OPRPN (opiorphin prepropeptide) - Rat Genome Database

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Advanced Search (OLGA)
Gene: OPRPN (opiorphin prepropeptide) Homo sapiens
Analyze
Symbol: OPRPN
Name: opiorphin prepropeptide
RGD ID: 1351065
HGNC Page HGNC:17279
Description: Enables endopeptidase inhibitor activity. Involved in regulation of sensory perception of pain. Located in extracellular region.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: basic proline-rich lacrimal protein; basic proline-rich protein; BPLP; opiorphin; PRL1; PROL1; proline rich, lacrimal 1; proline-rich 1; proline-rich protein 1
RGD Orthologs
Mouse
Rat
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38470,397,940 - 70,410,195 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl470,397,931 - 70,410,195 (+)EnsemblGRCh38hg38GRCh38
GRCh37471,263,657 - 71,275,912 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36471,298,188 - 71,310,503 (+)NCBINCBI36Build 36hg18NCBI36
Build 34471,444,452 - 71,456,671NCBI
Celera468,621,402 - 68,633,756 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef467,065,908 - 67,078,224 (+)NCBIHuRef
CHM1_1471,299,691 - 71,312,010 (+)NCBICHM1_1
T2T-CHM13v2.0473,737,473 - 73,749,728 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8670737   PMID:10831095   PMID:12477932   PMID:15851553   PMID:17101991   PMID:18410445   PMID:18855623   PMID:19267851   PMID:19442408   PMID:20438769   PMID:20610867   PMID:20814077  
PMID:21145938   PMID:21624966   PMID:21873635   PMID:22664934   PMID:23580065   PMID:24803544   PMID:24855109   PMID:24900367   PMID:25179084   PMID:27432908   PMID:28514442   PMID:33593085  
PMID:33961781   PMID:35636040  


