ANO3 (anoctamin 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: ANO3 (anoctamin 3) Sus scrofa
Analyze
Symbol: ANO3
Name: anoctamin 3
RGD ID: 14174034
Description: ENCODES a protein that exhibits intracellularly calcium-gated chloride channel activity (ortholog); INVOLVED IN calcium activated galactosylceramide scrambling (ortholog); calcium activated phosphatidylcholine scrambling (ortholog); detection of mechanical stimulus (ortholog); ASSOCIATED WITH dystonia (ortholog); dystonia 24 (ortholog); Febrile Seizures (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anoctamin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl233,618,005 - 33,905,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1233,618,740 - 34,048,973 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2236,222,904 - 36,708,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ANO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl233,618,005 - 33,905,069 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1233,618,740 - 34,048,973 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2236,222,904 - 36,708,472 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381126,188,808 - 26,663,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1126,188,842 - 26,663,289 (+)EnsemblGRCh38hg38GRCh38
GRCh371126,210,355 - 26,684,836 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361126,310,254 - 26,641,412 (+)NCBINCBI36Build 36hg18NCBI36
Build 341126,309,546 - 26,641,411NCBI
Celera1126,498,680 - 26,830,111 (+)NCBICelera
Cytogenetic Map11p14.3-p14.2NCBI
HuRef1126,049,842 - 26,381,695 (+)NCBIHuRef
CHM1_11126,352,915 - 26,683,853 (+)NCBICHM1_1
T2T-CHM13v2.01126,329,688 - 26,803,844 (+)NCBIT2T-CHM13v2.0
Ano3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392110,485,546 - 110,780,854 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2110,485,546 - 110,781,268 (-)EnsemblGRCm39 Ensembl
GRCm382110,655,201 - 110,950,391 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2110,655,201 - 110,950,923 (-)EnsemblGRCm38mm10GRCm38
MGSCv372110,498,297 - 110,790,401 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera2111,811,420 - 112,117,515 (-)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.75NCBI
Ano3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83117,690,242 - 118,004,695 (-)NCBIGRCr8
mRatBN7.2397,235,671 - 97,550,090 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl397,238,354 - 97,550,154 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03101,843,516 - 102,203,368 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3101,840,630 - 102,151,489 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03108,441,370 - 108,751,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4396,123,925 - 96,237,157 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1396,018,606 - 96,401,781 (-)NCBI
Celera396,244,306 - 96,609,033 (-)NCBICelera
Cytogenetic Map3q34NCBI
Ano3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554765,813,071 - 6,060,545 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554765,702,888 - 6,060,545 (+)NCBIChiLan1.0ChiLan1.0
ANO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2928,531,536 - 28,865,020 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11128,532,042 - 28,865,368 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01126,287,123 - 26,618,710 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11126,188,895 - 26,519,646 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,047,200 - 26,519,646 (+)Ensemblpanpan1.1panPan2
ANO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12147,046,020 - 47,416,360 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2147,045,978 - 47,410,908 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2146,531,987 - 46,908,223 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02148,182,161 - 48,557,461 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2148,182,107 - 48,553,681 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12147,168,753 - 47,544,204 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02147,335,086 - 47,707,198 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02147,920,278 - 48,293,168 (+)NCBIUU_Cfam_GSD_1.0
Ano3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494737,282,558 - 37,557,680 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365406,439,990 - 6,712,283 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365406,437,362 - 6,712,433 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1138,423,719 - 38,889,088 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl138,422,204 - 38,755,319 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038135,743,996 - 136,210,985 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476616,340,630 - 16,605,724 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476616,340,636 - 16,605,724 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ANO3
