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Gene: TTC9 (tetratricopeptide repeat domain 9) Homo sapiens

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Symbol:

TTC9

Name:

tetratricopeptide repeat domain 9

RGD ID:

1318967

HGNC Page

HGNC:20267

Description:

Predicted to act upstream of or within bone development. Implicated in opiate dependence.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

KIAA0227; tetratricopeptide repeat protein 9A; TPR repeat protein 9A; TTC9A

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Ttc9 (tetratricopeptide repeat domain 9)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Ttc9 (tetratricopeptide repeat domain 9)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Chinchilla lanigera (long-tailed chinchilla):	Ttc9 (tetratricopeptide repeat domain 9)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	TTC9 (tetratricopeptide repeat domain 9)	NCBI	Ortholog
Canis lupus familiaris (dog):	TTC9 (tetratricopeptide repeat domain 9)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ttc9 (tetratricopeptide repeat domain 9)	NCBI	Ortholog
Sus scrofa (pig):	TTC9 (tetratricopeptide repeat domain 9)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	TTC9 (tetratricopeptide repeat domain 9)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Ttc9 (tetratricopeptide repeat domain 9)	NCBI	Ortholog
Alliance orthologs ³
Mus musculus (house mouse):	Ttc9 (tetratricopeptide repeat domain 9)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Rattus norvegicus (Norway rat):	Ttc9 (tetratricopeptide repeat domain 9)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	ttc9.L	Alliance	DIOPT (Xenbase)
Xenopus tropicalis (tropical clawed frog):	ttc9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus laevis (African clawed frog):	ttc9.S	Alliance	DIOPT (Xenbase)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	70,641,916 - 70,675,366 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	70,641,916 - 70,675,366 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	71,108,633 - 71,142,083 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	70,178,257 - 70,211,830 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	51,172,455 - 51,206,028 (+)	NCBI		Celera
Cytogenetic Map	14	q24.2	NCBI
HuRef	14	51,277,148 - 51,310,717 (+)	NCBI		HuRef
CHM1_1	14	71,046,680 - 71,080,246 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	64,847,902 - 64,881,350 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC9	Human	opiate dependence	susceptibility	IAGP		401851917	DNA:SNP:: (rs8688) (human)	RGD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC9	Human	opiate dependence		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:18438686

