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Gene: DAGLA (diacylglycerol lipase alpha) Sus scrofa

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Symbol:

DAGLA

Name:

diacylglycerol lipase alpha

RGD ID:

14125990

Description:

ENCODES a protein that exhibits hydrolase activity (inferred); monoacylglycerol lipase activity (inferred); INVOLVED IN arachidonate metabolic process (ortholog); PARTICIPATES IN N-cadherin signaling pathway; ASSOCIATED WITH attention deficit hyperactivity disorder (ortholog); autistic disorder (ortholog); autosomal dominant cerebellar ataxia (ortholog); FOUND IN dendrite membrane (inferred); dendritic spine membrane (inferred); early endosome membrane (inferred); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sn1-specific diacylglycerol lipase alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	9,802,013 - 9,863,865 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	9,802,011 - 9,863,808 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	9,351,888 - 9,378,424 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	lung cancer		ISO	DAGLA (Homo sapiens)	9068941	DNA:SNP:rs60507107 (human)	RGD	PMID:25592173 and REF_RGD_ID:151356746

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	attention deficit hyperactivity disorder		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Attention deficit hyperactivity disorder	ClinVar	PMID:28332277
DAGLA	Pig	autistic disorder		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism	ClinVar
DAGLA	Pig	autosomal dominant cerebellar ataxia		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autosomal dominant cerebellar ataxia	ClinVar	PMID:25741868
DAGLA	Pig	genetic disease		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Inborn genetic diseases	ClinVar	PMID:25741868
DAGLA	Pig	Hereditary Paraganglioma-Pheochromocytoma Syndromes		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary Paraganglioma-Pheochromocytoma Syndromes	ClinVar	PMID:22241717 more ...
DAGLA	Pig	intellectual disability		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar
DAGLA	Pig	leukocyte adhesion deficiency 3		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Leukocyte adhesion deficiency 3	ClinVar	PMID:28492532
DAGLA	Pig	NEUROOCULAR SYNDROME 2, PAROXYSMAL TYPE		ISO	DAGLA (Homo sapiens)	8554872	ClinVar more ...	ClinVar	PMID:25741868 more ...
DAGLA	Pig	paraganglioma		ISO	DAGLA (Homo sapiens)	8554872	ClinVar Annotator: match by term: Hereditary Paragangliomas and Pheochromocytomas	ClinVar	PMID:22241717 more ...

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	NEUROOCULAR SYNDROME 2, PAROXYSMAL TYPE		ISO	DAGLA (Homo sapiens)	7240710		OMIM

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	deoxynivalenol	decreases expression	EXP		6480464	deoxynivalenol results in decreased expression of DAGLA mRNA	CTD	PMID:35307453

