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Gene: SLC25A31 (solute carrier family 25 member 31) Sus scrofa

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Symbol:

SLC25A31

Name:

solute carrier family 25 member 31

RGD ID:

14111244

Description:

ENCODES a protein that exhibits antiporter activity (inferred); ATP:ADP antiporter activity (inferred); INVOLVED IN male meiosis I (inferred); mitochondrial ADP transmembrane transport (inferred); mitochondrial ATP transmembrane transport (inferred); ASSOCIATED WITH neuronal ceroid lipofuscinosis 7 (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrial permeability transition pore complex (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ADP/ATP translocase 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	97,095,517 - 97,120,250 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	97,095,503 - 97,120,940 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	103,958,654 - 103,983,983 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

neuronal ceroid lipofuscinosis 7 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

male meiosis I (IEA)

mitochondrial ADP transmembrane transport (IEA)

mitochondrial ATP transmembrane transport (IEA)

negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (IBA)

regulation of mitochondrial membrane permeability (IEA)

spermatogenesis (IEA)

Cellular Component

membrane (IEA)

mitochondrial inner membrane (IEA)

mitochondrial permeability transition pore complex (IEA)

mitochondrion (IEA)

Molecular Function

antiporter activity (IEA)

ATP:ADP antiporter activity (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SLC25A31
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	97,095,517 - 97,120,250 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	97,095,503 - 97,120,940 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	103,958,654 - 103,983,983 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC25A31
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	127,730,400 - 127,774,292 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	127,730,400 - 127,774,292 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	128,651,555 - 128,695,447 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	128,871,024 - 128,914,897 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	4	126,030,533 - 126,074,415 (+)	NCBI		Celera
Cytogenetic Map	4	q28.1	NCBI
HuRef	4	124,379,238 - 124,423,119 (+)	NCBI		HuRef
CHM1_1	4	128,628,022 - 128,671,905 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	131,033,425 - 131,077,300 (+)	NCBI		T2T-CHM13v2.0

Slc25a31
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	40,663,301 - 40,680,525 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	40,663,285 - 40,680,527 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	40,708,871 - 40,726,094 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	40,708,855 - 40,726,096 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	40,512,793 - 40,530,016 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	40,805,481 - 40,822,142 (+)	NCBI		MGSCv36	mm8
Celera	3	40,438,962 - 40,456,166 (+)	NCBI		Celera
Cytogenetic Map	3	B	NCBI
cM Map	3	19.5	NCBI

Slc25a31
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	125,623,331 - 125,639,155 (+)	NCBI		GRCr8
mRatBN7.2	2	123,695,387 - 123,711,275 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	123,695,408 - 123,710,795 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	127,538,323 - 127,554,276 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	127,538,659 - 127,554,307 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	147,143,351 - 147,159,292 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	127,652,328 - 127,667,553 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	118,603,774 - 118,619,883 (+)	NCBI		Celera
Cytogenetic Map	2	q26	NCBI

Slc25a31
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955428	13,648,699 - 13,667,133 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955428	13,648,753 - 13,667,133 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC25A31
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	125,493,722 - 125,537,861 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	125,759,835 - 125,803,989 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	119,894,274 - 119,938,168 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	131,200,402 - 131,244,034 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	131,200,402 - 131,243,952 (+)	Ensembl	panpan1.1		panPan2

SLC25A31
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	13,164,134 - 13,190,346 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	13,164,245 - 13,276,496 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	13,352,774 - 13,378,984 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	13,254,200 - 13,280,433 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	13,254,307 - 13,280,283 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	13,227,346 - 13,253,552 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	13,512,863 - 13,539,135 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	13,974,826 - 14,001,040 (-)	NCBI		UU_Cfam_GSD_1.0

Slc25a31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405301	61,628,301 - 61,652,793 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936642	2,921,852 - 3,025,083 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936642	2,921,629 - 2,945,577 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC25A31
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	7	74,857,296 - 74,892,873 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	7	74,857,818 - 74,892,156 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	53,991,729 - 54,027,399 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc25a31
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624777	8,676,083 - 8,700,281 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624777	8,676,933 - 8,700,198 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SLC25A31
534 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	ectoderm	endocrine system	mesenchyme	nervous system	reproductive system
1	3	1	1	3	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003129207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000009944 ⟹ ENSSSCP00000009688

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	8	97,095,517 - 97,120,250 (-)	Ensembl

RefSeq Acc Id:

XM_003129207 ⟹ XP_003129255

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	8	97,095,503 - 97,120,940 (-)	NCBI

Sequence:

show sequence

CCATATGTCACCCTAAAAGGCAAAAAACAAAAACAAAAAACAGACACTTCTTTGTGGTCTTCAG
TGTTGTTAAGAGTAAAAGGGGCTCCTAAATTCAAAGTTTGTGAACCACTCTTCCAGAACAGGCG
TTGGTCATCAACCCTCCACATTAGAATTACCTGGTGAATTGACATTCAAATATGGACACCTGAA
TTCCCTTCTAAAGATTCTGATTTAATGGTCAAGGCCTCAGCCCAAGCATTAAACAAAACAAAAC
ATTGTTCCCGCCCTCATCCCCCTTTGTGCATTCTGAGTTGAACACCACTGCTCTGTATAGAATT
ACCAATTTAAATAAAATAAAGGGGAAAGAGGAACATGTTAGTGTTATAGGGGTGCGATCAGTAA
ACAGTGCAATCAGTGAGACAGTGACTAGATAAGCGACTCCTGCTAAATTAAATGAGCAGAAATG
GCAACAATTTCTAAGGTGGAAGGATTACTCTGGGAACTGAAAGTAAACTCGATTAATCCTACAC
AGTTGGCTTACTGCTCTTAGTTTTGACTGCTAAATATCCTTATACAGAACTGGCTCTCCCAGAT
CCCCTTTCACACCTTCCCAGGCCAGAATCCACGGCGACGCTTGCCTGCTCGCCACAACCAAAGC
CTGGCACCTACAGCTGTCAAGACACCGCCACGTGGAGGAGCCACGTGTCGTGGGTCACGTGGCC
TGTGCCAGGTGGAGGGAGGCGGTTGGAGGCGCCTGCGCAACTCCCTGCCTACTGGCACGCTGAT
CTCCCGTTCTGAGCGCCGCTTTCCCGCCAGGAAAACACTGGAGCGGTTTTCGGCTTCTTTTCGT
TCTCTCCCGTGCTGGTTTTGAGGTGCTGTAGCTTGTTTTTACGTCCATCGTCCCACCATGCAGC
GTGAATCTCCGAAAAAGAAGCAGGAGAAGAAGGCGGAGAAACGGATTTTTGACGCCGGGTCCTT
TGGGAAGGACTTGCTCGCAGGTGGGGTGGCAGCGGCTGTGTCCAAGACGGCGGTGGCGCCCATC
GAGCGGGTGAAGTTGCTGCTGCAAGTGCAGGCGTCGTCCAAGCAGATCAGCCCCGAGGCGCAGT
ACAAAGGCATAGTGGACTGTCTGGTGCGGATTCCGCGAGAGCAGGGTTTCTTCAGTTATTGGCG
TGGCAATTTGGCAAATGTTATCCGGTATTTTCCAACACAAGCTCTAAACTTTGCTTTTAAAGAC
AAATATAAACAACTTTTCATGTCCGGAGTTAATAAAGAAAAACAGTTCTGGAGGTGGTTTTTGG
CAAATCTGGCTGCTGGTGGAGCTGCTGGGGCAACATCCTTATGTGTAGTATATCCACTAGATTT
TGCTCGAACCCGATTAGGTGCTGATATTGGAAAAGGTCCTGAAGAGCGACAATTCAAGGGTTTA
GGTGACTGTATTGTGAAAATAGCAAAGTCAGATGGAATTGTTGGTTTATACCAAGGGTTTGGTG
TTTCAGTTCAAGGCATCATTGTATACCGAGCCTCATATTTTGGAGCTTATGACACAGTTAAGGG
CTTGTTACCAAAACCAAAGGAAACCCCTTTTCTTATCTCCTTTTTCATTGCTCAAGTTGTGACT
ACATGCTCTGGAATACTGTCTTATCCGTTTGACACAGTTAGAAGACGCATGATGATGCAGAGTG
GTGAGACTGAACGGCAATATAAAGGAACTTTAGACTGCTTTGTAAAGATATACCAACACGAGGG
AATCAGTGCCTTTTTTCGAGGTGCCTTCTCAAATATCCTTCGTGGTACAGGGGGTGCTTTGGTG
TTGGTGTTATATGATAAAATTAAAGACTTCCTTAATATTGATATTGGAAGTAGTTCATCAGGAG
ATTAATTTGAGAAATGCATATAGTTAACTTTTAAACATACAATTACATAGCTGCCATTTCTGTA
CATTTTGAGAGTGTGTTATTTTTGTCAGTATTTTCTTAAAGTGCTAATGCTGTGATAAAGCATA
GGCTTTTTTCAAGGATTTAAACACTAAAAATCAGATAAATGTGGTTTCCTTCCTCCTTAGACTC
AAACTATTTTAATGACACATTTTACTTATTATAAGAGGTACATGTTATTCTATTAAATTTTTTC
TTTTGTGATAAAAATTAAAATATATAATCTGAAATCTAAGAAATGGAACATCTTTTAAAATGGT
ATTCTTTTAATATAATTGTCTCCCCATCTTTTAAAATCATATGATATGACAAATATTTCTTAAA
AGCTTATTAGGGGATGTCATCATGATATCTGTGGTCTGGTAAGCTTTCTACAACATTTGTATTA
AAACATTTCAGGTATTACTATGTATAGTGTTTATGGTATCATATAGCTTTTGGTAAGCACAGAT
TCTAGATCTGATCATAAAGAAATTGATAATGACTTCAATGACACTTTAAACCTGTAGTTAGAAA
GTAAAAATATAAAAATGACCTATCCGCTAACTTTTATCTTTAAAATAAATAAAATCTTGCTTAT
GTGACTATATGTTGAAACAAAAAATACCCCCTTGAAAATTACTTTGTGTACTTTATATTGATGA
TAATAAAGGAACCTTAAAATTT

hide sequence

Protein Sequences


Protein RefSeqs	XP_003129255	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000009688
	ENSSSCP00000009688.4
	ENSSSCP00025023108.1
	ENSSSCP00030042932.1
	ENSSSCP00035029617.1
	ENSSSCP00040024358.1
	ENSSSCP00045016475.1
	ENSSSCP00050017401.1
	ENSSSCP00055032767.1
	ENSSSCP00060039667.1
	ENSSSCP00065039138.1
	ENSSSCP00070039413.1

RefSeq Acc Id:

XP_003129255 ⟸ XM_003129207

- UniProtKB:

F1RRA6 (UniProtKB/TrEMBL), A0A4X1VCS0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQRESPKKKQEKKAEKRIFDAGSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE
AQYKGIVDCLVRIPREQGFFSYWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRW
FLANLAAGGAAGATSLCVVYPLDFARTRLGADIGKGPEERQFKGLGDCIVKIAKSDGIVGLYQG
FGVSVQGIIVYRASYFGAYDTVKGLLPKPKETPFLISFFIAQVVTTCSGILSYPFDTVRRRMMM
QSGETERQYKGTLDCFVKIYQHEGISAFFRGAFSNILRGTGGALVLVLYDKIKDFLNIDIGSSS
SGD

hide sequence

Ensembl Acc Id:

ENSSSCP00000009688 ⟸ ENSSSCT00000009944

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000009078	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025039933	UniProtKB/TrEMBL
	ENSSSCG00030066770	UniProtKB/TrEMBL
	ENSSSCG00035054706	UniProtKB/TrEMBL
	ENSSSCG00040043594	UniProtKB/TrEMBL
	ENSSSCG00045014029	UniProtKB/TrEMBL
	ENSSSCG00050031272	UniProtKB/TrEMBL
	ENSSSCG00055020981	UniProtKB/TrEMBL
	ENSSSCG00060067315	UniProtKB/TrEMBL
	ENSSSCG00065065208	UniProtKB/TrEMBL
	ENSSSCG00070023446	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000009944	ENTREZGENE
	ENSSSCT00000009944.5	UniProtKB/TrEMBL
	ENSSSCT00025054225.1	UniProtKB/TrEMBL
	ENSSSCT00030093273.1	UniProtKB/TrEMBL
	ENSSSCT00035072990.1	UniProtKB/TrEMBL
	ENSSSCT00040058371.1	UniProtKB/TrEMBL
	ENSSSCT00045023893.1	UniProtKB/TrEMBL
	ENSSSCT00050042050.1	UniProtKB/TrEMBL
	ENSSSCT00055041167.1	UniProtKB/TrEMBL
	ENSSSCT00060091817.1	UniProtKB/TrEMBL
	ENSSSCT00065089496.1	UniProtKB/TrEMBL
	ENSSSCT00070046723.1	UniProtKB/TrEMBL
Gene3D-CATH	1.50.40.10	UniProtKB/TrEMBL
InterPro	Aden_trnslctor	UniProtKB/TrEMBL
	Mit_carrier	UniProtKB/TrEMBL
	Mitochondrial_sb/sol_carrier	UniProtKB/TrEMBL
	Mt_carrier_dom_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100518564	UniProtKB/TrEMBL
NCBI Gene	SLC25A31	ENTREZGENE
PANTHER	ADP/ATP TRANSLOCASE 4	UniProtKB/TrEMBL
	PTHR45635	UniProtKB/TrEMBL
Pfam	Mito_carr	UniProtKB/TrEMBL
PRINTS	ADPTRNSLCASE	UniProtKB/TrEMBL
	MITOCARRIER	UniProtKB/TrEMBL
PROSITE	SOLCAR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103506	UniProtKB/TrEMBL
UniProt	A0A4X1VCS0	ENTREZGENE, UniProtKB/TrEMBL
	F1RRA6	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:93008	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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