Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1) - Rat Genome Database

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Gene: Plekhg1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1) Mus musculus
Analyze
Symbol: Plekhg1
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
RGD ID: 1321124
MGI Page MGI
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be located in nucleoplasm. Is expressed in several structures, including brain and retina. Orthologous to human PLEKHG1 (pleckstrin homology and RhoGEF domain containing G1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D10Ertd733; D10Ertd733e; Gm521; mKIAA1209; pleckstrin homology domain-containing family G member 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm7126  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39103,690,206 - 3,917,303 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl103,690,364 - 3,917,303 (+)EnsemblGRCm39 Ensembl
GRCm38103,740,251 - 3,967,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl103,740,364 - 3,967,303 (+)EnsemblGRCm38mm10GRCm38
MGSCv37106,379,238 - 6,606,164 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36106,381,992 - 6,473,874 (-)NCBIMGSCv36mm8
Celera103,669,512 - 3,895,132 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
4. Mouse MP Annotation Import Pipeline RGD automated import pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:17967808   PMID:18799693  
PMID:21565611   PMID:21677750   PMID:21873635   PMID:22008794   PMID:23341629   PMID:24952961   PMID:30578296   PMID:30926747   PMID:30973865   PMID:33431871   PMID:38355793   PMID:38912572  


Genomics

Comparative Map Data
Plekhg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39103,690,206 - 3,917,303 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl103,690,364 - 3,917,303 (+)EnsemblGRCm39 Ensembl
GRCm38103,740,251 - 3,967,303 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl103,740,364 - 3,967,303 (+)EnsemblGRCm38mm10GRCm38
MGSCv37106,379,238 - 6,606,164 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36106,381,992 - 6,473,874 (-)NCBIMGSCv36mm8
Celera103,669,512 - 3,895,132 (+)NCBICelera
Cytogenetic Map10A1NCBI
cM Map102.06NCBI
PLEKHG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386150,599,885 - 150,843,665 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6150,599,883 - 150,843,665 (+)EnsemblGRCh38hg38GRCh38
GRCh376150,921,021 - 151,164,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,962,692 - 151,206,492 (+)NCBINCBI36Build 36hg18NCBI36
Build 346151,217,894 - 151,256,913NCBI
Celera6151,655,965 - 151,898,659 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6148,515,324 - 148,728,369 (+)NCBIHuRef
CHM1_16151,184,815 - 151,428,538 (+)NCBICHM1_1
T2T-CHM13v2.06151,800,395 - 152,044,215 (+)NCBIT2T-CHM13v2.0
Plekhg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,612,023 - 42,841,727 (+)NCBIGRCr8
mRatBN7.2140,348,684 - 40,434,063 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl140,311,221 - 40,434,063 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx140,875,690 - 40,961,087 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,862,884 - 46,948,285 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0140,951,325 - 41,036,723 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0140,286,908 - 40,521,395 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl140,389,638 - 40,520,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0141,637,081 - 41,868,666 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4134,591,855 - 34,677,812 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera136,040,218 - 36,125,350 (+)NCBICelera
Cytogenetic Map1p11NCBI
Plekhg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543910,636,381 - 10,746,745 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543910,636,444 - 10,755,814 (-)NCBIChiLan1.0ChiLan1.0
PLEKHG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25170,618,043 - 170,864,097 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16168,511,574 - 168,755,296 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06148,411,676 - 148,657,616 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16153,169,535 - 153,362,070 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6153,240,586 - 153,362,070 (+)Ensemblpanpan1.1panPan2