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	arachidonate metabolic process	involved_in	IBA	MGI:2442032 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	arachidonate metabolic process	acts_upstream_of	ISO	MGI:4438719	9068941	PMID:20147530	MGI	PMID:20147530
DAGLA	Pig	arachidonate metabolic process	involved_in	IEA	UniProtKB:Q6WQJ1 more ...	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	cannabinoid biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	diacylglycerol catabolic process	involved_in	IBA	PANTHER:PTN000486522 and UniProtKB:Q9Y4D2	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	diacylglycerol catabolic process	involved_in	IEA	UniProtKB:Q9Y4D2 and ensembl:ENSP00000257215	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	lipid catabolic process	involved_in	IEA	UniProtKB-KW:KW-0442	150520179		UniProt	GO_REF:0000043
DAGLA	Pig	lipid metabolic process	involved_in	IEA	InterPro:IPR002921	150520179		InterPro	GO_REF:0000002
DAGLA	Pig	lipid metabolic process	involved_in	IEA	UniProtKB-KW:KW-0443	150520179		UniProt	GO_REF:0000043
DAGLA	Pig	monoacylglycerol biosynthetic process	acts_upstream_of_or_within	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	neuroblast proliferation	acts_upstream_of_or_within	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	neurogenesis	acts_upstream_of_or_within	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	regulation of neuroinflammatory response	involved_in	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	retrograde trans-synaptic signaling by endocannabinoid	involved_in	IBA	MGI:2677061 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	retrograde trans-synaptic signaling by endocannabinoid	involved_in	IEA	UniProtKB:Q6WQJ1 more ...	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	cytoplasm	is_active_in	IBA	FB:FBgn0261244 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	dendrite membrane	is_active_in	IBA	MGI:2677061 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	dendrite membrane	located_in	IEA	UniProtKB:Q9Y4D2 and ensembl:ENSP00000257215	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	dendritic spine membrane	located_in	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	early endosome membrane	located_in	IEA	UniProtKB:Q9Y4D2 and ensembl:ENSP00000257215	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	membrane	located_in	IEA	UniProtKB-KW:KW-0472	150520179		UniProt	GO_REF:0000043
DAGLA	Pig	plasma membrane	located_in	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	150520179		UniProt	GO_REF:0000044
DAGLA	Pig	postsynaptic density membrane	located_in	IEA	UniProtKB:Q9Y4D2 and ensembl:ENSP00000257215	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	postsynaptic membrane	is_active_in	IBA	MGI:2677061 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	postsynaptic membrane	is_active_in	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	varicosity	located_in	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	hydrolase activity	enables	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	lipoprotein lipase activity	enables	IBA	FB:FBgn0261244 more ...	150520179		GO_Central	GO_REF:0000033
DAGLA	Pig	monoacylglycerol lipase activity	enables	IEA	UniProtKB:Q6WQJ1 and ensembl:ENSMUSP00000046358	150520179		Ensembl	GO_REF:0000107
DAGLA	Pig	protein binding	enables	ISO	UniProtKB:P11798	9068941	PMID:23502535	UniProt	PMID:23502535
DAGLA	Pig	protein binding	enables	ISO	UniProtKB:O88801 and UniProtKB:Q9Z214	9068941	PMID:17584991	UniProt	PMID:17584991
DAGLA	Pig	protein binding	enables	ISO	UniProtKB:A2RU14 more ...	9068941	PMID:32296183	IntAct	PMID:32296183

Imported Annotations - PID (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
DAGLA	Pig	N-cadherin signaling pathway		ISO	DAGLA (Homo sapiens)	9068941		PID	PID:200209

PMID:22301074	PMID:30032202

DAGLA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	9,802,013 - 9,863,865 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	9,802,011 - 9,863,808 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	9,351,888 - 9,378,424 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DAGLA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	61,680,391 - 61,747,001 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	61,680,391 - 61,747,001 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	61,447,863 - 61,514,473 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	61,204,486 - 61,271,049 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	61,204,485 - 61,271,048	NCBI
Celera	11	58,783,359 - 58,849,887 (+)	NCBI		Celera
Cytogenetic Map	11	q12.2	NCBI
HuRef	11	57,776,095 - 57,842,730 (+)	NCBI		HuRef
CHM1_1	11	61,331,166 - 61,397,733 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	61,669,309 - 61,735,921 (+)	NCBI		T2T-CHM13v2.0

Dagla
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,222,629 - 10,282,323 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,222,629 - 10,282,241 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,245,265 - 10,304,877 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,245,265 - 10,304,877 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,319,755 - 10,379,367 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,314,709 - 10,338,633 (-)	NCBI		MGSCv36	mm8
Celera	19	10,941,259 - 11,000,633 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	6.55	NCBI

