SEPHS1 (selenophosphate synthetase 1) - Rat Genome Database

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Gene: SEPHS1 (selenophosphate synthetase 1) Sus scrofa
Analyze
Symbol: SEPHS1
Name: selenophosphate synthetase 1
RGD ID: 13853329
Description: ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN selenocysteine biosynthetic process (inferred); ASSOCIATED WITH genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN cytoplasm (inferred); nuclear membrane (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: selenide, water dikinase 1; SEPHS1_tv1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,362,463 - 48,386,431 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,359,379 - 48,385,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15679890   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SEPHS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1048,362,463 - 48,386,431 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11048,359,379 - 48,385,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SEPHS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,317,428 - 13,348,293 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,317,428 - 13,348,298 (-)EnsemblGRCh38hg38GRCh38
GRCh371013,359,428 - 13,390,293 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,400,086 - 13,430,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 341013,400,088 - 13,430,286NCBI
Celera1013,287,201 - 13,317,394 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,272,252 - 13,328,716 (-)NCBIHuRef
CHM1_11013,360,412 - 13,391,270 (-)NCBICHM1_1
T2T-CHM13v2.01013,330,509 - 13,361,341 (-)NCBIT2T-CHM13v2.0
Sephs1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,886,375 - 4,915,368 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,886,375 - 4,915,368 (+)EnsemblGRCm39 Ensembl
GRCm3824,881,564 - 4,910,557 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,881,564 - 4,910,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv3724,802,610 - 4,831,603 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3624,798,836 - 4,827,829 (+)NCBIMGSCv36mm8
Celera24,836,684 - 4,865,647 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map23.02NCBI
Sephs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,263,725 - 78,296,132 (-)NCBIGRCr8
mRatBN7.21773,354,435 - 73,382,803 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,356,530 - 73,382,593 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1776,859,200 - 76,887,672 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,683,806 - 80,712,417 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01774,735,128 - 74,763,491 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,312,562 - 77,340,934 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1777,312,562 - 77,340,934 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01778,978,379 - 79,006,698 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,443,153 - 84,473,434 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,456,080 - 84,484,517 (-)NCBI
Celera1772,795,028 - 72,823,505 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Sephs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542920,847,861 - 20,871,074 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542920,849,526 - 20,871,074 (+)NCBIChiLan1.0ChiLan1.0
SEPHS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2825,837,666 - 25,868,751 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11025,843,004 - 25,874,079 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,316,013 - 13,347,087 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,649,672 - 13,679,724 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,649,672 - 13,679,724 (-)Ensemblpanpan1.1panPan2
SEPHS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1223,147,303 - 23,178,808 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl223,146,353 - 23,177,174 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha220,206,289 - 20,234,810 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0223,451,063 - 23,484,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl223,451,285 - 23,483,201 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0221,488,419 - 21,516,923 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0222,116,824 - 22,145,106 (+)NCBIUU_Cfam_GSD_1.0
Sephs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093445,557,754 - 5,584,152 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936613107,821 - 134,733 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936613108,331 - 134,727 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPHS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,348,588 - 13,375,559 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,345,798 - 13,375,536 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605118,879,109 - 18,910,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sephs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248051,851,337 - 1,873,731 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248051,850,796 - 1,878,024 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SEPHS1
542 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 10 4 3 5 2 23 2 3 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000041326   ⟹   ENSSSCP00000035641
