SPACA6 (sperm acrosome associated 6) - Rat Genome Database

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Gene: SPACA6 (sperm acrosome associated 6) Canis lupus familiaris
Analyze
Symbol: SPACA6
Name: sperm acrosome associated 6
RGD ID: 13275868
Description: INVOLVED IN fusion of sperm to egg plasma membrane involved in single fertilization (ortholog); FOUND IN acrosomal vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sperm acrosome membrane-associated protein 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,386,924 - 105,400,071 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,391,428 - 105,400,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1104,957,360 - 104,973,584 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01105,893,759 - 105,910,244 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1105,901,344 - 105,909,988 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,565,992 - 105,582,220 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,207,096 - 105,223,336 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,001,882 - 106,018,111 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SPACA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11105,386,924 - 105,400,071 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1105,391,428 - 105,400,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1104,957,360 - 104,973,584 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01105,893,759 - 105,910,244 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1105,901,344 - 105,909,988 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11105,565,992 - 105,582,220 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01105,207,096 - 105,223,336 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01106,001,882 - 106,018,111 (-)NCBIUU_Cfam_GSD_1.0
SPACA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381951,682,686 - 51,713,143 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1951,688,346 - 51,712,387 (+)EnsemblGRCh38hg38GRCh38
GRCh371952,192,635 - 52,208,443 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361956,888,592 - 56,900,255 (+)NCBINCBI36Build 36hg18NCBI36
Celera1949,246,128 - 49,257,979 (+)NCBICelera
Cytogenetic Map19q13.41NCBI
HuRef1948,527,534 - 48,539,384 (+)NCBIHuRef
CHM1_11952,198,390 - 52,210,241 (+)NCBICHM1_1
T2T-CHM13v2.01954,769,841 - 54,800,507 (+)NCBIT2T-CHM13v2.0
Spaca6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391718,045,955 - 18,063,274 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1718,047,420 - 18,063,271 (+)EnsemblGRCm39 Ensembl
GRCm381717,826,085 - 17,843,010 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1717,827,158 - 17,843,009 (+)EnsemblGRCm38mm10GRCm38
MGSCv371717,967,939 - 17,976,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361717,535,682 - 17,547,627 (+)NCBIMGSCv36mm8
Celera1718,771,626 - 18,779,754 (+)NCBICelera
Cytogenetic Map17A3.2NCBI
cM Map1710.5NCBI
Spaca6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,345,996 - 67,365,210 (+)NCBIGRCr8
mRatBN7.2158,672,128 - 58,689,309 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl158,677,797 - 58,688,562 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx163,502,385 - 63,513,167 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,195,049 - 72,205,800 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,412,431 - 65,423,213 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0159,700,578 - 59,719,359 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl159,704,998 - 59,715,763 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0160,620,393 - 60,639,020 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4156,487,751 - 56,498,516 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera154,858,755 - 54,869,507 (+)NCBICelera
Cytogenetic Map1q12NCBI
SPACA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22057,732,111 - 57,756,596 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11959,652,351 - 59,680,872 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01948,632,681 - 48,656,124 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11957,513,910 - 57,529,817 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1957,517,865 - 57,529,817 (+)Ensemblpanpan1.1panPan2
Spaca6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093494,780,414 - 4,789,940 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004937026110,793 - 120,301 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPACA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1644,518,271 - 44,533,328 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607324,574,382 - 24,587,569 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spaca6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248323,342,155 - 3,355,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248323,340,420 - 3,354,076 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SPACA6
118 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 1 6 7 8 10 1
Low 5 5 6 6 5 6 4 5 5
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022427975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022427980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038467292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038467293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038527982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038592275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038592276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038653540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038656071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002633424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005320847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005354483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005389065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005422024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005422025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000043610   ⟹   ENSCAFP00000037051
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1105,391,428 - 105,400,071 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845008679   ⟹   ENSCAFP00845006848
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1105,901,344 - 105,909,988 (-)Ensembl
RefSeq Acc Id: XM_022427980   ⟹   XP_022283688
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11105,386,924 - 105,400,071 (-)NCBI
Dog10K_Boxer_Tasha1104,960,399 - 104,973,584 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038467292   ⟹   XP_038323220
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11105,569,033 - 105,582,220 (-)NCBI
RefSeq Acc Id: XM_038467293   ⟹   XP_038323221
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11105,565,992 - 105,582,220 (-)NCBI
RefSeq Acc Id: XM_038527981   ⟹   XP_038383909
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01106,004,923 - 106,018,111 (-)NCBI
RefSeq Acc Id: XM_038527982   ⟹   XP_038383910
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01106,001,882 - 106,018,111 (-)NCBI
RefSeq Acc Id: XM_038592275   ⟹   XP_038448203
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01105,209,930 - 105,223,336 (-)NCBI
RefSeq Acc Id: XM_038592276   ⟹   XP_038448204
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01105,207,096 - 105,223,336 (-)NCBI
RefSeq Acc Id: XM_038653540   ⟹   XP_038509468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1104,957,360 - 104,973,584 (-)NCBI
RefSeq Acc Id: XM_038656067   ⟹   XP_038511995
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,910,244 (-)NCBI
RefSeq Acc Id: XM_038656068   ⟹   XP_038511996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,909,988 (-)NCBI
RefSeq Acc Id: XM_038656069   ⟹   XP_038511997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,893,759 - 105,909,988 (-)NCBI
RefSeq Acc Id: XM_038656070   ⟹   XP_038511998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,910,244 (-)NCBI
RefSeq Acc Id: XM_038656071   ⟹   XP_038511999
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,910,244 (-)NCBI
RefSeq Acc Id: XR_002633424
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11105,386,924 - 105,394,112 (-)NCBI
Dog10K_Boxer_Tasha1104,960,399 - 104,967,538 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005320847
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11105,569,033 - 105,576,166 (-)NCBI
RefSeq Acc Id: XR_005354483
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01106,004,923 - 106,012,062 (-)NCBI
RefSeq Acc Id: XR_005389065
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01105,209,930 - 105,217,284 (-)NCBI
RefSeq Acc Id: XR_005422024
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,910,244 (-)NCBI
RefSeq Acc Id: XR_005422025
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01105,896,801 - 105,903,940 (-)NCBI
RefSeq Acc Id: XP_022283688   ⟸   XM_022427980
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL),   A0A8C0L366 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000037051   ⟸   ENSCAFT00000043610
RefSeq Acc Id: XP_038323221   ⟸   XM_038467293
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038323220   ⟸   XM_038467292
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448204   ⟸   XM_038592276
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038448203   ⟸   XM_038592275
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038511997   ⟸   XM_038656069
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL),   A0A8C0L366 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511999   ⟸   XM_038656071
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038511998   ⟸   XM_038656070
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L366 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511995   ⟸   XM_038656067
- Peptide Label: isoform X2
- UniProtKB: A0A8C0L366 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038511996   ⟸   XM_038656068
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL),   A0A8C0L366 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038509468   ⟸   XM_038653540
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL),   A0A8C0L366 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383910   ⟸   XM_038527982
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L366 (UniProtKB/TrEMBL),   A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383909   ⟸   XM_038527981
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L366 (UniProtKB/TrEMBL),   A0A8C0LVL5 (UniProtKB/TrEMBL),   A0A8I3MMA1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845006848   ⟸   ENSCAFT00845008679
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002820 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000114 UniProtKB/TrEMBL
  ENSCAFG00040001983 UniProtKB/TrEMBL
  ENSCAFG00845004847 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000043610.4 UniProtKB/TrEMBL
  ENSCAFT00030000155.1 UniProtKB/TrEMBL
  ENSCAFT00040003755.1 UniProtKB/TrEMBL
  ENSCAFT00845008679 ENTREZGENE
  ENSCAFT00845008679.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  SPACA6 UniProtKB/TrEMBL
NCBI Gene SPACA6 ENTREZGENE
PANTHER PTHR37366 UniProtKB/TrEMBL
  SPERM ACROSOME MEMBRANE-ASSOCIATED PROTEIN 6 UniProtKB/TrEMBL
Pfam PF00047 UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8C0L366 ENTREZGENE
  A0A8C0LVL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MMA1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53990 ENTREZGENE