Dagla
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	216,315,515 - 216,372,219 (-)	NCBI		GRCr8
mRatBN7.2	1	206,890,635 - 206,947,332 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	206,890,638 - 206,947,232 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,269,042 - 215,325,636 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,324,194 - 222,380,864 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,019,202 - 215,075,872 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,297,013 - 226,353,712 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,297,016 - 226,353,611 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,241,960 - 233,298,558 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	212,733,659 - 212,790,254 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	212,892,088 - 212,948,684 (-)	NCBI
Celera	1	204,387,304 - 204,443,897 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Dagla
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	5,952,087 - 5,974,172 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	5,952,134 - 5,997,280 (-)	NCBI	ChiLan1.0	ChiLan1.0

DAGLA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	62,848,284 - 62,915,337 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	63,891,908 - 63,958,984 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	56,979,558 - 57,046,589 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	60,378,493 - 60,407,095 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	60,378,493 - 60,407,095 (+)	Ensembl	panpan1.1		panPan2

DAGLA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	54,727,932 - 54,754,077 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	54,730,454 - 54,752,646 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,302,775 - 53,364,054 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	55,774,807 - 55,836,307 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	55,777,324 - 55,799,491 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	54,835,389 - 54,896,860 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	54,459,494 - 54,518,273 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,337,327 - 55,398,846 (-)	NCBI		UU_Cfam_GSD_1.0

Dagla
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	11,257,463 - 11,316,909 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	1,371,262 - 1,430,801 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936581	1,371,292 - 1,430,699 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DAGLA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	12,110,100 - 12,175,935 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	12,108,810 - 12,136,105 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	109,483,813 - 109,550,081 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dagla
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624926	638,259 - 656,953 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624926	638,432 - 680,726 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in DAGLA
1900 total Variants

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3


RefSeq Transcripts	XM_021082924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU914494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01016660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000014297 ⟹ ENSSSCP00000013911

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	9,802,015 - 9,863,781 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000055292 ⟹ ENSSSCP00000048659

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	9,802,013 - 9,863,865 (-)	Ensembl

RefSeq Acc Id:

XM_021082924 ⟹ XP_020938583

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	9,802,011 - 9,863,808 (-)	NCBI

Sequence:

