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Gene: ARHGEF19 (Rho guanine nucleotide exchange factor 19) Pan paniscus

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Symbol:

ARHGEF19

Name:

Rho guanine nucleotide exchange factor 19

RGD ID:

11696761

Description:

ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); regulation of actin cytoskeleton organization (ortholog); wound healing (ortholog); ASSOCIATED WITH cataract 6 multiple types (ortholog); chromosome 1p36 deletion syndrome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC106633989; uncharacterized LOC106633989; uncharacterized protein LOC106633989

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	210,704,388 - 210,723,902 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	209,957,569 - 209,972,560 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	15,334,564 - 15,354,061 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	16,327,135 - 16,342,004 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	16,327,135 - 16,342,009 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cataract 6 multiple types (ISO)

chromosome 1p36 deletion syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of GTPase activity (ISO)

regulation of actin cytoskeleton organization (IEA,ISO)

wound healing (IEA,ISO)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ARHGEF19
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	210,704,388 - 210,723,902 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	209,957,569 - 209,972,560 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	15,334,564 - 15,354,061 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	16,327,135 - 16,342,004 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	16,327,135 - 16,342,009 (-)	Ensembl	panpan1.1		panPan2

ARHGEF19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	16,197,854 - 16,212,652 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	16,197,854 - 16,212,652 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	16,524,349 - 16,539,147 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	16,397,186 - 16,411,691 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	16,269,904 - 16,284,410	NCBI
Celera	1	15,004,527 - 15,018,992 (-)	NCBI		Celera
Cytogenetic Map	1	p36.13	NCBI
HuRef	1	15,042,069 - 15,056,569 (-)	NCBI		HuRef
CHM1_1	1	16,323,212 - 16,337,699 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	15,639,202 - 15,653,982 (-)	NCBI		T2T-CHM13v2.0

Arhgef19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	140,966,916 - 140,985,226 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	140,966,810 - 140,984,875 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	141,239,605 - 141,257,915 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	141,239,499 - 141,257,564 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	140,798,799 - 140,813,477 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	140,514,960 - 140,529,638 (+)	NCBI		MGSCv36	mm8
Celera	4	143,051,066 - 143,065,764 (+)	NCBI		Celera
Cytogenetic Map	4	D3	NCBI
cM Map	4	73.53	NCBI

Arhgef19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	158,818,840 - 158,837,196 (+)	NCBI		GRCr8
mRatBN7.2	5	153,536,038 - 153,554,203 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	153,536,013 - 153,554,203 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	156,225,060 - 156,243,226 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	157,998,343 - 158,016,509 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	157,987,537 - 158,005,703 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	159,754,954 - 159,773,699 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	159,755,535 - 159,773,699 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	163,471,143 - 163,494,854 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	160,091,794 - 160,109,955 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	160,105,466 - 160,120,135 (+)	NCBI
Celera	5	151,900,596 - 151,919,574 (+)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Arhgef19
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955527	2,077,806 - 2,088,880 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955527	2,073,009 - 2,087,291 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARHGEF19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	81,484,068 - 81,499,961 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	81,486,146 - 81,499,584 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	78,016,450 - 78,036,107 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	82,126,388 - 82,146,073 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	82,132,250 - 82,146,085 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	78,879,368 - 78,899,043 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	79,896,590 - 79,916,272 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	80,964,447 - 80,984,130 (+)	NCBI		UU_Cfam_GSD_1.0

Arhgef19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	37,881,800 - 37,897,803 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936474	3,706,100 - 3,719,641 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936474	3,706,584 - 3,716,010 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARHGEF19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	75,317,823 - 75,335,270 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	75,317,811 - 75,335,292 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	69,633,523 - 69,650,991 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARHGEF19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	116,088,130 - 116,107,499 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	116,096,423 - 116,107,884 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	19,583,206 - 19,602,766 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arhgef19
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624764	2,325,151 - 2,348,631 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624764	2,325,151 - 2,339,161 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003806237	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008951541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024926318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034956261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000062206 ⟹ ENSPPAP00000039296

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	16,327,135 - 16,342,009 (-)	Ensembl

