LINC02901 (long intergenic non-protein coding RNA 2901) - Rat Genome Database

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Gene: LINC02901 (long intergenic non-protein coding RNA 2901) Homo sapiens
Analyze
Symbol: LINC02901
Name: long intergenic non-protein coding RNA 2901
RGD ID: 1350961
HGNC Page HGNC:21179
Description: ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome; chromosome 6q24-q25 deletion syndrome; primary ciliary dyskinesia 32; INTERACTS WITH 2-hydroxypropanoic acid; benzo[a]pyrene; cisplatin
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: C6orf99; chromosome 6 open reading frame 99; chromosome 6 putative open reading frame 99; putative uncharacterized protein C6orf99; yR211F11.1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,869,814 - 158,910,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,869,848 - 158,919,105 (+)EnsemblGRCh38hg38GRCh38
GRCh376159,290,846 - 159,331,385 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366159,210,965 - 159,251,373 (+)NCBINCBI36Build 36hg18NCBI36
Celera6159,957,470 - 159,979,248 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,780,799 - 156,802,469 (+)NCBIHuRef
CHM1_16159,572,158 - 159,593,934 (+)NCBICHM1_1
T2T-CHM13v2.06160,115,224 - 160,155,759 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14574404   PMID:16344560   PMID:29676528  


Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q24.1-27(chr6:141132990-169339571)x3 copy number gain See cases [RCV000050604] Chr6:141132990..169339571 [GRCh38]
Chr6:141454127..169739666 [GRCh37]
Chr6:141495820..169481591 [NCBI36]
Chr6:6q24.1-27
pathogenic
GRCh38/hg38 6q25.2-27(chr6:152376338-170583214)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051902]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051902]|See cases [RCV000051902] Chr6:152376338..170583214 [GRCh38]
Chr6:152697473..170892302 [GRCh37]
Chr6:152739166..170734227 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.3(chr6:157827805-159726548)x3 copy number gain See cases [RCV000051903] Chr6:157827805..159726548 [GRCh38]
Chr6:158248837..160147580 [GRCh37]
Chr6:158168825..160067570 [NCBI36]
Chr6:6q25.3
pathogenic
GRCh38/hg38 6q25.3-27(chr6:158664768-170612001)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051904]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051904]|See cases [RCV000051904] Chr6:158664768..170612001 [GRCh38]
Chr6:159085800..170921089 [GRCh37]
Chr6:159005788..170763014 [NCBI36]
Chr6:6q25.3-27
pathogenic
GRCh38/hg38 6q25.2-27(chr6:154118058-170602152)x1 copy number loss See cases [RCV000052207] Chr6:154118058..170602152 [GRCh38]
Chr6:154439193..170911240 [GRCh37]
Chr6:154480885..170753165 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.2-25.3(chr6:154178964-159020369)x1 copy number loss See cases [RCV000134896] Chr6:154178964..159020369 [GRCh38]
Chr6:154500098..159441401 [GRCh37]
Chr6:154541790..159361389 [NCBI36]
Chr6:6q25.2-25.3
likely pathogenic
GRCh38/hg38 6q25.2-27(chr6:154539655-170714507)x1 copy number loss See cases [RCV000137381] Chr6:154539655..170714507 [GRCh38]
Chr6:154860789..171023595 [GRCh37]
Chr6:154902481..170865520 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.3-26(chr6:155378049-163133499)x1 copy number loss See cases [RCV000137831] Chr6:155378049..163133499 [GRCh38]
Chr6:155699183..163554531 [GRCh37]
Chr6:155740875..163474521 [NCBI36]
Chr6:6q25.3-26
pathogenic
GRCh38/hg38 6q25.1-25.3(chr6:150381239-159553952)x1 copy number loss See cases [RCV000139578] Chr6:150381239..159553952 [GRCh38]
Chr6:150702375..159974984 [GRCh37]
Chr6:150744068..159894974 [NCBI36]
Chr6:6q25.1-25.3
pathogenic
GRCh38/hg38 6q25.2-27(chr6:152793402-170610394)x1 copy number loss See cases [RCV000141880] Chr6:152793402..170610394 [GRCh38]
Chr6:153114537..170919482 [GRCh37]
Chr6:153156230..170761407 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q25.2-27(chr6:152376338-170612001)x3 copy number gain See cases [RCV000142594] Chr6:152376338..170612001 [GRCh38]
Chr6:152697473..170921089 [GRCh37]
Chr6:152739166..170763014 [NCBI36]
Chr6:6q25.2-27
pathogenic
GRCh38/hg38 6q23.2-27(chr6:133537271-165875545)x3 copy number gain See cases [RCV000143444] Chr6:133537271..165875545 [GRCh38]
Chr6:133858409..166289033 [GRCh37]
Chr6:133900102..166209023 [NCBI36]
Chr6:6q23.2-27
pathogenic
GRCh38/hg38 6q25.3-26(chr6:158585724-160899783)x3 copy number gain See cases [RCV000143618] Chr6:158585724..160899783 [GRCh38]
Chr6:159006756..161320815 [GRCh37]
Chr6:158926744..161240805 [NCBI36]
Chr6:6q25.3-26
uncertain significance
GRCh37/hg19 6q25.1-27(chr6:151214792-170892243)x3 copy number gain See cases [RCV000449011] Chr6:151214792..170892243 [GRCh37]
Chr6:6q25.1-27
pathogenic