show sequence

GCCCTGCGGAAGCGGCGTTAGTGAATCGGGGCCTTGGGGAGCCCAGGATGGAGGTGGCGGTCGCGGCGGCGGCGGCGGGCCGAGCCCTGCGGCGGGCTGGAGGAGGTGAGCGCCAGGCCCGCTGAGCC
TCCGCAGAGCTGCCAGCCATGCCCGGGATCGTGGTGTTCCGGCGGCGCTGGTCTGTGGGCAGCGATGACCTCGTCCTGCCGGCCATCTTCCTCTTCCTCCTGCACACCACCTGGTTTGTGATCCTGTC
CGTGGTGCTCTTCGGCCTGGTCTACAACCCGAACGAGGCCTGCTCCCTGAACCTGGTGGACCACGGCCGCGGCTACCTGGGCATTTTGCTGAGCTGCATGATCGCCGAGATGGCCATCATCTGGCTGA
GCATGCGCGGCGGCATCCTCTACACTGAGCCCCGCGAATCCATGCAGTACGTGCTCTACGTGCGCCTGGCCATCCTGGTGATCGAGTTCATCTACGCCATAGTGGGCATCGTCTGGCTCACTCAGTAC
TACACCTCCTGCAACGACCTCACTGCCAAGAACGTCACTCTCGGGATGGTCGTCTGCAACTGGGTGGTCATCCTGAGCGTCTGCATCACCGTCCTCTGCGTCTTCGACCCCACGGGCCGCACCTTCGT
CAAGCTGAGGGCCACCAAGCGGAGGCAGCGCAACCTGCGCACCTACAACCTGCGGCACCGCTTAGAAGAGGGTCAGGCCACCAGCTGGTCACGCCGGCTCAAAGTGTTCCTCTGCTGCACTCGGACAA
AGGACTCGCAGTCAGACGCCTACTCGGAAATCGCCTACCTCTTCGCCGAGTTTTTCCGAGACCTCGACATCGTGCCATCCGACATCATCGCTGGCCTGGTGCTGCTCCGGCAGCGGCAGCGGGCCAAG
CGCAACGCCGTGCTGGATGAGGCCAACAACGACATCTTGGCCTTTCTGTCTGGGATGCCGGTGACCAGAAACACCAAGTACCTCGACCTCAAGAACTCGCAAGAGATGCTCCGCTACAAGGAGGTCTG
CTACTACATGCTCTTCGCCCTGGCCGCCTACGGCTGGCCCATGTACCTGATGCGCAAGCCGGCCTGCGGCCTCTGCCAGCTGGCCCGGTCCTGCTCGTGCTGCCTGTGCCCCGCACGGCCCCGGTTTG
CCCCTGGAGTGACCATCGAGGAAGACAACTGCTGTGGCTGCAACGCCATTGCCATCCGGCGCCACTTCCTGGACGAGAACATGACCGCGGTGGACATCGTCTACACCTCCTGCCACGACGCGGTCTAC
GAAACCCCCTTCTACGTGGCAGTGGACCACGACAAGAAGAAGGTAGTGATCAGTATCCGGGGAACCCTGTCCCCCAAGGATGCCCTGACGGACCTGACCGGTGACGCTGAGCGCCTCCCGGTGGAGGG
CCACCACGGCACCTGGCTGGGACACAAGGGCATGGTCCTCTCGGCGGAGTACATCAAGAAGAAGCTGGAGCAGGAGATGGTCCTGTCCCAGGCCTTCGGGCGAGACCTGGGCCGCGGAACCAAACACT
ACGGCCTGATCGTGGTGGGCCACTCCCTGGGGGCAGGCACCGCTGCCATCCTCTCCTTCCTCCTGCGTCCCCAGTACCCGACCCTCAAGTGCTTTGCGTACTCCCCGCCAGGGGGCCTGCTGAGTGAG
GACGCCATGGAGTACTCTAAGGAGTTTGTGACGGCTGTGGTTCTGGGCAAAGACCTTGTCCCCAGGATCGGCCTGTCCCAGCTGGAAGGCTTCCGCAGGCAGCTCCTGGACGTCCTGCAGCGAAGCAC
CAAGCCCAAATGGCGAATCATCGTGGGGGCCACCAAATGCATCCCCAAGTCAGAGCTGCCCGAGGAGGTGGAGGTGACCACCCTGGCCAGCACGCGGCTCTGGACCCACCCCAGCGACCTGACCATCG
