PLEKHA6 (pleckstrin homology domain containing A6) - Rat Genome Database

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Gene: PLEKHA6 (pleckstrin homology domain containing A6) Sus scrofa
Analyze
Symbol: PLEKHA6
Name: pleckstrin homology domain containing A6
RGD ID: 14158993
Description: ASSOCIATED WITH autistic disorder (ortholog); familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family A member 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl964,874,046 - 65,003,248 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1964,876,803 - 65,027,455 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2971,197,101 - 71,363,068 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PLEKHA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl964,874,046 - 65,003,248 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1964,876,803 - 65,027,455 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2971,197,101 - 71,363,068 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381204,218,853 - 204,378,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1204,218,853 - 204,378,214 (-)EnsemblGRCh38hg38GRCh38
GRCh371204,187,981 - 204,329,057 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361202,454,604 - 202,595,667 (-)NCBINCBI36Build 36hg18NCBI36
Build 341200,919,638 - 201,060,701NCBI
Celera1177,323,436 - 177,464,478 (-)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1175,352,932 - 175,494,004 (-)NCBIHuRef
CHM1_11205,611,887 - 205,752,926 (-)NCBICHM1_1
T2T-CHM13v2.01203,483,437 - 203,642,952 (-)NCBIT2T-CHM13v2.0
Plekha6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391133,089,770 - 133,231,173 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1133,091,948 - 133,231,173 (+)EnsemblGRCm39 Ensembl
GRCm381133,162,032 - 133,303,435 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1133,164,210 - 133,303,435 (+)EnsemblGRCm38mm10GRCm38
MGSCv371135,142,674 - 135,200,012 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,073,652 - 135,129,195 (+)NCBIMGSCv36mm8
Celera1135,858,572 - 135,915,993 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map157.91NCBI
Plekha6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81347,166,899 - 47,307,003 (+)NCBIGRCr8
mRatBN7.21344,614,740 - 44,754,951 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1344,615,011 - 44,754,673 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01350,555,454 - 50,582,236 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1350,555,454 - 50,578,720 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01355,608,313 - 55,635,944 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01355,038,342 - 55,151,469 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41346,078,783 - 46,214,550 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1344,948,394 - 45,087,856 (+)NCBICelera
Cytogenetic Map13q13NCBI
Plekha6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540640,066,206 - 40,134,597 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540640,066,260 - 40,200,629 (-)NCBIChiLan1.0ChiLan1.0
PLEKHA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2144,998,411 - 45,156,233 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1144,963,871 - 45,121,490 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01179,821,249 - 179,980,149 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11184,109,553 - 184,268,475 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1184,109,553 - 184,164,492 (-)Ensemblpanpan1.1panPan2
PLEKHA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.138795,368 - 851,823 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl38799,918 - 838,835 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha38890,782 - 1,030,906 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.038790,756 - 911,549 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl38790,758 - 932,400 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.138787,199 - 908,048 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0381,178,604 - 1,299,615 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0381,378,805 - 1,519,290 (-)NCBIUU_Cfam_GSD_1.0
Plekha6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934471,192,620 - 71,329,810 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936567515,854 - 564,448 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936567430,383 - 564,429 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12524,973,035 - 25,130,439 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2525,000,340 - 25,130,573 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605525,733,394 - 25,891,098 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248076,712,883 - 6,784,620 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248076,653,383 - 6,784,287 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLEKHA6
5852 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 5 14 12 23 3 6 1

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021063214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021063223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AEMK02000070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK345286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK351781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU463238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU571280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GFLN01029434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSSCT00000016652   ⟹   ENSSSCP00000016206
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,875,394 - 65,027,293 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000047195   ⟹   ENSSSCP00000041318
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,875,394 - 65,027,293 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000073838   ⟹   ENSSSCP00000065191