RefSeq Acc Id:

XM_003806237 ⟹ XP_003806285

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	210,704,388 - 210,723,902 (+)	NCBI
NHGRI_mPanPan1	1	209,957,570 - 209,972,559 (+)	NCBI
Mhudiblu_PPA_v0	1	15,334,564 - 15,350,510 (-)	NCBI
PanPan1.1	1	16,327,135 - 16,342,003 (-)	NCBI

Sequence:

show sequence

AGGGGGCGGGGAGCAGGCACGTTGAGACAGCCGCCTGCCTCTCTCTGCAAGGTTCCCTCCTCCT
TCACCTCCCCCTCCCTGCCCCACACAATACCCAGGAGCTTGCCTTGCTCGGCTCTGGGGCCATG
CTGACATGCTGACATCGCCCCCTGAGGACTTGGCTGCAACCCCAGAGCCCCCAGGGTGTCCCGG
AGCCCTGGACCGTGCTGGCAGCTGGACGGAGCTCCCTGGCTGAGGGCCAGGTGGGTGGCAGAGC
AAAAGAGGAATGGACTGTGGGCCACCTGCTACCCTCCAGCCCCACCTGACTGGGCCACCTGGCA
CTGCCCACCACCCTGTAGCAGTGTGCCAGCAGGAGAGTCTGTCCTTTGCAGAGCTGCCCGCCCT
GAAGCCCCCGAGCCCAGTGTGTCTGGACCTTTTCCCTGTTGCCCCAGAGGAGCTTCGGGCTCCT
GGCAGCCGCTGGTCTCTGGGGACCCCTGCCCCTCTCCAAGGGTTGCTATGGCCATCATCCCCAG
GAGGCTCAGATACAGAGATCACCAGCGGGGGGATGCGGCCCAGCAGGGCTGGCAGCTGGCCACA
CTGTCCTGGTGCCCAGCCCCCAGCTCTGGAGGGACCCTGGAGTCCCCGACACACACAGCCACAG
CGCCGGGCCAGCCACGGCTCGGAGAAGAAGTCTGCCTGGCGCAAGATGCGGGTGTACCAGCGTG
AAGAGGTCCCCGGCTGCCCCGAGGCCCACGCTGTCTTCCTAGAGCCTGGCCAGGTAGTGCAAGA
GCAGGCCCTGAGCACAGAGGAGCCCAGGGTGGAGCTGTCTGGGTCCACCCGAGTGAGCCTCGAA
GGTCCTGAGCGGAGGCGCTTCTCGGCATCGGAGCTGATGACCCGGCTGCACTCTTCTCTGCGCC
TGGGGCGGAATTCAGCAGCCCGGGCACTCATCTCTGGGTCAGGCATCGGAGCAGCCCGGGAAGG
GAAAGCATCTGGAATGGAGGCTCGAAGTGTAGAGATGAGCGGGGACCGGGTGTCGCGGCCAGCC
CCTGGTGACTCACGAGAGGGCCATGGCGATTGGTCCGAGCCCAGGCTAGACACACAGGAAGAGC
CGCCTTTGGGGTCCAGGAGCACCAACGAGCGGCGCCAGTCTCGATTCCTCCTTAACTCCGTCCT
CTATCAGGAATACAGCGACGTGGCCAGCGCCCGCGAACTGCGGCGGCAGCAGCGCGAGGAGGAG
GGCCCGGGGGACGAGGCCGAGGGCGCAGAGGAGGGGCCGGGGCCACCGCGCGCTAACCTCTCCC
CCAGCAGCTCCTTCCGGGCGCAGCGCTCGGCGCGAGGCTCCACCTTCTCGCTGTGGCAGGATAT
CCCCGACGTACGCGGCAGCGGCGTCCTGGCCACGCTGAGCCTGCGGGACTGCAAGCTGCAGGAG
GCCAAGTTTGAGCTGATCACCTCCGAGGCCTCCTACATCCACAGCCTGTCGGTGGCTGTGGGCC
ATTTCTTAGGCTCTGCCGAGCTGAGCGAGTGTCTGGGGGCGCAGGACAAACAGTGGCTGTTTTC
CAAACTGCCCGAGGTCAAGAGCACCAGCGAGAGGTTCCTGCAGGACCTGGAGCAGCGGCTGGAG
