Lamp2<sup>em1</sup> (lysosomal-associated membrane protein 2; TALEN induced mutant1) - Rat Genome Database

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Gene: Lamp2em1 (lysosomal-associated membrane protein 2; TALEN induced mutant1) Rattus norvegicus
Analyze
Symbol: Lamp2em1
Name: lysosomal-associated membrane protein 2; TALEN induced mutant1
RGD ID: 13703121
Description: This mutation was generated by injecting TALEN targeting exon 2 of rat Lamp2 into SD embryos. The resulting mutation is a 2-bp deletion.
ASSOCIATED WITH abnormal learning/memory/conditioning; abnormal locomotor behavior; abnormal mitophagy; ASSOCIATED WITH cholestasis; chronic conjunctivitis; cognitive disorder
Type: allele  of Lamp2  
Previously known as: Lamp2^[em1]
Is Marker For: Strains:   SD-Lamp2em1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. Characterisation of Lamp2-deficient rats for potential new animal model of Danon disease. Ma S, etal., Sci Rep. 2018 May 2;8(1):6932. doi: 10.1038/s41598-018-24351-w.
2. A Critical Evaluation of Liver Pathology in Humans with Danon Disease and Experimental Correlates in a Rat Model of LAMP-2 Deficiency. Wang L, etal., Clin Rev Allergy Immunol. 2017 Aug;53(1):105-116. doi: 10.1007/s12016-017-8598-3.

Genomics


Related Rat Strains
The following Strains have been annotated to Lamp2em1
SD-Lamp2em1    


Expression


Sequence

Nucleotide Sequences


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-03 Lamp2em1  lysosomal-associated membrane protein 2; TALEN induced mutant1  Lamp2em1    Name changed 629549 APPROVED