtKB/TrEMBL),   A0A8D0W3N4 (UniProtKB/TrEMBL),   A0A8D1LVM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003127681   ⟸   XM_003127633
- Peptide Label: isoform X3
- UniProtKB: F1SUS7 (UniProtKB/TrEMBL),   A0A8D1Z7M2 (UniProtKB/TrEMBL),   A0A8D0W3N4 (UniProtKB/TrEMBL),   A0A8D1LVM5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951072   ⟸   XM_021095413
- Peptide Label: isoform X2
- UniProtKB: A0A8D0TVW3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020951071   ⟸   XM_021095412
- Peptide Label: isoform X1
- UniProtKB: A0A287B0E6 (UniProtKB/TrEMBL),   A0A8D0ZA49 (UniProtKB/TrEMBL),   A0A8D0TVW3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000033378   ⟸   ENSSSCT00000044209
Ensembl Acc Id: ENSSSCP00000049624   ⟸   ENSSSCT00000052573
Ensembl Acc Id: ENSSSCP00000003770   ⟸   ENSSSCT00000003858
Protein Domains
DH   PH   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000003472 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015012068 UniProtKB/TrEMBL
  ENSSSCG00025004491 UniProtKB/TrEMBL
  ENSSSCG00030024730 UniProtKB/TrEMBL
  ENSSSCG00035025864 UniProtKB/TrEMBL
  ENSSSCG00040046910 UniProtKB/TrEMBL
  ENSSSCG00045031869 UniProtKB/TrEMBL
  ENSSSCG00050024722 UniProtKB/TrEMBL
  ENSSSCG00055011891 UniProtKB/TrEMBL
  ENSSSCG00060023789 UniProtKB/TrEMBL
  ENSSSCG00065054183 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000003858 ENTREZGENE
  ENSSSCT00000003858.3 UniProtKB/TrEMBL
  ENSSSCT00015015879.1 UniProtKB/TrEMBL
  ENSSSCT00015015956.1 UniProtKB/TrEMBL
  ENSSSCT00025006027.1 UniProtKB/TrEMBL
  ENSSSCT00030034511.1 UniProtKB/TrEMBL
  ENSSSCT00035034084.1 UniProtKB/TrEMBL
  ENSSSCT00035034089.1 UniProtKB/TrEMBL
  ENSSSCT00040063178.1 UniProtKB/TrEMBL
  ENSSSCT00045054407.1 UniProtKB/TrEMBL
  ENSSSCT00050033281.1 UniProtKB/TrEMBL
  ENSSSCT00055023268.1 UniProtKB/TrEMBL
  ENSSSCT00060032292.1 UniProtKB/TrEMBL
  ENSSSCT00065074224.1 UniProtKB/TrEMBL
  ENSSSCT00065074231.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  Ephexin-like UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_ephexin UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report ssc:100521628 UniProtKB/TrEMBL
NCBI Gene ARHGEF19 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE EXCHANGE FACTOR UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19 UniProtKB/TrEMBL
Pfam RhoGEF UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48065 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A287B0E6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TVW3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0W3N4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0ZA49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1LVM5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1Z7M2 ENTREZGENE, UniProtKB/TrEMBL
  F1SUS7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:85492 ENTREZGENE