Gm53191 (predicted gene, 53191) - Rat Genome Database

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Gene: Gm53191 (predicted gene, 53191) Mus musculus
Analyze
Symbol: Gm53191 (Ensembl: Atrip)
Name: predicted gene, 53191 (Ensembl:ATR interacting protein)
RGD ID: 1323749
MGI Page MGI
Description: This gene represents naturally occurring read-through transcription between adjacent genes Atrip (ATR-interacting protein) and Trex1 (three-prime repair exonuclease 1). The read-through transcript does not encode a protein. [provided by RefSeq, Jan 2018]
Type: ncrna (Ensembl: protein-coding)
RefSeq Status: VALIDATED
Previously known as: 6620401K05Rik; ATM and Rad3 related interacting protein; ATM and Rad3-related-interacting protein; ATR-interacting protein; Atrip; Atrip-trex1; Atrip-Trex1 readthrough; MGC90531
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,887,001 - 108,903,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,887,001 - 108,903,192 (-)EnsemblGRCm39 Ensembl
GRCm389109,057,933 - 109,074,097 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9109,057,933 - 109,074,124 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,962,261 - 108,976,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,917,155 - 108,931,517 (-)NCBIMGSCv36mm8
Celera9108,618,529 - 108,632,920 (-)NCBICelera
Cytogenetic Map9F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
aflatoxin B1  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ATR and ATRIP: partners in checkpoint signaling. Cortez D, etal., Science. 2001 Nov 23;294(5547):1713-6.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Gm53191
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,887,001 - 108,903,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,887,001 - 108,903,192 (-)EnsemblGRCm39 Ensembl
GRCm389109,057,933 - 109,074,097 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9109,057,933 - 109,074,124 (-)EnsemblGRCm38mm10GRCm38
MGSCv379108,962,261 - 108,976,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369108,917,155 - 108,931,517 (-)NCBIMGSCv36mm8
Celera9108,618,529 - 108,632,920 (-)NCBICelera
Cytogenetic Map9F2NCBI
ATRIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,446,779 - 48,467,645 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,446,710 - 48,467,645 (+)EnsemblGRCh38hg38GRCh38
GRCh37348,488,183 - 48,509,044 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,463,222 - 48,482,058 (+)NCBINCBI36Build 36hg18NCBI36
Celera348,438,989 - 48,457,913 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,542,265 - 48,561,084 (+)NCBIHuRef
CHM1_1348,440,399 - 48,459,354 (+)NCBICHM1_1
T2T-CHM13v2.0348,474,787 - 48,495,650 (+)NCBIT2T-CHM13v2.0
Atrip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,586,909 - 118,600,975 (-)NCBIGRCr8
mRatBN7.28109,708,440 - 109,722,511 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,708,440 - 109,722,477 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8115,323,329 - 115,337,354 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,522,503 - 113,536,528 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,365,310 - 111,379,335 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,797,954 - 117,811,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,797,842 - 117,811,975 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08117,149,699 - 117,163,734 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,073,321 - 114,087,356 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera8108,999,733 - 109,013,768 (-)NCBICelera
Cytogenetic Map8q32NCBI
Atrip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532516,753 - 533,498 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955532516,772 - 533,774 (+)NCBIChiLan1.0ChiLan1.0
ATRIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,421,608 - 48,440,530 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,426,376 - 48,445,271 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,368,775 - 48,387,698 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,450,861 - 49,469,351 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,450,991 - 49,469,351 (+)Ensemblpanpan1.1panPan2
Atrip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,484,606 - 63,503,959 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529245,092 - 264,351 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936529245,134 - 264,456 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATRIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,159,843 - 31,178,715 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11331,159,849 - 31,178,716 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,563,866 - 34,575,045 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATRIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1229,849,439 - 9,869,654 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl229,849,570 - 9,869,553 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041157,221,552 - 157,242,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atrip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,413,014 - 2,430,827 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247302,413,474 - 2,431,012 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2771
Count of miRNA genes:715
Interacting mature miRNAs:938
Transcripts:ENSMUST00000045011, ENSMUST00000159614, ENSMUST00000160217, ENSMUST00000160928, ENSMUST00000161163, ENSMUST00000161270, ENSMUST00000161521
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989440541123440541Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989289476123289595Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9101829255124359700Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991560372124359700Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989162124123162124Mouse
1357657Pymr_mPlasmodium yoelli malaria resistance (mouse)Not determined989859058118767089Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103118511124359700Mouse
14746992Manh67_mmandible shape 67 (mouse)993865836124359700Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103118511124359700Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103118511124359700Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993591658124359700Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9100889929124359700Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996746658124359700Mouse
11081166Psl5_mpromotion susceptibility QTL 5 (mouse)994863354112701997Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991560372124359700Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9101829255124359700Mouse
12910773Splic3_mspleen iron content 3 (mouse)991291078124359700Mouse
12910772Lvic6_mliver iron content 6 (mouse)991291078124359700Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991518283124359700Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
12910770Splic1_mspleen iron content 1 (mouse)991291078124359700Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991560372124359700Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991518283124359700Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991518283124359700Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991518283124359700Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
13515058Adip20d_madiposity 20d (mouse)9108744078118744078Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991518283124359700Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991518283124359700Mouse
1301484Bwq6_mbody weight (mouse)Not determined993591658124359700Mouse


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_153412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC140383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NR_153412
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399108,887,001 - 108,903,165 (-)NCBI
GRCm389109,057,933 - 109,074,097 (-)NCBI
Sequence:
Promoters
RGD ID:6844013
Promoter ID:MM_KWN:58852
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000084784,   UC009RRT.1,   UC009RRU.1,   UC009RRV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369108,976,451 - 108,976,951 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1925349 AgrOrtholog
Ensembl Genes ENSMUSG00000025646 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000160928 ENTREZGENE
MGD MGI:6721469 ENTREZGENE
NCBI Gene Atrip-trex1 ENTREZGENE
PhenoGen Gm53191 PhenoGen
RNAcentral URS0000CCE152 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-08-03 Gm53191  predicted gene, 53191  Atrip-trex1  Atrip-Trex1 readthrough  Symbol and/or name change 5135510 APPROVED
2020-06-19 Atrip-trex1  Atrip-Trex1 readthrough  Atrip  ATR interacting protein  Symbol and/or name change 5135510 APPROVED