GRCh37/hg19 6q25.3(chr6:155525920-159889169)x1 copy number loss See cases [RCV000447692] Chr6:155525920..159889169 [GRCh37]
Chr6:6q25.3
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
46,XX,der(6)(q25.1,q28)dn.seq[GRCh37/hg19]der(6)(6pter->6q25.2(+)(154768571)::q25.2(+)(154778901),q25.2(+)154778992::q25.2(-)(154774048),q25.2(-)(154768571)::q25.2(-)(154768571),q25.1(-)(~151443183-151443483))dn complex Coffin-Siris syndrome 1 [RCV000714957] Chr6:151443333..171115067 [GRCh37]
Chr6:6q25.1-27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q25.1-27(chr6:150284435-170919470)x3 copy number gain not provided [RCV000746100] Chr6:150284435..170919470 [GRCh37]
Chr6:6q25.1-27
pathogenic
GRCh37/hg19 6q25.3-27(chr6:159155998-171054786)x3 copy number gain not provided [RCV000746132] Chr6:159155998..171054786 [GRCh37]
Chr6:6q25.3-27
pathogenic
GRCh37/hg19 6q25.3-27(chr6:159006336-170713678)x3 copy number gain not provided [RCV003312672] Chr6:159006336..170713678 [GRCh37]
Chr6:6q25.3-27
uncertain significance
GRCh37/hg19 6q25.3(chr6:157262571-160992289)x3 copy number gain not provided [RCV000848057] Chr6:157262571..160992289 [GRCh37]
Chr6:6q25.3
uncertain significance
GRCh37/hg19 6q24.3-25.3(chr6:148195086-160127254)x3 copy number gain not provided [RCV000846496] Chr6:148195086..160127254 [GRCh37]
Chr6:6q24.3-25.3
pathogenic
GRCh37/hg19 6q25.2-26(chr6:153207930-164322346) copy number loss not specified [RCV002053640] Chr6:153207930..164322346 [GRCh37]
Chr6:6q25.2-26
pathogenic
GRCh37/hg19 6q25.3(chr6:155525920-159889169) copy number loss not specified [RCV002053642] Chr6:155525920..159889169 [GRCh37]
Chr6:6q25.3
pathogenic
NC_000006.11:g.(?_158532398)_(160114199_?)dup duplication Primary ciliary dyskinesia 32 [RCV001934131] Chr6:158532398..160114199 [GRCh37]
Chr6:6q25.3
uncertain significance
NC_000006.11:g.(?_158532398)_(162868359_?)del deletion 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome [RCV003122912]|not provided [RCV003122911] Chr6:158532398..162868359 [GRCh37]
Chr6:6q25.3-26
pathogenic|no classifications from unflagged records
GRCh37/hg19 6q25.3-27(chr6:159121459-170919482) copy number loss Hydrocephalus [RCV002280751] Chr6:159121459..170919482 [GRCh37]
Chr6:6q25.3-27
pathogenic
GRCh37/hg19 6q25.3-27(chr6:157318401-165233548)x1 copy number loss See cases [RCV002287557] Chr6:157318401..165233548 [GRCh37]
Chr6:6q25.3-27
pathogenic
GRCh37/hg19 6q25.2-27(chr6:152853218-170914297)x1 copy number loss See cases [RCV004442824] Chr6:152853218..170914297 [GRCh37]
Chr6:6q25.2-27
pathogenic
NC_000006.12:g.(?_150381239)_(159553952_?)del deletion Chromosome 6q24-q25 deletion syndrome [RCV003884000] Chr6:150381239..159553952 [GRCh38]
Chr6:6q25.1-25.3
pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:228
Count of miRNA genes:116
Interacting mature miRNAs:117
Transcripts:ENST00000367072, ENST00000367073, ENST00000486232, ENST00000608817
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH99275  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,331,023 - 159,331,183UniSTSGRCh37
Build 366159,251,011 - 159,251,171RGDNCBI36
Celera6159,978,886 - 159,979,046RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,802,107 - 156,802,267UniSTS
GeneMap99-GB4 RH Map6621.65UniSTS
SHGC-57156  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376159,331,073 - 159,331,221UniSTSGRCh37
Build 366159,251,061 - 159,251,209RGDNCBI36
Celera6159,978,936 - 159,979,084RGD
Cytogenetic Map6q25.3UniSTS
HuRef6156,802,157 - 156,802,305UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 16 8 3 26 5 4 4 10 399 53 1
Low 579 62 785 159 717 131 1111 113 815 300 420 783 36 77 476 4
Below cutoff 1435 1702 799 366 916 241 2027 1304 2366 96 481 700 126 742 1415 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_160976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_160982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA913820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL627422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW138390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF688381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB080574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB455167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY021938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY052980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY205185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OA988731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W37337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000367072
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,910 - 158,910,350 (+)Ensembl
RefSeq Acc Id: ENST00000367073
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,853 - 158,910,353 (+)Ensembl