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1048,362,463 - 48,386,431 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042678   ⟹   ENSSSCP00000047480
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1048,359,390 - 48,386,263 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000054975   ⟹   ENSSSCP00000038617
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1048,360,954 - 48,385,793 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000071065   ⟹   ENSSSCP00000071448
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1048,360,921 - 48,385,782 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000090041   ⟹   ENSSSCP00000064925
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1048,360,954 - 48,384,139 (+)Ensembl
RefSeq Acc Id: XM_021064859   ⟹   XP_020920518
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11048,359,379 - 48,385,783 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064860   ⟹   XP_020920519
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11048,360,133 - 48,385,787 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021064861   ⟹   XP_020920520
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11048,360,959 - 48,385,787 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_020920518   ⟸   XM_021064859
- UniProtKB: A0A4X1VY11 (UniProtKB/TrEMBL),   K9IVF4 (UniProtKB/TrEMBL),   A0A4X1VZ42 (UniProtKB/TrEMBL),   A0A8D0K2V0 (UniProtKB/TrEMBL),   A0A8D1Z411 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920519   ⟸   XM_021064860
- UniProtKB: A0A4X1VY11 (UniProtKB/TrEMBL),   K9IVF4 (UniProtKB/TrEMBL),   A0A4X1VZ42 (UniProtKB/TrEMBL),   A0A8D0K2V0 (UniProtKB/TrEMBL),   A0A8D1Z411 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_020920520   ⟸   XM_021064861
- UniProtKB: A0A4X1VY11 (UniProtKB/TrEMBL),   K9IVF4 (UniProtKB/TrEMBL),   A0A4X1VZ42 (UniProtKB/TrEMBL),   A0A8D0K2V0 (UniProtKB/TrEMBL),   A0A8D1Z411 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000038617   ⟸   ENSSSCT00000054975
RefSeq Acc Id: ENSSSCP00000064925   ⟸   ENSSSCT00000090041
RefSeq Acc Id: ENSSSCP00000035641   ⟸   ENSSSCT00000041326
RefSeq Acc Id: ENSSSCP00000047480   ⟸   ENSSSCT00000042678
RefSeq Acc Id: ENSSSCP00000071448   ⟸   ENSSSCT00000071065
Protein Domains
PurM-like C-terminal   PurM-like N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000031659 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005032251 UniProtKB/TrEMBL
  ENSSSCG00015036235 UniProtKB/TrEMBL
  ENSSSCG00025054883 UniProtKB/TrEMBL
  ENSSSCG00030030678 UniProtKB/TrEMBL
  ENSSSCG00035043658 UniProtKB/TrEMBL
  ENSSSCG00040058914 UniProtKB/TrEMBL
  ENSSSCG00045033795 UniProtKB/TrEMBL
  ENSSSCG00050058746 UniProtKB/TrEMBL
  ENSSSCG00055003064 UniProtKB/TrEMBL
  ENSSSCG00060009925 UniProtKB/TrEMBL
  ENSSSCG00065049354 UniProtKB/TrEMBL
  ENSSSCG00070027353 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041326 ENTREZGENE
  ENSSSCT00000041326.3 UniProtKB/TrEMBL
  ENSSSCT00005051467.1 UniProtKB/TrEMBL
  ENSSSCT00005051495.1 UniProtKB/TrEMBL
  ENSSSCT00005051554.1 UniProtKB/TrEMBL
  ENSSSCT00015048344.1 UniProtKB/TrEMBL
  ENSSSCT00015048482.1 UniProtKB/TrEMBL
  ENSSSCT00015048681.1 UniProtKB/TrEMBL
  ENSSSCT00015048791.1 UniProtKB/TrEMBL
  ENSSSCT00025075092.1 UniProtKB/TrEMBL
  ENSSSCT00025075235.1 UniProtKB/TrEMBL
  ENSSSCT00025075382.1 UniProtKB/TrEMBL
  ENSSSCT00030042574.1 UniProtKB/TrEMBL
  ENSSSCT00030042605.1 UniProtKB/TrEMBL
  ENSSSCT00030042637.1 UniProtKB/TrEMBL
  ENSSSCT00035058015.1 UniProtKB/TrEMBL
  ENSSSCT00035058018.1 UniProtKB/TrEMBL
  ENSSSCT00035058021.1 UniProtKB/TrEMBL
  ENSSSCT00040080003.1 UniProtKB/TrEMBL
  ENSSSCT00040080060.1 UniProtKB/TrEMBL
  ENSSSCT00045057821.1 UniProtKB/TrEMBL
  ENSSSCT00045057911.1 UniProtKB/TrEMBL
  ENSSSCT00050080053.1 UniProtKB/TrEMBL
  ENSSSCT00050080057.1 UniProtKB/TrEMBL
  ENSSSCT00050080058.1 UniProtKB/TrEMBL
  ENSSSCT00055005933.1 UniProtKB/TrEMBL
  ENSSSCT00055005946.1 UniProtKB/TrEMBL
  ENSSSCT00055005957.1 UniProtKB/TrEMBL
  ENSSSCT00060012834.1 UniProtKB/TrEMBL
  ENSSSCT00060012839.1 UniProtKB/TrEMBL
  ENSSSCT00060012844.1 UniProtKB/TrEMBL
  ENSSSCT00065067572.1 UniProtKB/TrEMBL
  ENSSSCT00065067575.1 UniProtKB/TrEMBL
  ENSSSCT00065067582.1 UniProtKB/TrEMBL
  ENSSSCT00065067586.1 UniProtKB/TrEMBL
  ENSSSCT00070054866.1 UniProtKB/TrEMBL
  ENSSSCT00070054867.1 UniProtKB/TrEMBL
  ENSSSCT00070054868.1 UniProtKB/TrEMBL
  ENSSSCT00070054870.1 UniProtKB/TrEMBL
  ENSSSCT00070054871.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1330.10 UniProtKB/TrEMBL
  3.90.650.10 UniProtKB/TrEMBL
InterPro PurM-like_C_dom UniProtKB/TrEMBL
  PurM-like_C_sf UniProtKB/TrEMBL
  PurM-like_N UniProtKB/TrEMBL
  PurM-like_N_sf UniProtKB/TrEMBL
  SPS/SelD UniProtKB/TrEMBL
NCBI Gene SEPHS1 ENTREZGENE
PANTHER PTHR10256 UniProtKB/TrEMBL
  SELENIDE, WATER DIKINASE 1 UniProtKB/TrEMBL
Pfam AIRS UniProtKB/TrEMBL
  AIRS_C UniProtKB/TrEMBL
PIRSF Selenphspht_syn UniProtKB/TrEMBL
Superfamily-SCOP SSF55326 UniProtKB/TrEMBL
  SSF56042 UniProtKB/TrEMBL
UniProt A0A286ZVF7_PIG UniProtKB/TrEMBL
  A0A4X1VY11 ENTREZGENE
  A0A4X1VY16_PIG UniProtKB/TrEMBL
  A0A4X1VZ42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0K2V0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1N997_PIG UniProtKB/TrEMBL
  A0A8D1Z411 ENTREZGENE, UniProtKB/TrEMBL
  K9IVF4 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A4X1VY11 UniProtKB/TrEMBL
VGNC ID VGNC:104053 ENTREZGENE