RNASE4 (ribonuclease A family member 4) - Rat Genome Database

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Gene: RNASE4 (ribonuclease A family member 4) Sus scrofa
Analyze
Symbol: RNASE4
Name: ribonuclease A family member 4
RGD ID: 14068090
Description: ENCODES a protein that exhibits endonuclease activity (inferred); nucleic acid binding (inferred); RNA nuclease activity (inferred); INVOLVED IN antibacterial humoral response (ortholog); cellular response to starvation (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 10 (ortholog); amyotrophic lateral sclerosis type 9 (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ribonuclease 4; ribonuclease PL3; RNase 4; RNase PL3; RNS4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,243,691 - 78,244,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,244,284 - 78,244,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:2611266   PMID:8019417   PMID:14681463   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNASE4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,243,691 - 78,244,930 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,244,284 - 78,244,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNASE4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,684,560 - 20,701,216 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,684,560 - 20,701,216 (+)EnsemblGRCh38hg38GRCh38
GRCh371421,152,719 - 21,169,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,222,212 - 20,238,598 (+)NCBINCBI36Build 36hg18NCBI36
Build 341420,226,771 - 20,238,597NCBI
Celera141,013,244 - 1,029,632 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,273,295 - 1,289,678 (+)NCBIHuRef
CHM1_11421,154,392 - 21,170,774 (+)NCBICHM1_1
T2T-CHM13v2.01414,881,670 - 14,898,327 (+)NCBIT2T-CHM13v2.0
Rnase4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,328,534 - 51,343,608 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,328,534 - 51,343,608 (+)EnsemblGRCm39 Ensembl
GRCm381451,091,077 - 51,106,151 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,091,077 - 51,106,151 (+)EnsemblGRCm38mm10GRCm38
MGSCv371451,710,752 - 51,725,826 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361450,013,147 - 50,028,091 (+)NCBIMGSCv36mm8
MGSCv361442,955,672 - 42,970,033 (+)NCBIMGSCv36mm8
Celera1447,385,172 - 47,400,997 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.37NCBI
Rnase4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,786,287 - 26,803,634 (+)NCBIGRCr8
mRatBN7.21524,312,765 - 24,330,112 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,312,464 - 24,330,117 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,083,931 - 27,101,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,043,091 - 28,060,440 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,292,490 - 26,309,841 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,018,040 - 28,035,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,850,396 - 31,866,409 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,073,756 - 27,090,441 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,089,455 - 27,106,139 (+)NCBI
Celera1524,631,848 - 24,647,995 (+)NCBICelera
Cytogenetic Map15p14NCBI
RNASE4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,182,660 - 22,200,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,397,673 - 21,416,652 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,548,729 - 1,564,819 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,605,890 - 19,621,987 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,620,758 - 19,621,201 (+)Ensemblpanpan1.1panPan2
RNASE4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,981,661 - 17,998,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,981,647 - 18,004,631 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,467,471 - 18,484,458 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,242,716 - 18,259,707 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,242,716 - 18,260,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,924,113 - 17,941,085 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,980,204 - 17,997,189 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,107,982 - 18,124,962 (+)NCBIUU_Cfam_GSD_1.0
Rnase4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,124,933 - 32,133,608 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493688034,289 - 43,209 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493688041,940 - 42,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNASE4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,216,021 - 21,233,306 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,216,477 - 21,232,699 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,197,478 - 25,214,890 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in RNASE4
3 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSSCT00000044269   ⟹   ENSSSCP00000068285
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,691 - 78,244,930 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000076822   ⟹   ENSSSCP00000068632
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,714 - 78,244,930 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078526   ⟹   ENSSSCP00000068520
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,697 - 78,244,930 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000078860   ⟹   ENSSSCP00000071309
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl778,243,697 - 78,244,930 (-)Ensembl
RefSeq Acc Id: NM_213936   ⟹   NP_999101
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1778,244,284 - 78,244,931 (-)NCBI
Sequence:
RefSeq Acc Id: NP_999101   ⟸   NM_213936
- Peptide Label: precursor
- UniProtKB: P15468 (UniProtKB/Swiss-Prot),   A0A8D1GKI2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000068632   ⟸   ENSSSCT00000076822
Ensembl Acc Id: ENSSSCP00000068285   ⟸   ENSSSCT00000044269
Ensembl Acc Id: ENSSSCP00000071309   ⟸   ENSSSCT00000078860
Ensembl Acc Id: ENSSSCP00000068520   ⟸   ENSSSCT00000078526
Protein Domains
Ribonuclease A-domain


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031538 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005022658 UniProtKB/Swiss-Prot
  ENSSSCG00015081231 UniProtKB/Swiss-Prot
  ENSSSCG00025004731 UniProtKB/Swiss-Prot
  ENSSSCG00030041623 UniProtKB/Swiss-Prot
  ENSSSCG00035000933 UniProtKB/Swiss-Prot
  ENSSSCG00040017428 UniProtKB/Swiss-Prot
  ENSSSCG00045004300 UniProtKB/TrEMBL
  ENSSSCG00050003361 UniProtKB/Swiss-Prot
  ENSSSCG00055015921 UniProtKB/Swiss-Prot
  ENSSSCG00060027285 UniProtKB/Swiss-Prot
  ENSSSCG00065059715 UniProtKB/Swiss-Prot
Ensembl Transcript ENSSSCT00000044269.3 UniProtKB/TrEMBL
  ENSSSCT00000076822 ENTREZGENE
  ENSSSCT00000076822.2 UniProtKB/TrEMBL
  ENSSSCT00000078526.2 UniProtKB/TrEMBL
  ENSSSCT00000078860.2 UniProtKB/TrEMBL
  ENSSSCT00005035802 UniProtKB/Swiss-Prot
  ENSSSCT00005035824 UniProtKB/Swiss-Prot
  ENSSSCT00005035830 UniProtKB/Swiss-Prot
  ENSSSCT00005035911 UniProtKB/Swiss-Prot
  ENSSSCT00015110783.1 UniProtKB/Swiss-Prot
  ENSSSCT00015110784.1 UniProtKB/Swiss-Prot
  ENSSSCT00015110785.1 UniProtKB/Swiss-Prot
  ENSSSCT00015110787.1 UniProtKB/Swiss-Prot
  ENSSSCT00025006398.1 UniProtKB/Swiss-Prot
  ENSSSCT00025006399.1 UniProtKB/Swiss-Prot
  ENSSSCT00025006400.1 UniProtKB/Swiss-Prot
  ENSSSCT00025006404.1 UniProtKB/Swiss-Prot
  ENSSSCT00030057885.1 UniProtKB/Swiss-Prot
  ENSSSCT00030057889.1 UniProtKB/Swiss-Prot
  ENSSSCT00030057915.1 UniProtKB/Swiss-Prot
  ENSSSCT00030057932.1 UniProtKB/Swiss-Prot
  ENSSSCT00035001107.1 UniProtKB/Swiss-Prot
  ENSSSCT00035001111.1 UniProtKB/Swiss-Prot
  ENSSSCT00035001112.1 UniProtKB/Swiss-Prot
  ENSSSCT00035001122.1 UniProtKB/Swiss-Prot
  ENSSSCT00040023502.1 UniProtKB/Swiss-Prot
  ENSSSCT00040023524.1 UniProtKB/Swiss-Prot
  ENSSSCT00040023535.1 UniProtKB/Swiss-Prot
  ENSSSCT00040023599.1 UniProtKB/Swiss-Prot
  ENSSSCT00045007168.1 UniProtKB/TrEMBL
  ENSSSCT00045007172.1 UniProtKB/TrEMBL
  ENSSSCT00045007173.1 UniProtKB/TrEMBL
  ENSSSCT00045007178.1 UniProtKB/TrEMBL
  ENSSSCT00050004490.1 UniProtKB/Swiss-Prot
  ENSSSCT00050004495.1 UniProtKB/Swiss-Prot
  ENSSSCT00050004519.1 UniProtKB/Swiss-Prot
  ENSSSCT00050004539.1 UniProtKB/Swiss-Prot
  ENSSSCT00055031343.1 UniProtKB/Swiss-Prot
  ENSSSCT00055031368.1 UniProtKB/Swiss-Prot
  ENSSSCT00055031376.1 UniProtKB/Swiss-Prot
  ENSSSCT00055031463.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036938.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036949.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036953.1 UniProtKB/Swiss-Prot
  ENSSSCT00060036973.1 UniProtKB/Swiss-Prot
  ENSSSCT00065081779.1 UniProtKB/Swiss-Prot
  ENSSSCT00065081787.1 UniProtKB/Swiss-Prot
  ENSSSCT00065081792.1 UniProtKB/Swiss-Prot
  ENSSSCT00065081809.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.130.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RNaseA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseA_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396976 UniProtKB/Swiss-Prot
NCBI Gene RNASE4 ENTREZGENE
PANTHER PTHR11437 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBONUCLEASE 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RnaseA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS RIBONUCLEASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RNASE_PANCREATIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RNAse_Pc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54076 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5G2R2I5_PIG UniProtKB/TrEMBL
  A0A5G2R360_PIG UniProtKB/TrEMBL
  A0A8D1GKI2 ENTREZGENE, UniProtKB/TrEMBL
  P15468 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary A0A5G2QWJ4 UniProtKB/TrEMBL