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,863,860 - 65,027,223 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000076730   ⟹   ENSSSCP00000062636
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,865,801 - 64,955,238 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078851   ⟹   ENSSSCP00000072821
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,874,046 - 65,003,248 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000086398   ⟹   ENSSSCP00000063823
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,864,169 - 64,913,465 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000087956   ⟹   ENSSSCP00000060726
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,875,394 - 64,916,366 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000088431   ⟹   ENSSSCP00000068688
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,865,490 - 65,026,731 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000088547   ⟹   ENSSSCP00000071833
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl964,863,860 - 65,027,223 (-)Ensembl
RefSeq Acc Id: XM_021063214   ⟹   XP_020918873
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063215   ⟹   XP_020918874
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,803 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063216   ⟹   XP_020918875
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063217   ⟹   XP_020918876
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063218   ⟹   XP_020918877
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063219   ⟹   XP_020918878
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,843 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063220   ⟹   XP_020918879
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063221   ⟹   XP_020918880
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 65,027,455 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063222   ⟹   XP_020918881
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,804 - 64,947,176 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021063223   ⟹   XP_020918882
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1964,876,803 - 64,909,278 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020918874   ⟸   XM_021063215
- Peptide Label: isoform X2
- UniProtKB: A0A8D1J8M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918882   ⟸   XM_021063223
- Peptide Label: isoform X10
- UniProtKB: A0A8D0YK46 (UniProtKB/TrEMBL),   A0A8D1W1H9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918880   ⟸   XM_021063221
- Peptide Label: isoform X8
- UniProtKB: A0A8D1L944 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918879   ⟸   XM_021063220
- Peptide Label: isoform X7
- UniProtKB: A0A8D1L944 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918877   ⟸   XM_021063218
- Peptide Label: isoform X5
- UniProtKB: A0A8D1J711 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918875   ⟸   XM_021063216
- Peptide Label: isoform X3
- UniProtKB: A0A8D1JAE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918876   ⟸   XM_021063217
- Peptide Label: isoform X4
- UniProtKB: A0A8D1JEL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918873   ⟸   XM_021063214
- Peptide Label: isoform X1
- UniProtKB: A0A8D1J8M0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918881   ⟸   XM_021063222
- Peptide Label: isoform X9
- UniProtKB: A0A8D0YK46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020918878   ⟸   XM_021063219
- Peptide Label: isoform X6
- UniProtKB: A0A8D1J126 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000072821   ⟸   ENSSSCT00000078851
Ensembl Acc Id: ENSSSCP00000068688   ⟸   ENSSSCT00000088431
Ensembl Acc Id: ENSSSCP00000071833   ⟸   ENSSSCT00000088547
Ensembl Acc Id: ENSSSCP00000065191   ⟸   ENSSSCT00000073838
Ensembl Acc Id: ENSSSCP00000016206   ⟸   ENSSSCT00000016652
Ensembl Acc Id: ENSSSCP00000062636   ⟸   ENSSSCT00000076730
Ensembl Acc Id: ENSSSCP00000063823   ⟸   ENSSSCT00000086398
Ensembl Acc Id: ENSSSCP00000060726   ⟸   ENSSSCT00000087956
Ensembl Acc Id: ENSSSCP00000041318   ⟸   ENSSSCT00000047195
Protein Domains
PH   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015281 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025012287 UniProtKB/TrEMBL
  ENSSSCG00035003734 UniProtKB/TrEMBL
  ENSSSCG00045035587 UniProtKB/TrEMBL
  ENSSSCG00050076045 UniProtKB/TrEMBL
  ENSSSCG00055025053 UniProtKB/TrEMBL
  ENSSSCG00060055461 UniProtKB/TrEMBL
  ENSSSCG00065060770 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000078851 ENTREZGENE
  ENSSSCT00000078851.2 UniProtKB/TrEMBL
  ENSSSCT00025016842.1 UniProtKB/TrEMBL
  ENSSSCT00035004805.1 UniProtKB/TrEMBL
  ENSSSCT00045061156.1 UniProtKB/TrEMBL
  ENSSSCT00045061348.1 UniProtKB/TrEMBL
  ENSSSCT00045061528.1 UniProtKB/TrEMBL
  ENSSSCT00045061707.1 UniProtKB/TrEMBL
  ENSSSCT00045061844.1 UniProtKB/TrEMBL
  ENSSSCT00045062001.1 UniProtKB/TrEMBL
  ENSSSCT00050104365.1 UniProtKB/TrEMBL
  ENSSSCT00055051097.1 UniProtKB/TrEMBL
  ENSSSCT00060075563.1 UniProtKB/TrEMBL
  ENSSSCT00065083293.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PKHA4/5/6/7_PH UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene PLEKHA6 ENTREZGENE
PANTHER PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 6 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART SM00233 UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  WW domain UniProtKB/TrEMBL
UniProt A0A5G2RE29_PIG UniProtKB/TrEMBL
  A0A8D0YK46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1J126 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1J711 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1J8M0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JAE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1JEL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1L944 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1W1H9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91536 ENTREZGENE