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC9	Human	(+)-schisandrin B	multiple interactions	ISO	RGD:1565985	6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TTC9 mRNA]	CTD	PMID:31150632
TTC9	Human	1,2-dichloroethane	decreases expression	ISO	RGD:1551119	6480464	ethylene dichloride results in decreased expression of TTC9 mRNA	CTD	PMID:28960355
TTC9	Human	17alpha-ethynylestradiol	increases expression	ISO	RGD:1565985	6480464	Ethinyl Estradiol results in increased expression of TTC9 mRNA	CTD	PMID:29097150
TTC9	Human	17beta-estradiol	multiple interactions	EXP		6480464	[Estradiol co-treated with TGFB1 protein] results in decreased expression of TTC9 mRNA	CTD	PMID:30165855
TTC9	Human	2,3,7,8-tetrachlorodibenzodioxine	affects expression	EXP		6480464	Tetrachlorodibenzodioxin affects the expression of TTC9 mRNA	CTD	PMID:22298810
TTC9	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1565985	6480464	Tetrachlorodibenzodioxin results in decreased expression of TTC9 mRNA	CTD	PMID:32109520
TTC9	Human	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1565985	6480464	Tetrachlorodibenzodioxin affects the expression of TTC9 mRNA	CTD	PMID:22298810
TTC9	Human	4,4'-sulfonyldiphenol	affects methylation	ISO	RGD:1551119	6480464	bisphenol S affects the methylation of TTC9 gene	CTD	PMID:31683443
TTC9	Human	4-hydroxyphenyl retinamide	increases expression	ISO	RGD:1551119	6480464	Fenretinide results in increased expression of TTC9 mRNA	CTD	PMID:28973697
TTC9	Human	6-propyl-2-thiouracil	increases expression	ISO	RGD:1565985	6480464	Propylthiouracil results in increased expression of TTC9 mRNA	CTD	PMID:30047161
TTC9	Human	8-Br-cAMP	increases expression	EXP		6480464	8-Bromo Cyclic Adenosine Monophosphate results in increased expression of TTC9 mRNA	CTD	PMID:22079614
TTC9	Human	aflatoxin B1	increases expression	ISO	RGD:1565985	6480464	Aflatoxin B1 results in increased expression of TTC9 mRNA	CTD	PMID:23630614
TTC9	Human	aflatoxin B1	decreases methylation	EXP		6480464	Aflatoxin B1 results in decreased methylation of TTC9 intron	CTD	PMID:30157460
TTC9	Human	all-trans-retinoic acid	increases expression	EXP		6480464	Tretinoin results in increased expression of TTC9 mRNA	CTD	PMID:23724009
TTC9	Human	amitrole	increases expression	ISO	RGD:1565985	6480464	Amitrole results in increased expression of TTC9 mRNA	CTD	PMID:30047161
TTC9	Human	atrazine	affects methylation	ISO	RGD:1565985	6480464	Atrazine affects the methylation of TTC9 gene	CTD	PMID:35440735
TTC9	Human	benzo[a]pyrene	affects methylation	EXP		6480464	Benzo(a)pyrene affects the methylation of TTC9 promoter	CTD	PMID:27901495
TTC9	Human	bisphenol A	affects expression	ISO	RGD:1565985	6480464	bisphenol A affects the expression of TTC9 mRNA	CTD	PMID:25181051
TTC9	Human	bisphenol A	increases expression	ISO	RGD:1551119	6480464	bisphenol A results in increased expression of TTC9 mRNA	CTD	PMID:32156529
TTC9	Human	bisphenol A	decreases expression	EXP		6480464	bisphenol A analog results in decreased expression of TTC9 mRNA	CTD	PMID:32387340
TTC9	Human	bisphenol A	increases methylation	ISO	RGD:1565985	6480464	bisphenol A results in increased methylation of TTC9 gene	CTD	PMID:28505145
TTC9	Human	cadmium atom	increases expression	EXP		6480464	Cadmium results in increased expression of TTC9 mRNA	CTD	PMID:21120746
TTC9	Human	cadmium dichloride	increases expression	EXP		6480464	Cadmium Chloride results in increased expression of TTC9 mRNA	CTD	PMID:38568856
TTC9	Human	calcitriol	increases expression	EXP		6480464	Calcitriol results in increased expression of TTC9 mRNA	CTD	PMID:26485663
TTC9	Human	carbon nanotube	increases expression	ISO	RGD:1551119	6480464	Nanotubes, Carbon analog results in increased expression of TTC9 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
TTC9	Human	chloroprene	increases expression	ISO	RGD:1551119	6480464	Chloroprene results in increased expression of TTC9 mRNA	CTD	PMID:23125180
TTC9	Human	cisplatin	multiple interactions	ISO	RGD:1551119	6480464	[Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in increased expression of more ...	CTD	PMID:23625948
TTC9	Human	cisplatin	decreases expression	EXP		6480464	Cisplatin results in decreased expression of TTC9 mRNA	CTD	PMID:27392435
TTC9	Human	copper(II) sulfate	increases expression	EXP		6480464	Copper Sulfate results in increased expression of TTC9 mRNA	CTD	PMID:19549813
TTC9	Human	corosolic acid	increases expression	EXP		6480464	corosolic acid results in increased expression of TTC9 mRNA	CTD	PMID:37939859
TTC9	Human	coumestrol	multiple interactions	EXP		6480464	[Coumestrol co-treated with resveratrol] results in decreased expression of TTC9 mRNA	CTD	PMID:19167446
TTC9	Human	coumestrol	decreases expression	EXP		6480464	Coumestrol results in decreased expression of TTC9 mRNA	CTD	PMID:19167446
TTC9	Human	Cuprizon	decreases expression	ISO	RGD:1565985	6480464	Cuprizone results in decreased expression of TTC9 mRNA	CTD	PMID:26577399
TTC9	Human	cyclosporin A	increases expression	EXP		6480464	Cyclosporine results in increased expression of TTC9 mRNA	CTD	PMID:25562108
TTC9	Human	dibutyl phthalate	decreases expression	ISO	RGD:1565985	6480464	Dibutyl Phthalate results in decreased expression of TTC9 mRNA	CTD	PMID:21266533
TTC9	Human	dioxygen	multiple interactions	ISO	RGD:1565985	6480464	[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression more ...	CTD	PMID:33729688
TTC9	Human	diuron	decreases expression	ISO	RGD:1565985	6480464	Diuron results in decreased expression of TTC9 mRNA	CTD	PMID:21551480
TTC9	Human	dorsomorphin	multiple interactions	EXP		6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
TTC9	Human	doxorubicin	decreases expression	EXP		6480464	Doxorubicin results in decreased expression of TTC9 mRNA	CTD	PMID:29803840
TTC9	Human	endosulfan	increases expression	ISO	RGD:1565985	6480464	Endosulfan results in increased expression of TTC9 mRNA	CTD	PMID:29391264
TTC9	Human	fenvalerate	increases expression	ISO	RGD:1565985	6480464	fenvalerate results in increased expression of TTC9 mRNA	CTD	PMID:30307764
TTC9	Human	furan	increases expression	ISO	RGD:1565985	6480464	furan results in increased expression of TTC9 mRNA	CTD	PMID:27387713
TTC9	Human	kojic acid	increases expression	EXP		6480464	kojic acid results in increased expression of TTC9 mRNA	CTD	PMID:16595896
TTC9	Human	lead(0)	affects expression	EXP		6480464	Lead affects the expression of TTC9 mRNA	CTD	PMID:28903495
TTC9	Human	malathion	decreases expression	EXP		6480464	Malathion results in decreased expression of TTC9 mRNA	CTD	PMID:37047231
TTC9	Human	methimazole	increases expression	ISO	RGD:1565985	6480464	Methimazole results in increased expression of TTC9 mRNA	CTD	PMID:30047161
TTC9	Human	N-methyl-4-phenylpyridinium	decreases expression	EXP		6480464	1-Methyl-4-phenylpyridinium results in decreased expression of TTC9 mRNA	CTD	PMID:24810058
TTC9	Human	nickel atom	increases expression	EXP		6480464	Nickel results in increased expression of TTC9 mRNA	CTD	PMID:25583101
TTC9	Human	okadaic acid	increases expression	EXP		6480464	Okadaic Acid results in increased expression of TTC9 mRNA	CTD	PMID:38832940
TTC9	Human	ozone	multiple interactions	ISO	RGD:1551119	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ...	CTD	PMID:34911549
TTC9	Human	paracetamol	affects expression	ISO	RGD:1551119	6480464	Acetaminophen affects the expression of TTC9 mRNA	CTD	PMID:17562736
TTC9	Human	paracetamol	increases expression	ISO	RGD:1565985	6480464	Acetaminophen results in increased expression of TTC9 mRNA	CTD	PMID:33387578
TTC9	Human	paraquat	increases expression	ISO	RGD:1565985	6480464	Paraquat results in increased expression of TTC9 mRNA	CTD	PMID:32680482
TTC9	Human	perfluorohexanesulfonic acid	increases expression	ISO	RGD:1551119	6480464	perfluorohexanesulfonic acid results in increased expression of TTC9 mRNA	CTD	PMID:37995155
TTC9	Human	phenylmercury acetate	increases expression	EXP		6480464	Phenylmercuric Acetate results in increased expression of TTC9 mRNA	CTD	PMID:26272509
TTC9	Human	phenylmercury acetate	multiple interactions	EXP		6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
TTC9	Human	pirinixic acid	increases expression	ISO	RGD:1551119	6480464	pirinixic acid results in increased expression of TTC9 mRNA	CTD	PMID:21318169
TTC9	Human	pirinixic acid	multiple interactions	ISO	RGD:1551119	6480464	PPARA protein affects the reaction [pirinixic acid results in increased expression of TTC9 mRNA]	CTD	PMID:21318169
TTC9	Human	pregnenolone 16alpha-carbonitrile	increases expression	ISO	RGD:1565985	6480464	Pregnenolone Carbonitrile results in increased expression of TTC9 mRNA	CTD	PMID:30047161
TTC9	Human	resveratrol	multiple interactions	EXP		6480464	[Coumestrol co-treated with resveratrol] results in decreased expression of TTC9 mRNA	CTD	PMID:19167446
TTC9	Human	SB 431542	multiple interactions	EXP		6480464	[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ...	CTD	PMID:27188386
TTC9	Human	sodium arsenite	increases expression	EXP		6480464	sodium arsenite results in increased expression of TTC9 mRNA	CTD	PMID:38568856
TTC9	Human	Soman	increases expression	ISO	RGD:1565985	6480464	Soman results in increased expression of TTC9 mRNA	CTD	PMID:19281266
TTC9	Human	sulfadimethoxine	increases expression	ISO	RGD:1565985	6480464	Sulfadimethoxine results in increased expression of TTC9 mRNA	CTD	PMID:30047161
TTC9	Human	testosterone enanthate	affects expression	EXP		6480464	testosterone enanthate affects the expression of TTC9 mRNA	CTD	PMID:17440010
TTC9	Human	tetrachloromethane	increases expression	ISO	RGD:1565985	6480464	Carbon Tetrachloride results in increased expression of TTC9 mRNA	CTD	PMID:31150632
TTC9	Human	tetrachloromethane	multiple interactions	ISO	RGD:1565985	6480464	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of TTC9 mRNA]	CTD	PMID:31150632
TTC9	Human	thioacetamide	increases expression	ISO	RGD:1565985	6480464	Thioacetamide results in increased expression of TTC9 mRNA	CTD	PMID:23411599\|PMID:34492290
TTC9	Human	titanium dioxide	decreases expression	ISO	RGD:1551119	6480464	titanium dioxide results in decreased expression of TTC9 mRNA	CTD	PMID:23557971
TTC9	Human	titanium dioxide	decreases methylation	ISO	RGD:1551119	6480464	titanium dioxide results in decreased methylation of TTC9 gene	CTD	PMID:35295148
TTC9	Human	triphenyl phosphate	affects expression	EXP		6480464	triphenyl phosphate affects the expression of TTC9 mRNA	CTD	PMID:37042841
TTC9	Human	valproic acid	increases expression	EXP		6480464	Valproic Acid results in increased expression of TTC9 mRNA	CTD	PMID:19101580\|PMID:27188386
TTC9	Human	zoledronic acid	increases expression	EXP		6480464	zoledronic acid results in increased expression of TTC9 mRNA	CTD	PMID:24714768