GCAGATGTGCTGCGCTTCAGCGTGTGCGACGTGGTGCTGGACCACTGCCCGGCCTTCCGCAGAG
TCTACCTGCCCTATGTCACCAACCAGGCCTACCAGGAGCGCACCTACCAGCGCCTGCTCCTGGA
GAACCCCAGGTTCCCTGGCATCCTGGCTCGCCTGGAGGAGTCTCCTGTGTGCCAGCGTCTGCCC
CTTACTTCCTTCCTTATCCTGCCCTTCCAGAGGATCACCCGCCTCAAGATGTTGGTGGAGAACA
TCCTGAAGCGGACAGCACAGGGCTCTGAAGACGAAGACATGGCCACCAAGGCCTTCAATGCGCT
CAAGGAGCTGGTGCAGGAGTGCAATGCTAGTGTACAGTCCATGAAGAGGACAGAGGAACTCATC
CACCTGAGCAAGAAGATCCACTTTGAGGGCAAGATTTTCCCGCTGATCTCTCAGGCCCGCTGGC
TGGTTCGGCATGGAGAGTTGGTAGAGCTGGCACCACTGCCTGCAGCACCCCCTGCCAAGCTGAA
GCTGTCCAGCAAGGCAGTCTACCTCCACCTCTTCAATGACTGCTTGCTGCTCTCTCGGCGGAAG
GAGCTAGGGAAGTTTGCCGTTTTCGTCCATGCCAAGATGGCTGAGCTGCAGGTGCGGGACCTGA
GCCTGAAGCTGCAGGGCATCCCCGGCCACGTGTTCCTCCTCCAGCTCCTCCACGGGCAGCACAT
GAAGCACCAGTTCCTGCTGCGGGCCCGGACGGAAAGTGAGAAGCAGCGATGGATCTCAGCCTTG
TGCCCCTCCAGCCCCCAGGAGGACAAGGAGGTCATCAGTGACGGGGAAGATTGCCCCCAGGTTC
AGTGTGTTAGGACATACAAGGCACTGCACCCAGATGAGCTGACCTTGGAGAAGACTGACATCCT
GGCAGTGAGGACCTGGACCAGTGACGGCTGGCTGGAAGGGGTCCGCCTGGCAGATGGTGAGAAG
GGGTGGGTGCCCCAGGCCTATGTGGAAGAGATCAGCAGCCTCAGCGCCCGCCTCCGAAACCTCC
GGGAGAATAAGCGAGTCACAAGTGCCACCAGCAAACTGGGGGAGGCTCCTGTGTGATGGGCAGC
CATGGCCTAGGACCCCACCTCCATGCCTGGCTCCTGGATGGTCCTGGAGGGGCCTGCAGTGTCT
CCATTCCCCAAGCTGCTCCTGCTGGCACTTCGCTTCTGTGGCCTTGGCATTGAGGGCACAGGCT
GGACACAGGAATGGGGGCGCCTCCAGAGGGTCTCTCCGTCCTCATGCTCCTCAGTGTCCACACT
TCAAGGCCAAGGGTAGTTTCTTCCTCTGACATGGGGACCATAACAGGTGATCACTGATACCTGG
CAAAGACTGGGGCCGTCTCCTTTCTATGTCCTCAATCCTGCCTGACTCTTGGTCCTTCTGGCAG
GGACCTGGCTGGGGAACGTTCTGGTGCTGATGGTGCTGGGACCTATATGTATATTTATATATAT
CTGGGGTCTTGTCTACCACCTCCCCTGGTCAGAGCCCGAGTGGGTGCTGGTTGCTGTGTCTTGT
CTGTAAATAAACTCCTATCATGCCTTTGCTTGGAGTCTGTGATCCATCTGATGCTGCCCCCACC
CCCACAGTCCTATTTTCCCAGCTAAAGACCAGGAGAGTCTCCGGCTGGCTCCCAACTGGGGCTT
TGCATTTCTCTAGAGTTCATCTCTGAGCTGTAAGGGTGACCAGGGGACAGGGGGACGATTGTGT
ATCAGCTAGGCTGCTTTTGGCTGCAAGTAACAAAATATCAGATACAAATAGGCTTAAACATTAA
AGAGATTTGATTAGTTCTT

hide sequence

RefSeq Acc Id:

