URGCP (upregulator of cell proliferation) - Rat Genome Database

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Gene: URGCP (upregulator of cell proliferation) Sus scrofa
Analyze
Symbol: URGCP
Name: upregulator of cell proliferation
RGD ID: 14209453
Description: ENCODES a protein that exhibits GTP binding (inferred); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100525140; up-regulator of cell proliferation
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,780,576 - 48,821,582 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,780,521 - 48,817,058 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,469,534 - 53,527,955 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleus  (IEA)

Molecular Function
GTP binding  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
URGCP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,780,576 - 48,821,582 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11848,780,521 - 48,817,058 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,469,534 - 53,527,955 (+)NCBISscrofa10.2Sscrofa10.2susScr3
URGCP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38743,875,913 - 43,926,726 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl743,875,894 - 43,926,411 (-)EnsemblGRCh38hg38GRCh38
GRCh37743,915,512 - 43,966,325 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36743,882,026 - 43,932,521 (-)NCBINCBI36Build 36hg18NCBI36
Celera743,905,366 - 43,955,861 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,800,542 - 43,850,705 (-)NCBIHuRef
CHM1_1743,919,395 - 43,969,911 (-)NCBICHM1_1
T2T-CHM13v2.0744,034,204 - 44,085,026 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2743,955,001 - 44,005,497 (-)NCBI
Urgcp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,663,417 - 5,712,376 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,663,417 - 5,712,376 (-)EnsemblGRCm39 Ensembl
GRCm38115,713,417 - 5,762,376 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,713,417 - 5,762,376 (-)EnsemblGRCm38mm10GRCm38
MGSCv37115,613,420 - 5,662,379 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,614,188 - 5,641,153 (-)NCBIMGSCv36mm8
Celera116,203,912 - 6,252,767 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Urgcp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,808,616 - 84,852,785 (-)NCBIGRCr8
mRatBN7.21480,594,637 - 80,638,972 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,594,633 - 80,619,888 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,996,431 - 85,021,430 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,236,544 - 86,261,539 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,685,868 - 82,710,863 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,957,726 - 86,002,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,957,716 - 85,991,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,649,967 - 86,694,245 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,367,017 - 86,392,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1479,479,557 - 79,504,606 (-)NCBICelera
Cytogenetic Map14q21NCBI
URGCP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2644,523,614 - 44,574,369 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1792,848,544 - 92,899,132 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0740,324,724 - 40,375,428 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1740,408,771 - 40,421,002 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl740,405,063 - 40,421,002 (+)Ensemblpanpan1.1panPan2
LOC610578
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha161,932,794 - 1,983,870 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01614,878,093 - 14,929,211 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,905,538 - 14,929,211 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,509,260 - 14,560,323 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,489,751 - 14,540,971 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in URGCP
1880 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 9 4 3 5 2 23 2 3 3
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000051691   ⟹   ENSSSCP00000048117
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,780,579 - 48,813,901 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000055409   ⟹   ENSSSCP00000048911
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,796,265 - 48,813,901 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000072004   ⟹   ENSSSCP00000062390
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1848,780,576 - 48,821,582 (+)Ensembl
RefSeq Acc Id: XM_021079349   ⟹   XP_020935008
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11848,780,521 - 48,817,058 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020935008 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000048117
  ENSSSCP00000048117.2
  ENSSSCP00000048911.2
  ENSSSCP00000062390.1
  ENSSSCP00040033822.1
  ENSSSCP00045023125.1
Reference Protein Sequences
RefSeq Acc Id: XP_020935008   ⟸   XM_021079349
- UniProtKB: A0A8D1F7Z5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000048117   ⟸   ENSSSCT00000051691
RefSeq Acc Id: ENSSSCP00000048911   ⟸   ENSSSCT00000055409
RefSeq Acc Id: ENSSSCP00000062390   ⟸   ENSSSCT00000072004
Protein Domains
VLIG-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000040519 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00040057784 UniProtKB/TrEMBL
  ENSSSCG00045019508 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000051691 ENTREZGENE
  ENSSSCT00000051691.3 UniProtKB/TrEMBL
  ENSSSCT00000055409.2 UniProtKB/TrEMBL
  ENSSSCT00000072004.1 UniProtKB/TrEMBL
  ENSSSCT00040078426.1 UniProtKB/TrEMBL
  ENSSSCT00045033351.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro G_VLIG_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene LOC100525140 ENTREZGENE
PANTHER UP-REGULATOR OF CELL PROLIFERATION UniProtKB/TrEMBL
  URG4-RELATED UniProtKB/TrEMBL
PROSITE G_VLIG UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287AVG2_PIG UniProtKB/TrEMBL
  A0A287AY87_PIG UniProtKB/TrEMBL
  A0A5G2QF86_PIG UniProtKB/TrEMBL
  A0A8D1F7Z5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:110302 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-22 URGCP  upregulator of cell proliferation  LOC100525140  up-regulator of cell proliferation  Symbol and/or name change 19259463 PROVISIONAL