THOC6 (THO complex subunit 6) - Rat Genome Database

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Gene: THOC6 (THO complex subunit 6) Canis lupus familiaris
Analyze
Symbol: THOC6
Name: THO complex subunit 6
RGD ID: 12244409
Description: INVOLVED IN central nervous system development (ortholog); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH Beaulieu-Boycott-Innes Syndrome (ortholog); cryptorchidism (ortholog); Developmental Disabilities (ortholog); FOUND IN chromosome, telomeric region (ortholog); nucleoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: THO complex 6; THO complex 6 homolog; THO complex subunit 6 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,161,506 - 38,164,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,161,474 - 38,164,402 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha639,402,042 - 39,405,030 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0638,472,101 - 38,475,089 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,472,105 - 38,475,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,157,896 - 38,160,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,130,403 - 38,133,392 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,606,159 - 38,609,147 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
THOC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,161,506 - 38,164,287 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,161,474 - 38,164,402 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha639,402,042 - 39,405,030 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0638,472,101 - 38,475,089 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,472,105 - 38,475,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,157,896 - 38,160,884 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,130,403 - 38,133,392 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,606,159 - 38,609,147 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
THOC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,024,035 - 3,027,750 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,022,541 - 3,027,755 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh37163,074,036 - 3,077,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,014,094 - 3,017,752 (+)NCBIBuild 36Build 36hg18NCBI36
Celera163,279,588 - 3,283,311 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef163,045,606 - 3,049,329 (+)NCBIHuRef
CHM1_1163,073,906 - 3,077,630 (+)NCBICHM1_1
T2T-CHM13v2.0163,050,607 - 3,054,322 (+)NCBIT2T-CHM13v2.0
Thoc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391723,887,592 - 23,892,891 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1723,887,586 - 23,894,346 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381723,668,618 - 23,673,917 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,668,614 - 23,673,882 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv371723,805,586 - 23,810,737 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361723,396,241 - 23,401,392 (-)NCBIMGSCv36mm8
Celera1724,174,757 - 24,179,976 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1711.97NCBI
Thoc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,204,643 - 13,210,004 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1013,204,644 - 13,210,004 (-)EnsemblGRCr8
mRatBN7.21012,700,051 - 12,705,411 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,700,051 - 12,706,925 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1017,443,443 - 17,448,809 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,932,232 - 16,937,602 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,432,693 - 12,438,058 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1016,128,320 - 16,133,683 (-)NCBI
Lyon_Normotensive1016,788,028 - 16,793,393 (-)NCBI
Lyon_Hypertensive1018,481,654 - 18,487,017 (-)NCBI
F344_StmMcwi1018,472,569 - 18,477,934 (-)NCBI
Rnor_6.01012,989,135 - 12,994,495 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,989,135 - 12,994,495 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01012,812,180 - 12,817,540 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41012,933,304 - 12,938,664 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1012,395,353 - 12,400,712 (-)NCBICelera
RGSC_v3.11012,933,477 - 12,934,565 (-)NCBI
Cytogenetic Map10q12NCBI
Thoc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,314,100 - 14,317,724 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495544214,314,100 - 14,317,726 (-)NCBIChiLan1.0ChiLan1.0
THOC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,568,797 - 3,572,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,347,397 - 7,350,925 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,965,875 - 1,969,595 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,138,217 - 3,141,878 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,138,229 - 3,141,876 (+)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Thoc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap110138,020,320 - 138,023,593 (+)NCBImIctTri1.hap1
HiC_Itri_2NW_024409344105,561,935 - 105,565,339 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,143,345 - 1,147,345 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,144,122 - 1,147,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