PLEKHG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1141,073,748 - 41,297,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl141,072,500 - 41,295,138 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha141,914,652 - 42,138,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0141,258,670 - 41,482,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl141,313,940 - 41,479,995 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1141,133,917 - 41,357,417 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0140,977,666 - 41,201,291 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0141,481,825 - 41,705,985 (+)NCBIUU_Cfam_GSD_1.0
Plekhg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946136,508,740 - 136,589,487 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364893,760,831 - 3,838,926 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364893,635,960 - 3,840,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl115,341,638 - 15,587,590 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1115,341,634 - 15,588,224 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLEKHG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11378,034,968 - 78,285,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1378,154,150 - 78,287,996 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604050,337,476 - 50,580,807 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247857,338,592 - 7,513,435 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247857,340,310 - 7,590,385 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekhg1
7718 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2663
Count of miRNA genes:687
Interacting mature miRNAs:868
Transcripts:ENSMUST00000042438, ENSMUST00000120274, ENSMUST00000131525, ENSMUST00000136671, ENSMUST00000137111, ENSMUST00000141367, ENSMUST00000144543, ENSMUST00000154727
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11532718Sluc44f_msusceptibility to lung cancer 44f (mouse)10126289265Mouse
1357813Ath20_matherosclerosis 20 (mouse)Not determined10328318537283334Mouse
11532717Sluc44g_msusceptibility to lung cancer 44g (mouse)10126289265Mouse
1300881Sluc29_msusceptibility to lung cancer 29 (mouse)Not determined10126289265Mouse
12879494Facq1_mfear acquisition QTL 1 (mouse)10131279130Mouse
1300759Geot_mgeotaxia (mouse)Not determined10126289265Mouse
1300790Pgia6_mproteoglycan induced arthritis 6 (mouse)Not determined10381017137810295Mouse
15039341Nmrs28_mNAFLD-associated magnetic resonance shift 28 (mouse)1035100134351001Mouse
11533917Mts2_mmammary tumor susceptibility 2 (mouse)10126289265Mouse
11532725Sluc44b_msusceptibility to lung cancer 44b (mouse)10126289265Mouse
11532724Sluc44c_msusceptibility to lung cancer 44c (mouse)10126289265Mouse
11532723Sluc44d_msusceptibility to lung cancer 44d (mouse)10126289265Mouse
11532722Sluc44e_msusceptibility to lung cancer 44e (mouse)10126289265Mouse
11532721Sluc44_msusceptibility to lung cancer 44 (mouse)10126289265Mouse
11532720Sluc44a_msusceptibility to lung cancer 44a (mouse)10126289265Mouse

Markers in Region
D10Mit166  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,887,960 - 3,888,068UniSTSGRCm38
MGSCv37106,458,473 - 6,458,581UniSTSGRCm37
Celera103,815,210 - 3,815,296UniSTS
Cytogenetic Map10A1UniSTS
cM Map104.0UniSTS
Whitehead Genetic102.2UniSTS
UniSTS:236300  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,958,100 - 3,958,361UniSTSGRCm38
MGSCv37106,388,180 - 6,388,441UniSTSGRCm37
Celera103,885,876 - 3,886,137UniSTS
Cytogenetic Map10A1UniSTS
UniSTS:236301  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,825,780 - 3,826,043UniSTSGRCm38
MGSCv37106,520,498 - 6,520,761UniSTSGRCm37
Celera103,753,106 - 3,753,369UniSTS
Cytogenetic Map10A1UniSTS
D10Ertd733e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38103,958,962 - 3,959,164UniSTSGRCm38
MGSCv37106,387,377 - 6,387,579UniSTSGRCm37
Celera103,886,738 - 3,886,940UniSTS
Cytogenetic Map10A1UniSTS
