Chadl (chondroadherin-like) - Rat Genome Database

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Gene: Chadl (chondroadherin-like) Mus musculus
Analyze
Symbol: Chadl
Name: chondroadherin-like
RGD ID: 1322575
MGI Page MGI
Description: Predicted to enable collagen binding activity and collagen fibril binding activity. Involved in negative regulation of chondrocyte differentiation. Located in collagen-containing extracellular matrix. Is expressed in ureteric tip. Orthologous to human CHADL (chondroadherin like).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AY100452; chondroadherin pseudogene; chondroadherin-like protein; D930017K21Rik; leucine rich repeat containing 15 pseudogene
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Note: We previously annotated two pseudogenes overlapping this gene, based on predictions from pseudogene.org. Our curation indicates that this locus is protein-coding. [28 Nov 2011]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,570,366 - 81,581,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,562,497 - 81,581,488 (-)EnsemblGRCm39 Ensembl
GRCm381581,686,166 - 81,697,373 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,678,296 - 81,697,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371581,516,596 - 81,527,717 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,519,375 - 81,524,491 (-)NCBIMGSCv36mm8
Celera1583,805,272 - 83,816,393 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12040188   PMID:12364608   PMID:12466851   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21873635   PMID:25451920   PMID:28705898  


Genomics

Comparative Map Data
Chadl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391581,570,366 - 81,581,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1581,562,497 - 81,581,488 (-)EnsemblGRCm39 Ensembl
GRCm381581,686,166 - 81,697,373 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1581,678,296 - 81,697,287 (-)EnsemblGRCm38mm10GRCm38
MGSCv371581,516,596 - 81,527,717 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361581,519,375 - 81,524,491 (-)NCBIMGSCv36mm8
Celera1583,805,272 - 83,816,393 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1538.2NCBI
CHADL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,229,513 - 41,240,931 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,229,510 - 41,240,931 (-)EnsemblGRCh38hg38GRCh38
GRCh372241,625,517 - 41,636,935 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,625,514 - 41,636,935 (-)NCBINCBI36Build 36hg18NCBI36
Celera2225,431,894 - 25,443,315 (-)NCBICelera
Cytogenetic Map22q13.2NCBI
HuRef2224,589,978 - 24,601,405 (-)NCBIHuRef
CHM1_12241,585,206 - 41,596,627 (-)NCBICHM1_1
T2T-CHM13v2.02241,702,131 - 41,715,871 (-)NCBIT2T-CHM13v2.0
Chadl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87115,085,447 - 115,097,565 (-)NCBIGRCr8
mRatBN7.27113,205,323 - 113,218,678 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7113,210,748 - 113,217,272 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.07122,915,847 - 122,929,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,922,022 - 122,926,336 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,890,343 - 122,903,626 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7109,524,311 - 109,537,591 (-)NCBICelera
Cytogenetic Map7q34NCBI
Chadl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541326,851,420 - 26,862,081 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541326,846,714 - 26,862,082 (-)NCBIChiLan1.0ChiLan1.0
CHADL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22351,041,313 - 51,073,980 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12253,742,551 - 53,773,900 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02222,106,953 - 22,138,122 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12240,197,763 - 40,205,636 (-)NCBIpanpan1.1PanPan1.1panPan2
CHADL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11023,992,848 - 24,006,492 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1023,953,912 - 24,003,162 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1023,925,004 - 23,942,058 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01024,737,290 - 24,754,362 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1024,698,297 - 24,747,502 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11024,453,725 - 24,470,781 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01024,774,588 - 24,791,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01024,949,120 - 24,966,177 (+)NCBIUU_Cfam_GSD_1.0
Chadl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049457,623,231 - 7,633,134 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936492633,477 - 646,002 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936492633,443 - 643,550 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHADL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl57,248,444 - 7,253,170 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.157,246,892 - 7,258,962 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.254,528,187 - 4,540,245 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHADL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11923,772,516 - 23,785,210 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1923,778,433 - 23,783,250 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045101,638,789 - 101,651,599 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chadl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247527,283,639 - 7,289,531 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247527,284,344 - 7,293,815 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Chadl
331 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2010
Count of miRNA genes:717
Interacting mature miRNAs:927
Transcripts:ENSMUST00000072910, ENSMUST00000173598, ENSMUST00000173898
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1301429Pcir3_mperiosteal circumference 3 (mouse)Not determined154846536282465496Mouse
4142198Hbtq_mhabituation QTL (mouse)Not determined155116070885160833Mouse
10045637Heal27_mwound healing/regeneration 29 (mouse)Not determined155141836185418511Mouse
10412067Pain2_mpain 2 (mouse)Not determined155164533985645626Mouse
1302080Szs13_mseizure susceptibility 13 (mouse)Not determined155168583285694449Mouse
1301708Cocrb14_mcocaine related behavior 14 (mouse)Not determined155180651585806651Mouse
38501067Tip3_mtuberculosis immunophenotype 3, IFN-g level (mouse)155356339689584203Mouse
13504731Cath5_mcarotid atherosclerosis 5 (mouse)155478912988789129Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
27095936Ulnl4_mulna length 4, 5 week (mouse)155676339687684201Mouse
1300800Ses3_msalmonella enteritidis susceptibility 3 (mouse)Not determined155711700591117153Mouse
1357407Pfat4_mpredicted fat percentage 4 (mouse)8.6Body fat amountpredicted fat percentage155711700591117153Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
15092079Igly6_mIgG glycosylation 6, GP6 (mouse)157410054082674156Mouse
1301472Pain1_mpain 1 (mouse)Not determined157532084690813185Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
15092080Igly7_mIgG glycosylation 7, GP10 (mouse)157779491982674156Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
25394540Skmw82_mskeletal muscle weight 82, soleus (mouse)158143443681671139Mouse