THOC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,161,434 - 39,164,707 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1339,161,442 - 39,164,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,535,339 - 40,538,529 (+)NCBISscrofa10.2Sscrofa10.2susScr3
THOC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap153,028,909 - 3,032,388 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366606828,061,270 - 28,065,055 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.152,767,338 - 2,771,040 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,767,634 - 2,771,812 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Thoc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624824764,185 - 772,426 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624824768,082 - 774,688 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla_female_1.0 EnsemblNW_004624824764,217 - 766,210 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2346,220,702 - 46,229,648 (+)Ensembl
Thoc6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v19975,557 - 980,593 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in THOC6
16 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000030703   ⟹   ENSCAFP00000028537
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,161,563 - 38,164,402 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000066594   ⟹   ENSCAFP00000049474
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,161,474 - 38,164,402 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000071293   ⟹   ENSCAFP00000052009
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,161,582 - 38,164,402 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000075417   ⟹   ENSCAFP00000044004
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,161,563 - 38,164,402 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000078513   ⟹   ENSCAFP00000052846
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl638,161,563 - 38,164,402 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845005540   ⟹   ENSCAFP00845004396
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl638,472,105 - 38,475,079 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845005568   ⟹   ENSCAFP00845004419
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl638,472,105 - 38,475,079 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845005577   ⟹   ENSCAFP00845004423
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl638,472,185 - 38,475,079 (-)Ensembl
RefSeq Acc Id: XM_038479368   ⟹   XP_038335296
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1638,157,896 - 38,160,884 (-)NCBI
RefSeq Acc Id: XM_038540630   ⟹   XP_038396558
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0638,606,159 - 38,609,147 (-)NCBI
RefSeq Acc Id: XM_038604741   ⟹   XP_038460669
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0638,130,403 - 38,133,392 (-)NCBI
RefSeq Acc Id: XM_038669425   ⟹   XP_038525353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0638,472,101 - 38,475,089 (-)NCBI
RefSeq Acc Id: XM_536996   ⟹   XP_536996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1638,161,506 - 38,164,287 (-)NCBI
Dog10K_Boxer_Tasha639,402,042 - 39,405,030 (-)NCBI
Sequence:
RefSeq Acc Id: XP_536996   ⟸   XM_536996
- UniProtKB: A0A8I3MPA7 (UniProtKB/TrEMBL),   A0A8I3ML35 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000052846   ⟸   ENSCAFT00000078513
Ensembl Acc Id: ENSCAFP00000028537   ⟸   ENSCAFT00000030703
Ensembl Acc Id: ENSCAFP00000049474   ⟸   ENSCAFT00000066594
Ensembl Acc Id: ENSCAFP00000044004   ⟸   ENSCAFT00000075417
Ensembl Acc Id: ENSCAFP00000052009   ⟸   ENSCAFT00000071293
RefSeq Acc Id: XP_038335296   ⟸   XM_038479368
RefSeq Acc Id: XP_038460669   ⟸   XM_038604741
RefSeq Acc Id: XP_038525353   ⟸   XM_038669425
- UniProtKB: A0A8I3MPA7 (UniProtKB/TrEMBL),   A0A8I3ML35 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038396558   ⟸   XM_038540630
- UniProtKB: A0A8I3ML35 (UniProtKB/TrEMBL),   A0A8I3MPA7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845004419   ⟸   ENSCAFT00845005568
Ensembl Acc Id: ENSCAFP00845004396   ⟸   ENSCAFT00845005540
Ensembl Acc Id: ENSCAFP00845004423   ⟸   ENSCAFT00845005577
Protein Domains
Nucleolar protein 10-like N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019317 Ensembl
  ENSCAFG00845003143 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845005540.1 UniProtKB/TrEMBL
  ENSCAFT00845005568 ENTREZGENE
  ENSCAFT00845005568.1 UniProtKB/TrEMBL
  ENSCAFT00845005577.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro Beta-prop_NOL10_N UniProtKB/TrEMBL
  THOC6 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:479871 UniProtKB/TrEMBL
NCBI Gene THOC6 ENTREZGENE
PANTHER PTHR44411 UniProtKB/TrEMBL
  THO COMPLEX SUBUNIT 6 HOMOLOG UniProtKB/TrEMBL
Pfam Beta-prop_NOL10_N UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A8I3MJE4_CANLF UniProtKB/TrEMBL
  A0A8I3ML35 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MPA7 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47352 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-29 THOC6  THO complex subunit 6  THOC6  THO complex 6  Symbol and/or name change 19259463 PROVISIONAL