12747 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 4 23 3 2 4 14 12 23 3 5 2

Sequence


Ensembl Acc Id: ENSSSCT00000014567   ⟹   ENSSSCP00000014172
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl233,618,740 - 33,987,210 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000049311   ⟹   ENSSSCP00000038425
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl233,618,005 - 33,905,069 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000087757   ⟹   ENSSSCP00000066192
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl233,617,991 - 33,905,069 (-)Ensembl
RefSeq Acc Id: XM_003122910   ⟹   XP_003122958
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1233,618,740 - 33,905,088 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987284   ⟹   XP_013842738
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1233,618,740 - 34,048,973 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987285   ⟹   XP_013842739
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1233,618,740 - 34,048,557 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987290   ⟹   XP_013842744
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1233,618,740 - 33,783,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013987291   ⟹   XP_013842745
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1233,618,740 - 33,784,857 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013842738   ⟸   XM_013987284
- Peptide Label: isoform X2
- UniProtKB: A0A4X1T0C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013842739   ⟸   XM_013987285
- Peptide Label: isoform X1
- UniProtKB: A0A4X1T0C1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003122958   ⟸   XM_003122910
- Peptide Label: isoform X3
- UniProtKB: A0A287A3U4 (UniProtKB/TrEMBL),   A0A4X1SZW6 (UniProtKB/TrEMBL),   A0A4X1T0C1 (UniProtKB/TrEMBL),   A0A8D0M294 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013842745   ⟸   XM_013987291
- Peptide Label: isoform X5
- UniProtKB: A0A8D0Y8M3 (UniProtKB/TrEMBL),   A0A8D1EM90 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013842744   ⟸   XM_013987290
- Peptide Label: isoform X4
- UniProtKB: A0A8D1EM90 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000038425   ⟸   ENSSSCT00000049311
Ensembl Acc Id: ENSSSCP00000014172   ⟸   ENSSSCT00000014567
Ensembl Acc Id: ENSSSCP00000066192   ⟸   ENSSSCT00000087757
Protein Domains
Anoctamin dimerisation   Anoctamin transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000013339 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005043501 UniProtKB/TrEMBL
  ENSSSCG00025070678 UniProtKB/TrEMBL
  ENSSSCG00030070556 UniProtKB/TrEMBL
  ENSSSCG00040043808 UniProtKB/TrEMBL
  ENSSSCG00045004948 UniProtKB/TrEMBL
  ENSSSCG00060011755 UniProtKB/TrEMBL
  ENSSSCG00065017320 UniProtKB/TrEMBL
  ENSSSCG00070005173 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000049311 ENTREZGENE
  ENSSSCT00000049311.3 UniProtKB/TrEMBL
  ENSSSCT00005070420.1 UniProtKB/TrEMBL
  ENSSSCT00005070433.1 UniProtKB/TrEMBL
  ENSSSCT00005070445.1 UniProtKB/TrEMBL
  ENSSSCT00025097107.1 UniProtKB/TrEMBL
  ENSSSCT00025097497.1 UniProtKB/TrEMBL
  ENSSSCT00030098705.1 UniProtKB/TrEMBL
  ENSSSCT00040058702.1 UniProtKB/TrEMBL
  ENSSSCT00040058873.1 UniProtKB/TrEMBL
  ENSSSCT00045008219.1 UniProtKB/TrEMBL
  ENSSSCT00045008222.1 UniProtKB/TrEMBL
  ENSSSCT00060015364.1 UniProtKB/TrEMBL
  ENSSSCT00060015369.1 UniProtKB/TrEMBL
  ENSSSCT00065023020.1 UniProtKB/TrEMBL
  ENSSSCT00070009930.1 UniProtKB/TrEMBL
  ENSSSCT00070009940.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
KEGG Report ssc:100519534 UniProtKB/TrEMBL
NCBI Gene ANO3 ENTREZGENE
PANTHER PTHR12308 UniProtKB/TrEMBL
  PTHR12308:SF16 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
UniProt A0A287A3U4 ENTREZGENE
  A0A4X1SZW6 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1T0C1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0M243_PIG UniProtKB/TrEMBL
  A0A8D0M294 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0M2W7_PIG UniProtKB/TrEMBL
  A0A8D0TA45_PIG UniProtKB/TrEMBL
  A0A8D0Y8M3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EM90 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1GLY5_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287A3U4 UniProtKB/TrEMBL
VGNC ID VGNC:85356 ENTREZGENE