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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sncaip | Mouse | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | EXP | | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:15329391 | Sncaip | Mouse | 17beta-estradiol | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of SNCAIP mRNA and [Progesterone co-treated with Estradiol] results in decreased expression of SNCAIP mRNA | CTD | PMID:17404688 and PMID:30165855 | Sncaip | Mouse | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:27291303 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SNCAIP mRNA | CTD | PMID:19933214 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SNCAIP mRNA | CTD | PMID:33387578 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of SNCAIP protein] | CTD | PMID:28621812 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SNCAIP protein | CTD | PMID:28621812 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SNCAIP mRNA | CTD | PMID:21570461 | Sncaip | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SNCAIP mRNA | CTD | PMID:22298810 | Sncaip | Mouse | 4,4'-sulfonyldiphenol | increases expression | EXP | | 6480464 | bisphenol S results in increased expression of SNCAIP mRNA | CTD | PMID:30951980 | Sncaip | Mouse | 4-hydroxyphenyl retinamide | increases expression | EXP | | 6480464 | Fenretinide results in increased expression of SNCAIP mRNA | CTD | PMID:28973697 | Sncaip | Mouse | 6-propyl-2-thiouracil | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of SNCAIP mRNA | CTD | PMID:24780913 | Sncaip | Mouse | aflatoxin B1 | decreases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of SNCAIP gene | CTD | PMID:27153756 | Sncaip | Mouse | aflatoxin B1 | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SNCAIP intron and Aflatoxin B1 results in increased methylation of SNCAIP promoter | CTD | PMID:30157460 | Sncaip | Mouse | Aflatoxin B2 alpha | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of SNCAIP intron | CTD | PMID:30157460 | Sncaip | Mouse | all-trans-retinoic acid | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Tretinoin results in increased expression of SNCAIP mRNA | CTD | PMID:23724009 | Sncaip | Mouse | antirheumatic drug | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SNCAIP mRNA | CTD | PMID:24449571 | Sncaip | Mouse | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of SNCAIP mRNA | CTD | PMID:21569818 | Sncaip | Mouse | benzo[a]pyrene | affects methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SNCAIP 5' UTR and Benzo(a)pyrene affects the methylation of SNCAIP intron | CTD | PMID:27901495 and PMID:30157460 | Sncaip | Mouse | benzo[a]pyrene | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SNCAIP promoter | CTD | PMID:27901495 | Sncaip | Mouse | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Sncaip | Mouse | benzo[e]pyrene | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SNCAIP intron | CTD | PMID:30157460 | Sncaip | Mouse | bisphenol A | decreases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of SNCAIP mRNA | CTD | PMID:25181051 and PMID:26186136 | Sncaip | Mouse | bisphenol A | decreases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of SNCAIP gene | CTD | PMID:31601247 | Sncaip | Mouse | bisphenol A | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of SNCAIP mRNA | CTD | PMID:34947998 | Sncaip | Mouse | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SNCAIP mRNA | CTD | PMID:30951980 | Sncaip | Mouse | bisphenol A | increases methylation | ISO | Sncaip (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of SNCAIP gene | CTD | PMID:28505145 | Sncaip | Mouse | bisphenol F | decreases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | 4 and 4'-bisphenol F results in decreased expression of SNCAIP mRNA | CTD | PMID:26186136 | Sncaip | Mouse | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of SNCAIP mRNA | CTD | PMID:30951980 | Sncaip | Mouse | buta-1,3-diene | decreases expression | EXP | | 6480464 | 1 and 3-butadiene results in decreased expression of SNCAIP mRNA | CTD | PMID:29038090 | Sncaip | Mouse | cadmium dichloride | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SNCAIP mRNA | CTD | PMID:38568856 | Sncaip | Mouse | calcitriol | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SNCAIP mRNA | CTD | PMID:16002434 | Sncaip | Mouse | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon results in decreased expression of SNCAIP mRNA | CTD | PMID:25554681 | Sncaip | Mouse | CGP 52608 | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SNCAIP gene] | CTD | PMID:28238834 | Sncaip | Mouse | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of SNCAIP mRNA | CTD | PMID:32715474 | Sncaip | Mouse | chromium(6+) | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of SNCAIP mRNA | CTD | PMID:38479592 | Sncaip | Mouse | cocaine | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Cocaine results in increased expression of SNCAIP mRNA | CTD | PMID:16459018 | Sncaip | Mouse | copper atom | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of SNCAIP mRNA | CTD | PMID:26033743 | Sncaip | Mouse | copper(0) | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Copper deficiency results in increased expression of SNCAIP mRNA | CTD | PMID:26033743 | Sncaip | Mouse | copper(II) chloride | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | cupric chloride results in decreased expression of SNCAIP mRNA | CTD | PMID:38568856 | Sncaip | Mouse | Cuprizon | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Cuprizone results in increased expression