Gga3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3) - Rat Genome Database

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Gene: Gga3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3) Mus musculus
Analyze
Symbol: Gga3
Name: golgi associated, gamma adaptin ear containing, ARF binding protein 3
RGD ID: 1319956
MGI Page MGI
Description: Predicted to enable protein transporter activity; small GTPase binding activity; and ubiquitin binding activity. Acts upstream of or within positive regulation of protein catabolic process and protein localization to lysosome. Predicted to be located in Golgi apparatus; endosome; and lysosome. Predicted to be part of protein-containing complex. Predicted to be active in trans-Golgi network. Is expressed in several structures, including heart; liver; lung; metanephros; and white fat. Orthologous to human GGA3 (golgi associated, gamma adaptin ear containing, ARF binding protein 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ADP-ribosylation factor-binding protein GGA3; C230037M19Rik; golgi-localized, gamma ear-containing, ARF-binding protein 3; mKIAA0154
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,475,081 - 115,495,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,475,081 - 115,494,877 (-)EnsemblGRCm39 Ensembl
GRCm3811115,584,255 - 115,604,517 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,584,255 - 115,604,051 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,445,569 - 115,465,220 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,400,801 - 115,419,975 (-)NCBIMGSCv36mm8
Celera11127,352,022 - 127,371,680 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.89NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gga3Mousecombined oxidative phosphorylation deficiency 34  ISOGGA3 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:28492532
Gga3Mousenephrotic syndrome type 17  ISOGGA3 (Homo sapiens)8554872ClinVar Annotator: match by term: Nephrotic syndrome and type 17ClinVarPMID:25741868 and PMID:30179222

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gga3Mouse1,2-dimethylhydrazine multiple interactionsEXP 6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of GGA3 mRNACTDPMID:22206623
Gga3Mouse17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of GGA3 mRNACTDPMID:17555576
Gga3Mouse17alpha-ethynylestradiol multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GGA3 mRNACTDPMID:17942748
Gga3Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GGA3 mRNACTDPMID:17942748
Gga3Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOGga3 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of GGA3 mRNACTDPMID:33387578
Gga3Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of GGA3 mRNACTDPMID:21570461 and PMID:24680724
Gga3Mouse2,4-dinitrotoluene affects expressionISOGga3 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of GGA3 mRNACTDPMID:21346803
Gga3Mouse2-methylcholine affects expressionISOGGA3 (Homo sapiens)6480464beta-methylcholine affects the expression of GGA3 mRNACTDPMID:21179406
Gga3Mouse3,4-methylenedioxymethamphetamine decreases expressionEXP 6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of GGA3 mRNACTDPMID:26251327
Gga3Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of GGA3 mRNACTDPMID:39298647
Gga3Mouse6-propyl-2-thiouracil decreases expressionISOGga3 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of GGA3 mRNACTDPMID:30047161
Gga3Mouseacrolein multiple interactionsISOGGA3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of GGA3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of GGA3 mRNACTDPMID:32699268
Gga3Mouseaflatoxin B1 increases expressionEXP 6480464Aflatoxin B1 results in increased expression of GGA3 mRNACTDPMID:19770486
Gga3Mousealpha-pinene multiple interactionsISOGGA3 (Homo sapiens)6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of GGA3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of GGA3 mRNACTDPMID:32699268
Gga3Mousearsenous acid multiple interactionsISOGGA3 (Homo sapiens)6480464Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to GGA3 protein]CTDPMID:26598702
Gga3Mousebenzo[a]pyrene decreases methylationISOGGA3 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of GGA3 3' UTRCTDPMID:27901495
Gga3Mousebisphenol A increases expressionISOGga3 (Rattus norvegicus)6480464bisphenol A results in increased expression of GGA3 mRNACTDPMID:25181051 and PMID:34947998
Gga3Mousebisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of GGA3 mRNACTDPMID:32156529 and PMID:38074096
Gga3Mousebisphenol A decreases methylationEXP 6480464bisphenol A results in decreased methylation of GGA3 promoterCTDPMID:27312807
Gga3Mousebisphenol F decreases expressionEXP 6480464bisphenol F results in decreased expression of GGA3 mRNACTDPMID:38685157

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gga3Mouseendocytic recycling involved_inIEAUniProtKB:A0A0G2JV04 and ensembl:ENSRNOP000000902432290270 EnsemblGO_REF:0000107
Gga3Mouseendocytic recycling involved_inISOGga3 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Gga3MouseGolgi to plasma membrane protein transport involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3MouseGolgi to plasma membrane protein transport involved_inISSUniProtKB:Q9NZ522290270 UniProtGO_REF:0000024
Gga3MouseGolgi to plasma membrane transport involved_inIBAPANTHER:PTN001015167 more ...2290270 GO_CentralGO_REF:0000033
Gga3Mousenegative regulation of amyloid-beta formation involved_inISSUniProtKB:Q9NZ522290270 UniProtGO_REF:0000024
Gga3Mousenegative regulation of amyloid-beta formation involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mousepositive regulation of protein catabolic process acts_upstream_of_or_withinIGIMGI:21462072290270 PMID:22836275MGIPMID:22836275
Gga3Mouseprotein catabolic process acts_upstream_ofIGIMGI:21462072290270 PMID:22836275MGIPMID:22836275
Gga3Mouseprotein destabilization involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseprotein destabilization involved_inISSUniProtKB:Q9NZ522290270 UniProtGO_REF:0000024
Gga3Mouseprotein localization to cell surface involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseprotein localization to cell surface involved_inIBAPANTHER:PTN001015167 more ...2290270 GO_CentralGO_REF:0000033
Gga3Mouseprotein localization to cell surface involved_inISSUniProtKB:Q9NZ522290270 UniProtGO_REF:0000024
Gga3Mouseprotein localization to lysosome acts_upstream_of_or_withinIMP 2290270 PMID:25592972MGIPMID:25592972
Gga3Mouseprotein targeting to lysosome involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseprotein targeting to lysosome involved_inIEAUniProtKB:Q9NZ52 and ensembl:ENSP000004380852290270 EnsemblGO_REF:0000107
Gga3Mouseregulation of protein stability involved_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseregulation of protein stability involved_inISSUniProtKB:Q9NZ522290270 UniProtGO_REF:0000024
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Cellular Component
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Object Symbol
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Evidence
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Reference
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Original Reference(s)
Gga3Mouseearly endosome located_inISOGga3 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Gga3Mouseearly endosome membrane located_inIEAUniProtKB-SubCell:SL-00932290270 UniProtGO_REF:0000044
Gga3MouseGolgi apparatus located_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouselysosome located_inISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouselysosome located_inIEAUniProtKB:Q9NZ52 and ensembl:ENSP000004380852290270 EnsemblGO_REF:0000107
Gga3Mouseprotein-containing complex part_ofISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseprotein-containing complex part_ofIEAUniProtKB:Q9NZ52 and ensembl:ENSP000004380852290270 EnsemblGO_REF:0000107
Gga3Mouserecycling endosome located_inISOGga3 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Gga3Mouserecycling endosome membrane located_inIEAUniProtKB-SubCell:SL-02312290270 UniProtGO_REF:0000044
Gga3Mousetrans-Golgi network located_inISOUniProtKB:Q9NZ522290270 MGIGO_REF:0000008 and GO_REF:0000119
Gga3Mousetrans-Golgi network is_active_inIBAPANTHER:PTN001015167 more ...2290270 GO_CentralGO_REF:0000033
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Molecular Function
1 to 20 of 23 rows

  
Object Symbol
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Evidence
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Reference
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Source
Original Reference(s)
Gga3Mousephosphatidylinositol binding enablesIEAInterPro:IPR002014 and InterPro:IPR0041522290270 InterProGO_REF:0000002
Gga3Mouseprotein binding enablesISOUniProtKB:P046299068941 PMID:26446845UniProtPMID:26446845
Gga3Mouseprotein binding enablesISOUniProtKB:Q132589068941 PMID:32334026IntActPMID:32334026
Gga3Mouseprotein binding enablesISOUniProtKB:P0CG479068941 PMID:15039775IntActPMID:15039775
Gga3Mouseprotein binding enablesISOUniProtKB:P11717 more ...9068941 PMID:37100772IntActPMID:37100772
Gga3Mouseprotein binding enablesISOUniProtKB:P11717 and UniProtKB:Q6VY079068941 PMID:16977309IntActPMID:16977309
Gga3Mouseprotein binding enablesISOUniProtKB:Q9UJY4 and UniProtKB:Q9UJY59068941 PMID:14638859IntActPMID:14638859
Gga3Mouseprotein binding enablesISOUniProtKB:O75865-2 more ...9068941 PMID:32296183IntActPMID:32296183
Gga3Mouseprotein binding enablesISOUniProtKB:P11717 and UniProtKB:P206459068941 PMID:11387475IntActPMID:11387475
Gga3Mouseprotein binding enablesISOUniProtKB:P568179068941 PMID:26053850IntActPMID:26053850
Gga3Mouseprotein binding enablesISOUniProtKB:P623309068941 PMID:23143332 and PMID:24056087IntActPMID:23143332 and PMID:24056087
Gga3Mouseprotein binding enablesISOUniProtKB:Q152769068941 PMID:12505986IntActPMID:12505986
Gga3Mouseprotein binding enablesISOUniProtKB:P357399068941PMID:26446845UniProtPMID:26446845 and REF_RGD_ID:11554955
Gga3Mouseprotein binding enablesISOUniProtKB:P180899068941 PMID:26811329UniProtPMID:26811329
Gga3Mouseprotein binding enablesISOUniProtKB:Q135719068941 PMID:17116753ARUK-UCLPMID:17116753
Gga3Mouseprotein transporter activity enablesIEAUniProtKB:Q9NZ52 and ensembl:ENSP000004380852290270 EnsemblGO_REF:0000107
Gga3Mouseprotein transporter activity enablesISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mouseprotein-containing complex binding enablesIEAUniProtKB:Q9NZ52 and ensembl:ENSP000004380852290270 EnsemblGO_REF:0000107
Gga3Mouseprotein-containing complex binding enablesISOUniProtKB:Q9NZ522290270 GO_CentralGO_REF:0000119
Gga3Mousesmall GTPase binding enablesIBAPANTHER:PTN001015167 more ...2290270 GO_CentralGO_REF:0000033
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Imported Annotations - PID (archival)

Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Gga3MouseArf family mediated signaling pathway  ISOGGA3 (Homo sapiens)6484113 PIDPID:200195

#
Reference Title
Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:14621295   PMID:15741177   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693   PMID:20484053   PMID:21267068   PMID:21873635   PMID:22291915   PMID:22836275   PMID:24089482   PMID:25592972   PMID:27192432  
PMID:28190767   PMID:29391027   PMID:32325033   PMID:33208500  



Gga3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,475,081 - 115,495,501 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,475,081 - 115,494,877 (-)EnsemblGRCm39 Ensembl
GRCm3811115,584,255 - 115,604,517 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,584,255 - 115,604,051 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,445,569 - 115,465,220 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,400,801 - 115,419,975 (-)NCBIMGSCv36mm8
Celera11127,352,022 - 127,371,680 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.89NCBI
GGA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381775,236,599 - 75,262,363 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1775,236,599 - 75,262,363 (-)EnsemblGRCh38hg38GRCh38
GRCh371773,232,694 - 73,258,444 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,744,290 - 70,769,272 (-)NCBINCBI36Build 36hg18NCBI36
Build 341770,744,289 - 70,769,272NCBI
Celera1769,825,023 - 69,850,791 (-)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1768,642,387 - 68,668,634 (-)NCBIHuRef
CHM1_11773,297,254 - 73,323,022 (-)NCBICHM1_1
T2T-CHM13v2.01776,128,675 - 76,154,454 (-)NCBIT2T-CHM13v2.0
Gga3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,324,378 - 101,342,373 (-)NCBIGRCr8
mRatBN7.210100,825,427 - 100,843,422 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10100,825,426 - 100,844,462 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10105,885,638 - 105,904,664 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,348,711 - 105,367,737 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010100,746,398 - 100,765,434 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010104,137,655 - 104,156,576 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10104,137,655 - 104,156,576 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,124,628 - 104,143,981 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,665,476 - 105,684,513 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110105,680,483 - 105,698,186 (-)NCBI
Celera1099,399,869 - 99,418,903 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Gga3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555532,108,379 - 2,124,748 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555532,103,694 - 2,124,748 (-)NCBIChiLan1.0ChiLan1.0
GGA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21991,275,986 - 91,301,164 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11796,099,060 - 96,124,342 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01769,185,045 - 69,208,766 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11774,737,164 - 74,762,039 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1774,737,164 - 74,762,039 (-)Ensemblpanpan1.1panPan2
GGA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,235,377 - 5,250,982 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl95,235,025 - 5,249,361 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha95,913,638 - 5,929,958 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.095,904,719 - 5,921,031 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl95,905,524 - 5,921,037 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.195,943,474 - 5,959,763 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.096,053,691 - 6,070,007 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.096,113,427 - 6,130,011 (+)NCBIUU_Cfam_GSD_1.0
Gga3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056025,863,468 - 5,886,500 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594532,342 - 548,440 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594531,844 - 548,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GGA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl126,055,696 - 6,074,478 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1126,051,854 - 6,072,424 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,023,618 - 6,034,858 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GGA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,410,941 - 46,432,560 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,411,391 - 46,432,991 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607717,181,468 - 17,202,614 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gga3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248015,059,126 - 5,073,157 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248015,057,611 - 5,073,276 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gga3
643 total Variants

Predicted Target Of
Summary Value
Count of predictions:3029
Count of miRNA genes:723
Interacting mature miRNAs:910
Transcripts:ENSMUST00000019135, ENSMUST00000106508, ENSMUST00000123485, ENSMUST00000123831, ENSMUST00000125097, ENSMUST00000128437, ENSMUST00000132503, ENSMUST00000136790, ENSMUST00000148782, ENSMUST00000149814, ENSMUST00000154832, ENSMUST00000156173
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 28 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1301012Vispl_mvisual placing (mouse)Not determined11101022590121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse

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UniSTS:236776  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811115,584,567 - 115,584,689UniSTSGRCm38
MGSCv3711115,445,881 - 115,446,003UniSTSGRCm37
Celera11127,352,334 - 127,352,456UniSTS
Cytogenetic Map11E2UniSTS






1 to 28 of 28 rows
RefSeq Transcripts NM_001252067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006533365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011249032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004936965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_388465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK031086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW551893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC025051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC110676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY268727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY296723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 28 of 28 rows

Ensembl Acc Id: ENSMUST00000019135   ⟹   ENSMUSP00000019135
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,475,081 - 115,494,877 (-)Ensembl
GRCm38.p6 Ensembl11115,584,255 - 115,604,051 (-)Ensembl
Ensembl Acc Id: ENSMUST00000106508   ⟹   ENSMUSP00000102117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,475,081 - 115,494,877 (-)Ensembl
GRCm38.p6 Ensembl11115,584,255 - 115,604,051 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123485
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,476,530 - 115,479,881 (-)Ensembl
GRCm38.p6 Ensembl11115,585,704 - 115,589,055 (-)Ensembl
Ensembl Acc Id: ENSMUST00000123831
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,478,762 - 115,494,702 (-)Ensembl
GRCm38.p6 Ensembl11115,587,936 - 115,603,876 (-)Ensembl
Ensembl Acc Id: ENSMUST00000125097   ⟹   ENSMUSP00000118024
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,482,468 - 115,494,719 (-)Ensembl
GRCm38.p6 Ensembl11115,591,642 - 115,603,893 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128437
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,476,613 - 115,494,710 (-)Ensembl
GRCm38.p6 Ensembl11115,585,787 - 115,603,884 (-)Ensembl
Ensembl Acc Id: ENSMUST00000132503
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,483,343 - 115,494,706 (-)Ensembl
GRCm38.p6 Ensembl11115,592,517 - 115,603,880 (-)Ensembl
Ensembl Acc Id: ENSMUST00000136790
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,478,411 - 115,478,853 (-)Ensembl
GRCm38.p6 Ensembl11115,587,585 - 115,588,027 (-)Ensembl
Ensembl Acc Id: ENSMUST00000148782
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,479,303 - 115,494,714 (-)Ensembl
GRCm38.p6 Ensembl11115,588,477 - 115,603,888 (-)Ensembl
Ensembl Acc Id: ENSMUST00000149814
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,483,325 - 115,494,550 (-)Ensembl
GRCm38.p6 Ensembl11115,592,499 - 115,603,724 (-)Ensembl
Ensembl Acc Id: ENSMUST00000154832
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,475,190 - 115,480,347 (-)Ensembl
GRCm38.p6 Ensembl11115,584,364 - 115,589,521 (-)Ensembl
Ensembl Acc Id: ENSMUST00000156173   ⟹   ENSMUSP00000138597
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11115,475,081 - 115,494,877 (-)Ensembl
GRCm38.p6 Ensembl11115,584,255 - 115,604,051 (-)Ensembl
RefSeq Acc Id: NM_001252067   ⟹   NP_001238996
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,494,711 (-)NCBI
GRCm3811115,584,255 - 115,603,916 (-)NCBI
Celera11127,352,022 - 127,371,690 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_173048   ⟹   NP_766636
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,494,711 (-)NCBI
GRCm3811115,584,255 - 115,603,916 (-)NCBI
MGSCv3711115,445,569 - 115,465,220 (-)RGD
Celera11127,352,022 - 127,371,690 (-)ENTREZGENE
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006533365   ⟹   XP_006533428
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,494,927 (-)NCBI
GRCm3811115,584,255 - 115,604,065 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249031   ⟹   XP_011247333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,494,727 (-)NCBI
GRCm3811115,584,255 - 115,603,901 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011249032   ⟹   XP_011247334
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,482,481 (-)NCBI
GRCm3811115,584,255 - 115,591,655 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004936965
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,495,501 (-)NCBI
Sequence:
RefSeq Acc Id: XR_388465
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911115,475,081 - 115,495,501 (-)NCBI
GRCm3811115,584,255 - 115,604,517 (-)NCBI
Sequence:
RefSeq Acc Id: NP_766636   ⟸   NM_173048
- Peptide Label: isoform 1
- UniProtKB: Q3V1Y0 (UniProtKB/Swiss-Prot),   Q80U71 (UniProtKB/Swiss-Prot),   Q8BMI3 (UniProtKB/Swiss-Prot),   S4R2D2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001238996   ⟸   NM_001252067
- Peptide Label: isoform 2
- UniProtKB: A2A9W7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006533428   ⟸   XM_006533365
- Peptide Label: isoform X1
- UniProtKB: S4R2D2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011247333   ⟸   XM_011249031
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011247334   ⟸   XM_011249032
- Peptide Label: isoform X3
- Sequence:
GAE   GAT   VHS

Name Modeler Protein Id AA Range Protein Structure
AF-Q8BMI3-F1-model_v2 AlphaFold Q8BMI3 1-718 view protein structure

RGD ID:6820938
Promoter ID:MM_KWN:10544
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000014296
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611115,449,101 - 115,449,752 (-)MPROMDB
RGD ID:6820934
Promoter ID:MM_KWN:10547
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   BoneMarrow_0Hour,   Brain,   Liver,   Lung,   Spleen
Transcripts:OTTMUST00000007400,   OTTMUST00000007401,   OTTMUST00000007402,   OTTMUST00000007403,   OTTMUST00000007404,   OTTMUST00000007405,   OTTMUST00000007406,   OTTMUST00000014297,   OTTMUST00000014298
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3611115,464,946 - 115,465,446 (-)MPROMDB
RGD ID:8677360
Promoter ID:EPDNEW_M16711
Type:single initiation site
Name:Gga3_2
Description:Mus musculus golgi associated, gamma adaptin ear containing,ARF binding protein 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16712  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811115,590,858 - 115,590,918EPDNEW
RGD ID:8677362
Promoter ID:EPDNEW_M16712
Type:multiple initiation site
Name:Gga3_1
Description:Mus musculus golgi associated, gamma adaptin ear containing,ARF binding protein 3 , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M16711  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811115,603,883 - 115,603,943EPDNEW


1 to 40 of 47 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000020740 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000019135 ENTREZGENE
  ENSMUST00000019135.14 UniProtKB/Swiss-Prot
  ENSMUST00000106508 ENTREZGENE
  ENSMUST00000156173 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  1.20.58.160 UniProtKB/Swiss-Prot
  1.25.40.90 UniProtKB/Swiss-Prot
  2.60.40.1230 UniProtKB/Swiss-Prot
InterPro Clathrin_a/b/g-adaptin_app_Ig UniProtKB/Swiss-Prot
  Clathrin_app_Ig-like_sf UniProtKB/Swiss-Prot
  ENTH_VHS UniProtKB/Swiss-Prot
  GAE_dom UniProtKB/Swiss-Prot
  GAT_dom UniProtKB/Swiss-Prot
  GAT_GGA3 UniProtKB/Swiss-Prot
  GAT_sf UniProtKB/Swiss-Prot
  GGA3 UniProtKB/Swiss-Prot
  GGA_N-GAT UniProtKB/Swiss-Prot
  VHS_dom UniProtKB/Swiss-Prot
  VHS_GGA3 UniProtKB/Swiss-Prot
KEGG Report mmu:260302 UniProtKB/Swiss-Prot
MGD MGI:2384159 ENTREZGENE
NCBI Gene 260302 ENTREZGENE
PANTHER GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN UniProtKB/Swiss-Prot
  PTHR45905:SF3 UniProtKB/Swiss-Prot
Pfam Alpha_adaptinC2 UniProtKB/Swiss-Prot
  GAT UniProtKB/Swiss-Prot
  GGA_N-GAT UniProtKB/Swiss-Prot
  VHS UniProtKB/Swiss-Prot
PhenoGen Gga3 PhenoGen
PROSITE GAE UniProtKB/Swiss-Prot
  GAT UniProtKB/Swiss-Prot
  VHS UniProtKB/Swiss-Prot
SMART Alpha_adaptinC2 UniProtKB/Swiss-Prot
  VHS UniProtKB/Swiss-Prot
Superfamily-SCOP GAT-like domain UniProtKB/Swiss-Prot
  SSF48464 UniProtKB/Swiss-Prot
  SSF49348 UniProtKB/Swiss-Prot
UniProt A2A9W5_MOUSE UniProtKB/TrEMBL
  A2A9W7 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 47 rows