LGI4 (leucine rich repeat LGI family member 4) - Rat Genome Database

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Gene: LGI4 (leucine rich repeat LGI family member 4) Sus scrofa
Analyze
Symbol: LGI4
Name: leucine rich repeat LGI family member 4
RGD ID: 14215591
Description: INVOLVED IN adult locomotory behavior (ortholog); glial cell development (ortholog); glial cell proliferation (ortholog); ASSOCIATED WITH arthrogryposis multiplex congenita-1 (ortholog); Brugada syndrome 5 (ortholog); childhood absence epilepsy (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat LGI family member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,655,619 - 44,663,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,655,621 - 44,663,874 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,101,147 - 40,110,225 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LGI4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl644,655,619 - 44,663,234 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1644,655,621 - 44,663,874 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,101,147 - 40,110,225 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LGI4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,124,513 - 35,135,059 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,124,513 - 35,142,451 (-)EnsemblGRCh38hg38GRCh38
GRCh371935,615,417 - 35,625,963 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,307,257 - 40,317,944 (-)NCBINCBI36Build 36hg18NCBI36
Build 341940,307,256 - 40,317,944NCBI
Celera1932,328,853 - 32,339,614 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,123,410 - 32,134,089 (-)NCBIHuRef
CHM1_11935,617,430 - 35,628,191 (-)NCBICHM1_1
T2T-CHM13v2.01937,669,192 - 37,679,738 (-)NCBIT2T-CHM13v2.0
Lgi4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,758,360 - 30,770,347 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,758,767 - 30,770,360 (+)EnsemblGRCm39 Ensembl
GRCm38731,058,909 - 31,070,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl731,059,342 - 31,070,935 (+)EnsemblGRCm38mm10GRCm38
MGSCv37731,844,954 - 31,855,954 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,768,695 - 30,779,695 (+)NCBIMGSCv36mm8
Celera725,627,425 - 25,637,643 (+)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.29NCBI
Lgi4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,422,461 - 95,433,296 (+)NCBIGRCr8
mRatBN7.2186,294,539 - 86,305,909 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,295,074 - 86,304,874 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,715,525 - 91,725,322 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,181,671 - 100,191,468 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,473,801 - 93,483,598 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,491,588 - 89,502,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,491,654 - 89,502,974 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,647,194 - 90,656,996 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,103,249 - 86,113,051 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,181,359 - 86,191,160 (+)NCBI
Celera180,664,083 - 80,673,885 (+)NCBICelera
Cytogenetic Map1q21NCBI
Lgi4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554684,445,155 - 4,453,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554684,441,808 - 4,456,884 (-)NCBIChiLan1.0ChiLan1.0
LGI4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,136,793 - 41,148,652 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,120,123 - 43,131,827 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,070,563 - 32,082,273 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11940,808,853 - 40,827,023 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1940,808,847 - 40,827,024 (-)Ensemblpanpan1.1panPan2
LGI4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11117,443,569 - 117,452,367 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1117,444,941 - 117,452,381 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,843,881 - 116,853,023 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,040,818 - 118,049,960 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,042,211 - 118,049,961 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,603,431 - 117,612,571 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,228,742 - 117,237,902 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,285,232 - 118,294,382 (+)NCBIUU_Cfam_GSD_1.0
Lgi4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934910,514,614 - 10,522,868 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365701,123,298 - 1,132,011 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365701,122,987 - 1,131,270 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LGI4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,057,248 - 30,075,435 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl630,057,917 - 30,067,696 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660737,830,597 - 7,861,538 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lgi4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247948,376,607 - 8,383,642 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247948,358,671 - 8,384,763 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LGI4
209 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 21 1 5 12 12 21 1 4 1

Sequence


Ensembl Acc Id: ENSSSCT00000029901   ⟹   ENSSSCP00000023865
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl644,655,619 - 44,663,234 (-)Ensembl
RefSeq Acc Id: XM_021097157   ⟹   XP_020952816
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1644,655,621 - 44,663,874 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020952816   ⟸   XM_021097157
- UniProtKB: A0A8D1Z5I2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000023865   ⟸   ENSSSCT00000029901
Protein Domains
LRRCT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000025126 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015029354 UniProtKB/TrEMBL
  ENSSSCG00025030169 UniProtKB/TrEMBL
  ENSSSCG00035020532 UniProtKB/TrEMBL
  ENSSSCG00045034969 UniProtKB/TrEMBL
  ENSSSCG00050005950 UniProtKB/TrEMBL
  ENSSSCG00055029812 UniProtKB/TrEMBL
  ENSSSCG00060053488 UniProtKB/TrEMBL
  ENSSSCG00065050823 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000029901 ENTREZGENE
  ENSSSCT00000029901.4 UniProtKB/TrEMBL
  ENSSSCT00015039096.1 UniProtKB/TrEMBL
  ENSSSCT00015039279.1 UniProtKB/TrEMBL
  ENSSSCT00025041133.1 UniProtKB/TrEMBL
  ENSSSCT00035026716.1 UniProtKB/TrEMBL
  ENSSSCT00045060164.1 UniProtKB/TrEMBL
  ENSSSCT00050008088.1 UniProtKB/TrEMBL
  ENSSSCT00055059284.1 UniProtKB/TrEMBL
  ENSSSCT00060072836.1 UniProtKB/TrEMBL
  ENSSSCT00065069617.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  EAR UniProtKB/TrEMBL
  EPTP UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LGI_related UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene LGI4 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT LGI FAMILY MEMBER 4 UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam EPTP UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
PROSITE EAR UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A8D0NB80_PIG UniProtKB/TrEMBL
  A0A8D1VYZ2_PIG UniProtKB/TrEMBL
  A0A8D1Z5I2 ENTREZGENE, UniProtKB/TrEMBL
  I3LIG0_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89701 ENTREZGENE