Markers in Region
UniSTS:237358  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381581,687,484 - 81,687,570UniSTSGRCm38
MGSCv371581,517,914 - 81,518,000UniSTSGRCm37
Celera1583,806,590 - 83,806,676UniSTS
Cytogenetic Map15E1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000072910   ⟹   ENSMUSP00000072682
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,570,366 - 81,581,488 (-)Ensembl
GRCm38.p6 Ensembl1581,686,165 - 81,697,287 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173598   ⟹   ENSMUSP00000133834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,562,497 - 81,578,229 (-)Ensembl
GRCm38.p6 Ensembl1581,678,296 - 81,694,028 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173898   ⟹   ENSMUSP00000133981
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,570,382 - 81,578,408 (-)Ensembl
GRCm38.p6 Ensembl1581,686,181 - 81,694,207 (-)Ensembl
RefSeq Acc Id: ENSMUST00000230849
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1581,578,325 - 81,579,736 (-)Ensembl
GRCm38.p6 Ensembl1581,694,124 - 81,695,535 (-)Ensembl
RefSeq Acc Id: NM_001164320   ⟹   NP_001157792
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,570,367 - 81,581,488 (-)NCBI
GRCm381581,686,166 - 81,697,287 (-)NCBI
MGSCv371581,516,596 - 81,527,717 (-)RGD
Celera1583,805,272 - 83,816,393 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006520742   ⟹   XP_006520805
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,570,378 - 81,581,372 (-)NCBI
GRCm381581,686,177 - 81,696,673 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030248458   ⟹   XP_030104318
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,575,069 - 81,581,564 (-)NCBI
GRCm381581,690,868 - 81,697,373 (-)NCBI
Sequence:
RefSeq Acc Id: XR_383996
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391581,570,366 - 81,581,564 (-)NCBI
GRCm381581,686,177 - 81,697,373 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001157792   ⟸   NM_001164320
- Peptide Label: precursor
- UniProtKB: E9Q7T7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006520805   ⟸   XM_006520742
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_030104318   ⟸   XM_030248458
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000072682   ⟸   ENSMUST00000072910
RefSeq Acc Id: ENSMUSP00000133834   ⟸   ENSMUST00000173598
RefSeq Acc Id: ENSMUSP00000133981   ⟸   ENSMUST00000173898
Protein Domains
LRRCT   LRRNT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9Q7T7-F1-model_v2 AlphaFold E9Q7T7 1-748 view protein structure

Promoters
RGD ID:6825660
Promoter ID:MM_KWN:19162
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   MEF_B4
Transcripts:AK086273_CHADL,   ENSMUST00000109562,   UC007WWW.1,   UC007WWX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,524,601 - 81,525,512 (-)MPROMDB
RGD ID:6825859
Promoter ID:MM_KWN:19163
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000072910,   NM_001164320
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361581,527,251 - 81,527,751 (-)MPROMDB
RGD ID:8684448
Promoter ID:EPDNEW_M20254
Type:multiple initiation site
Name:Chadl_1
Description:Mus musculus chondroadherin-like , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381581,697,284 - 81,697,344EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3036284 AgrOrtholog
Ensembl Genes ENSMUSG00000063765 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000072910 ENTREZGENE
  ENSMUST00000072910.6 UniProtKB/Swiss-Prot
  ENSMUST00000173598.8 UniProtKB/TrEMBL
  ENSMUST00000173898.2 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:214685 UniProtKB/Swiss-Prot
MGD MGI:3036284 ENTREZGENE
NCBI Gene 214685 ENTREZGENE
PANTHER CHONDROADHERIN-LIKE PROTEIN UniProtKB/Swiss-Prot
  CHONDROADHERIN-LIKE PROTEIN-RELATED UniProtKB/TrEMBL
  KEKKON 5, ISOFORM A UniProtKB/TrEMBL
  LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/TrEMBL
Pfam LRR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRCT UniProtKB/Swiss-Prot
PhenoGen Chadl PhenoGen
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_BAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRRNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CHADL_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  G3UXV0_MOUSE UniProtKB/TrEMBL
  G3UY83_MOUSE UniProtKB/TrEMBL
  Q8K3I0_MOUSE UniProtKB/TrEMBL