RAB2B (RAB2B, member RAS oncogene family) - Rat Genome Database

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Gene: RAB2B (RAB2B, member RAS oncogene family) Sus scrofa
Analyze
Symbol: RAB2B
Name: RAB2B, member RAS oncogene family (Ensembl:RAB2B, member RAS onco family)
RGD ID: 14049869
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); INVOLVED IN defense response to virus (inferred); Golgi organization (inferred); innate immune response (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); cone-rod dystrophy 13 (ortholog); purine nucleoside phosphorylase deficiency (ortholog); FOUND IN presynapse (ortholog); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-2B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl777,689,551 - 77,716,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1777,698,907 - 77,717,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,040,992 - 83,059,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
GTP binding  (IBA,IEA)
GTPase activity  (IBA,IEA)
protein binding  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RAB2B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl777,689,551 - 77,716,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1777,698,907 - 77,717,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,040,992 - 83,059,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB2B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381421,459,020 - 21,476,959 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1421,459,020 - 21,476,960 (-)EnsemblGRCh38hg38GRCh38
GRCh371421,927,179 - 21,945,118 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,997,023 - 21,014,961 (-)NCBINCBI36Build 36hg18NCBI36
Build 341420,997,027 - 21,014,961NCBI
Celera141,792,578 - 1,810,513 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef142,046,741 - 2,064,378 (-)NCBIHuRef
CHM1_11421,928,654 - 21,946,603 (-)NCBICHM1_1
T2T-CHM13v2.01415,656,403 - 15,674,328 (-)NCBIT2T-CHM13v2.0
Rab2b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,499,216 - 52,516,852 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1452,499,216 - 52,517,002 (-)EnsemblGRCm39 Ensembl
GRCm381452,261,759 - 52,279,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1452,261,759 - 52,279,545 (-)EnsemblGRCm38mm10GRCm38
MGSCv371452,881,434 - 52,899,070 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361451,183,722 - 51,201,280 (-)NCBIMGSCv36mm8
Celera1449,244,192 - 49,261,935 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1426.87NCBI
Rab2b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,441,860 - 27,462,479 (-)NCBIGRCr8
mRatBN7.21524,968,364 - 24,988,990 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,968,803 - 24,989,113 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,742,428 - 27,761,686 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,696,681 - 28,715,783 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,949,627 - 26,968,722 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,675,504 - 28,696,192 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,677,055 - 28,696,122 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,485,704 - 32,506,397 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,708,937 - 27,729,229 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,724,998 - 27,744,664 (-)NCBI
Celera1525,273,808 - 25,293,145 (-)NCBICelera
Cytogenetic Map15p14NCBI
Rab2b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555502,180,326 - 2,195,523 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555502,180,326 - 2,195,523 (-)NCBIChiLan1.0ChiLan1.0
RAB2B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,914,464 - 22,932,434 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11422,130,951 - 22,148,921 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,276,798 - 2,294,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11420,353,701 - 20,371,629 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1420,353,701 - 20,371,629 (-)Ensemblpanpan1.1panPan2
RAB2B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,494,417 - 18,512,144 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,495,891 - 18,512,030 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,978,908 - 18,996,652 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,753,341 - 18,771,113 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,753,342 - 18,771,002 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11518,435,482 - 18,453,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,491,516 - 18,509,245 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,620,377 - 18,638,114 (-)NCBIUU_Cfam_GSD_1.0
Rab2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,701,507 - 32,718,815 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936880610,878 - 628,753 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936880610,903 - 628,176 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB2B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,927,529 - 21,946,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,927,107 - 21,946,012 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605924,484,242 - 24,503,031 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab2b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,478,151 - 7,493,649 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,477,729 - 7,493,669 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RAB2B
326 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000027841   ⟹   ENSSSCP00000024266
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl777,689,551 - 77,716,761 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000048308   ⟹   ENSSSCP00000038177
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl777,699,219 - 77,716,772 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000086323   ⟹   ENSSSCP00000060945
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl777,699,219 - 77,716,759 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000086920   ⟹   ENSSSCP00000060638
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl777,689,551 - 77,713,867 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000095496   ⟹   ENSSSCP00000078717
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl777,689,551 - 77,714,100 (+)Ensembl
RefSeq Acc Id: XM_013978245   ⟹   XP_013833699
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1777,698,907 - 77,717,211 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013978246   ⟹   XP_013833700
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1777,698,932 - 77,717,211 (+)NCBI
Sequence:
RefSeq Acc Id: XP_013833699   ⟸   XM_013978245
- Peptide Label: isoform X1
- UniProtKB: F1S8J6 (UniProtKB/TrEMBL),   A0A4X1UYK3 (UniProtKB/TrEMBL),   A0A8W4FHK4 (UniProtKB/TrEMBL),   A0A8D0RT92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013833700   ⟸   XM_013978246
- Peptide Label: isoform X2
- UniProtKB: A0A287A2L2 (UniProtKB/TrEMBL),   A0A4X1UZR8 (UniProtKB/TrEMBL),   A0A8D1DC00 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000024266   ⟸   ENSSSCT00000027841
Ensembl Acc Id: ENSSSCP00000060945   ⟸   ENSSSCT00000086323
Ensembl Acc Id: ENSSSCP00000038177   ⟸   ENSSSCT00000048308
Ensembl Acc Id: ENSSSCP00000060638   ⟸   ENSSSCT00000086920
Ensembl Acc Id: ENSSSCP00000078717   ⟸   ENSSSCT00000095496


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000029544 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005018573 UniProtKB/TrEMBL
  ENSSSCG00015010647 UniProtKB/TrEMBL
  ENSSSCG00025036276 UniProtKB/TrEMBL
  ENSSSCG00030024398 UniProtKB/TrEMBL
  ENSSSCG00035012423 UniProtKB/TrEMBL
  ENSSSCG00040009659 UniProtKB/TrEMBL
  ENSSSCG00045002852 UniProtKB/TrEMBL
  ENSSSCG00050004270 UniProtKB/TrEMBL
  ENSSSCG00055028311 UniProtKB/TrEMBL
  ENSSSCG00060018881 UniProtKB/TrEMBL
  ENSSSCG00065048825 UniProtKB/TrEMBL
  ENSSSCG00070020629 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027841 ENTREZGENE
  ENSSSCT00000027841.3 UniProtKB/TrEMBL
  ENSSSCT00000048308 ENTREZGENE
  ENSSSCT00000048308.1 UniProtKB/TrEMBL
  ENSSSCT00000086323.2 UniProtKB/TrEMBL
  ENSSSCT00000086920.1 UniProtKB/TrEMBL
  ENSSSCT00000095496.1 UniProtKB/TrEMBL
  ENSSSCT00005029571.1 UniProtKB/TrEMBL
  ENSSSCT00005029583.1 UniProtKB/TrEMBL
  ENSSSCT00005029597.1 UniProtKB/TrEMBL
  ENSSSCT00005029623.1 UniProtKB/TrEMBL
  ENSSSCT00015013968.1 UniProtKB/TrEMBL
  ENSSSCT00015014035.1 UniProtKB/TrEMBL
  ENSSSCT00025049454.1 UniProtKB/TrEMBL
  ENSSSCT00025049520.1 UniProtKB/TrEMBL
  ENSSSCT00030033974.1 UniProtKB/TrEMBL
  ENSSSCT00030033986.1 UniProtKB/TrEMBL
  ENSSSCT00035015656.1 UniProtKB/TrEMBL
  ENSSSCT00035015673.1 UniProtKB/TrEMBL
  ENSSSCT00040012492.1 UniProtKB/TrEMBL
  ENSSSCT00040012535.1 UniProtKB/TrEMBL
  ENSSSCT00045004502.1 UniProtKB/TrEMBL
  ENSSSCT00045004534.1 UniProtKB/TrEMBL
  ENSSSCT00050005887.1 UniProtKB/TrEMBL
  ENSSSCT00050005891.1 UniProtKB/TrEMBL
  ENSSSCT00055056140.1 UniProtKB/TrEMBL
  ENSSSCT00055056256.1 UniProtKB/TrEMBL
  ENSSSCT00060025395.1 UniProtKB/TrEMBL
  ENSSSCT00060025407.1 UniProtKB/TrEMBL
  ENSSSCT00065066812.1 UniProtKB/TrEMBL
  ENSSSCT00065066826.1 UniProtKB/TrEMBL
  ENSSSCT00070040996.1 UniProtKB/TrEMBL
  ENSSSCT00070041003.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rab_GTPases_membrane_traffic UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report ssc:100516623 UniProtKB/TrEMBL
NCBI Gene RAB2B ENTREZGENE
PANTHER DRAB11-RELATED UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-2B UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287A2L2 ENTREZGENE
  A0A4X1UYK3 ENTREZGENE
  A0A4X1UZR8 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2Q9L1_PIG UniProtKB/TrEMBL
  A0A8D0RT92 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1CLT2_PIG UniProtKB/TrEMBL
  A0A8D1DC00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FHK4 ENTREZGENE, UniProtKB/TrEMBL
  F1S8J6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287A2L2 UniProtKB/TrEMBL
  A0A4X1UYK3 UniProtKB/TrEMBL
  A0A5G2QFY1 UniProtKB/TrEMBL
VGNC ID VGNC:98253 ENTREZGENE