XM_008951541 ⟹ XP_008949789

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	210,704,388 - 210,723,902 (+)	NCBI
NHGRI_mPanPan1	1	209,957,569 - 209,972,560 (+)	NCBI
Mhudiblu_PPA_v0	1	15,334,564 - 15,350,510 (-)	NCBI
PanPan1.1	1	16,327,135 - 16,342,004 (-)	NCBI

Sequence:

show sequence

AAGGGGGCGGGGAGCAGGCACGTTGAGACAGCCGCCTGCCTCTCTCTGCAAGGTTCCCTCCTCC
TTCACCTCCCCCTCCCTGCCCCACACAATACCCAGGAGCTTGCCTTGCTCGGCTCTGGGGCCAT
GCTGACATGCTGACATCGCCCCCTGAGGACTTGGCTGCAACCCCAGAGCCCCCAGGGTGTCCCG
GAGCCCTGGACCGTGCTGGCAGCTGGACGGAGCTCCCTGGCTGAGGTCTGATATCTTCGCTTCT
GCAGGGCCAGGTGGGTGGCAGAGCAAAAGAGGAATGGACTGTGGGCCACCTGCTACCCTCCAGC
CCCACCTGACTGGGCCACCTGGCACTGCCCACCACCCTGTAGCAGTGTGCCAGCAGGAGAGTCT
GTCCTTTGCAGAGCTGCCCGCCCTGAAGCCCCCGAGCCCAGTGTGTCTGGACCTTTTCCCTGTT
GCCCCAGAGGAGCTTCGGGCTCCTGGCAGCCGCTGGTCTCTGGGGACCCCTGCCCCTCTCCAAG
GGTTGCTATGGCCATCATCCCCAGGAGGCTCAGATACAGAGATCACCAGCGGGGGGATGCGGCC
CAGCAGGGCTGGCAGCTGGCCACACTGTCCTGGTGCCCAGCCCCCAGCTCTGGAGGGACCCTGG
AGTCCCCGACACACACAGCCACAGCGCCGGGCCAGCCACGGCTCGGAGAAGAAGTCTGCCTGGC
GCAAGATGCGGGTGTACCAGCGTGAAGAGGTCCCCGGCTGCCCCGAGGCCCACGCTGTCTTCCT
AGAGCCTGGCCAGGTAGTGCAAGAGCAGGCCCTGAGCACAGAGGAGCCCAGGGTGGAGCTGTCT
GGGTCCACCCGAGTGAGCCTCGAAGGTCCTGAGCGGAGGCGCTTCTCGGCATCGGAGCTGATGA
CCCGGCTGCACTCTTCTCTGCGCCTGGGGCGGAATTCAGCAGCCCGGGCACTCATCTCTGGGTC
AGGCATCGGAGCAGCCCGGGAAGGGAAAGCATCTGGAATGGAGGCTCGAAGTGTAGAGATGAGC
GGGGACCGGGTGTCGCGGCCAGCCCCTGGTGACTCACGAGAGGGCCATGGCGATTGGTCCGAGC
CCAGGCTAGACACACAGGAAGAGCCGCCTTTGGGGTCCAGGAGCACCAACGAGCGGCGCCAGTC
TCGATTCCTCCTTAACTCCGTCCTCTATCAGGAATACAGCGACGTGGCCAGCGCCCGCGAACTG
CGGCGGCAGCAGCGCGAGGAGGAGGGCCCGGGGGACGAGGCCGAGGGCGCAGAGGAGGGGCCGG
GGCCACCGCGCGCTAACCTCTCCCCCAGCAGCTCCTTCCGGGCGCAGCGCTCGGCGCGAGGCTC
CACCTTCTCGCTGTGGCAGGATATCCCCGACGTACGCGGCAGCGGCGTCCTGGCCACGCTGAGC
CTGCGGGACTGCAAGCTGCAGGAGGCCAAGTTTGAGCTGATCACCTCCGAGGCCTCCTACATCC
ACAGCCTGTCGGTGGCTGTGGGCCATTTCTTAGGCTCTGCCGAGCTGAGCGAGTGTCTGGGGGC
GCAGGACAAACAGTGGCTGTTTTCCAAACTGCCCGAGGTCAAGAGCACCAGCGAGAGGTTCCTG