CCTTGTCGGCCAGCACCCCTCTCTACCCGCCTGGCCGCATCATCCACGTGGTCCACAACCACCCAGCGGAGCAGTGCTGCTGCTGCGAGCAGGAGGAGCCCACCTACTTTGCCATCTGGGGCGACAAC
AAGGCCTTCAACGAGGTGATCATCTCGCCGGCCATGCTGCACGAGCACCTGCCCTATGTGGTCATGGAAGGGCTCCACAAGGTGCTGGAGAACTACAACAAAGGGAAGACAGCCCTCCTCTCTGCTGC
GAAGGTCATGGTGAGCCCCACCGAGGTGGACCTGACTCCTGAGCTCATCTTCCAGCAGCAGCCGCTGCCCACGGGGCCCCCCGTACCCGCCGGCCTGGCCCTGGACCTGCCCCCCGCAGACCACCGAA
ACAGCAGCGTCAGGAGCAAGTCCCAGTCTGAGATGAGCCTGGAGGGCTTCTCGGAGGGGCGGCTGCTGTCCCCGGTGGCCGCGGCCTCGGCGGCCCGCCAGGACCCAGTGGAGCTGCTGCTGCTGTCC
ACCCAGGAGCGGCTGGCGGCGGAGCTGCAGGCGCGGCGGGCGCCGCTGGCCACCATGGAGAGCCTCTCGGACACCGAGTCGCTGTACAGCTTCGACTCGCGCCGCTCCTCGGGCTTCCGCAGCATCCG
CGGCTCGCCCAGCCTCCATGCGGTGCTGGAGCGCGACGAGGGCCACCTCTTCTACATCGACCCCGCCATCCCCGAGGAGAACCCGTCCCTGAGCTCGCGCACCGAGCTGCTGGCGGCCGACAGCCTGT
CCAAGCACTCGCAGGACACGCAGCCCCTGGAGGCCGCCCTGGGCAGCGGGGGCGTCACCCCCGAGCGGCCCCCCAGCGCAGCGGCCCACGAAGAGCCGGAAGAAGAGGGGGGCGGGCCGGCCCCCCGC
AGCGCAGAGCTGGCGCTGCACGACGGGCGTCTGGGGGACTCGCCCAGCCCTCAGGTGCTGGAGTTCGCCGAGTTCATCGACAGCCTCTTCAACCTGGACAGCAAGAGCAGCTCCTTCCAGGACCTCTA
CTGCATGGTGGTGCCCGAGAGCCCCACCAGCGACTACGCCGAGGGCCCCAAGTCCCCCAGCCAGCAAGAGATCCTGCTCCGCGCCCAGTTCGAGCCCAACCTGGTGCCCAAGCCCCCGAGGCTCTTTG
CCGGCTCGGCCGACCCCTCCTCGGGCATCTCGCTGTCACCCTCCTTCCCGCTCAGCTCCTCAGGCGAGCTCATGGACCTGACGCCGACGGGCCTCAGCAGCCAGGAGTGCCTGGCGGTGGACAAGATC
CGGACTTCTACCCCCACCGGCCACGGGGCCAGCCCCNCCAAGCAGGATGACTTGGTCATCTCGGCACGCTAGCACCCCAGGAGCGGCTGCCAGCTGAGGCCCAGGCCAAAGCCGGTGGCTCCTGCGTC
TCCTGGTGACTGCCCCTCACCCCCGCCCCGGGGCTGGGCGGCTTTGAGGAGAGGGCCACCTGTCCCCGCCCCGCACCGGGGTTGAGGGGGGGGCAGGGTAGCCTCAGGCATTGGGTACTGCTGCTGAG
CTGGGGGTCCGCATCCCTACCTCAGCTTAGGACCCCCAGAGCCAAGGCAGCTGGGATCTAGGCCTCCCAGAGTGGGAATGAGGGGGAGGCGTGTGGAGCAAGGAGGAGCCCGGGGCAGCCCGCCAGAG
GGGTCCCCTCAGCCTGACTGCCCCCCACAGGGACATCCTGGCACTCCCTGTTCCAGGACAGGCCATGGGTATGCCGACTCCCCATCACTGCCCTCTGGCTGTGCTGCCAGGGCCGGGATGGAGAGCAG
CAGCCCCCTCCCCACGTACTCTCATCTGTGGTCCAGGTCTGGCATCTGCCCTGGCCACCCCCAGATCTGGTGCCTGCTGGCCAGCCCCCTGGGGGGACCCTCCCTCCGCCCCCCACCGAGGTGGCCCG
CAGTGCTGTGTATGTTTACAGAAGCTGCTGGGCTGGGCTCAGGATCTGTCCTGGGCTCACAAGCCCCCCACCCTGCAATCATGTGTTCAGTAGCCCCTCTCTGAGCAGGTAGGGGCCAGAGTCCACGG
GGCCCAAGGCAGGACCACCCCTTCTCTGCTTGCTCTCCCTCATGCTGATCTCTCTGTCCATGGGTCCTGGGTACCCAGGCCTGCCCCACTGCCCATTAGTTACTTCCGGGCCTGCCTTCTACTCCCAG
GGACCCTGGCCACTCAAAGGGTGGAGGGCACAGGTGTGACCACCCCTGGCTGCAGAGTCAGTGCCCTGGGAGGAAAGAGGGTCCCACCAAACCCCTTTTTAATCACCTTCCCCCAGGCCAAGGCACCC
TGGGCCCTGGGATCTGAAACCAAACACGCCTCCACTCCCTTCGGCTCCCGCTTCTCGCTGGCCTGGGCTCTCTCCTGGGAACGGGGCCCTCTGCCCTCCCACCCCTGCTGGCAGGAAGCAGGGCCAAG
GGTGGGGTATTGTGGGACCCGGCTAGAGACCCTGGAGGGGCCAGGGGCCCCGAGGCCTCCACAGCCCCTGCTTGAGGGGTTCCTTTGCTGCTGGGTTGGGGGAGCAGTGGCAGGGGAGGCCCTGCCTG
TCCCCAGAGGCAGAGCGAGGAGGCCGTGCATGTGGCGCGGGCGTGTGTGTGCATGTGCATGAGCGTGCGCCATCCCGAGGACGCGGCTGCGGGGCGCCCTCCCCGCCCTGCCTGCCTGCCGCCCCCCA
GCCTGCCGAGAAAACAGGCGGCCAGCATGCGGCGGGGACCAGGGGACAAGCCCGTCCCTTTCCCCTCGTCTCGCCTGCTGCTCCGGCCCCCGGTTTGGAAAACTGGTGTGTGCCCAGGCGTTGACCGC
CCGCTTGTGCCTTCGTCTCCTCGGAGGCATGGTCCCCCCCACTCCGGGCCTGCCCAGGCTCCCCTGACCAAGACCCCCATCTCATGATCACTGGTGTCTGGGAGCCCTGCCCACCCTGACAGACAGGG
ACAGAGACCTGGGAGCTGGGCCTCCCTCACCCTCTGACTCCCACCCCCTCATCAGGTTCCATCAGGCACCTGCCCCTGCCGGGGGCCCTACACAGAAACGGGATGGAATCAGTGGCTCTTAGAGTTAA
AAAAAAAAAAAAAGACAAATCATAAATCAGAATAAAGTTCCAATAAGCACCCCAGCCAATAGCAGGGAGATTTAGGGTCCGGCCTTTTAATTCCTCCTCCACCAGGGTGGGCCTGGGACTTCTGAGGG
GGCGTGGTGCCCGCCCATCCCAGGACTGAGCCATCAGGGACAGACCCCCCCACCCCCAAGGCTGCAGCCACACAGGGTCACAGGCTTGGGGCTGGGGCAGGCTCGGACTCAGCCCTGGTCGCCCCCGG
GTCAGCCCACCCCTCACCCGCACCCCCCCTCGCCCCCGCCCCCGCCCCTGGAGGATGGGCCTGCTGCGTGTCTCCCCCTTCCTCCGCACACCACACGTGGGGGGGTCTGAGCCACCCCCCTCAGCCCA
GCTCGGCTCAGACCGACCCCCACTCTGTCCCCCAGACCCGCAGCACAAGGTCTCCTGGCCATGCACTGGCCTGTCCCCCCAGAGGCCTGGATGACCTCCATATGCAATCGGCAGTGAGCAGCTGGGCC
CCACAGACACTCACGCACTGTACGTGCCATGCTCCCCTGACTTTTTTTGTACTTAATGTATGAAAGATCCAAACTAATATTGCTGTAAAAAGGAGAGACAAATTAATATAGCTTATTCTATAAATATA
TCTGTATATACGGGTTTCTGTATATTGTATAGAGCTGTGTATAAACTGGATGTAGAAGCA

hide sequence


Protein RefSeqs	XP_020938583	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000013911.4
	ENSSSCP00000048659
	ENSSSCP00000048659.1
	ENSSSCP00025021621.1
	ENSSSCP00030037906.1
	ENSSSCP00030037945.1
	ENSSSCP00035027815.1
	ENSSSCP00035027820.1
	ENSSSCP00045040441.1
	ENSSSCP00045040546.1
	ENSSSCP00050022994.1
	ENSSSCP00050023002.1
	ENSSSCP00055015639.1
	ENSSSCP00055015704.1
	ENSSSCP00065040300.1
	ENSSSCP00065040317.1

RefSeq Acc Id:

XP_020938583 ⟸ XM_021082924

- UniProtKB:

A0A480KPI4 (UniProtKB/TrEMBL), A0A8D1TFA4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPNEACSLNLVDHGRGYLGILLSCMIAEMAIIWLSMRGGILYTEPRESMQYVLYVRLAILVIEFIYAIVGIVWLTQYYTSCND
LTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQRAKRNAVLD
EANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLDENMTAVDIVYTSCHDAVYETPFYV
AVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYS
KEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEV
IISPAMLHEHLPYVVMEGLHKVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPVPAGLALDLPPADHRNSSVRSKSQSEMSLEGFSEGRLLSPVAAASAARQDPVELLLLSTQERLA
AELQARRAPLATMESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAAHEEPEEEGGGPAPRSAELAL
HDGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAVDKIRTSTPT
GHGASPXKQDDLVISAR

hide sequence

Ensembl Acc Id:

ENSSSCP00000048659 ⟸ ENSSSCT00000055292

Ensembl Acc Id:

ENSSSCP00000013911 ⟸ ENSSSCT00000014297

Protein Domains

Fungal lipase-type

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000013079	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025037225	UniProtKB/TrEMBL
	ENSSSCG00030059093	UniProtKB/TrEMBL
	ENSSSCG00035051593	UniProtKB/TrEMBL
	ENSSSCG00045033807	UniProtKB/TrEMBL
	ENSSSCG00050040291	UniProtKB/TrEMBL
	ENSSSCG00055010135	UniProtKB/TrEMBL
	ENSSSCG00065067111	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000014297.4	UniProtKB/TrEMBL
	ENSSSCT00000055292	ENTREZGENE
	ENSSSCT00000055292.2	UniProtKB/TrEMBL
	ENSSSCT00025050661.1	UniProtKB/TrEMBL
	ENSSSCT00030082516.1	UniProtKB/TrEMBL
	ENSSSCT00030082599.1	UniProtKB/TrEMBL
	ENSSSCT00035068714.1	UniProtKB/TrEMBL
	ENSSSCT00035068725.1	UniProtKB/TrEMBL
	ENSSSCT00045057849.1	UniProtKB/TrEMBL
	ENSSSCT00045058013.1	UniProtKB/TrEMBL
	ENSSSCT00050054482.1	UniProtKB/TrEMBL
	ENSSSCT00050054492.1	UniProtKB/TrEMBL
	ENSSSCT00055019818.1	UniProtKB/TrEMBL
	ENSSSCT00055019897.1	UniProtKB/TrEMBL
	ENSSSCT00065092100.1	UniProtKB/TrEMBL
	ENSSSCT00065092138.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	DAG_Lipase-Related	UniProtKB/TrEMBL
	Fungal_lipase-like	UniProtKB/TrEMBL
NCBI Gene	DAGLA	ENTREZGENE
PANTHER	DIACYLGLYCEROL LIPASE HOMOLOG-RELATED	UniProtKB/TrEMBL
	DIACYLGLYCEROL LIPASE-ALPHA	UniProtKB/TrEMBL
Pfam	Lipase_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	A0A287AXN8_PIG	UniProtKB/TrEMBL
	A0A480KPI4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0RVG6_PIG	UniProtKB/TrEMBL
	A0A8D1CXJ8_PIG	UniProtKB/TrEMBL
	A0A8D1MHP4_PIG	UniProtKB/TrEMBL
	A0A8D1TFA4	ENTREZGENE, UniProtKB/TrEMBL
	F1RKR2_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:87152	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)