cM Map101.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001033253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001159942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006512443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011243078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC153570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC155943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK135923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC076628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000042438   ⟹   ENSMUSP00000040495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,822,667 - 3,917,303 (+)Ensembl
GRCm38.p6 Ensembl103,872,667 - 3,967,303 (+)Ensembl
Ensembl Acc Id: ENSMUST00000120274   ⟹   ENSMUSP00000114056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,690,364 - 3,917,303 (+)Ensembl
GRCm38.p6 Ensembl103,740,364 - 3,967,303 (+)Ensembl
Ensembl Acc Id: ENSMUST00000131525
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,853,582 - 3,869,362 (+)Ensembl
GRCm38.p6 Ensembl103,903,582 - 3,919,362 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136671   ⟹   ENSMUSP00000119950
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,822,667 - 3,914,549 (+)Ensembl
GRCm38.p6 Ensembl103,872,667 - 3,964,549 (+)Ensembl
Ensembl Acc Id: ENSMUST00000137111
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,690,665 - 3,888,577 (+)Ensembl
GRCm38.p6 Ensembl103,740,665 - 3,938,577 (+)Ensembl
Ensembl Acc Id: ENSMUST00000141367   ⟹   ENSMUSP00000116652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,907,891 - 3,913,526 (+)Ensembl
GRCm38.p6 Ensembl103,957,891 - 3,963,526 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144543
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,690,378 - 3,888,595 (+)Ensembl
GRCm38.p6 Ensembl103,740,378 - 3,938,595 (+)Ensembl
Ensembl Acc Id: ENSMUST00000154727   ⟹   ENSMUSP00000122131
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,853,586 - 3,917,298 (+)Ensembl
GRCm38.p6 Ensembl103,903,586 - 3,967,298 (+)Ensembl
Ensembl Acc Id: ENSMUST00000238840
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,784,964 - 3,869,422 (+)Ensembl
GRCm38.p6 Ensembl103,834,964 - 3,919,422 (+)Ensembl
Ensembl Acc Id: ENSMUST00000239159   ⟹   ENSMUSP00000159056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl103,784,879 - 3,914,452 (+)Ensembl
GRCm38.p6 Ensembl103,834,879 - 3,964,452 (+)Ensembl
RefSeq Acc Id: NM_001033253   ⟹   NP_001028425
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,822,667 - 3,917,303 (+)NCBI
GRCm38103,872,667 - 3,967,303 (+)NCBI
MGSCv37106,379,238 - 6,606,164 (-)RGD
Celera103,669,512 - 3,895,132 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001159942   ⟹   NP_001153414
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,690,377 - 3,917,303 (+)NCBI
GRCm38103,740,377 - 3,967,303 (+)NCBI
MGSCv37106,379,238 - 6,606,164 (-)RGD
Celera103,669,512 - 3,895,132 (+)RGD
cM Map10 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512439   ⟹   XP_006512502
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,775,129 - 3,917,303 (+)NCBI
GRCm38103,825,144 - 3,967,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512442   ⟹   XP_006512505
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,809,559 - 3,917,303 (+)NCBI
GRCm38103,859,557 - 3,967,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512443   ⟹   XP_006512506
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,813,648 - 3,917,303 (+)NCBI
GRCm38103,863,524 - 3,967,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243077   ⟹   XP_011241379
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,690,599 - 3,917,303 (+)NCBI
GRCm38103,740,621 - 3,967,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011243078   ⟹   XP_011241380
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,690,206 - 3,917,303 (+)NCBI
GRCm38103,740,251 - 3,967,303 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004936151
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39103,775,129 - 3,913,526 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001028425   ⟸   NM_001033253
- UniProtKB: Q3UX37 (UniProtKB/TrEMBL),   F6S200 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001153414   ⟸   NM_001159942
- UniProtKB: Q3UX37 (UniProtKB/TrEMBL),   F6S200 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512502   ⟸   XM_006512439
- Peptide Label: isoform X1
- UniProtKB: A0A5F8MPP0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512505   ⟸   XM_006512442
- Peptide Label: isoform X2
- UniProtKB: F6S200 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006512506   ⟸   XM_006512443
- Peptide Label: isoform X3
- UniProtKB: Q3UX37 (UniProtKB/TrEMBL),   F6S200 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241380   ⟸   XM_011243078
- Peptide Label: isoform X3
- UniProtKB: Q3UX37 (UniProtKB/TrEMBL),   F6S200 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011241379   ⟸   XM_011243077
- Peptide Label: isoform X3
- UniProtKB: Q3UX37 (UniProtKB/TrEMBL),   F6S200 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000159056   ⟸   ENSMUST00000239159
Ensembl Acc Id: ENSMUSP00000040495   ⟸   ENSMUST00000042438
Ensembl Acc Id: ENSMUSP00000122131   ⟸   ENSMUST00000154727
Ensembl Acc Id: ENSMUSP00000114056   ⟸   ENSMUST00000120274
Ensembl Acc Id: ENSMUSP00000119950   ⟸   ENSMUST00000136671
Ensembl Acc Id: ENSMUSP00000116652   ⟸   ENSMUST00000141367
Protein Domains
DH   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A5F8MPP0-F1-model_v2 AlphaFold A0A5F8MPP0 1-1465 view protein structure

Promoters
RGD ID:8671390
Promoter ID:EPDNEW_M13726
Type:initiation region
Name:Plekhg1_1
Description:Mus musculus pleckstrin homology domain containing, family Gmember 1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13727  EPDNEW_M13728  EPDNEW_M13729  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38103,740,378 - 3,740,438EPDNEW
RGD ID:8671392
Promoter ID:EPDNEW_M13727
Type:single initiation site
Name:Plekhg1_2
Description:Mus musculus pleckstrin homology domain containing, family Gmember 1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13726  EPDNEW_M13728  EPDNEW_M13729  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38103,740,665 - 3,740,725EPDNEW
RGD ID:8671394
Promoter ID:EPDNEW_M13728
Type:single initiation site
Name:Plekhg1_4
Description:Mus musculus pleckstrin homology domain containing, family Gmember 1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13726  EPDNEW_M13727  EPDNEW_M13729  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38103,758,399 - 3,758,459EPDNEW
RGD ID:8671396
Promoter ID:EPDNEW_M13729
Type:single initiation site
Name:Plekhg1_3
Description:Mus musculus pleckstrin homology domain containing, family Gmember 1 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M13726  EPDNEW_M13727  EPDNEW_M13728  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38103,872,640 - 3,872,700EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676551 AgrOrtholog
Ensembl Genes ENSMUSG00000040624 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000042438 ENTREZGENE
  ENSMUST00000042438.13 UniProtKB/TrEMBL
  ENSMUST00000120274 ENTREZGENE
  ENSMUST00000120274.8 UniProtKB/TrEMBL
  ENSMUST00000136671.8 UniProtKB/TrEMBL
  ENSMUST00000141367.2 UniProtKB/TrEMBL
  ENSMUST00000154727.2 UniProtKB/TrEMBL
  ENSMUST00000239159 ENTREZGENE
  ENSMUST00000239159.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  PH_PLEKHG1_G2_G3 UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
KEGG Report mmu:213783 UniProtKB/TrEMBL
MGD MGI:2676551 ENTREZGENE
NCBI Gene 213783 ENTREZGENE
PANTHER FI17866P1 UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 1 UniProtKB/TrEMBL
Pfam RhoGEF UniProtKB/TrEMBL
  SOS1_NGEF_PH UniProtKB/TrEMBL
PhenoGen Plekhg1 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A5F8MPP0 ENTREZGENE, UniProtKB/TrEMBL
  F6S200 ENTREZGENE, UniProtKB/TrEMBL
  F7C583_MOUSE UniProtKB/TrEMBL
  F7CES2_MOUSE UniProtKB/TrEMBL
  Q148U4_MOUSE UniProtKB/TrEMBL
  Q148U5_MOUSE UniProtKB/TrEMBL
  Q3UX37 ENTREZGENE, UniProtKB/TrEMBL
  Q3V381_MOUSE UniProtKB/TrEMBL
  Q3V3C5_MOUSE UniProtKB/TrEMBL
  Q3V3S7_MOUSE UniProtKB/TrEMBL
  Q6DFV4_MOUSE UniProtKB/TrEMBL
  Q80TH7_MOUSE UniProtKB/TrEMBL