CAGGACCTGGAGCAGCGGCTGGAGGCAGATGTGCTGCGCTTCAGCGTGTGCGACGTGGTGCTGG
ACCACTGCCCGGCCTTCCGCAGAGTCTACCTGCCCTATGTCACCAACCAGGCCTACCAGGAGCG
CACCTACCAGCGCCTGCTCCTGGAGAACCCCAGGTTCCCTGGCATCCTGGCTCGCCTGGAGGAG
TCTCCTGTGTGCCAGCGTCTGCCCCTTACTTCCTTCCTTATCCTGCCCTTCCAGAGGATCACCC
GCCTCAAGATGTTGGTGGAGAACATCCTGAAGCGGACAGCACAGGGCTCTGAAGACGAAGACAT
GGCCACCAAGGCCTTCAATGCGCTCAAGGAGCTGGTGCAGGAGTGCAATGCTAGTGTACAGTCC
ATGAAGAGGACAGAGGAACTCATCCACCTGAGCAAGAAGATCCACTTTGAGGGCAAGATTTTCC
CGCTGATCTCTCAGGCCCGCTGGCTGGTTCGGCATGGAGAGTTGGTAGAGCTGGCACCACTGCC
TGCAGCACCCCCTGCCAAGCTGAAGCTGTCCAGCAAGGCAGTCTACCTCCACCTCTTCAATGAC
TGCTTGCTGCTCTCTCGGCGGAAGGAGCTAGGGAAGTTTGCCGTTTTCGTCCATGCCAAGATGG
CTGAGCTGCAGGTGCGGGACCTGAGCCTGAAGCTGCAGGGCATCCCCGGCCACGTGTTCCTCCT
CCAGCTCCTCCACGGGCAGCACATGAAGCACCAGTTCCTGCTGCGGGCCCGGACGGAAAGTGAG
AAGCAGCGATGGATCTCAGCCTTGTGCCCCTCCAGCCCCCAGGAGGACAAGGAGGTCATCAGTG
ACGGGGAAGATTGCCCCCAGGTTCAGTGTGTTAGGACATACAAGGCACTGCACCCAGATGAGCT
GACCTTGGAGAAGACTGACATCCTGGCAGTGAGGACCTGGACCAGTGACGGCTGGCTGGAAGGG
GTCCGCCTGGCAGATGGTGAGAAGGGGTGGGTGCCCCAGGCCTATGTGGAAGAGATCAGCAGCC
TCAGCGCCCGCCTCCGAAACCTCCGGGAGAATAAGCGAGTCACAAGTGCCACCAGCAAACTGGG
GGAGGCTCCTGTGTGATGGGCAGCCATGGCCTAGGACCCCACCTCCATGCCTGGCTCCTGGATG
GTCCTGGAGGGGCCTGCAGTGTCTCCATTCCCCAAGCTGCTCCTGCTGGCACTTCGCTTCTGTG
GCCTTGGCATTGAGGGCACAGGCTGGACACAGGAATGGGGGCGCCTCCAGAGGGTCTCTCCGTC
CTCATGCTCCTCAGTGTCCACACTTCAAGGCCAAGGGTAGTTTCTTCCTCTGACATGGGGACCA
TAACAGGTGATCACTGATACCTGGCAAAGACTGGGGCCGTCTCCTTTCTATGTCCTCAATCCTG
CCTGACTCTTGGTCCTTCTGGCAGGGACCTGGCTGGGGAACGTTCTGGTGCTGATGGTGCTGGG
ACCTATATGTATATTTATATATATCTGGGGTCTTGTCTACCACCTCCCCTGGTCAGAGCCCGAG
TGGGTGCTGGTTGCTGTGTCTTGTCTGTAAATAAACTCCTATCATGCCTTTGCTTGGAGTCTGT
GATCCATCTGATGCTGCCCCCACCCCCACAGTCCTATTTTCCCAGCTAAAGACCAGGAGAGTCT
CCGGCTGGCTCCCAACTGGGGCTTTGCATTTCTCTAGAGTTCATCTCTGAGCTGTAAGGGTGAC
CAGGGGACAGGGGGACGATTGTGTATCAGCTAGGCTGCTTTTGGCTGCAAGTAACAAAATATCA
GATACAAATAGGCTTAAACATTAAAGAGATTTGATTAGTTCTT

hide sequence

RefSeq Acc Id:

XM_024926318 ⟹ XP_024782086

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	210,709,315 - 210,723,902 (+)	NCBI
NHGRI_mPanPan1	1	209,957,875 - 209,972,560 (+)	NCBI
Mhudiblu_PPA_v0	1	15,334,564 - 15,346,915 (-)	NCBI
PanPan1.1	1	16,327,135 - 16,339,493 (-)	NCBI

Sequence:

show sequence

ATCTCCCCCAGCCAGCTGGGCAGAGAGAGGGCTTCCCCTGCCGGAACAGCCAAACAGCATCAGC
AGCGGGCCTGGGCCCAGAGAGGGCCAGGTGGGTGGCAGAGCAAAAGAGGAATGGACTGTGGGCC
ACCTGCTACCCTCCAGCCCCACCTGACTGGGCCACCTGGCACTGCCCACCACCCTGTAGCAGTG
TGCCAGCAGGAGAGTCTGTCCTTTGCAGAGCTGCCCGCCCTGAAGCCCCCGAGCCCAGTGTGTC
TGGACCTTTTCCCTGTTGCCCCAGAGGAGCTTCGGGCTCCTGGCAGCCGCTGGTCTCTGGGGAC
CCCTGCCCCTCTCCAAGGGTTGCTATGGCCATCATCCCCAGGAGGCTCAGATACAGAGATCACC
AGCGGGGGGATGCGGCCCAGCAGGGCTGGCAGCTGGCCACACTGTCCTGGTGCCCAGCCCCCAG
CTCTGGAGGGACCCTGGAGTCCCCGACACACACAGCCACAGCGCCGGGCCAGCCACGGCTCGGA
GAAGAAGTCTGCCTGGCGCAAGATGCGGGTGTACCAGCGTGAAGAGGTCCCCGGCTGCCCCGAG
GCCCACGCTGTCTTCCTAGAGCCTGGCCAGGTAGTGCAAGAGCAGGCCCTGAGCACAGAGGAGC
CCAGGGTGGAGCTGTCTGGGTCCACCCGAGTGAGCCTCGAAGGTCCTGAGCGGAGGCGCTTCTC
GGCATCGGAGCTGATGACCCGGCTGCACTCTTCTCTGCGCCTGGGGCGGAATTCAGCAGCCCGG
GCACTCATCTCTGGGTCAGGCATCGGAGCAGCCCGGGAAGGGAAAGCATCTGGAATGGAGGCTC
GAAGTGTAGAGATGAGCGGGGACCGGGTGTCGCGGCCAGCCCCTGGTGACTCACGAGAGGGCCA
TGGCGATTGGTCCGAGCCCAGGCTAGACACACAGGAAGAGCCGCCTTTGGGGTCCAGGAGCACC
AACGAGCGGCGCCAGTCTCGATTCCTCCTTAACTCCGTCCTCTATCAGGAATACAGCGACGTGG
CCAGCGCCCGCGAACTGCGGCGGCAGCAGCGCGAGGAGGAGGGCCCGGGGGACGAGGCCGAGGG
CGCAGAGGAGGGGCCGGGGCCACCGCGCGCTAACCTCTCCCCCAGCAGCTCCTTCCGGGCGCAG
CGCTCGGCGCGAGGCTCCACCTTCTCGCTGTGGCAGGATATCCCCGACGTACGCGGCAGCGGCG
TCCTGGCCACGCTGAGCCTGCGGGACTGCAAGCTGCAGGAGGCCAAGTTTGAGCTGATCACCTC
CGAGGCCTCCTACATCCACAGCCTGTCGGTGGCTGTGGGCCATTTCTTAGGCTCTGCCGAGCTG
AGCGAGTGTCTGGGGGCGCAGGACAAACAGTGGCTGTTTTCCAAACTGCCCGAGGTCAAGAGCA
CCAGCGAGAGGTTCCTGCAGGACCTGGAGCAGCGGCTGGAGGCAGATGTGCTGCGCTTCAGCGT
GTGCGACGTGGTGCTGGACCACTGCCCGGCCTTCCGCAGAGTCTACCTGCCCTATGTCACCAAC
CAGGCCTACCAGGAGCGCACCTACCAGCGCCTGCTCCTGGAGAACCCCAGGTTCCCTGGCATCC
TGGCTCGCCTGGAGGAGTCTCCTGTGTGCCAGCGTCTGCCCCTTACTTCCTTCCTTATCCTGCC
CTTCCAGAGGATCACCCGCCTCAAGATGTTGGTGGAGAACATCCTGAAGCGGACAGCACAGGGC
TCTGAAGACGAAGACATGGCCACCAAGGCCTTCAATGCGCTCAAGGAGCTGGTGCAGGAGTGCA
ATGCTAGTGTACAGTCCATGAAGAGGACAGAGGAACTCATCCACCTGAGCAAGAAGATCCACTT
TGAGGGCAAGATTTTCCCGCTGATCTCTCAGGCCCGCTGGCTGGTTCGGCATGGAGAGTTGGTA
GAGCTGGCACCACTGCCTGCAGCACCCCCTGCCAAGCTGAAGCTGTCCAGCAAGGCAGTCTACC
TCCACCTCTTCAATGACTGCTTGCTGCTCTCTCGGCGGAAGGAGCTAGGGAAGTTTGCCGTTTT
CGTCCATGCCAAGATGGCTGAGCTGCAGGTGCGGGACCTGAGCCTGAAGCTGCAGGGCATCCCC
GGCCACGTGTTCCTCCTCCAGCTCCTCCACGGGCAGCACATGAAGCACCAGTTCCTGCTGCGGG
CCCGGACGGAAAGTGAGAAGCAGCGATGGATCTCAGCCTTGTGCCCCTCCAGCCCCCAGGAGGA
CAAGGAGGTCATCAGTGACGGGGAAGATTGCCCCCAGGTTCAGTGTGTTAGGACATACAAGGCA
CTGCACCCAGATGAGCTGACCTTGGAGAAGACTGACATCCTGGCAGTGAGGACCTGGACCAGTG
ACGGCTGGCTGGAAGGGGTCCGCCTGGCAGATGGTGAGAAGGGGTGGGTGCCCCAGGCCTATGT
GGAAGAGATCAGCAGCCTCAGCGCCCGCCTCCGAAACCTCCGGGAGAATAAGCGAGTCACAAGT
GCCACCAGCAAACTGGGGGAGGCTCCTGTGTGATGGGCAGCCATGGCCTAGGACCCCACCTCCA
TGCCTGGCTCCTGGATGGTCCTGGAGGGGCCTGCAGTGTCTCCATTCCCCAAGCTGCTCCTGCT
GGCACTTCGCTTCTGTGGCCTTGGCATTGAGGGCACAGGCTGGACACAGGAATGGGGGCGCCTC
CAGAGGGTCTCTCCGTCCTCATGCTCCTCAGTGTCCACACTTCAAGGCCAAGGGTAGTTTCTTC
CTCTGACATGGGGACCATAACAGGTGATCACTGATACCTGGCAAAGACTGGGGCCGTCTCCTTT
CTATGTCCTCAATCCTGCCTGACTCTTGGTCCTTCTGGCAGGGACCTGGCTGGGGAACGTTCTG
GTGCTGATGGTGCTGGGACCTATATGTATATTTATATATATCTGGGGTCTTGTCTACCACCTCC
CCTGGTCAGAGCCCGAGTGGGTGCTGGTTGCTGTGTCTTGTCTGTAAATAAACTCCTATCATGC
CTTTGCTTGGAGTCTGTGATCCATCTGATGCTGCCCCCACCCCCACAGTCCTATTTTCCCAGCT
AAAGACCAGGAGAGTCTCCGGCTGGCTCCCAACTGGGGCTTTGCATTTCTCTAGAGTTCATCTC
TGAGCTGTAAGGGTGACCAGGGGACAGGGGGACGATTGTGTATCAGCTAGGCTGCTTTTGGCTG
CAAGTAACAAAATATCAGATACAAATAGGCTTAAACATTAAAGAGATTTGATTAGTTCTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_003806285	(Get FASTA)	NCBI Sequence Viewer
	XP_008949789	(Get FASTA)	NCBI Sequence Viewer
	XP_024782086	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000039296.1

RefSeq Acc Id:	XP_003806285 ⟸ XM_003806237
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CBJ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSR WSLGTPAPLQGLLWPSSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRA SHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPE RRRFSASELMTRLHSSLRLGRNSAARALISGSGIGAAREGKASGMEARSVEMSGDRVSRPAPGD SREGHGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPG DEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKF ELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADV LRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTS FLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLS KKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELG KFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPS SPQEDKEVISDGEDCPQVQCVRTYKALHPDELTLEKTDILAVRTWTSDGWLEGVRLADGEKGWV PQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV hide sequence

RefSeq Acc Id:	XP_008949789 ⟸ XM_008951541
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9CBJ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSR WSLGTPAPLQGLLWPSSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRA SHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPE RRRFSASELMTRLHSSLRLGRNSAARALISGSGIGAAREGKASGMEARSVEMSGDRVSRPAPGD SREGHGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPG DEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKF ELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADV LRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTS FLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLS KKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELG KFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPS SPQEDKEVISDGEDCPQVQCVRTYKALHPDELTLEKTDILAVRTWTSDGWLEGVRLADGEKGWV PQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV hide sequence

RefSeq Acc Id:	XP_024782086 ⟸ XM_024926318
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9CBJ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSR WSLGTPAPLQGLLWPSSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRA SHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPE RRRFSASELMTRLHSSLRLGRNSAARALISGSGIGAAREGKASGMEARSVEMSGDRVSRPAPGD SREGHGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPG DEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKF ELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADV LRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTS FLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLS KKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELG KFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPS SPQEDKEVISDGEDCPQVQCVRTYKALHPDELTLEKTDILAVRTWTSDGWLEGVRLADGEKGWV PQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV hide sequence

Ensembl Acc Id:

ENSPPAP00000039296 ⟸ ENSPPAT00000062206

Protein Domains

DH PH SH3

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000042354	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000062206.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.900.10	UniProtKB/TrEMBL
	2.30.29.30	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	DBL_dom_sf	UniProtKB/TrEMBL
	DH-domain	UniProtKB/TrEMBL
	Ephexin-like	UniProtKB/TrEMBL
	PH-like_dom_sf	UniProtKB/TrEMBL
	PH_domain	UniProtKB/TrEMBL
	PH_ephexin	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
KEGG Report	pps:100985591	UniProtKB/TrEMBL
NCBI Gene	ARHGEF19	ENTREZGENE
PANTHER	GUANINE NUCLEOTIDE EXCHANGE FACTOR	UniProtKB/TrEMBL
	RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 19	UniProtKB/TrEMBL
Pfam	RhoGEF	UniProtKB/TrEMBL
	SH3_2	UniProtKB/TrEMBL
PROSITE	DH_2	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	RhoGEF	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	SSF48065	UniProtKB/TrEMBL
	SSF50044	UniProtKB/TrEMBL
UniProt	A0A2R9CBJ1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-06-11	ARHGEF19	Rho guanine nucleotide exchange factor 19	LOC106633989	uncharacterized LOC106633989	Data merged from RGD:11709066	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar