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Gene: THOC6 (THO complex subunit 6) Sus scrofa

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Symbol:

THOC6

Name:

THO complex subunit 6

RGD ID:

13976401

Description:

INVOLVED IN central nervous system development (inferred); mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Beaulieu-Boycott-Innes Syndrome (ortholog); developmental and epileptic encephalopathy 1 (ortholog); epilepsy (ortholog); FOUND IN chromosome, telomeric region (inferred); nuclear body (inferred); nuclear speck (inferred); INTERACTS WITH deoxynivalenol

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

THO complex 6; THO complex 6 homolog; THO complex subunit 6 homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	THOC6 (THO complex subunit 6)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Thoc6 (THO complex 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Thoc6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Thoc6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	THOC6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	THOC6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Thoc6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	THOC6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Thoc6 (THO complex subunit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	39,161,434 - 39,164,707 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	39,161,442 - 39,164,631 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	40,535,339 - 40,538,529 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Beaulieu-Boycott-Innes Syndrome (ISO)

developmental and epileptic encephalopathy 1 (ISO)

epilepsy (ISO)

genetic disease (ISO)

idiopathic generalized epilepsy (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

central nervous system development (IEA)

mRNA export from nucleus (IBA,IEA)

Cellular Component

chromosome, telomeric region (IEA)

nuclear body (IEA)

nuclear speck (IEA)

nucleoplasm (IEA)

nucleus (IEA)

THO complex (IBA,IEA)

THO complex part of transcription export complex (IEA)

transcription export complex (IBA,IEA)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

NXF1-NXT1 export pathway (ISO)

References

Additional References at PubMed

PMID:12226715	PMID:14681463	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

THOC6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	39,161,434 - 39,164,707 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	39,161,442 - 39,164,631 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	40,535,339 - 40,538,529 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

THOC6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	3,024,035 - 3,027,750 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	3,024,027 - 3,027,755 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	3,074,036 - 3,077,751 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	3,014,094 - 3,017,752 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	3,279,588 - 3,283,311 (+)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	3,045,606 - 3,049,329 (+)	NCBI		HuRef
CHM1_1	16	3,073,906 - 3,077,630 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	3,050,607 - 3,054,322 (+)	NCBI		T2T-CHM13v2.0

Thoc6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	23,887,592 - 23,892,891 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	23,887,588 - 23,892,856 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	23,668,618 - 23,673,917 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	23,668,614 - 23,673,882 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	23,805,586 - 23,810,737 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	23,396,241 - 23,401,392 (-)	NCBI		MGSCv36	mm8
Celera	17	24,174,757 - 24,179,976 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	11.97	NCBI

Thoc6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	13,204,643 - 13,210,004 (-)	NCBI		GRCr8
mRatBN7.2	10	12,700,051 - 12,705,411 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	12,700,051 - 12,706,925 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	17,443,443 - 17,448,809 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	16,932,232 - 16,937,602 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	12,432,693 - 12,438,058 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	12,989,135 - 12,994,495 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	12,989,135 - 12,994,495 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	12,812,180 - 12,817,540 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	12,933,304 - 12,938,664 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	12,933,477 - 12,934,565 (-)	NCBI
Celera	10	12,395,353 - 12,400,712 (-)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Thoc6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	14,314,100 - 14,317,724 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	14,314,100 - 14,317,726 (-)	NCBI	ChiLan1.0	ChiLan1.0

THOC6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	3,568,797 - 3,572,552 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	7,347,397 - 7,350,925 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	1,965,875 - 1,969,595 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	3,138,217 - 3,141,878 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	3,138,229 - 3,141,876 (+)	Ensembl	panpan1.1		panPan2

THOC6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	38,161,506 - 38,164,287 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	38,161,474 - 38,164,402 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	39,402,042 - 39,405,030 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	38,472,101 - 38,475,089 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	38,472,105 - 38,475,079 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	38,157,896 - 38,160,884 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	38,130,403 - 38,133,392 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	38,606,159 - 38,609,147 (-)	NCBI		UU_Cfam_GSD_1.0

