AP3S2 (adaptor-related protein complex 3, sigma 2 subunit) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: AP3S2 (adaptor-related protein complex 3, sigma 2 subunit) Sus scrofa
Analyze
Symbol: AP3S2
Name: adaptor-related protein complex 3, sigma 2 subunit
RGD ID: 13922791
Description: INVOLVED IN anterograde axonal transport (inferred); anterograde synaptic vesicle transport (inferred); Golgi to vacuole transport (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); D-2-hydroxyglutaric aciduria 2 (ortholog); FOUND IN synaptic vesicle (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AP-3 complex subunit sigma-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,391,913 - 55,469,858 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1755,395,159 - 55,462,352 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,284,224 - 60,346,605 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:15469932   PMID:15679890   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AP3S2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl755,391,913 - 55,469,858 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1755,395,159 - 55,462,352 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2760,284,224 - 60,346,605 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AP3S2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381589,830,599 - 89,893,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1589,830,599 - 89,894,638 (-)EnsemblGRCh38hg38GRCh38
GRCh371590,373,831 - 90,437,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361588,177,792 - 88,238,206 (-)NCBINCBI36Build 36hg18NCBI36
Build 341588,177,792 - 88,238,206NCBI
Celera1566,776,618 - 66,840,633 (-)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1566,486,975 - 66,549,513 (-)NCBIHuRef
CHM1_11590,214,856 - 90,279,356 (-)NCBICHM1_1
T2T-CHM13v2.01587,586,470 - 87,650,001 (-)NCBIT2T-CHM13v2.0
Ap3s2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39779,525,073 - 79,570,388 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl779,525,073 - 79,570,397 (-)EnsemblGRCm39 Ensembl
GRCm38779,875,325 - 79,920,640 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl779,875,325 - 79,920,649 (-)EnsemblGRCm38mm10GRCm38
MGSCv37787,020,211 - 87,065,526 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36779,748,838 - 79,794,114 (-)NCBIMGSCv36mm8
Celera777,274,187 - 77,319,524 (-)NCBICelera
Cytogenetic Map7D2NCBI
cM Map745.23NCBI
Ap3s2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81143,228,131 - 143,268,573 (-)NCBIGRCr8
mRatBN7.21133,818,825 - 133,859,269 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,818,825 - 133,859,322 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1141,728,397 - 141,768,822 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01148,897,804 - 148,938,229 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01141,815,521 - 141,855,945 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01141,612,961 - 141,655,417 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1141,612,963 - 141,655,894 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01142,574,433 - 142,615,225 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41135,653,104 - 135,689,454 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1125,881,750 - 125,917,424 (-)NCBICelera
Cytogenetic Map1q31NCBI
AP3S2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21679,384,158 - 79,441,788 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11583,086,501 - 83,142,705 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01568,524,982 - 68,583,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11587,727,539 - 87,786,121 (-)NCBIpanpan1.1PanPan1.1panPan2
AP3S2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1352,807,462 - 52,865,290 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl352,807,462 - 52,865,245 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha355,441,326 - 55,498,112 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0353,224,171 - 53,281,084 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl353,222,853 - 53,281,066 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1352,745,895 - 52,802,647 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0352,955,926 - 53,012,923 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0353,296,286 - 53,353,136 (-)NCBIUU_Cfam_GSD_1.0
Ap3s2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640130,673,609 - 130,724,763 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648315,613,474 - 15,660,838 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648315,613,474 - 15,660,862 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0

