PLCD3 (phospholipase C delta 3) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: PLCD3 (phospholipase C delta 3) Sus scrofa
Analyze
Symbol: PLCD3
Name: phospholipase C delta 3
RGD ID: 14043135
Description: ENCODES a protein that exhibits hydrolase activity (inferred); phosphatidylinositol phospholipase C activity (inferred); INVOLVED IN angiogenesis (ortholog); labyrinthine layer blood vessel development (ortholog); regulation of cell population proliferation (ortholog); PARTICIPATES IN inositol metabolic pathway; ASSOCIATED WITH hereditary breast ovarian cancer syndrome (ortholog); FOUND IN nucleoplasm (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,281,502 - 18,302,483 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,281,507 - 18,305,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,530,472 - 18,551,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLCD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,281,502 - 18,302,483 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,281,507 - 18,305,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,530,472 - 18,551,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381745,108,959 - 45,132,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1745,108,959 - 45,133,354 (-)EnsemblGRCh38hg38GRCh38
GRCh371743,186,327 - 43,209,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,544,534 - 40,565,417 (-)NCBINCBI36Build 36hg18NCBI36
Build 341740,544,543 - 40,565,391NCBI
Celera1739,898,162 - 39,919,051 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1738,952,185 - 38,972,987 (-)NCBIHuRef
CHM1_11743,424,536 - 43,445,418 (-)NCBICHM1_1
T2T-CHM13v2.01745,962,835 - 45,986,399 (-)NCBIT2T-CHM13v2.0
Plcd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,960,062 - 102,992,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,961,130 - 102,992,484 (-)EnsemblGRCm39 Ensembl
GRCm3811103,070,296 - 103,101,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11103,070,304 - 103,101,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711102,931,610 - 102,962,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,886,400 - 102,917,692 (-)NCBIMGSCv36mm8
Celera11114,788,919 - 114,811,158 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.71NCBI
Plcd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81088,526,802 - 88,548,116 (-)NCBIGRCr8
mRatBN7.21088,026,707 - 88,048,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1088,026,740 - 88,048,296 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1093,062,952 - 93,084,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01092,529,623 - 92,550,923 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01087,922,965 - 87,944,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01091,164,778 - 91,186,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1091,164,812 - 91,186,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01090,937,117 - 90,958,001 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41092,234,651 - 92,275,433 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11092,249,509 - 92,291,067 (-)NCBI
Celera1086,728,695 - 86,749,683 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Plcd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,822,761 - 17,827,846 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,822,345 - 17,827,848 (-)NCBIChiLan1.0ChiLan1.0
PLCD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21919,704,918 - 19,725,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11721,673,497 - 21,694,350 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,194,761 - 12,215,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,370,389 - 12,391,667 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,371,299 - 12,390,691 (+)Ensemblpanpan1.1panPan2
PLCD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1918,399,946 - 18,419,630 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl918,400,039 - 18,419,560 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,784,845 - 17,804,314 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,073,110 - 19,092,576 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,073,110 - 19,092,582 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1917,951,365 - 17,970,806 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,130,204 - 18,149,674 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0918,286,182 - 18,305,568 (+)NCBIUU_Cfam_GSD_1.0
Plcd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560217,748,001 - 17,768,280 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365411,426,580 - 1,446,286 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365411,426,590 - 1,446,286 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,277,813 - 61,300,891 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1661,277,917 - 61,300,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,024,853 - 32,046,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624795270,722 - 282,390 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624795270,760 - 282,789 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLCD3
757 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000018874   ⟹   ENSSSCP00000018370
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1218,281,502 - 18,302,483 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000052926   ⟹   ENSSSCP00000052852
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1218,291,753 - 18,302,484 (+)Ensembl
Ensembl Acc Id: ENSSSCT00000077866   ⟹   ENSSSCP00000061487
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1218,291,753 - 18,302,483 (+)Ensembl
RefSeq Acc Id: XM_003131325   ⟹   XP_003131373
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11218,281,507 - 18,305,516 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013980896   ⟹   XP_013836350
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11218,286,135 - 18,305,516 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021066845   ⟹   XP_020922504
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11218,281,756 - 18,302,480 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003131373   ⟸   XM_003131325
- Peptide Label: isoform X1
- UniProtKB: F1RR07 (UniProtKB/TrEMBL),   A0A8D1WPZ9 (UniProtKB/TrEMBL),   A0A4X1TDM6 (UniProtKB/TrEMBL),   A0A8D1D3A7 (UniProtKB/TrEMBL),   A0A8D1MVH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020922504   ⟸   XM_021066845
- Peptide Label: isoform X2
- UniProtKB: A0A4X1TDM6 (UniProtKB/TrEMBL),   A0A8D1D3A7 (UniProtKB/TrEMBL),   A0A8D1MVH7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013836350   ⟸   XM_013980896
- Peptide Label: isoform X3
- UniProtKB: A0A4X1TDM6 (UniProtKB/TrEMBL),   A0A8D1D3A7 (UniProtKB/TrEMBL),   A0A8D1MVH7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000052852   ⟸   ENSSSCT00000052926
Ensembl Acc Id: ENSSSCP00000018370   ⟸   ENSSSCT00000018874
Ensembl Acc Id: ENSSSCP00000061487   ⟸   ENSSSCT00000077866
Protein Domains
C2   PH   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017338 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025039146 UniProtKB/TrEMBL
  ENSSSCG00030056525 UniProtKB/TrEMBL
  ENSSSCG00035070451 UniProtKB/TrEMBL
  ENSSSCG00040034086 UniProtKB/TrEMBL
  ENSSSCG00045013350 UniProtKB/TrEMBL
  ENSSSCG00050048167 UniProtKB/TrEMBL
  ENSSSCG00055005555 UniProtKB/TrEMBL
  ENSSSCG00060070881 UniProtKB/TrEMBL
  ENSSSCG00065028936 UniProtKB/TrEMBL
  ENSSSCG00070008980 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000018874 ENTREZGENE
  ENSSSCT00000018874.5 UniProtKB/TrEMBL
  ENSSSCT00000077866 ENTREZGENE
  ENSSSCT00000077866.2 UniProtKB/TrEMBL
  ENSSSCT00025053332.1 UniProtKB/TrEMBL
  ENSSSCT00025053423.1 UniProtKB/TrEMBL
  ENSSSCT00025053514.1 UniProtKB/TrEMBL
  ENSSSCT00030079024.1 UniProtKB/TrEMBL
  ENSSSCT00030079149.1 UniProtKB/TrEMBL
  ENSSSCT00030079213.1 UniProtKB/TrEMBL
  ENSSSCT00035095283.1 UniProtKB/TrEMBL
  ENSSSCT00035095341.1 UniProtKB/TrEMBL
  ENSSSCT00035095393.1 UniProtKB/TrEMBL
  ENSSSCT00040045967.1 UniProtKB/TrEMBL
  ENSSSCT00040046030.1 UniProtKB/TrEMBL
  ENSSSCT00040046062.1 UniProtKB/TrEMBL
  ENSSSCT00045022817.1 UniProtKB/TrEMBL
  ENSSSCT00045022878.1 UniProtKB/TrEMBL
  ENSSSCT00045022913.1 UniProtKB/TrEMBL
  ENSSSCT00050065642.1 UniProtKB/TrEMBL
  ENSSSCT00055010964.1 UniProtKB/TrEMBL
  ENSSSCT00055011034.1 UniProtKB/TrEMBL
  ENSSSCT00055011092.1 UniProtKB/TrEMBL
  ENSSSCT00060096930.1 UniProtKB/TrEMBL
  ENSSSCT00060096973.1 UniProtKB/TrEMBL
  ENSSSCT00060096991.1 UniProtKB/TrEMBL
  ENSSSCT00065039078.1 UniProtKB/TrEMBL
  ENSSSCT00065039105.1 UniProtKB/TrEMBL
  ENSSSCT00065039121.1 UniProtKB/TrEMBL
  ENSSSCT00070017445.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-delta3_EF-hand UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
KEGG Report ssc:100521111 UniProtKB/TrEMBL
NCBI Gene PLCD3 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF33 UniProtKB/TrEMBL
Pfam EF-hand_10 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt A0A4X1TDM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QAQ4_PIG UniProtKB/TrEMBL
  A0A8D0RVW7_PIG UniProtKB/TrEMBL
  A0A8D1AV31_PIG UniProtKB/TrEMBL
  A0A8D1CD94_PIG UniProtKB/TrEMBL
  A0A8D1D2Z1_PIG UniProtKB/TrEMBL
  A0A8D1D3A7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1EA56_PIG UniProtKB/TrEMBL
  A0A8D1MVH7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1PW82_PIG UniProtKB/TrEMBL
  A0A8D1WMG6_PIG UniProtKB/TrEMBL
  A0A8D1WPZ9 ENTREZGENE, UniProtKB/TrEMBL
  F1RR07 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91518 ENTREZGENE