STAB2 (stabilin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: STAB2 (stabilin 2) Sus scrofa
Analyze
Symbol: STAB2
Name: stabilin 2
RGD ID: 14019215
Description: ENCODES a protein that exhibits cargo receptor activity (ortholog); scavenger receptor activity (ortholog); INVOLVED IN defense response to bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); endocytosis (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatocellular carcinoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN cytosol (ortholog); external side of plasma membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: stabilin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1580,692,459 - 80,863,221 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,332,946 - 84,425,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
STAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1580,692,459 - 80,863,221 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,332,946 - 84,425,221 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812103,587,273 - 103,766,719 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12103,587,273 - 103,766,719 (+)EnsemblGRCh38hg38GRCh38
GRCh3712103,981,051 - 104,160,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612102,505,199 - 102,684,632 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412102,483,535 - 102,662,967NCBI
Celera12103,644,967 - 103,824,194 (+)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12101,040,941 - 101,220,117 (+)NCBIHuRef
CHM1_112103,947,453 - 104,126,824 (+)NCBICHM1_1
T2T-CHM13v2.012103,548,545 - 103,728,010 (+)NCBIT2T-CHM13v2.0
Stab2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391086,677,058 - 86,843,902 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1086,677,062 - 86,843,889 (-)EnsemblGRCm39 Ensembl
GRCm381086,841,194 - 87,008,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,841,198 - 87,008,025 (-)EnsemblGRCm38mm10GRCm38
MGSCv371086,303,955 - 86,470,687 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361086,271,007 - 86,437,741 (-)NCBIMGSCv36mm8
Celera1088,822,759 - 88,979,326 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1043.14NCBI
Stab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8723,136,938 - 23,342,633 (-)NCBIGRCr8
mRatBN7.2721,249,426 - 21,433,051 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl721,249,391 - 21,434,042 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx723,223,948 - 23,405,067 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0725,386,660 - 25,567,761 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0725,163,729 - 25,344,850 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0727,369,853 - 27,552,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl727,369,853 - 27,552,078 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,488,874 - 27,666,514 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,470,117 - 23,497,983 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1723,490,342 - 23,518,256 (-)NCBI
Celera718,430,372 - 18,608,299 (-)NCBICelera
Cytogenetic Map7q13NCBI
Stab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540538,393,650 - 38,533,815 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540538,393,636 - 38,533,701 (+)NCBIChiLan1.0ChiLan1.0
STAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210111,733,831 - 111,829,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112111,648,668 - 111,825,921 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012101,165,854 - 101,343,144 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112104,561,264 - 104,738,599 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12104,561,264 - 104,738,599 (+)Ensemblpanpan1.1panPan2
STAB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11542,187,074 - 42,328,874 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1542,187,790 - 42,328,883 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1542,558,264 - 42,698,952 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01542,846,797 - 42,986,317 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1542,846,735 - 42,986,317 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11542,113,980 - 42,253,105 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01542,212,117 - 42,351,533 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01542,481,549 - 42,622,125 (+)NCBIUU_Cfam_GSD_1.0
Stab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494517,667,645 - 17,820,561 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649210,678,115 - 10,833,963 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649210,678,074 - 10,817,870 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11198,780,148 - 98,953,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1198,779,921 - 98,954,913 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037146,038,165 - 146,206,183 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stab2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,866,792 - 5,016,335 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247504,866,438 - 5,016,958 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STAB2
8557 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system
High
Medium 2 2
Low 2 1
Below cutoff 6 1 3 1 14 2 1

Sequence


Reference Sequences
RefSeq Acc Id: XM_021092647   ⟹   XP_020948306
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1580,692,459 - 80,863,221 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_020948306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSSCP00000000911
  ENSSSCP00000000911.4
Reference Protein Sequences
RefSeq Acc Id: XP_020948306   ⟸   XM_021092647
- UniProtKB: F1SRK1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
EGF-like   FAS1   Link


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000854 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000931 ENTREZGENE
  ENSSSCT00000000931.4 UniProtKB/TrEMBL
Gene3D-CATH 2.30.180.10 UniProtKB/TrEMBL
  3.10.100.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro C-type_lectin-like/link_sf UniProtKB/TrEMBL
  CTDL_fold UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF_dom UniProtKB/TrEMBL
  FAS1_dom_sf UniProtKB/TrEMBL
  FAS1_domain UniProtKB/TrEMBL
  Link_dom UniProtKB/TrEMBL
NCBI Gene STAB2 ENTREZGENE
PANTHER STABILIN UniProtKB/TrEMBL
  STABILIN-2 UniProtKB/TrEMBL
Pfam EGF_3 UniProtKB/TrEMBL
  Fasciclin UniProtKB/TrEMBL
  Xlink UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  FAS1 UniProtKB/TrEMBL
  LINK_1 UniProtKB/TrEMBL
  LINK_2 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FAS1 UniProtKB/TrEMBL
  LINK UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF56436 UniProtKB/TrEMBL
  SSF82153 UniProtKB/TrEMBL
UniProt F1SRK1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:112552 ENTREZGENE