Thoc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	105,561,935 - 105,565,339 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	1,143,345 - 1,147,345 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	1,144,122 - 1,147,345 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

THOC6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	2,767,338 - 2,771,040 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	2,767,634 - 2,771,812 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	28,061,270 - 28,065,055 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Thoc6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624824	768,082 - 774,688 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla_female_1.0 Ensembl	NW_004624824	764,217 - 766,210 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624824	764,185 - 772,426 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in THOC6
17 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001243684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005662202	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK351693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF191751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP312929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01097805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000026356 ⟹ ENSSSCP00000020539

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	39,161,434 - 39,164,625 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000037747 ⟹ ENSSSCP00000052094

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	39,161,445 - 39,164,707 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000042790 ⟹ ENSSSCP00000043339

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	39,161,445 - 39,164,622 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000050374 ⟹ ENSSSCP00000031297

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	3	39,161,444 - 39,164,649 (-)	Ensembl

RefSeq Acc Id:

NM_001243684 ⟹ NP_001230613

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	39,161,442 - 39,164,631 (-)	NCBI

Sequence:

show sequence

GAGTCTGCGCAGGCGCGGAAGGCTGACGGCACGCGGCTGGAAGGCGGGTCTGCTCTGCGGGGTG
GGGGCGGGGGCCCGCCGTAGCGGGGTTGCGGTGGGTACCACTTAGTCTTGGGATCTTCTTGGCG
GTCACCTGCGCTGCTGGGACTCGGGTTACGCAGAGGCCGTCTTCACGCCGGGCTGGCCAGCGGT
GTTGGGGAGGTAGGGCGCCGCGAAGGGGAGCTGCTCCGGAGGCACTTCCGGACTCGTGAGGCTA
CGTGGAGCGCGGAGCTCTCTGGGACTTTTAGTTCTCGAGATGGACCGAGCGGTGCCGCCGGCGG
TGCCTCTGGGTCAGATGGAAGTATTTCAGGCCCTGCAGCGGCTGCACATGACCATCTTCTCCCA
GAGTGTCTCACCTTGTGGGAAGTTCCTGGCGGCTGGCAACAATTATGGGCAGATAGCCATCTTT
AGCTTGTCTGCTGCTCTGAGCTCCGAGGCCAAAGAGGAAAGTAAGAAGCCCATTGTGACTTTCC
AAGCCCATGATGGGCCTGTCTACAGCATGGTGTCCACTGATCGACATCTGCTCAGTGCCGGGGA
TGGGGAGGTGAAGGCCTGGCTTTGGGCGGAGATCCTTAAGAAGGGCTGTAAGGAGCTGTGGCGT
CGTCAGCCCCCATACAGGACCAGCCTAGAAGTACCTGAGATCAATGCTTTACTTCTCGTCCCCA
AGGAGAATTCCCTCATCCTGGCGGGTGGAGACTGTCAGCTGCACACGATGGACCTTGAGACGGG
GGCCTTCACCCGGGCCCTCCGCGGCCACACAGACTACATCCACTGCCTGGCGCTGAGGGAGAGG
AGCCCCGAGGTGCTCTCTGGTGGCGAGGATGGGGCCGTACGGCTCTGGGACCTCCGCACGGCCA
GGGAGGTCCAGACGATCGAAGTCTACAAGCATGAGGAGTGCTCGAGGCCCCACAATGGGCGCTG
GATCGGATGTTTGGCAACTGACTCAGACTGGATGGTCTGTGGAGGTGGCCCGGCACTCACCCTC
TGGCACCTTCGATCTTCCACACCCACCACCATCTTCCCCATGCGGGCACCGCAGAAGCACGTTA
CCTTCTACCAGGACCTGATTCTGTCAGCTGGCCAGGGTCGCTGCGTCAACCAGTGGCAGCTGAG
TGGGGAGCTCAAGGCTCAGGTGCCTGGCTCCTCCCCTGGGCTGCTGAGCCTCAGCCTCAACCAG
CAACCAGCAGCCCCTGAGTGCAAGGTTCTGACAGCTGCAGGCAACAGCTGCAGGGTGGACGTTT
TCACCAATCTGGGCTACCGAGCTTTCTCCCTGTCCTTCTGAGCTGCAGCAGCGCCTCCACATCC
ATCTCCGGAGTCTGGAGTGTTTCTTCTTTTTTTATACAAATAAAGTTTTAGGCTTTTTTTTTCA
TGCAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_005662202 ⟹ XP_005662259

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	3	39,161,442 - 39,164,272 (-)	NCBI

Sequence:

show sequence

CTTCTGGGGTTTGTAGTCCACGCCCGGCTTCGAAGCGGCTGGCAAGCAGTCGTGCCCTGATCTC
TGTTTCGCGTGGGCTCTTGGTGGGACTCGGATTCTGACCCGTGGGCGGGAGAATAACCCAGAAA
TACCTCAGGGGCCTTACATGAAAGTCAAAAGATGGAAGTATTTCAGGCCCTGCAGCGGCTGCAC
ATGACCATCTTCTCCCAGAGTGTCTCACCTTGTGGGAAGTTCCTGGCGGCTGGCAACAATTATG
GGCAGATAGCCATCTTTAGCTTGTCTGCTGCTCTGAGCTCCGAGGCCAAAGAGGAAAGTAAGAA
GCCCATTGTGACTTTCCAAGCCCATGATGGGCCTGTCTACAGCATGGTGTCCACTGATCGACAT
CTGCTCAGTGCCGGGGATGGGGAGGTGAAGGCCTGGCTTTGGGCGGAGATCCTTAAGAAGGGCT
GTAAGGAGCTGTGGCGTCGTCAGCCCCCATACAGGACCAGCCTAGAAGTACCTGAGATCAATGC
TTTACTTCTCGTCCCCAAGGAGAATTCCCTCATCCTGGCGGGTGGAGACTGTCAGCTGCACACG
ATGGACCTTGAGACGGGGGCCTTCACCCGGGCCCTCCGCGGCCACACAGACTACATCCACTGCC
TGGCGCTGAGGGAGAGGAGCCCCGAGGTGCTCTCTGGTGGCGAGGATGGGGCCGTACGGCTCTG
GGACCTCCGCACGGCCAGGGAGGTCCAGACGATCGAAGTCTACAAGCATGAGGAGTGCTCGAGG
CCCCACAATGGGCGCTGGATCGGATGTTTGGCAACTGACTCAGACTGGATGGTCTGTGGAGGTG
GCCCGGCACTCACCCTCTGGCACCTTCGATCTTCCACACCCACCACCATCTTCCCCATGCGGGC
ACCGCAGAAGCACGTTACCTTCTACCAGGACCTGATTCTGTCAGCTGGCCAGGGTCGCTGCGTC
AACCAGTGGCAGCTGAGTGGGGAGCTCAAGGCTCAGGTGCCTGGCTCCTCCCCTGGGCTGCTGA
GCCTCAGCCTCAACCAGCAACCAGCAGCCCCTGAGTGCAAGGTTCTGACAGCTGCAGGCAACAG
CTGCAGGGTGGACGTTTTCACCAATCTGGGCTACCGAGCTTTCTCCCTGTCCTTCTGAGCTGCA
GCAGCGCCTCCACATCCATCTCCGGAGTCTGGAGTGTTTCTTCTTTTTTTTATACAAATAAAGT
TTTAGGCTTTTTTTTTCATGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001230613	(Get FASTA)	NCBI Sequence Viewer
	XP_005662259	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000020539.2
	ENSSSCP00000031297
	ENSSSCP00000031297.2
	ENSSSCP00000043339.2
	ENSSSCP00000052094
	ENSSSCP00000052094.1
	ENSSSCP00015040004.1
	ENSSSCP00015040085.1
	ENSSSCP00015040390.1
	ENSSSCP00025006382.1
	ENSSSCP00025006416.1
	ENSSSCP00025006528.1
	ENSSSCP00030012776.1
	ENSSSCP00030012783.1
	ENSSSCP00030012790.1
	ENSSSCP00035027103.1
	ENSSSCP00035027111.1
	ENSSSCP00035027132.1
	ENSSSCP00040016000.1
	ENSSSCP00040016079.1
	ENSSSCP00040016109.1
	ENSSSCP00045008496.1
	ENSSSCP00045008536.1
	ENSSSCP00045008575.1
	ENSSSCP00050010723.1
	ENSSSCP00050010754.1
	ENSSSCP00055031733.1
	ENSSSCP00055031840.1
	ENSSSCP00055031917.1
	ENSSSCP00060043239.1
	ENSSSCP00060043630.1
	ENSSSCP00060043766.1
	ENSSSCP00065016329.1
	ENSSSCP00065016335.1
	ENSSSCP00065016362.1
	ENSSSCP00070045139.1
	ENSSSCP00070045140.1
	ENSSSCP00070045141.1

