NGDN (neuroguidin) - Rat Genome Database

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Gene: NGDN (neuroguidin) Sus scrofa
Analyze
Symbol: NGDN
Name: neuroguidin
RGD ID: 14102395
Description: INVOLVED IN negative regulation of protein localization to plasma membrane (ortholog); postsynaptic modulation of chemical synaptic transmission (ortholog); regulation of translation at postsynapse (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); Specific Granule Deficiency (ortholog); FOUND IN glutamatergic synapse (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: neuroguidin, EIF4E binding protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1775,621,334 - 75,629,447 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,107,079 - 81,115,187 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:30032202  


Genomics

Comparative Map Data
NGDN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1775,621,334 - 75,629,447 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,107,079 - 81,115,187 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NGDN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,469,703 - 23,478,826 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,469,679 - 23,509,862 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,938,912 - 23,948,035 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,008,738 - 23,017,242 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,008,755 - 23,017,853NCBI
Celera143,801,578 - 3,810,079 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,055,311 - 4,063,812 (+)NCBIHuRef
CHM1_11423,937,565 - 23,946,068 (+)NCBICHM1_1
T2T-CHM13v2.01417,670,297 - 17,679,414 (+)NCBIT2T-CHM13v2.0
Ngdn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,252,911 - 55,261,595 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,252,911 - 55,261,594 (+)EnsemblGRCm39 Ensembl
GRCm381455,015,454 - 55,024,138 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,015,454 - 55,024,137 (+)EnsemblGRCm38mm10GRCm38
MGSCv371455,634,291 - 55,642,975 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,969,596 - 53,978,209 (+)NCBIMGSCv36mm8
Celera1452,821,923 - 52,830,481 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.03NCBI
Ngdn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,459,898 - 32,467,260 (+)NCBIGRCr8
mRatBN7.21528,489,950 - 28,497,286 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,490,040 - 28,519,654 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,335,757 - 30,343,003 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,482,954 - 31,490,200 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,725,617 - 29,732,863 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,677,333 - 33,684,840 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,677,597 - 33,684,840 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,564,770 - 37,571,979 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,123,040 - 33,130,280 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,139,359 - 33,145,777 (+)NCBI
Celera1528,068,294 - 28,075,327 (+)NCBICelera
Cytogenetic Map15p13NCBI
Ngdn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,877,343 - 36,887,031 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,877,343 - 36,887,031 (-)NCBIChiLan1.0ChiLan1.0
NGDN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,900,885 - 24,909,229 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,117,377 - 24,125,720 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,288,325 - 4,296,671 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,382,340 - 22,390,718 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,382,334 - 22,390,718 (+)Ensemblpanpan1.1panPan2
NGDN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,704,430 - 3,713,517 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,705,005 - 3,713,517 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,626,408 - 3,635,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,814,513 - 3,823,622 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,815,156 - 3,823,622 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,506,015 - 3,515,129 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,567,476 - 3,576,588 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,829,536 - 3,838,646 (+)NCBIUU_Cfam_GSD_1.0
Ngdn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,447,004 - 35,456,656 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722932,238 - 942,046 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722932,336 - 941,895 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NGDN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,840,583 - 23,848,726 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,840,639 - 23,849,653 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605922,569,926 - 22,578,108 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ngdn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,092,139 - 9,102,192 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,092,270 - 9,102,189 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in NGDN
132 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


RefSeq Acc Id: NM_001244788   ⟹   NP_001231717
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1775,621,339 - 75,629,447 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021098198   ⟹   XP_020953857
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1775,621,334 - 75,629,323 (-)NCBI
Sequence:
RefSeq Acc Id: XP_020953857   ⟸   XM_021098198
- Peptide Label: isoform X1
- UniProtKB: A0A8D0ZRE9 (UniProtKB/TrEMBL),   A0A8D1CG67 (UniProtKB/TrEMBL),   A0A8D0LN79 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001231717   ⟸   NM_001244788
- UniProtKB: A0A4X1SIH2 (UniProtKB/TrEMBL),   A0A287ARE1 (UniProtKB/TrEMBL),   A0A8D1WPP4 (UniProtKB/TrEMBL),   A0A8D0TH53 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000002020 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005021667 UniProtKB/TrEMBL
  ENSSSCG00015021397 UniProtKB/TrEMBL
  ENSSSCG00025072633 UniProtKB/TrEMBL
  ENSSSCG00030065532 UniProtKB/TrEMBL
  ENSSSCG00035041751 UniProtKB/TrEMBL
  ENSSSCG00040021491 UniProtKB/TrEMBL
  ENSSSCG00045000737 UniProtKB/TrEMBL
  ENSSSCG00050054452 UniProtKB/TrEMBL
  ENSSSCG00055010951 UniProtKB/TrEMBL
  ENSSSCG00060069336 UniProtKB/TrEMBL
  ENSSSCG00065025245 UniProtKB/TrEMBL
  ENSSSCG00070001386 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000002259.4 UniProtKB/TrEMBL
  ENSSSCT00000059165 ENTREZGENE
  ENSSSCT00000059165.3 UniProtKB/TrEMBL
  ENSSSCT00005034554.1 UniProtKB/TrEMBL
  ENSSSCT00005034632.1 UniProtKB/TrEMBL
  ENSSSCT00005034657.1 UniProtKB/TrEMBL
  ENSSSCT00015028256.1 UniProtKB/TrEMBL
  ENSSSCT00015028396.1 UniProtKB/TrEMBL
  ENSSSCT00025099878.1 UniProtKB/TrEMBL
  ENSSSCT00025099995.1 UniProtKB/TrEMBL
  ENSSSCT00030091563.1 UniProtKB/TrEMBL
  ENSSSCT00030091585.1 UniProtKB/TrEMBL
  ENSSSCT00035055494.1 UniProtKB/TrEMBL
  ENSSSCT00035055511.1 UniProtKB/TrEMBL
  ENSSSCT00035055522.1 UniProtKB/TrEMBL
  ENSSSCT00040028866.1 UniProtKB/TrEMBL
  ENSSSCT00040028883.1 UniProtKB/TrEMBL
  ENSSSCT00045001058.1 UniProtKB/TrEMBL
  ENSSSCT00045001081.1 UniProtKB/TrEMBL
  ENSSSCT00050074246.1 UniProtKB/TrEMBL
  ENSSSCT00050074249.1 UniProtKB/TrEMBL
  ENSSSCT00055021518.1 UniProtKB/TrEMBL
  ENSSSCT00055021549.1 UniProtKB/TrEMBL
  ENSSSCT00060094711.1 UniProtKB/TrEMBL
  ENSSSCT00060094776.1 UniProtKB/TrEMBL
  ENSSSCT00065033785.1 UniProtKB/TrEMBL
  ENSSSCT00065033794.1 UniProtKB/TrEMBL
  ENSSSCT00070002601.1 UniProtKB/TrEMBL
  ENSSSCT00070002604.1 UniProtKB/TrEMBL
InterPro Sas10/Utp3/C1D UniProtKB/TrEMBL
KEGG Report ssc:100513213 UniProtKB/TrEMBL
NCBI Gene NGDN ENTREZGENE
PANTHER NEUROGUIDIN UniProtKB/TrEMBL
  PTHR13237 UniProtKB/TrEMBL
Pfam Sas10_Utp3 UniProtKB/TrEMBL
UniProt A0A287ARE1 ENTREZGENE
  A0A4X1SIH2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SJE1_PIG UniProtKB/TrEMBL
  A0A8D0J2X9_PIG UniProtKB/TrEMBL
  A0A8D0LN79 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0MYZ5_PIG UniProtKB/TrEMBL
  A0A8D0TH53 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0XUW0_PIG UniProtKB/TrEMBL
  A0A8D0ZRE9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CG67 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1WKQ9_PIG UniProtKB/TrEMBL
  A0A8D1WPP4 ENTREZGENE, UniProtKB/TrEMBL
  F1SS37_PIG UniProtKB/TrEMBL
UniProt Secondary A0A287ARE1 UniProtKB/TrEMBL