Genomics

Comparative Map Data
OPRPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38470,397,940 - 70,410,195 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl470,397,931 - 70,410,195 (+)EnsemblGRCh38hg38GRCh38
GRCh37471,263,657 - 71,275,912 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36471,298,188 - 71,310,503 (+)NCBINCBI36Build 36hg18NCBI36
Build 34471,444,452 - 71,456,671NCBI
Celera468,621,402 - 68,633,756 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef467,065,908 - 67,078,224 (+)NCBIHuRef
CHM1_1471,299,691 - 71,312,010 (+)NCBICHM1_1
T2T-CHM13v2.0473,737,473 - 73,749,728 (+)NCBIT2T-CHM13v2.0
Smr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39588,234,415 - 88,256,912 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl588,234,415 - 88,256,912 (+)EnsemblGRCm39 Ensembl
GRCm38588,086,556 - 88,109,053 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl588,086,556 - 88,109,053 (+)EnsemblGRCm38mm10GRCm38
MGSCv37588,515,581 - 88,538,078 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36589,161,117 - 89,183,614 (+)NCBIMGSCv36mm8
Celera586,261,754 - 86,284,251 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map543.56NCBI
Oprpn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81419,986,575 - 20,001,589 (-)NCBIGRCr8
mRatBN7.21419,702,535 - 19,717,550 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1419,702,535 - 19,717,550 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1419,671,787 - 19,685,837 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01420,990,666 - 21,004,716 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01419,713,368 - 19,728,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01421,338,464 - 21,353,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1421,338,601 - 21,352,491 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01421,252,544 - 21,267,613 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41421,294,053 - 21,308,816 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11421,294,394 - 21,294,762 (-)NCBI
Celera1419,038,353 - 19,052,855 (-)NCBICelera
Cytogenetic Map14p22NCBI
OPRPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2359,680,693 - 59,693,006 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1459,875,811 - 59,889,597 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0453,820,177 - 53,833,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1460,165,212 - 60,177,582 (-)NCBIpanpan1.1PanPan1.1panPan2
OPRPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1718,913,378 - 18,925,886 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl718,914,978 - 18,925,760 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660843,974,853 - 3,976,934 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in OPRPN
1 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q13.2-13.3(chr4:66842408-70831557)x1 copy number loss See cases [RCV000050704] Chr4:66842408..70831557 [GRCh38]
Chr4:67708126..71697274 [GRCh37]
Chr4:67390721..71916138 [NCBI36]
Chr4:4q13.2-13.3		 pathogenic
GRCh38/hg38 4q13.3(chr4:70072741-71612174)x3 copy number gain See cases [RCV000051600] Chr4:70072741..71612174 [GRCh38]
Chr4:70938458..72477891 [GRCh37]
Chr4:70973047..72696755 [NCBI36]
Chr4:4q13.3		 uncertain significance
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3		 pathogenic
GRCh38/hg38 4q13.2-21.23(chr4:67869564-85517308)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|See cases [RCV000053294] Chr4:67869564..85517308 [GRCh38]
Chr4:68735282..86438461 [GRCh37]
Chr4:68417877..86657485 [NCBI36]
Chr4:4q13.2-21.23		 pathogenic
GRCh38/hg38 4q13.1-13.3(chr4:65454562-72313693)x1 copy number loss See cases [RCV000053293] Chr4:65454562..72313693 [GRCh38]
Chr4:66320280..73179410 [GRCh37]
Chr4:66002875..73398274 [NCBI36]
Chr4:4q13.1-13.3		 pathogenic
GRCh38/hg38 4q13.3(chr4:70297081-70405653)x1 copy number loss See cases [RCV000135706] Chr4:70297081..70405653 [GRCh38]
Chr4:71162798..71271370 [GRCh37]
Chr4:71197387..71305959 [NCBI36]
Chr4:4q13.3		 uncertain significance|conflicting data from submitters
GRCh38/hg38 4q13.2-13.3(chr4:68902161-70620273)x3 copy number gain See cases [RCV000136751] Chr4:68902161..70620273 [GRCh38]
Chr4:69767879..71485990 [GRCh37]
Chr4:69802468..71520579 [NCBI36]
Chr4:4q13.2-13.3		 pathogenic