RefSeq Acc Id: ENST00000486232
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,851 - 158,910,353 (+)Ensembl
RefSeq Acc Id: ENST00000608817
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,895,217 - 158,910,352 (+)Ensembl
RefSeq Acc Id: ENST00000643288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,867 - 158,919,105 (+)Ensembl
RefSeq Acc Id: ENST00000650421
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,852 - 158,910,402 (+)Ensembl
RefSeq Acc Id: ENST00000653976
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,854 - 158,910,364 (+)Ensembl
RefSeq Acc Id: ENST00000654049
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,848 - 158,910,351 (+)Ensembl
RefSeq Acc Id: ENST00000655791
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,867 - 158,910,351 (+)Ensembl
RefSeq Acc Id: ENST00000658761
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,910 - 158,910,347 (+)Ensembl
RefSeq Acc Id: ENST00000659187
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,855 - 158,910,353 (+)Ensembl
RefSeq Acc Id: ENST00000663340
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,899 - 158,910,351 (+)Ensembl
RefSeq Acc Id: ENST00000663769
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,855 - 158,910,353 (+)Ensembl
RefSeq Acc Id: ENST00000663950
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,867 - 158,910,347 (+)Ensembl
RefSeq Acc Id: ENST00000666927
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,854 - 158,910,351 (+)Ensembl
RefSeq Acc Id: ENST00000686607
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,939 - 158,910,350 (+)Ensembl
RefSeq Acc Id: ENST00000692856
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,888 - 158,910,349 (+)Ensembl
RefSeq Acc Id: ENST00000693135
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,934 - 158,910,387 (+)Ensembl
RefSeq Acc Id: ENST00000700908
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6158,869,906 - 158,919,054 (+)Ensembl
RefSeq Acc Id: NR_160976
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,870,029 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,439 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160977
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,869,814 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,224 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160978
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,869,814 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,224 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160979
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,888,477 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,133,888 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160980
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,869,814 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,224 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160981
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,870,029 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,439 - 160,155,759 (+)NCBI
Sequence:
RefSeq Acc Id: NR_160982
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386158,870,029 - 158,910,353 (+)NCBI
T2T-CHM13v2.06160,115,439 - 160,155,759 (+)NCBI
Sequence:
Protein Sequences
GenBank Protein Q4VX62 (Get FASTA)   NCBI Sequence Viewer  

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4VX62-F1-model_v2 AlphaFold Q4VX62 1-202 view protein structure

Promoters
RGD ID:6803877
Promoter ID:HG_KWN:55631
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000367072,   OTTHUMT00000042886
Position:
Human AssemblyChrPosition (strand)Source
Build 366159,210,406 - 159,211,182 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
COSMIC LINC02901 COSMIC
Ensembl Genes ENSG00000203711 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000486232 ENTREZGENE
  ENST00000650421 ENTREZGENE
  ENST00000653976 ENTREZGENE
  ENST00000655791 ENTREZGENE
  ENST00000663340 ENTREZGENE
  ENST00000666927 ENTREZGENE
GTEx ENSG00000203711 GTEx
HGNC ID HGNC:21179 ENTREZGENE
Human Proteome Map LINC02901 Human Proteome Map
NCBI Gene 100130967 ENTREZGENE
RNAcentral URS0000E60A50 RNACentral
  URS0000E60A66 RNACentral
  URS0000E60A81 RNACentral
  URS0000E60AFD RNACentral
  URS0000E60B03 RNACentral
  URS0000E60B0F RNACentral
  URS0000E60B4E RNACentral
UniProt CF099_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q4VX61 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-15 LINC02901  long intergenic non-protein coding RNA 2901  C6orf99  chromosome 6 putative open reading frame 99  Symbol and/or name change 19259463 PROVISIONAL
2020-08-10 C6orf99  chromosome 6 putative open reading frame 99  C6orf99  chromosome 6 open reading frame 99  Symbol and/or name change 19259463 PROVISIONAL