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC9	Human	bone development	acts_upstream_of_or_within	IEA	UniProtKB:Q3V038\|ensembl:ENSMUSP00000152038	150520179		Ensembl	GO_REF:0000107

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC9	Human	Addictive opioid use	susceptibility	IAGP		401851917	DNA:SNP:: (rs8688) (human)	RGD

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Substance dependence low-density whole genome association study in two distinct American populations.	Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.

PMID:9039502	PMID:12477932	PMID:15489334	PMID:16678794	PMID:18699990	PMID:22917536	PMID:25217961	PMID:25798063	PMID:30021884	PMID:30325323	PMID:33961781	PMID:35063084
PMID:35831314	PMID:35906200	PMID:38293978

TTC9
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	70,641,916 - 70,675,366 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	70,641,916 - 70,675,366 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	71,108,633 - 71,142,083 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	70,178,257 - 70,211,830 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	51,172,455 - 51,206,028 (+)	NCBI		Celera
Cytogenetic Map	14	q24.2	NCBI
HuRef	14	51,277,148 - 51,310,717 (+)	NCBI		HuRef
CHM1_1	14	71,046,680 - 71,080,246 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	64,847,902 - 64,881,350 (+)	NCBI		T2T-CHM13v2.0

Ttc9
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	81,678,023 - 81,714,331 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	81,678,023 - 81,714,331 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	81,631,249 - 81,667,557 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	81,631,249 - 81,667,557 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	82,732,356 - 82,765,928 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	82,550,217 - 82,583,789 (+)	NCBI		MGSCv36	mm8
Celera	12	83,098,495 - 83,131,977 (+)	NCBI		Celera
Cytogenetic Map	12	D1	NCBI
cM Map	12	37.85	NCBI

Ttc9
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	107,064,527 - 107,099,361 (+)	NCBI		GRCr8
mRatBN7.2	6	101,333,274 - 101,368,110 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	101,333,141 - 101,368,110 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	101,484,199 - 101,519,018 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	101,783,388 - 101,818,207 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	101,154,399 - 101,189,235 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	105,364,668 - 105,399,500 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	105,364,668 - 105,399,500 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	113,510,835 - 113,545,667 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	105,495,936 - 105,530,999 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	99,168,031 - 99,202,888 (+)	NCBI		Celera
Cytogenetic Map	6	q24	NCBI

Ttc9
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955523	4,438,674 - 4,471,049 (-)	NCBI	ChiLan1.0	ChiLan1.0

TTC9
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	71,760,138 - 71,793,953 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	70,976,652 - 71,010,466 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	51,229,734 - 51,262,455 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	70,100,391 - 70,132,551 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	70,100,391 - 70,130,915 (+)	Ensembl	panpan1.1		panPan2

TTC9
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	44,358,130 - 44,392,062 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	44,357,641 - 44,387,737 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	44,021,651 - 44,055,504 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	44,580,694 - 44,614,521 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	44,580,694 - 44,613,616 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	44,234,500 - 44,274,511 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	44,279,640 - 44,313,502 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	44,640,561 - 44,674,646 (+)	NCBI		UU_Cfam_GSD_1.0

Ttc9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	31,757,305 - 31,796,572 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936488	302,502 - 311,483 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTC9
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	94,218,649 - 94,254,730 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	94,218,436 - 94,254,472 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	100,537,831 - 100,574,711 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTC9
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	47,845,463 - 47,878,891 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	47,846,449 - 47,877,325 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	36,067,908 - 36,102,438 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ttc9
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	30,532,480 - 30,559,914 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	30,503,322 - 30,560,074 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in TTC9
17 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 14q24.1-31.1(chr14:69562099-81975384)x1	copy number loss	See cases [RCV000134154]	Chr14:69562099..81975384 [GRCh38] Chr14:70028816..82441728 [GRCh37] Chr14:69098569..81511481 [NCBI36] Chr14:14q24.1-31.1	pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3	copy number gain	See cases [RCV000135543]	Chr14:20151149..106855263 [GRCh38] Chr14:20619308..107263478 [GRCh37] Chr14:19689148..106334523 [NCBI36] Chr14:14q11.2-32.33	pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3	copy number gain	See cases [RCV000143373]	Chr14:20043514..106877229 [GRCh38] Chr14:20511673..107285437 [GRCh37] Chr14:19581513..106356482 [NCBI36] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3	copy number gain	See cases [RCV000446256]	Chr14:19794561..107234280 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q23.2-32.33(chr14:62493932-107285437)x3	copy number gain	See cases [RCV000448557]	Chr14:62493932..107285437 [GRCh37] Chr14:14q23.2-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437)	copy number gain	See cases [RCV000512041]	Chr14:20511673..107285437 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q24.1-24.2(chr14:68035240-73568130)x1	copy number loss	See cases [RCV000512344]	Chr14:68035240..73568130 [GRCh37] Chr14:14q24.1-24.2	likely pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3	copy number gain	not provided [RCV000738412]	Chr14:19000422..107289053 [GRCh37] Chr14:14q11.1-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3	copy number gain	not provided [RCV000738413]	Chr14:19280733..107287663 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3	copy number gain	not provided [RCV000738414]	Chr14:19327823..107287663 [GRCh37] Chr14:14q11.2-32.33	pathogenic
GRCh37/hg19 14q24.2(chr14:71040157-71240681)x3	copy number gain	not provided [RCV000751048]	Chr14:71040157..71240681 [GRCh37] Chr14:14q24.2	benign
GRCh37/hg19 14q24.2(chr14:71139279-71598042)x3	copy number gain	not provided [RCV000751049]	Chr14:71139279..71598042 [GRCh37] Chr14:14q24.2	benign
GRCh37/hg19 14q22.2-24.3(chr14:54654001-75828024)x3	copy number gain	14q22.2q24.3 duplication [RCV001506967]	Chr14:54654001..75828024 [GRCh37] Chr14:14q22.2-24.3	likely pathogenic
GRCh37/hg19 14q13.3-32.33(chr14:37671058-106985955)x2	copy number gain	See cases [RCV002286356]	Chr14:37671058..106985955 [GRCh37] Chr14:14q13.3-32.33	pathogenic
NM_015351.2(TTC9):c.329T>C (p.Leu110Pro)	single nucleotide variant	not specified [RCV004194827]	Chr14:70642458 [GRCh38] Chr14:71109175 [GRCh37] Chr14:14q24.2	likely benign
NM_015351.2(TTC9):c.352G>A (p.Glu118Lys)	single nucleotide variant	not specified [RCV004153257]	Chr14:70642481 [GRCh38] Chr14:71109198 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.481G>C (p.Gly161Arg)	single nucleotide variant	not specified [RCV004098440]	Chr14:70667638 [GRCh38] Chr14:71134355 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.23C>G (p.Ala8Gly)	single nucleotide variant	not specified [RCV004196585]	Chr14:70642152 [GRCh38] Chr14:71108869 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.193G>A (p.Ala65Thr)	single nucleotide variant	not specified [RCV004329153]	Chr14:70642322 [GRCh38] Chr14:71109039 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.122G>A (p.Arg41Lys)	single nucleotide variant	not specified [RCV004353164]	Chr14:70642251 [GRCh38] Chr14:71108968 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.17C>T (p.Ser6Leu)	single nucleotide variant	not specified [RCV004362555]	Chr14:70642146 [GRCh38] Chr14:71108863 [GRCh37] Chr14:14q24.2	uncertain significance
GRCh37/hg19 14q23.1-32.33(chr14:58894502-107227240)x3	copy number gain	not provided [RCV003485036]	Chr14:58894502..107227240 [GRCh37] Chr14:14q23.1-32.33	pathogenic
NM_015351.2(TTC9):c.596A>G (p.Asn199Ser)	single nucleotide variant	not specified [RCV004479292]	Chr14:70671082 [GRCh38] Chr14:71137799 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.284G>C (p.Gly95Ala)	single nucleotide variant	not specified [RCV004479288]	Chr14:70642413 [GRCh38] Chr14:71109130 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.308C>T (p.Pro103Leu)	single nucleotide variant	not specified [RCV004479289]	Chr14:70642437 [GRCh38] Chr14:71109154 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.550C>T (p.Leu184Phe)	single nucleotide variant	not specified [RCV004479291]	Chr14:70667707 [GRCh38] Chr14:71134424 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.625A>T (p.Met209Leu)	single nucleotide variant	not specified [RCV004479293]	Chr14:70671111 [GRCh38] Chr14:71137828 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.458G>A (p.Cys153Tyr)	single nucleotide variant	not specified [RCV004878761]	Chr14:70667615 [GRCh38] Chr14:71134332 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.544A>C (p.Lys182Gln)	single nucleotide variant	not specified [RCV004878760]	Chr14:70667701 [GRCh38] Chr14:71134418 [GRCh37] Chr14:14q24.2	uncertain significance
NM_015351.2(TTC9):c.82C>T (p.Pro28Ser)	single nucleotide variant	not specified [RCV004682725]	Chr14:70642211 [GRCh38] Chr14:71108928 [GRCh37] Chr14:14q24.2	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	1716
Count of miRNA genes:	922
Interacting mature miRNAs:	1083
Transcripts:	ENST00000256367
Prediction methods:	Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597244168	GWAS1340242_H	sarcopenia QTL GWAS1340242 (human)		0.000006	sarcopenia		14	70668226	70668227	Human
597223215	GWAS1319289_H	heel bone mineral density, urate measurement QTL GWAS1319289 (human)		8e-11	heel bone mineral density, urate measurement	blood uric acid level (CMO:0000501)	14	70653617	70653618	Human
597160092	GWAS1256166_H	3-carboxy-4-methyl-5-propyl-2-furanpropanoate CMPF measurement QTL GWAS1256166 (human)		0.000004	3-carboxy-4-methyl-5-propyl-2-furanpropanoate CMPF measurement		14	70644644	70644645	Human
597429280	GWAS1525354_H	protein measurement QTL GWAS1525354 (human)		7e-09	protein measurement		14	70671127	70671128	Human
597177975	GWAS1274049_H	tetratricopeptide repeat protein 9B measurement QTL GWAS1274049 (human)		5e-39	tetratricopeptide repeat protein 9B measurement		14	70652446	70652447	Human

G38116

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,140,433 - 71,140,589	UniSTS	GRCh37
Build 36	14	70,210,186 - 70,210,342	RGD	NCBI36
Celera	14	51,204,384 - 51,204,540	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,309,073 - 51,309,229	UniSTS

A005T47

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,141,823 - 71,142,063	UniSTS	GRCh37
Build 36	14	70,211,576 - 70,211,816	RGD	NCBI36
Celera	14	51,205,774 - 51,206,014	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,310,463 - 51,310,703	UniSTS
GeneMap99-GB4 RH Map	14	174.53	UniSTS

G20494

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,141,823 - 71,142,063	UniSTS	GRCh37
Build 36	14	70,211,576 - 70,211,816	RGD	NCBI36
Celera	14	51,205,774 - 51,206,014	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,310,463 - 51,310,703	UniSTS

G38256

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,112,906 - 71,113,142	UniSTS	GRCh37
Build 36	14	70,182,659 - 70,182,895	RGD	NCBI36
Celera	14	51,176,857 - 51,177,093	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,281,550 - 51,281,786	UniSTS

SHGC-3622

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,125,785 - 71,125,899	UniSTS	GRCh37
Build 36	14	70,195,538 - 70,195,652	RGD	NCBI36
Celera	14	51,189,737 - 51,189,851	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,294,416 - 51,294,540	UniSTS
TNG Radiation Hybrid Map	14	24972.0	UniSTS

D14S906

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,141,858 - 71,142,027	UniSTS	GRCh37
Build 36	14	70,211,611 - 70,211,780	RGD	NCBI36
Celera	14	51,205,809 - 51,205,978	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,310,498 - 51,310,667	UniSTS

RH25433

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,141,619 - 71,141,772	UniSTS	GRCh37
Build 36	14	70,211,372 - 70,211,525	RGD	NCBI36
Celera	14	51,205,570 - 51,205,723	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,310,259 - 51,310,412	UniSTS
GeneMap99-GB4 RH Map	14	174.43	UniSTS

G38244

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,138,536 - 71,138,857	UniSTS	GRCh37
Build 36	14	70,208,289 - 70,208,610	RGD	NCBI36
Celera	14	51,202,487 - 51,202,808	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,307,176 - 51,307,497	UniSTS

G20823

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,139,255 - 71,139,359	UniSTS	GRCh37
Build 36	14	70,209,008 - 70,209,112	RGD	NCBI36
Celera	14	51,203,206 - 51,203,310	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,307,895 - 51,307,999	UniSTS

A006H41

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,139,255 - 71,139,359	UniSTS	GRCh37
Build 36	14	70,209,008 - 70,209,112	RGD	NCBI36
Celera	14	51,203,206 - 51,203,310	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,307,895 - 51,307,999	UniSTS
GeneMap99-GB4 RH Map	14	174.43	UniSTS

STS-Z40406

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,139,151 - 71,139,245	UniSTS	GRCh37
Build 36	14	70,208,904 - 70,208,998	RGD	NCBI36
Celera	14	51,203,102 - 51,203,196	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,307,791 - 51,307,885	UniSTS
GeneMap99-GB4 RH Map	14	177.79	UniSTS
NCBI RH Map	14	666.1	UniSTS

WI-20573

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	14	71,139,110 - 71,139,259	UniSTS	GRCh37
Build 36	14	70,208,863 - 70,209,012	RGD	NCBI36
Celera	14	51,203,061 - 51,203,210	RGD
Cytogenetic Map	14	q24.2	UniSTS
HuRef	14	51,307,750 - 51,307,899	UniSTS
GeneMap99-GB4 RH Map	14	174.43	UniSTS
Whitehead-RH Map	14	251.9	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
1204	2432	2788	2246	4941	1722	2344	5	621	1923	463	2246	7261	6434	51	3725	848	1734	1611	175	1


RefSeq Transcripts	NG_012648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_015351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC004816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL357153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC047950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BX407741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D86980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	KF455928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000256367 ⟹ ENSP00000256367

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	14	70,641,916 - 70,675,366 (+)	Ensembl

RefSeq Acc Id:

NM_015351 ⟹ NP_056166

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	70,641,916 - 70,675,366 (+)	NCBI
GRCh37	14	71,108,504 - 71,142,077 (+)	RGD
Build 36	14	70,178,257 - 70,211,830 (+)	NCBI Archive
Celera	14	51,172,455 - 51,206,028 (+)	RGD
HuRef	14	51,277,148 - 51,310,717 (+)	ENTREZGENE
CHM1_1	14	71,046,680 - 71,080,246 (+)	NCBI
T2T-CHM13v2.0	14	64,847,902 - 64,881,350 (+)	NCBI

Sequence:

show sequence

GTCCGAGGCGGCGGCGGCGGCGGCTGGAGCAGCCTCTGGCAGCAGCGGGGAGAATGGGAGTGCGGGGCGCCAGACCGCCGCGGGGTGTCACGGCCGCCACGAAGCCTGCGAGGCGCGGGGCCGGCGCC
CGCGGCTTTTAAACCCGGGAAGGCGCGGCGGCGGCGGCGGCGGCGGGCAGATCGCGGCGCGCACCAGGCGCCGGGGCGGCGGCCGAATGGAGAGAAAGGGCTCGGCGGCCGGGGCCAAGGGGAACCCG
AGCCCGCCCGCGGCCGGAGAGGGGCAGCGGCCACCGCCGCCGCTGTGCGTCCCGGGCGGCGGCGGAGGAGCCCCAGCGAGGGGCCAGGTCGGGGCGGCGGCCGAGCCGGCCGAGCTCATCCGACGAGC
GCACGAGTTCAAAAGCCAAGGGGCGCAGTGCTACAAGGACAAGAAATTCCGTGAAGCCATAGGCAAATACCACCGGGCGTTGCTGGAGCTGAAGGGGCTGCTGCCGCCCCCCGGGGAACGGGAGCGGG
ACTCGCGCCCGGCCTCCCCGGCTGGGGCCCTGAAGCCCGGCCGCCTCTCGGAGGAGCAGAGCAAGACGGTGGAAGCCATCGAGATCGACTGTTACAACAGCCTGGCAGCCTGCCTGCTCCAGGCTGAG
CTGGTAAACTATGAACGAGTCAAGGAATATTGCCTCAAAGTCTTGAAGAAGGAAGGGGAGAACTTCAAGGCCCTTTACCGGTCTGGTGTGGCCTTCTACCACCTTGGGGACTATGACAAAGCACTCTA
CTACCTGAAAGAAGCAAGGACCCAACAACCAACAGACACCAACGTGATTCGGTATATCCAGCTGACGGAGATGAAACTCAGCCGATGCTCCCAGAGAGAAAAAGAAGCCATGTAACCAGGAAGCAGCT
CCAGAGCTGCGCCCACGCCTGACCGGGGACTTCCAGGCATCCCCTGGCAGAGAGCCCCGTCCTGGATTCTGTCCCTTTCTCCCCACTTCTTCTGGCTCCTCATTTTTCCTCCTGTTGCACCCCAGCTC
TTTGTCTCCTCCCAGTACGAAAAGGAGAGATGCAAATTTGGAATCTGGTAGGTCGCCCAGACAATGGAGACATCCTCTCCTCTAGCAGGTCAGCGACTGAGAGGGGCCTGACTTCTGCTGGGACAGCT
GGAGAGGAGTCTCATGGGCTGGGATGCTGTTGTGGCTTTGACTTTGGCCAGTGCTTCTGACAGAGGCGGAGCCTGGCAAGTGTACCATCCCACAGGCAGCAGGCACACAGCCCATGGGCTGGATCCTT
CCACACTTTCCTGACAGACCAGAACCAGAGCATCTCGAGGCAACTGTTAGAAATCCAGGGACGAGACAAACAGAGAAGCGCTGGTGAAGCCAACATAGAGACTGTCAATGTGTACACTGGAGTTCCCA
CCCCCACCCCCCACCCGTCACTTAGCCCCTGCCTCCTTCCCCCACTCGTTGTCTTGGCTTGTGCTTTCTCCTCTCCCCATCGGGGATCCGAGACTCTGCCAGGATTCACATGCCACTGAAGCCCACTC
AGTGCCCTCTGGTGACCACACATACCATTCCCCCGGACTCCCACCCAGCAGGCAGCTGTGACCGCAGAAGGGCAGGATGAAGTGGGCCAAGGTTTGGGACAGGTTGACTGTGTAGGTGACAGGGAGGG
AAAGATGATGGCCAGGGGAAAGAGCATCGTATAGGCTAGGGGATTGAACTGTGGACTGATTCAGTGTAAATAAAAACAAATTAACAGGTAGTAGTTCCTGTCAGTTCTGTTGGAAGCAGCCCACTCCC
TCACTTTTACTCCTTCCTCCAACCCTCAATCAGAGCTACTTACAGCCAGGCAGGATGGGGCTTTCCCCAAAGCAATTGGCCGTTTGTCCAGTGGCAGACAATGGTGGCTACAGCCTTTGTGCTTTTAA
GAGTGGGCTGGGATTGTGGAGACTGCCCAGGGGCTTGGCTTTGTCAGAACTTGTACAATCTTCTTTTGATGAAATTATCTGAACTCAACATCTAGCACATAGAATGTGTTCAACAAATGCTTGTTGAA
TGAATAAATTATGACTGCAGACTGGCTCTCCTGCCTTAAACTAATTTCATCCCAGCCTAGTCTCCTGATGTCTGTGCTCGTTATGCTATGCCATGTTGCTTCAGTCAAACAAGAAACACTTACTGAGG
GCATATTGTTTGCCCATCATTGTGCAATATGCTGTGGGACATGGGATGTCGTCTCAGTCTTCAAGGAAATGGAAGGGTTAAGAAATGCATATGAGATTATTACCAATGACACCGTTAATTTATATGAT
GCTTTAAAATTATCAGAGCACTTTCATGTATTTTTCGTGTGACTAGTGAAAAAGACAATGTTGTACAAAATTAAAATATATACAGATGCAATAATGTGAATAGTTAGGATTTATTAAATGCATTATCT
TCAGATCTTTACATGTATAATCTCATTTCTTTCATGCAGTTACTCTGGGATACTGTTCCCATTTGATGGGTAAGAATATTGAAAACCAGAAAAATTAATTATCCCAAGGTTGCATGGCCTTTAGTGGC
ATAGCTAGGATTTGAACCAGGCCTGCCTGACTCCAGAGCTCTGGCTAGTATCTATGCTATACTTAGTTGCCTCTCTGTAAGTATAATATTGGGCAATTATAACCATTTGAGAACAGGACAATATGTAT
TAACCTGAAAAGTGTTCATGATGTCAGTGATAGTACATGGCCTCCTTATGTATTTACTCAAGGGCCCCAAAAGACCAGAGGCCAGAATCCCTAGTAGTCAGAGCAGTGACAGGTCAGAAAAAGGCAGC
TGAGGTCCAATAGTTATGTCTGTGTATTGCTCATTCTACTTACTGATGGAGCCAGCATGTATCTCAACAACTCACCTAGCATTCATCACCCATCCCCAGCATTGGGAAAGGGTCACAATTAAGACCGA
AAGGAAACACAAAGTTAAATATGGGTTAATTATGTAAGCAGATGCCCCACCACGGCAGGATCCAATCACAGCCGAGGGGCCCAGAAGAGAGCAGCGTAAGTTATATTCACATAGTTCCCCAAAGGCTT
TCAACGGGGGCTACAGGAAGGTGCTAGAAATATTGAGGGGCCTGCCATTACTCACCTAGAGCTCACTCTCTGGAGAAGAGGAAAAGGAAGAAGCTATTTCAGCTGCCACATTCTCCCCAATCCCTACT
ATATTATGCTGTCTTTCCTCTTCCTCCTAGCTGGCTTTACATGACCCTAACCCAAAACTACCCTATGGCCCCACACGGGAATGTGTTCAAACGCCCCGACCCCCACCCCCACCCCCATTCCCAAGCCT
CCAACTTAGAACGTTTGTGATTTGGCAGATGGTTTGTTAGGATCTGAAGGATGAAGAGAAGGGTAGAGGTCACCTGGAGAATGAGTTCAAACTGCCAGGGTCTTCCCTTGGTCTTTGTGCGTCAGGAA
GGACTCCGAGTAATTATTCCCTATGCAGAGACAGGAGAGAGGTCTTGTTTACATGAGTGTGCTGGGGCAGGGCTGGACAATCCAGGATATGATTGTAGCCATCCCATGTAGAAAGATCAAAAACCAGA
ACGAAATGAAGACAGCCTCTCAGAACCTCATAGAACAAGCGTCCAGGTCATCTGCTTGTTTGGTGACTTAGATATACAGGCTTACTGGAACTCCATTCACTGTGACCTGAAGTTAAATAATCCCAAAG
AGAAAAAGCTACCTGGGGTATTGGTTGATGTTTGGGGTGATAGGGCTGAATTTTCTGTGCATTTGTCCAACAAAGGCTTTAGAGCACAAAACCAGGTTCATTCTCCCTACCAAATCTTCAGCTTCCTT
CTCCTCATCCCTCCCCAAAACAAGAACTGTGATTTAATTCCGTACGTTGCGGATGTCACTGCTGACCTATGTAGCTGGAGTACTAATCAGGCATCTGACCTGCACTGTCATCCCCTGCCTGGACTTTT
GCGATGGACTCTTTGGGGGAAAAACTAACGCTTTTTAATTATTGTGAAAGCATCATGTGTGTATTGTAGAAGTTTTAGGAAAAAAAGGACAAAATCCAATCCATAAGCTTACCACCCAAGACAAACGT
GTATTCTTTTGAATATACCTTTTAGTTCTTTTTGGTGTAAATGTACACACGCACACACAGTTGTGGATTTTTTTAAACAAAAACTGGATACACTGAATATACTCTTTAATAACTTTTCAAGTGTGTAT
TTATATTTTAGAATATGTAATCCTACACAGATACAAAATTCAAAAAGTACAAACTGCTCTGTAGTCAGAAGTAAATCTTCTCCCTACCCCGTCTGCCAGCATCTAGTTTCCCTCTAATTTATTTTGCA
TCCTAGTGGAGATGCTTACACATTGTCAAACATATGTATATATTCTTTTATCACACACAAATGGCAGCATATTGGACACTTTTTGTTTTTTGCTCCTTCTGTTCCTTCACTTAATAATATCACGAACA
TTTTCGGCATATCAAACTTTCTCAACAGCATCTTCATTGTATGGATGGACCCTTTTTTTATCATCAATCCTCAAATAGTGATTATTTCATTTGTTCCCAATCTTCATTGTAAATAGTGTTGCAACTGA
CATTCTTGTAGCTAAATTTTGCACATGTCTATAACGATTTCCTTAGGATAAACTCCAAGAAGAGACTTGCTTGGCTATTTTTAAGAATTTTGATACATGTTGCCAACCACCCTCCAGAAAGTTTGTAC
CAAAACGCTCTCCTATTTGGATCCTAGAGAGTACCCTGTTTCCTGCACCCTAACACTAGGTATCATCACTTATCAAATCTTTCCCAATTTGGTAGCTGGGATAATAGTATGTCAATGTTATTTTAACT
TTCTTTGATTCTTCGCGAATAACATTTTCATATGCTTATTGACCATTTGTACTTCTTTCTTTGTGAATTTTCTATTTATTTGATATTGGTATGTTTATTATCAATTTGTAATTTTATTAAGAATATTA
TTTTTGTCAAGAAATGCTGCAAATATGCTTTCCAAGTGCTTTGCTTTCAAATTTTGTTTATGGTGCTTTTTGACATACATAAATTCTTAATTCTGCAATTAA

hide sequence


Protein RefSeqs	NP_056166	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH47950	(Get FASTA)	NCBI Sequence Viewer
	BAA13216	(Get FASTA)	NCBI Sequence Viewer
	EAW81043	(Get FASTA)	NCBI Sequence Viewer
	EAW81044	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000256367
	ENSP00000256367.2
GenBank Protein	Q92623	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_056166 ⟸ NM_015351

- UniProtKB:

Q86WT2 (UniProtKB/Swiss-Prot), Q92623 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MERKGSAAGAKGNPSPPAAGEGQRPPPPLCVPGGGGGAPARGQVGAAAEPAELIRRAHEFKSQGAQCYKDKKFREAIGKYHRALLELKGLLPPPGERERDSRPASPAGALKPGRLSEEQSKTVEAIEI
DCYNSLAACLLQAELVNYERVKEYCLKVLKKEGENFKALYRSGVAFYHLGDYDKALYYLKEARTQQPTDTNVIRYIQLTEMKLSRCSQREKEAM

hide sequence

Ensembl Acc Id:

ENSP00000256367 ⟸ ENST00000256367

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q92623-F1-model_v2	AlphaFold	Q92623	1-222	view protein structure

RGD ID:

6791997

Promoter ID:

HG_KWN:19690

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, K562, Lymphoblastoid

Transcripts:

NM_015351, UC001XMH.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	14	70,177,706 - 70,179,317 (-)	MPROMDB

RGD ID:

7228037

Promoter ID:

EPDNEW_H19764

Type:

initiation region

Name:

TTC9_1

Description:

tetratricopeptide repeat domain 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H19765 EPDNEW_H19766

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	70,641,663 - 70,641,723	EPDNEW

RGD ID:

7228039

Promoter ID:

EPDNEW_H19765

Type:

initiation region

Name:

TTC9_2

Description:

tetratricopeptide repeat domain 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H19764 EPDNEW_H19766

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	70,641,788 - 70,641,848	EPDNEW

RGD ID:

7228041

Promoter ID:

EPDNEW_H19766

Type:

initiation region

Name:

TTC9_3

Description:

tetratricopeptide repeat domain 9

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H19764 EPDNEW_H19765

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	14	70,641,916 - 70,641,976	EPDNEW

Database	Acc Id	Source(s)
COSMIC	TTC9	COSMIC
Ensembl Genes	ENSG00000133985	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000256367	ENTREZGENE
	ENST00000256367.3	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000133985	GTEx
HGNC ID	HGNC:20267	ENTREZGENE
Human Proteome Map	TTC9	Human Proteome Map
InterPro	Immunophilin_FKBP-type	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
	TPR_2	UniProtKB/Swiss-Prot
	TPR_repeat	UniProtKB/Swiss-Prot
KEGG Report	hsa:23508	UniProtKB/Swiss-Prot
NCBI Gene	23508	ENTREZGENE
OMIM	610488	OMIM
PANTHER	PEPTIDYLPROLYL ISOMERASE	UniProtKB/Swiss-Prot
	TETRATRICOPEPTIDE REPEAT DOMAIN 9	UniProtKB/Swiss-Prot
Pfam	TPR_2	UniProtKB/Swiss-Prot
PharmGKB	PA134905515	PharmGKB
PROSITE	TPR	UniProtKB/Swiss-Prot
	TPR_REGION	UniProtKB/Swiss-Prot
SMART	TPR	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48452	UniProtKB/Swiss-Prot
UniProt	Q86WT2	ENTREZGENE
	Q92623	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q86WT2	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Manual Human Phenotype Annotations - RGD

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Imported Disease Annotations - CTD

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