of SNCAIP mRNA | CTD | PMID:26577399 | Sncaip | Mouse | cyclosporin A | decreases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of SNCAIP promoter | CTD | PMID:27989131 | Sncaip | Mouse | dorsomorphin | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Sncaip | Mouse | entinostat | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | entinostat results in decreased expression of SNCAIP mRNA | CTD | PMID:27188386 | Sncaip | Mouse | fenvalerate | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of SNCAIP mRNA | CTD | PMID:30307764 | Sncaip | Mouse | fulvestrant | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of SNCAIP gene | CTD | PMID:31601247 | Sncaip | Mouse | furan | increases methylation | ISO | Sncaip (Rattus norvegicus) | 6480464 | furan results in increased methylation of SNCAIP gene | CTD | PMID:22079235 | Sncaip | Mouse | gentamycin | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of SNCAIP mRNA | CTD | PMID:33387578 | Sncaip | Mouse | lead diacetate | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | lead acetate results in decreased expression of SNCAIP mRNA | CTD | PMID:38568856 | Sncaip | Mouse | mercury dibromide | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of SNCAIP mRNA | CTD | PMID:26272509 | Sncaip | Mouse | mercury dibromide | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA | CTD | PMID:27188386 | Sncaip | Mouse | mercury dichloride | increases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Mercuric Chloride results in increased expression of SNCAIP mRNA | CTD | PMID:32599119 | Sncaip | Mouse | methapyrilene | increases methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SNCAIP intron | CTD | PMID:30157460 | Sncaip | Mouse | methylmercury chloride | increases expression | EXP | | 6480464 | methylmercuric chloride results in increased expression of SNCAIP mRNA | CTD | PMID:20061341 | Sncaip | Mouse | methylmercury chloride | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SNCAIP mRNA | CTD | PMID:28001369 | Sncaip | Mouse | methylphenidate | increases expression | EXP | | 6480464 | Methylphenidate results in increased expression of SNCAIP mRNA | CTD | PMID:22470460 | Sncaip | Mouse | nitrobenzenes | affects response to substance | ISO | SNCAIP (Homo sapiens) | 6480464 | SNCAIP gene SNP affects the susceptibility to Nitrobenzenes analog | CTD | PMID:25622337 | Sncaip | Mouse | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of SNCAIP mRNA | CTD | PMID:27106289 | Sncaip | Mouse | p-chloromercuribenzoic acid | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of SNCAIP mRNA | CTD | PMID:26272509 | Sncaip | Mouse | p-chloromercuribenzoic acid | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA | CTD | PMID:27188386 | Sncaip | Mouse | paracetamol | decreases expression | ISO | Sncaip (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of SNCAIP mRNA | CTD | PMID:33387578 | Sncaip | Mouse | phenylmercury acetate | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of SNCAIP mRNA | CTD | PMID:26272509 | Sncaip | Mouse | phenylmercury acetate | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA | CTD | PMID:27188386 | Sncaip | Mouse | pioglitazone | multiple interactions | EXP | | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SNCAIP mRNA | CTD | PMID:27935865 | Sncaip | Mouse | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of SNCAIP mRNA | CTD | PMID:20813756 and PMID:23811191 | Sncaip | Mouse | progesterone | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [Progesterone co-treated with Estradiol] results in decreased expression of SNCAIP mRNA | CTD | PMID:17404688 | Sncaip | Mouse | rotenone | multiple interactions | EXP | | 6480464 | SNCAIP protein inhibits the reaction [Rotenone results in increased activity of CASP3 protein] and SNCAIP protein inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] | CTD | PMID:19857556 | Sncaip | Mouse | SB 431542 | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Sncaip | Mouse | sodium arsenite | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SNCAIP mRNA | CTD | PMID:20371982 more ... | Sncaip | Mouse | sodium arsenite | affects methylation | ISO | SNCAIP (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of SNCAIP gene | CTD | PMID:28589171 | Sncaip | Mouse | sunitinib | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SNCAIP mRNA | CTD | PMID:31533062 | Sncaip | Mouse | thimerosal | multiple interactions | ISO | SNCAIP (Homo sapiens) | 6480464 | [NOG protein co-treated with Thimerosal co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SNCAIP mRNA | CTD | PMID:27188386 | Sncaip | Mouse | titanium dioxide | decreases methylation | EXP | | 6480464 | titanium dioxide results in decreased methylation of SNCAIP gene | CTD | PMID:35295148 | Sncaip | Mouse | trichostatin A | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | trichostatin A results in increased expression of SNCAIP mRNA | CTD | PMID:24935251 | Sncaip | Mouse | trimellitic anhydride | decreases expression | EXP | | 6480464 | trimellitic anhydride results in decreased expression of SNCAIP mRNA | CTD | PMID:19042947 | Sncaip | Mouse | valproic acid | affects expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SNCAIP mRNA | CTD | PMID:25979313 | Sncaip | Mouse | valproic acid | increases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SNCAIP mRNA | CTD | PMID:24935251 and PMID:26272509 | Sncaip | Mouse | versicolorin A | decreases expression | ISO | SNCAIP (Homo sapiens) | 6480464 | versicolorin A results in decreased expression of SNCAIP mRNA | CTD | PMID:32106047 | |