RefSeq Acc Id:

NP_001230613 ⟸ NM_001243684

- UniProtKB:

A0A286ZII9 (UniProtKB/TrEMBL), A0A4X1VSU3 (UniProtKB/TrEMBL), A0A8D1C278 (UniProtKB/TrEMBL), I3L928 (UniProtKB/TrEMBL), A0A8D0HP96 (UniProtKB/TrEMBL), A0A8D1E5C2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDRAVPPAVPLGQMEVFQALQRLHMTIFSQSVSPCGKFLAAGNNYGQIAIFSLSAALSSEAKEE
SKKPIVTFQAHDGPVYSMVSTDRHLLSAGDGEVKAWLWAEILKKGCKELWRRQPPYRTSLEVPE
INALLLVPKENSLILAGGDCQLHTMDLETGAFTRALRGHTDYIHCLALRERSPEVLSGGEDGAV
RLWDLRTAREVQTIEVYKHEECSRPHNGRWIGCLATDSDWMVCGGGPALTLWHLRSSTPTTIFP
MRAPQKHVTFYQDLILSAGQGRCVNQWQLSGELKAQVPGSSPGLLSLSLNQQPAAPECKVLTAA
GNSCRVDVFTNLGYRAFSLSF

hide sequence

RefSeq Acc Id:	XP_005662259 ⟸ XM_005662202
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D0PY80 (UniProtKB/TrEMBL), A0A8D0VZT8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEVFQALQRLHMTIFSQSVSPCGKFLAAGNNYGQIAIFSLSAALSSEAKEESKKPIVTFQAHDG PVYSMVSTDRHLLSAGDGEVKAWLWAEILKKGCKELWRRQPPYRTSLEVPEINALLLVPKENSL ILAGGDCQLHTMDLETGAFTRALRGHTDYIHCLALRERSPEVLSGGEDGAVRLWDLRTAREVQT IEVYKHEECSRPHNGRWIGCLATDSDWMVCGGGPALTLWHLRSSTPTTIFPMRAPQKHVTFYQD LILSAGQGRCVNQWQLSGELKAQVPGSSPGLLSLSLNQQPAAPECKVLTAAGNSCRVDVFTNLG YRAFSLSF hide sequence

Ensembl Acc Id:

ENSSSCP00000031297 ⟸ ENSSSCT00000050374

Ensembl Acc Id:

ENSSSCP00000020539 ⟸ ENSSSCT00000026356

Ensembl Acc Id:

ENSSSCP00000043339 ⟸ ENSSSCT00000042790

Ensembl Acc Id:

ENSSSCP00000052094 ⟸ ENSSSCT00000037747

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000023315	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015072383	UniProtKB/TrEMBL
	ENSSSCG00025012138	UniProtKB/TrEMBL
	ENSSSCG00030020670	UniProtKB/TrEMBL
	ENSSSCG00035050173	UniProtKB/TrEMBL
	ENSSSCG00040028299	UniProtKB/TrEMBL
	ENSSSCG00045007336	UniProtKB/TrEMBL
	ENSSSCG00050019125	UniProtKB/TrEMBL
	ENSSSCG00055020096	UniProtKB/TrEMBL
	ENSSSCG00060072832	UniProtKB/TrEMBL
	ENSSSCG00065028668	UniProtKB/TrEMBL
	ENSSSCG00070026583	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000026356.2	UniProtKB/TrEMBL
	ENSSSCT00000037747	ENTREZGENE
	ENSSSCT00000037747.3	UniProtKB/TrEMBL
	ENSSSCT00000042790.2	UniProtKB/TrEMBL
	ENSSSCT00000050374	ENTREZGENE
	ENSSSCT00000050374.3	UniProtKB/TrEMBL
	ENSSSCT00015097309.1	UniProtKB/TrEMBL
	ENSSSCT00015097536.1	UniProtKB/TrEMBL
	ENSSSCT00015098199.1	UniProtKB/TrEMBL
	ENSSSCT00025016088.1	UniProtKB/TrEMBL
	ENSSSCT00025016160.1	UniProtKB/TrEMBL
	ENSSSCT00025016411.1	UniProtKB/TrEMBL
	ENSSSCT00030028643.1	UniProtKB/TrEMBL
	ENSSSCT00030028657.1	UniProtKB/TrEMBL
	ENSSSCT00030028665.1	UniProtKB/TrEMBL
	ENSSSCT00035066859.1	UniProtKB/TrEMBL
	ENSSSCT00035066872.1	UniProtKB/TrEMBL
	ENSSSCT00035066907.1	UniProtKB/TrEMBL
	ENSSSCT00040038327.1	UniProtKB/TrEMBL
	ENSSSCT00040038477.1	UniProtKB/TrEMBL
	ENSSSCT00040038543.1	UniProtKB/TrEMBL
	ENSSSCT00045012413.1	UniProtKB/TrEMBL
	ENSSSCT00045012458.1	UniProtKB/TrEMBL
	ENSSSCT00045012512.1	UniProtKB/TrEMBL
	ENSSSCT00050025872.1	UniProtKB/TrEMBL
	ENSSSCT00050025956.1	UniProtKB/TrEMBL
	ENSSSCT00055039904.1	UniProtKB/TrEMBL
	ENSSSCT00055040027.1	UniProtKB/TrEMBL
	ENSSSCT00055040115.1	UniProtKB/TrEMBL
	ENSSSCT00060099670.1	UniProtKB/TrEMBL
	ENSSSCT00060100458.1	UniProtKB/TrEMBL
	ENSSSCT00060100732.1	UniProtKB/TrEMBL
	ENSSSCT00065038664.1	UniProtKB/TrEMBL
	ENSSSCT00065038674.1	UniProtKB/TrEMBL
	ENSSSCT00065038721.1	UniProtKB/TrEMBL
	ENSSSCT00070053278.1	UniProtKB/TrEMBL
	ENSSSCT00070053279.1	UniProtKB/TrEMBL
	ENSSSCT00070053280.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	THOC6	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	ssc:100626533	UniProtKB/TrEMBL
NCBI Gene	THOC6	ENTREZGENE
PANTHER	PTHR44411	UniProtKB/TrEMBL
	THO COMPLEX SUBUNIT 6 HOMOLOG	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A286ZII9	ENTREZGENE, UniProtKB/TrEMBL
	A0A287B720_PIG	UniProtKB/TrEMBL
	A0A4X1VNL1_PIG	UniProtKB/TrEMBL
	A0A4X1VSU3	ENTREZGENE
	A0A4X1VU18_PIG	UniProtKB/TrEMBL
	A0A8D0HP96	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0PY80	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0VZT8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1AD39_PIG	UniProtKB/TrEMBL
	A0A8D1C278	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1E5C2	ENTREZGENE, UniProtKB/TrEMBL
	I3L928	ENTREZGENE
UniProt Secondary	A0A287AHG1	UniProtKB/TrEMBL
	A0A4X1VSU3	UniProtKB/TrEMBL
	I3L928	UniProtKB/TrEMBL
VGNC ID	VGNC:93959	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-29	THOC6	THO complex subunit 6	THOC6	THO complex 6	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations