DPP9 (dipeptidyl peptidase 9) - Rat Genome Database

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Gene: DPP9 (dipeptidyl peptidase 9) Sus scrofa
Analyze
Symbol: DPP9
Name: dipeptidyl peptidase 9
RGD ID: 14232435
Description: ENCODES a protein that exhibits dipeptidyl-peptidase activity (inferred); identical protein binding (inferred); serine-type peptidase activity (inferred); INVOLVED IN pyroptosis (ortholog); ASSOCIATED WITH genetic disease (ortholog); Immunodeficiency 111 (ortholog); interstitial lung disease 2 (ortholog); FOUND IN cell leading edge (ortholog); cytosol (ortholog); microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,134,743 - 74,179,738 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,134,520 - 74,179,740 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell leading edge  (IEA,ISO)
cytosol  (IEA,ISO)
microtubule  (IEA,ISO)
plasma membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DPP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,134,743 - 74,179,738 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,134,520 - 74,179,740 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DPP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,675,227 - 4,723,842 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,674,341 - 4,724,673 (-)EnsemblGRCh38hg38GRCh38
GRCh37194,675,239 - 4,723,854 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,626,236 - 4,674,875 (-)NCBINCBI36Build 36hg18NCBI36
Build 34194,626,236 - 4,674,875NCBI
Celera194,611,917 - 4,660,519 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,435,298 - 4,484,058 (-)NCBIHuRef
CHM1_1194,674,929 - 4,723,546 (-)NCBICHM1_1
T2T-CHM13v2.0194,659,400 - 4,708,159 (-)NCBIT2T-CHM13v2.0
Dpp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,493,674 - 56,525,927 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,493,807 - 56,525,905 (-)EnsemblGRCm39 Ensembl
GRCm381756,186,674 - 56,218,889 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,186,807 - 56,218,905 (-)EnsemblGRCm38mm10GRCm38
MGSCv371756,326,105 - 56,358,312 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,245,956 - 55,278,110 (-)NCBIMGSCv36mm8
MGSCv361755,820,391 - 55,852,545 (-)NCBIMGSCv36mm8
Cytogenetic Map17DNCBI
cM Map1729.2NCBI
Dpp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,098,505 - 1,133,500 (-)NCBIGRCr8
mRatBN7.291,011,347 - 1,046,337 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,011,351 - 1,046,541 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,457,627 - 1,492,012 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,805,144 - 6,839,955 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,762,664 - 5,797,049 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,846,493 - 10,882,560 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,846,596 - 10,882,649 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,838,237 - 9,872,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,464,072 - 7,496,127 (+)NCBICelera
Cytogenetic Map9q11NCBI
Dpp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,269,538 - 4,313,482 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,281,262 - 4,313,674 (+)NCBIChiLan1.0ChiLan1.0
DPP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2209,068,062 - 9,118,264 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,297,791 - 8,347,924 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,693,460 - 3,743,594 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,644,371 - 4,693,789 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,644,371 - 4,693,789 (-)Ensemblpanpan1.1panPan2
DPP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,037,207 - 55,080,478 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,040,614 - 55,077,542 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,761,669 - 54,804,681 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,691,702 - 55,734,682 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,691,660 - 55,732,611 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,753,733 - 54,796,142 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,233,665 - 55,276,631 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,431,646 - 55,474,675 (+)NCBIUU_Cfam_GSD_1.0
