Slc25a31 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Slc25a31 (solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31) Mus musculus
Analyze
Symbol: Slc25a31
Name: solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
RGD ID: 1619970
MGI Page MGI
Description: Predicted to enable ATP:ADP antiporter activity. Involved in male meiosis I; regulation of mitochondrial membrane permeability; and spermatogenesis. Located in mitochondrial inner membrane. Part of mitochondrial permeability transition pore complex. Is expressed in genitourinary system; lung; pituitary gland; and vertebral axis musculature. Orthologous to human SLC25A31 (solute carrier family 25 member 31).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1700034J06Rik; adenine nucleotide translocase 4; adenine nucleotide translocator 4; ADP,ATP carrier protein 4; ADP/ATP translocase 4; ANT 4; Ant4; Sfec; solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 31; solute carrier family 25 member 31; sperm flagellar energy carrier protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39340,663,301 - 40,680,525 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl340,663,285 - 40,680,527 (+)EnsemblGRCm39 Ensembl
GRCm38340,708,871 - 40,726,094 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl340,708,855 - 40,726,096 (+)EnsemblGRCm38mm10GRCm38
MGSCv37340,512,793 - 40,530,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36340,805,481 - 40,822,142 (+)NCBIMGSCv36mm8
Celera340,438,962 - 40,456,166 (+)NCBICelera
Cytogenetic Map3BNCBI
cM Map319.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
2. Mouse MP Annotation Import Pipeline RGD automated import pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12865426   PMID:14681479   PMID:16141072   PMID:16141073   PMID:17137571   PMID:17681941  
PMID:18614015   PMID:18667754   PMID:19556438   PMID:20439742   PMID:21267068   PMID:21677750   PMID:21858006   PMID:21873635   PMID:23665500   PMID:25031318   PMID:27739607   PMID:28378742  
PMID:29459677   PMID:30457570   PMID:30914420   PMID:31138677   PMID:31489369   PMID:34117224   PMID:35531097   PMID:37624892   PMID:38808891  


Genomics

Comparative Map Data
Slc25a31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39340,663,301 - 40,680,525 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl340,663,285 - 40,680,527 (+)EnsemblGRCm39 Ensembl
GRCm38340,708,871 - 40,726,094 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl340,708,855 - 40,726,096 (+)EnsemblGRCm38mm10GRCm38
MGSCv37340,512,793 - 40,530,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36340,805,481 - 40,822,142 (+)NCBIMGSCv36mm8
Celera340,438,962 - 40,456,166 (+)NCBICelera
Cytogenetic Map3BNCBI
cM Map319.5NCBI
SLC25A31
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384127,730,400 - 127,774,292 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4127,730,400 - 127,774,292 (+)EnsemblGRCh38hg38GRCh38
GRCh374128,651,555 - 128,695,447 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364128,871,024 - 128,914,897 (+)NCBINCBI36Build 36hg18NCBI36
Celera4126,030,533 - 126,074,415 (+)NCBICelera
Cytogenetic Map4q28.1NCBI
HuRef4124,379,238 - 124,423,119 (+)NCBIHuRef
CHM1_14128,628,022 - 128,671,905 (+)NCBICHM1_1
T2T-CHM13v2.04131,033,425 - 131,077,300 (+)NCBIT2T-CHM13v2.0
Slc25a31
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82125,623,331 - 125,639,155 (+)NCBIGRCr8
mRatBN7.22123,695,387 - 123,711,275 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2123,695,408 - 123,710,795 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02127,538,323 - 127,554,276 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2127,538,659 - 127,554,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02147,143,351 - 147,159,292 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42127,652,328 - 127,667,553 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2118,603,774 - 118,619,883 (+)NCBICelera
Cytogenetic Map2q26NCBI
Slc25a31
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542813,648,699 - 13,667,133 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542813,648,753 - 13,667,133 (-)NCBIChiLan1.0ChiLan1.0
SLC25A31
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23125,493,722 - 125,537,861 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14125,759,835 - 125,803,989 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04119,894,274 - 119,938,168 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14131,200,402 - 131,244,034 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4131,200,402 - 131,243,952 (+)Ensemblpanpan1.1panPan2
SLC25A31
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11913,164,134 - 13,190,346 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1913,164,245 - 13,276,496 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1913,352,774 - 13,378,984 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01913,254,200 - 13,280,433 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1913,254,307 - 13,280,283 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11913,227,346 - 13,253,552 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01913,512,863 - 13,539,135 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01913,974,826 - 14,001,040 (-)NCBIUU_Cfam_GSD_1.0
Slc25a31
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530161,628,301 - 61,652,793 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366422,921,852 - 3,025,083 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366422,921,629 - 2,945,577 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A31
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl897,095,517 - 97,120,250 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1897,095,503 - 97,120,940 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28103,958,654 - 103,983,983 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A31
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1774,857,296 - 74,892,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl774,857,818 - 74,892,156 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603753,991,729 - 54,027,399 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a31
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247778,676,083 - 8,700,281 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247778,676,933 - 8,700,198 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:83
Interacting mature miRNAs:84
Transcripts:ENSMUST00000091184
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
14746977Manh53_mmandible shape 53 (mouse)33592528069925280Mouse
15039332Nmrs6_mNAFLD-associated magnetic resonance shift 6 (mouse)33417074168170741Mouse
1301585Cd4ts1_mCD4 T cell subset 1 (mouse)Not determined33970410273704231Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
11041901Lmr11b_mleishmaniasis resistance 11b (mouse)33970410273704231Mouse
15039336Nmrs2_mNAFLD-associated magnetic resonance shift 2 (mouse)33457610368576103Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
10755516Amzn1_manatomical modifier of Zfp423 1 (mouse)33970410273704231Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3758617468716946Mouse
9587784Afw13_mabdominal fat weight QTL 13 (mouse)Not determined33375204567752228Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1301114Ssial2_msusceptibility to sialadenitis 2 (mouse)Not determined32017486254180103Mouse
1357689Mdmsc1_mmodifier of muscularity 1 (mouse)Not determined33332720145916479Mouse
18337272Bmd46_mbone mineral density 46, males (mouse)33540742169407421Mouse
11039513Ltpr3a_mLeishmania tropica response 3a (mouse)33970410273704231Mouse
1300961Bh4p_mbar holding four paws (mouse)Not determined33183785465837997Mouse
4142092Tgq13_mtriglyceride QTL 13 (mouse)Not determined1828816852288168Mouse
10043882Bwtq13_mbody weight QTL 13 (mouse)Not determined33375204567752228Mouse
10412073Ssen2_msuseptibility to Sendai virus 2 (mouse)Not determined33353546567535615Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
12910781Pwgrq12_mpost-weaning growth rate QTL 12 (mouse)33263576058017363Mouse
1300587Aod2_mautoimmune ovarian dysgenesis 2 (mouse)Not determined33717974268716946Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31163045345630591Mouse
12910778Pwgrq13_mpost-weaning growth rate QTL 13 (mouse)33263576058017363Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000091184   ⟹   ENSMUSP00000088723
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl340,663,285 - 40,680,527 (+)Ensembl
GRCm38.p6 Ensembl340,708,855 - 40,726,096 (+)Ensembl
RefSeq Acc Id: NM_178386   ⟹   NP_848473
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39340,663,301 - 40,680,525 (+)NCBI
GRCm38340,708,871 - 40,726,094 (+)ENTREZGENE
MGSCv37340,512,793 - 40,530,016 (+)RGD
Celera340,438,962 - 40,456,166 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_848473   ⟸   NM_178386
- UniProtKB: Q80W28 (UniProtKB/Swiss-Prot),   Q3V132 (UniProtKB/Swiss-Prot),   B2RTC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000088723   ⟸   ENSMUST00000091184

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3V132-F1-model_v2 AlphaFold Q3V132 1-320 view protein structure

Promoters
RGD ID:6834469
Promoter ID:MM_KWN:34181
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour,   ES_Cell
Transcripts:OTTMUST00000054219
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36340,512,544 - 40,513,044 (+)MPROMDB
RGD ID:6880544
Promoter ID:EPDNEW_M3722
Type:initiation region
Name:Slc25a31_1
Description:Mus musculus solute carrier family 25 (mitochondrial carrier;adenine nucleotide translocator), member 31 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38340,708,880 - 40,708,940EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1920583 AgrOrtholog
Ensembl Genes ENSMUSG00000069041 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000091184 ENTREZGENE
  ENSMUST00000091184.9 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Aden_trnslctor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mit_carrier UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:73333 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1920583 ENTREZGENE
NCBI Gene 73333 ENTREZGENE
PANTHER ADP/ATP TRANSLOCASE 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45635 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Mito_carr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc25a31 PhenoGen
PRINTS ADPTRNSLCASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MITOCARRIER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SOLCAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ADT4_MOUSE UniProtKB/Swiss-Prot
  B2RTC8 ENTREZGENE, UniProtKB/TrEMBL
  Q3V132 ENTREZGENE
  Q80W28 ENTREZGENE
UniProt Secondary Q80W28 UniProtKB/Swiss-Prot