GRCh38/hg38 4q13.2-13.3(chr4:67799665-74240920)x1 copy number loss See cases [RCV000137622] Chr4:67799665..74240920 [GRCh38]
Chr4:68665383..75106637 [GRCh37]
Chr4:68347978..75325501 [NCBI36]
Chr4:4q13.2-13.3		 likely pathogenic
GRCh38/hg38 4q13.3(chr4:70054775-70478053)x1 copy number loss See cases [RCV000137929] Chr4:70054775..70478053 [GRCh38]
Chr4:70920492..71343770 [GRCh37]
Chr4:70955081..71378359 [NCBI36]
Chr4:4q13.3		 likely benign|uncertain significance
GRCh38/hg38 4q13.3(chr4:70204468-71204531)x3 copy number gain See cases [RCV000143430] Chr4:70204468..71204531 [GRCh38]
Chr4:71070185..72070248 [GRCh37]
Chr4:71104774..72289112 [NCBI36]
Chr4:4q13.3		 uncertain significance
GRCh38/hg38 4q13.2-22.3(chr4:68686088-95294456)x3 copy number gain See cases [RCV000143458] Chr4:68686088..95294456 [GRCh38]
Chr4:69551806..96215607 [GRCh37]
Chr4:69234401..96434630 [NCBI36]
Chr4:4q13.2-22.3		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.3(chr4:71200989-71275284)x1 copy number loss See cases [RCV000448122] Chr4:71200989..71275284 [GRCh37]
Chr4:4q13.3		 likely benign
GRCh37/hg19 4q13.1-21.1(chr4:66017575-76772947)x1 copy number loss See cases [RCV000510445] Chr4:66017575..76772947 [GRCh37]
Chr4:4q13.1-21.1		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:64705501-73469716)x3 copy number gain not provided [RCV000682409] Chr4:64705501..73469716 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q12-13.3(chr4:58332294-71587615)x1 copy number loss not provided [RCV000743602] Chr4:58332294..71587615 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.3(chr4:71165491-71272547)x1 copy number loss not provided [RCV000743698] Chr4:71165491..71272547 [GRCh37]
Chr4:4q13.3		 benign
GRCh37/hg19 4q13.3(chr4:71165491-71276077)x1 copy number loss not provided [RCV000743699] Chr4:71165491..71276077 [GRCh37]
Chr4:4q13.3		 benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2		 pathogenic
GRCh37/hg19 4q13.3(chr4:70929700-72479262)x3 copy number gain not provided [RCV000849565] Chr4:70929700..72479262 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.2-21.22(chr4:68242784-82991431)x3 copy number gain not provided [RCV000845944] Chr4:68242784..82991431 [GRCh37]
Chr4:4q13.2-21.22		 pathogenic
GRCh37/hg19 4q13.3(chr4:71193683-71591539)x3 copy number gain not provided [RCV001005555] Chr4:71193683..71591539 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.2-21.21(chr4:68950363-79738598)x1 copy number loss not provided [RCV001005553] Chr4:68950363..79738598 [GRCh37]
Chr4:4q13.2-21.21		 pathogenic
GRCh38/hg38 4q12-21.1(chr4:51891814-76009719)x1 copy number loss Piebaldism [RCV001420508] Chr4:51891814..76009719 [GRCh38]
Chr4:4q12-21.1		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:61867555-74711517) copy number loss not specified [RCV002053422] Chr4:61867555..74711517 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21		 pathogenic
NC_000004.12:g.67833055_82716065del deletion See cases [RCV003313802] Chr4:67833055..82716065 [GRCh38]
Chr4:4q13.2-21.22		 pathogenic
NM_021225.5(OPRPN):c.199C>A (p.Pro67Thr) single nucleotide variant not specified [RCV004247107] Chr4:70409527 [GRCh38]
Chr4:71275244 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q12-13.3(chr4:57584845-72430996)x1 copy number loss not provided [RCV003485417] Chr4:57584845..72430996 [GRCh37]
Chr4:4q12-13.3		 pathogenic
GRCh37/hg19 4q13.2-13.3(chr4:69146217-75500577)x1 copy number loss not provided [RCV003485422] Chr4:69146217..75500577 [GRCh37]
Chr4:4q13.2-13.3		 pathogenic
GRCh37/hg19 4q13.1-13.3(chr4:63684557-71480358)x3 copy number gain not provided [RCV003484182] Chr4:63684557..71480358 [GRCh37]
Chr4:4q13.1-13.3		 pathogenic
GRCh37/hg19 4q13.3(chr4:71271311-71502766)x1 copy number loss See cases [RCV003482183] Chr4:71271311..71502766 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4q13.3(chr4:71132998-72479262)x3 copy number gain not specified [RCV003986498] Chr4:71132998..72479262 [GRCh37]
Chr4:4q13.3		 uncertain significance
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:382
Count of miRNA genes:237
Interacting mature miRNAs:239
Transcripts:ENST00000399575, ENST00000505023, ENST00000514338
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407127864GWAS776840_HC-X-C motif chemokine 10 measurement QTL GWAS776840 (human)1e-13C-X-C motif chemokine 10 measurement47040410670404107Human

Markers in Region
SHGC-67981  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37471,275,674 - 71,275,871UniSTSGRCh37
Build 36471,310,263 - 71,310,460RGDNCBI36
Celera468,633,512 - 68,633,709RGD
Cytogenetic Map4q13.3UniSTS
HuRef467,077,984 - 67,078,181UniSTS
TNG Radiation Hybrid Map438849.0UniSTS
GeneMap99-GB4 RH Map4407.22UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
105 191 716 157 1172 513 549 473 210 320 950 926 600 282 1 76 556 179 152 1

Sequence


Ensembl Acc Id: ENST00000399575   ⟹   ENSP00000382485
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl470,397,940 - 70,410,195 (+)Ensembl
Ensembl Acc Id: ENST00000505023
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl470,397,965 - 70,409,908 (+)Ensembl
Ensembl Acc Id: ENST00000514338
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl470,397,931 - 70,409,892 (+)Ensembl
RefSeq Acc Id: NM_001302807   ⟹   NP_001289736
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38470,397,940 - 70,410,195 (+)NCBI
CHM1_1471,299,691 - 71,312,010 (+)NCBI
T2T-CHM13v2.0473,737,473 - 73,749,728 (+)NCBI
Sequence:
RefSeq Acc Id: NM_021225   ⟹   NP_067048
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38470,397,940 - 70,410,195 (+)NCBI
GRCh37471,263,599 - 71,275,914 (+)RGD
Build 36471,298,188 - 71,310,503 (+)NCBI Archive
Celera468,621,402 - 68,633,756 (+)RGD
HuRef467,065,908 - 67,078,224 (+)RGD
CHM1_1471,299,691 - 71,312,010 (+)NCBI
T2T-CHM13v2.0473,737,473 - 73,749,728 (+)NCBI
Sequence:
RefSeq Acc Id: NR_126503
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38470,397,940 - 70,410,195 (+)NCBI
CHM1_1471,299,691 - 71,312,010 (+)NCBI
T2T-CHM13v2.0473,737,473 - 73,749,728 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001289736 (Get FASTA)   NCBI Sequence Viewer  
  NP_067048 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB46823 (Get FASTA)   NCBI Sequence Viewer  
  CAJ32190 (Get FASTA)   NCBI Sequence Viewer  
  CAJ34589 (Get FASTA)   NCBI Sequence Viewer  
  EAX05620 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000382485
  ENSP00000382485.2
GenBank Protein Q99935 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_067048   ⟸   NM_021225
- Peptide Label: isoform 1 precursor
- UniProtKB: A8MZ07 (UniProtKB/Swiss-Prot),   P85047 (UniProtKB/Swiss-Prot),   Q99935 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001289736   ⟸   NM_001302807
- Peptide Label: isoform 2 precursor
- Sequence:
Ensembl Acc Id: ENSP00000382485   ⟸   ENST00000399575

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99935-F1-model_v2 AlphaFold Q99935 1-248 view protein structure

Promoters
RGD ID:6867638
Promoter ID:EPDNEW_H6984
Type:multiple initiation site
Name:OPRPN_1
Description:opiorphin prepropeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38470,397,940 - 70,398,000EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:17279 AgrOrtholog
COSMIC OPRPN COSMIC
Ensembl Genes ENSG00000171199 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000399575 ENTREZGENE
  ENST00000399575.7 UniProtKB/Swiss-Prot
GTEx ENSG00000171199 GTEx
HGNC ID HGNC:17279 ENTREZGENE
Human Proteome Map OPRPN Human Proteome Map
InterPro SMR-like UniProtKB/Swiss-Prot
KEGG Report hsa:58503 UniProtKB/Swiss-Prot
NCBI Gene 58503 ENTREZGENE
OMIM 608936 OMIM
PANTHER OPIORPHIN PREPROPEPTIDE UniProtKB/Swiss-Prot
  PTHR14179 UniProtKB/Swiss-Prot
Pfam PROL5-SMR UniProtKB/Swiss-Prot
PharmGKB PA33803 PharmGKB
UniProt A8MZ07 ENTREZGENE
  P85047 ENTREZGENE
  PROL1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A8MZ07 UniProtKB/Swiss-Prot
  P85047 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 OPRPN  opiorphin prepropeptide  PROL1  proline rich, lacrimal 1  Symbol and/or name change 5135510 APPROVED