Variants

.
Variants in AP3S2
927 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000025884   ⟹   ENSSSCP00000024872
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl755,391,913 - 55,462,346 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000056139   ⟹   ENSSSCP00000040490
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl755,395,899 - 55,462,823 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000059305   ⟹   ENSSSCP00000049304
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl755,391,913 - 55,462,346 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000101525   ⟹   ENSSSCP00000079053
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl755,395,906 - 55,469,858 (-)Ensembl
RefSeq Acc Id: NM_001244548   ⟹   NP_001231477
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1755,395,159 - 55,462,352 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001231477   ⟸   NM_001244548
- UniProtKB: A0A287AZL8 (UniProtKB/TrEMBL),   A0A4X1TYY4 (UniProtKB/TrEMBL),   I3LLA5 (UniProtKB/TrEMBL),   A0A4X1U1C5 (UniProtKB/TrEMBL),   A0A8D0LNH5 (UniProtKB/TrEMBL),   A0A8D1TBT7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000049304   ⟸   ENSSSCT00000059305
Ensembl Acc Id: ENSSSCP00000040490   ⟸   ENSSSCT00000056139
Ensembl Acc Id: ENSSSCP00000024872   ⟸   ENSSSCT00000025884
Ensembl Acc Id: ENSSSCP00000079053   ⟸   ENSSSCT00000101525
Protein Domains
AP complex mu/sigma subunit


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000030174 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005024045 UniProtKB/TrEMBL
  ENSSSCG00015027150 UniProtKB/TrEMBL
  ENSSSCG00030016554 UniProtKB/TrEMBL
  ENSSSCG00035058808 UniProtKB/TrEMBL
  ENSSSCG00050028779 UniProtKB/TrEMBL
  ENSSSCG00055014446 UniProtKB/TrEMBL
  ENSSSCG00060067734 UniProtKB/TrEMBL
  ENSSSCG00065041526 UniProtKB/TrEMBL
  ENSSSCG00070013390 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000025884 ENTREZGENE
  ENSSSCT00000025884.4 UniProtKB/TrEMBL
  ENSSSCT00000056139.3 UniProtKB/TrEMBL
  ENSSSCT00000059305.2 UniProtKB/TrEMBL
  ENSSSCT00000101525.1 UniProtKB/TrEMBL
  ENSSSCT00005038101.1 UniProtKB/TrEMBL
  ENSSSCT00005038124.1 UniProtKB/TrEMBL
  ENSSSCT00005038185.1 UniProtKB/TrEMBL
  ENSSSCT00015036147.1 UniProtKB/TrEMBL
  ENSSSCT00030022921.1 UniProtKB/TrEMBL
  ENSSSCT00035078729.1 UniProtKB/TrEMBL
  ENSSSCT00050038689.1 UniProtKB/TrEMBL
  ENSSSCT00055028657.1 UniProtKB/TrEMBL
  ENSSSCT00060092470.1 UniProtKB/TrEMBL
  ENSSSCT00065056819.1 UniProtKB/TrEMBL
  ENSSSCT00070026136.1 UniProtKB/TrEMBL
  ENSSSCT00070026143.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.60 UniProtKB/TrEMBL
InterPro AP_complex_ssu UniProtKB/TrEMBL
  AP_mu_sigma_su UniProtKB/TrEMBL
  APS3 UniProtKB/TrEMBL
  Clathrin_sm-chain_CS UniProtKB/TrEMBL
  Longin-like_dom_sf UniProtKB/TrEMBL
KEGG Report ssc:100153862 UniProtKB/TrEMBL
NCBI Gene AP3S2 ENTREZGENE
PANTHER AP-3 COMPLEX SUBUNIT SIGMA-2 UniProtKB/TrEMBL
  PTHR11753 UniProtKB/TrEMBL
Pfam Clat_adaptor_s UniProtKB/TrEMBL
PROSITE CLAT_ADAPTOR_S UniProtKB/TrEMBL
Superfamily-SCOP SSF64356 UniProtKB/TrEMBL
UniProt A0A287AZL8 ENTREZGENE
  A0A4X1TYY4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U1C5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LNH5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1AM03_PIG UniProtKB/TrEMBL
  A0A8D1TBT7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FI98_PIG UniProtKB/TrEMBL
  I3LLA5 ENTREZGENE
UniProt Secondary A0A287A9D8 UniProtKB/TrEMBL
  A0A287AZL8 UniProtKB/TrEMBL
  I3LLA5 UniProtKB/TrEMBL