Dpp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,078,535 - 215,114,209 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,719,642 - 2,756,248 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,720,574 - 2,756,213 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,394,367 - 4,441,504 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl64,394,750 - 4,440,227 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660813,731,202 - 3,781,719 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dpp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,073,112 - 5,104,504 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,059,997 - 5,104,640 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DPP9
337 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1
Low 10 4 3 4 1 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000026491   ⟹   ENSSSCP00000027818
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,141,726 - 74,175,240 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000030752   ⟹   ENSSSCP00000025200
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,134,743 - 74,179,738 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000038818   ⟹   ENSSSCP00000040762
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,134,750 - 74,179,724 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054763   ⟹   ENSSSCP00000059462
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl274,134,749 - 74,173,985 (+)Ensembl
RefSeq Acc Id: XM_021084042   ⟹   XP_020939701
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1274,134,520 - 74,179,740 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021084043   ⟹   XP_020939702
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1274,134,731 - 74,179,740 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021084044   ⟹   XP_020939703
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1274,134,732 - 74,179,740 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020939701 (Get FASTA)   NCBI Sequence Viewer  
  XP_020939702 (Get FASTA)   NCBI Sequence Viewer  
  XP_020939703 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000025200
  ENSSSCP00000025200.2
  ENSSSCP00000027818.3
  ENSSSCP00000040762
  ENSSSCP00000040762.1
  ENSSSCP00000059462.1
  ENSSSCP00015011992.1
  ENSSSCP00015012118.1
  ENSSSCP00015012287.1
  ENSSSCP00015012349.1
  ENSSSCP00025012014.1
  ENSSSCP00025012039.1
  ENSSSCP00025012069.1
  ENSSSCP00025012106.1
  ENSSSCP00030025742.1
  ENSSSCP00030025747.1
  ENSSSCP00030025759.1
  ENSSSCP00030025778.1
  ENSSSCP00035011672.1
  ENSSSCP00035011674.1
  ENSSSCP00035011678.1
  ENSSSCP00035011691.1
  ENSSSCP00035011695.1
  ENSSSCP00040020967.1
  ENSSSCP00040021046.1
  ENSSSCP00040021170.1
  ENSSSCP00040021216.1
  ENSSSCP00040021289.1
  ENSSSCP00045025225.1
  ENSSSCP00045025536.1
  ENSSSCP00045025823.1
  ENSSSCP00050023810.1
  ENSSSCP00050023812.1
  ENSSSCP00050023814.1
  ENSSSCP00050023816.1
  ENSSSCP00055045502.1
  ENSSSCP00055045578.1
  ENSSSCP00055045669.1
  ENSSSCP00055045804.1
  ENSSSCP00055045889.1
  ENSSSCP00060027627.1
  ENSSSCP00060027631.1
  ENSSSCP00060027637.1
  ENSSSCP00060027644.1
  ENSSSCP00065019724.1
  ENSSSCP00065019729.1
  ENSSSCP00065019747.1
  ENSSSCP00065019755.1
  ENSSSCP00065019763.1
  ENSSSCP00065019803.1
GenBank Protein JAA74188 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_020939701   ⟸   XM_021084042
- Peptide Label: isoform X1
- UniProtKB: A0A8D0N1P9 (UniProtKB/TrEMBL),   M3VH83 (UniProtKB/TrEMBL),   I3LM79 (UniProtKB/TrEMBL),   A0A8D1S9D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020939702   ⟸   XM_021084043
- Peptide Label: isoform X1
- UniProtKB: A0A8D0N1P9 (UniProtKB/TrEMBL),   M3VH83 (UniProtKB/TrEMBL),   I3LM79 (UniProtKB/TrEMBL),   A0A8D1S9D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020939703   ⟸   XM_021084044
- Peptide Label: isoform X2
- UniProtKB: A0A8D1S9D1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000059462   ⟸   ENSSSCT00000054763
RefSeq Acc Id: ENSSSCP00000025200   ⟸   ENSSSCT00000030752
RefSeq Acc Id: ENSSSCP00000027818   ⟸   ENSSSCT00000026491
RefSeq Acc Id: ENSSSCP00000040762   ⟸   ENSSSCT00000038818
Protein Domains
Dipeptidyl peptidase 8 /9 ,N-terminal   Dipeptidylpeptidase IV N-terminal   Peptidase S9 prolyl oligopeptidase catalytic


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000026063 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015022804 UniProtKB/TrEMBL
  ENSSSCG00025020873 UniProtKB/TrEMBL
  ENSSSCG00030040808 UniProtKB/TrEMBL
  ENSSSCG00035022974 UniProtKB/TrEMBL
  ENSSSCG00040037598 UniProtKB/TrEMBL
  ENSSSCG00045021197 UniProtKB/TrEMBL
  ENSSSCG00050041360 UniProtKB/TrEMBL
  ENSSSCG00055028648 UniProtKB/TrEMBL
  ENSSSCG00060047514 UniProtKB/TrEMBL
  ENSSSCG00065033801 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000026491.3 UniProtKB/TrEMBL
  ENSSSCT00000030752 ENTREZGENE
  ENSSSCT00000030752.3 UniProtKB/TrEMBL
  ENSSSCT00000038818 ENTREZGENE
  ENSSSCT00000038818.3 UniProtKB/TrEMBL
  ENSSSCT00000054763.3 UniProtKB/TrEMBL
  ENSSSCT00015030273.1 UniProtKB/TrEMBL
  ENSSSCT00015030616.1 UniProtKB/TrEMBL
  ENSSSCT00015031047.1 UniProtKB/TrEMBL
  ENSSSCT00015031239.1 UniProtKB/TrEMBL
  ENSSSCT00025028396.1 UniProtKB/TrEMBL
  ENSSSCT00025028436.1 UniProtKB/TrEMBL
  ENSSSCT00025028495.1 UniProtKB/TrEMBL
  ENSSSCT00025028581.1 UniProtKB/TrEMBL
  ENSSSCT00030056693.1 UniProtKB/TrEMBL
  ENSSSCT00030056703.1 UniProtKB/TrEMBL
  ENSSSCT00030056728.1 UniProtKB/TrEMBL
  ENSSSCT00030056763.1 UniProtKB/TrEMBL
  ENSSSCT00035030068.1 UniProtKB/TrEMBL
  ENSSSCT00035030072.1 UniProtKB/TrEMBL
  ENSSSCT00035030081.1 UniProtKB/TrEMBL
  ENSSSCT00035030108.1 UniProtKB/TrEMBL
  ENSSSCT00035030118.1 UniProtKB/TrEMBL
  ENSSSCT00040050475.1 UniProtKB/TrEMBL
  ENSSSCT00040050666.1 UniProtKB/TrEMBL
  ENSSSCT00040050986.1 UniProtKB/TrEMBL
  ENSSSCT00040051097.1 UniProtKB/TrEMBL
  ENSSSCT00040051285.1 UniProtKB/TrEMBL
  ENSSSCT00045036266.1 UniProtKB/TrEMBL
  ENSSSCT00045036690.1 UniProtKB/TrEMBL
  ENSSSCT00045037119.1 UniProtKB/TrEMBL
  ENSSSCT00050056073.1 UniProtKB/TrEMBL
  ENSSSCT00050056075.1 UniProtKB/TrEMBL
  ENSSSCT00050056081.1 UniProtKB/TrEMBL
  ENSSSCT00050056084.1 UniProtKB/TrEMBL
  ENSSSCT00055056886.1 UniProtKB/TrEMBL
  ENSSSCT00055056978.1 UniProtKB/TrEMBL
  ENSSSCT00055057094.1 UniProtKB/TrEMBL
  ENSSSCT00055057251.1 UniProtKB/TrEMBL
  ENSSSCT00055057362.1 UniProtKB/TrEMBL
  ENSSSCT00060064506.1 UniProtKB/TrEMBL
  ENSSSCT00060064516.1 UniProtKB/TrEMBL
  ENSSSCT00060064535.1 UniProtKB/TrEMBL
  ENSSSCT00060064550.1 UniProtKB/TrEMBL
  ENSSSCT00065045978.1 UniProtKB/TrEMBL
  ENSSSCT00065045985.1 UniProtKB/TrEMBL
  ENSSSCT00065046010.1 UniProtKB/TrEMBL
  ENSSSCT00065046027.1 UniProtKB/TrEMBL
  ENSSSCT00065046044.1 UniProtKB/TrEMBL
  ENSSSCT00065046117.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
  Dipeptidylpeptidase IV, N-terminal domain UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Dpp_8/9_N UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/TrEMBL
  Peptidase_S9B_N UniProtKB/TrEMBL
NCBI Gene DPP9 ENTREZGENE
PANTHER DIPEPTIDYL PEPTIDASE 9 UniProtKB/TrEMBL
  PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED UniProtKB/TrEMBL
Pfam Dpp_8_9_N UniProtKB/TrEMBL
  DPPIV_N UniProtKB/TrEMBL
  Peptidase_S9 UniProtKB/TrEMBL
Superfamily-SCOP DPP6 N-terminal domain-like UniProtKB/TrEMBL
  SSF53474 UniProtKB/TrEMBL
UniProt A0A287AAC3_PIG UniProtKB/TrEMBL
  A0A480KNR9_PIG UniProtKB/TrEMBL
  A0A8D0N1P9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0RGF8_PIG UniProtKB/TrEMBL
  A0A8D0Z2M3_PIG UniProtKB/TrEMBL
  A0A8D0Z5M0_PIG UniProtKB/TrEMBL
  A0A8D1I0D7_PIG UniProtKB/TrEMBL
  A0A8D1S9D1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1SDJ5_PIG UniProtKB/TrEMBL
  A0A8D1UDF6_PIG UniProtKB/TrEMBL
  A0A8D1VQA6_PIG UniProtKB/TrEMBL
  I3LM79 ENTREZGENE, UniProtKB/TrEMBL
  I3LUL8_PIG UniProtKB/TrEMBL
  M3VH83 ENTREZGENE
UniProt Secondary M3VH83 UniProtKB/TrEMBL
VGNC ID VGNC:87424 ENTREZGENE