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Gene: CD5L (CD5 molecule like) Homo sapiens

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Symbol:

CD5L

Name:

CD5 molecule like

RGD ID:

1318347

HGNC Page

HGNC:1690

Description:

Predicted to be involved in cellular defense response. Predicted to act upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AIM; API6; apoptosis inhibitor 6; apoptosis inhibitor expressed by macrophages; apoptosis inhibitor of macrophage; CD5 antigen-like; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule-like; CT-2; hAIM; igM-associated peptide; PRO229; SP-ALPHA; Spalpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Cd5l (CD5 antigen-like)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Cd5l (Cd5 molecule-like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Cd5l (CD5 molecule like)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	CD5L (CD5 molecule like)	NCBI	Ortholog
Canis lupus familiaris (dog):	CD5L (CD5 molecule like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Sus scrofa (pig):	CD5L (CD5 molecule like)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	CD5L (CD5 molecule like)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Cd5l (CD5 molecule like)	NCBI	Ortholog
Other homologs ²
Rattus norvegicus (Norway rat):	Fcrl1 (Fc receptor-like 1)	HGNC	EggNOG, Ensembl, Inparanoid, PhylomeDB, Treefam
Mus musculus (house mouse):	Cd5 (CD5 antigen)	HGNC	Treefam
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Cd5l (Cd5 molecule-like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cd5l (CD5 antigen-like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	157,827,068 - 157,841,808 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	157,830,911 - 157,898,256 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	157,796,858 - 157,811,598 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	156,067,330 - 156,078,175 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	154,613,776 - 154,624,624	NCBI
Celera	1	130,871,890 - 130,882,819 (-)	NCBI		Celera
Cytogenetic Map	1	q23.1	NCBI
HuRef	1	129,158,567 - 129,169,496 (-)	NCBI		HuRef
CHM1_1	1	159,196,948 - 159,207,869 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	156,964,145 - 156,978,876 (-)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	gastrointestinal stromal tumor		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Gastrointestinal stromal tumor	ClinVar	PMID:28492532
CD5L	Human	parathyroid carcinoma		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Parathyroid carcinoma	ClinVar	PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	Experimental Liver Cirrhosis		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:25380136
CD5L	Human	hepatocellular carcinoma		EXP		11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28284560

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	1-chloro-2,4-dinitrobenzene	affects expression	ISO	Cd5l (Mus musculus)	6480464	Dinitrochlorobenzene affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	1-naphthyl isothiocyanate	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	1-Naphthylisothiocyanate results in increased expression of CD5L mRNA	CTD	PMID:25380136
CD5L	Human	17alpha-ethynylestradiol	affects expression	ISO	Cd5l (Mus musculus)	6480464	Ethinyl Estradiol affects the expression of CD5L mRNA	CTD	PMID:17555576
CD5L	Human	17alpha-ethynylestradiol	increases expression	ISO	Cd5l (Mus musculus)	6480464	Ethinyl Estradiol results in increased expression of CD5L mRNA	CTD	PMID:12072388
CD5L	Human	17beta-estradiol	increases expression	ISO	Cd5l (Mus musculus)	6480464	Estradiol results in increased expression of CD5L mRNA	CTD	PMID:19484750
CD5L	Human	17beta-estradiol	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Estradiol results in decreased expression of CD5L mRNA	CTD	PMID:39298647
CD5L	Human	17beta-estradiol	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CD5L mRNA	CTD	PMID:32741896
CD5L	Human	17beta-estradiol	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Estradiol results in increased expression of CD5L mRNA	CTD	PMID:32145629
CD5L	Human	17beta-estradiol 3-benzoate	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CD5L mRNA	CTD	PMID:32741896
CD5L	Human	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in decreased expression of CD5L mRNA	CTD	PMID:15652763
CD5L	Human	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Cd5l (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of CD5L mRNA	CTD	PMID:28922406
CD5L	Human	2,4-dibromophenyl 2,4,5-tribromophenyl ether	affects expression	ISO	Cd5l (Mus musculus)	6480464	2 more ...	CTD	PMID:38648751
CD5L	Human	2-tert-butylhydroquinone	increases expression	ISO	Cd5l (Mus musculus)	6480464	2-tert-butylhydroquinone results in increased expression of CD5L mRNA	CTD	PMID:16014739
CD5L	Human	4,4'-diaminodiphenylmethane	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	4 and 4'-diaminodiphenylmethane results in increased expression of CD5L mRNA	CTD	PMID:25380136 and PMID:30723492
CD5L	Human	4,4'-sulfonyldiphenol	decreases expression	ISO	Cd5l (Mus musculus)	6480464	bisphenol S results in decreased expression of CD5L mRNA	CTD	PMID:39298647
CD5L	Human	6-propyl-2-thiouracil	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Propylthiouracil results in increased expression of CD5L mRNA	CTD	PMID:24780913
CD5L	Human	aflatoxin B1	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Aflatoxin B1 results in decreased expression of CD5L mRNA	CTD	PMID:19770486
CD5L	Human	aflatoxin B1	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Aflatoxin B1 results in decreased expression of CD5L mRNA	CTD	PMID:25378103 and PMID:33354967
CD5L	Human	aflatoxin B1	decreases methylation	EXP		6480464	Aflatoxin B1 results in decreased methylation of CD5L gene	CTD	PMID:27153756
CD5L	Human	alpha-hexylcinnamaldehyde	affects expression	ISO	Cd5l (Mus musculus)	6480464	hexyl cinnamic aldehyde affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	arsenite(3-)	decreases expression	ISO	Cd5l (Mus musculus)	6480464	arsenite results in decreased expression of CD5L protein	CTD	PMID:37955338
CD5L	Human	arsenous acid	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Arsenic Trioxide results in decreased expression of CD5L mRNA	CTD	PMID:35676786
CD5L	Human	benzo[a]pyrene	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Benzo(a)pyrene results in decreased expression of CD5L mRNA	CTD	PMID:19770486
CD5L	Human	benzo[a]pyrene	affects methylation	EXP		6480464	Benzo(a)pyrene affects the methylation of CD5L promoter	CTD	PMID:27901495
CD5L	Human	benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of CD5L mRNA	CTD	PMID:22316170
CD5L	Human	bexarotene	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[bexarotene co-treated with Tamoxifen] results in decreased expression of CD5L mRNA	CTD	PMID:17630414
CD5L	Human	bis(2-ethylhexyl) phthalate	increases expression	ISO	Cd5l (Mus musculus)	6480464	Diethylhexyl Phthalate results in increased expression of CD5L mRNA	CTD	PMID:34319233
CD5L	Human	bisphenol A	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	bisphenol A results in decreased expression of CD5L mRNA	CTD	PMID:25181051 and PMID:34947998
CD5L	Human	bisphenol A	increases expression	ISO	Cd5l (Mus musculus)	6480464	bisphenol A results in increased expression of CD5L mRNA	CTD	PMID:32156529
CD5L	Human	bisphenol A	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	bisphenol A results in increased expression of CD5L mRNA	CTD	PMID:32145629
CD5L	Human	bisphenol F	increases expression	ISO	Cd5l (Mus musculus)	6480464	bisphenol F results in increased expression of CD5L mRNA	CTD	PMID:38685157
CD5L	Human	buspirone	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Buspirone results in decreased expression of CD5L mRNA	CTD	PMID:24136188
CD5L	Human	cadmium atom	multiple interactions	EXP		6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CD5L mRNA	CTD	PMID:35301059
CD5L	Human	cadmium dichloride	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Cadmium Chloride results in decreased expression of CD5L mRNA	CTD	PMID:25993096
CD5L	Human	cadmium dichloride	multiple interactions	EXP		6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CD5L mRNA	CTD	PMID:35301059
CD5L	Human	CGP 52608	multiple interactions	EXP		6480464	CGP 52608 promotes the reaction [RORA protein binds to CD5L gene]	CTD	PMID:28238834
CD5L	Human	chlordecone	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Chlordecone results in decreased expression of CD5L mRNA	CTD	PMID:29980752
CD5L	Human	chlorpyrifos	increases expression	ISO	Cd5l (Mus musculus)	6480464	Chlorpyrifos results in increased expression of CD5L mRNA	CTD	PMID:34289071 and PMID:37019170
CD5L	Human	choline	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[Dietary Fats co-treated with Choline deficiency] results in increased expression of CD5L mRNA and PANX1 gene mutant form inhibits the reaction [[Dietary Fats co-treated with Choline deficiency] results in increased expression of CD5L mRNA]	CTD	PMID:29246445
CD5L	Human	cisplatin	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Cisplatin results in decreased expression of CD5L mRNA	CTD	PMID:22023808
CD5L	Human	clofibrate	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of CD5L mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CD5L mRNA]	CTD	PMID:17585979
CD5L	Human	decabromodiphenyl ether	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	decabromobiphenyl ether results in increased expression of CD5L mRNA	CTD	PMID:23640034
CD5L	Human	diarsenic trioxide	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Arsenic Trioxide results in decreased expression of CD5L mRNA	CTD	PMID:35676786
CD5L	Human	diclofenac	increases expression	ISO	Cd5l (Mus musculus)	6480464	Diclofenac results in increased expression of CD5L mRNA	CTD	PMID:26934552
CD5L	Human	diquat	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Diquat results in decreased expression of CD5L protein	CTD	PMID:36851058
CD5L	Human	doramapimod	decreases expression	ISO	Cd5l (Mus musculus)	6480464	doramapimod results in decreased expression of CD5L mRNA	CTD	PMID:21328587
CD5L	Human	flutamide	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Flutamide results in decreased expression of CD5L mRNA	CTD	PMID:24136188
CD5L	Human	folic acid	decreases expression	EXP		6480464	Folic Acid results in decreased expression of CD5L mRNA	CTD	PMID:21867686
CD5L	Human	fumonisin B1	increases expression	ISO	Cd5l (Mus musculus)	6480464	fumonisin B1 results in increased expression of CD5L mRNA	CTD	PMID:16221962
CD5L	Human	genistein	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Genistein results in decreased expression of CD5L mRNA	CTD	PMID:32186404
CD5L	Human	glycidol	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	glycidol results in increased expression of CD5L mRNA	CTD	PMID:24395379
CD5L	Human	lipopolysaccharide	increases expression	ISO	Cd5l (Mus musculus)	6480464	Lipopolysaccharides results in increased expression of CD5L mRNA	CTD	PMID:27339419
CD5L	Human	lipopolysaccharide	multiple interactions	EXP		6480464	[S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CD5L mRNA	CTD	PMID:35811015
CD5L	Human	methyl salicylate	affects expression	ISO	Cd5l (Mus musculus)	6480464	methyl salicylate affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	N-nitrosodimethylamine	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Dimethylnitrosamine results in increased expression of CD5L mRNA	CTD	PMID:25380136
CD5L	Human	nefazodone	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	nefazodone results in decreased expression of CD5L mRNA	CTD	PMID:24136188
CD5L	Human	nimesulide	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	nimesulide results in decreased expression of CD5L mRNA	CTD	PMID:24136188
CD5L	Human	nonanoic acid	affects expression	ISO	Cd5l (Mus musculus)	6480464	pelargonic acid affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	oxaliplatin	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	oxaliplatin results in increased expression of CD5L mRNA	CTD	PMID:25729387
CD5L	Human	oxaliplatin	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of CD5L mRNA	CTD	PMID:25729387
CD5L	Human	oxycodone	decreases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Oxycodone results in decreased expression of CD5L mRNA	CTD	PMID:23439660
CD5L	Human	paracetamol	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of CD5L mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CD5L mRNA]	CTD	PMID:17585979
CD5L	Human	paracetamol	affects expression	ISO	Cd5l (Mus musculus)	6480464	Acetaminophen affects the expression of CD5L mRNA	CTD	PMID:17562736
CD5L	Human	pentachlorophenol	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Pentachlorophenol results in decreased expression of CD5L mRNA	CTD	PMID:23892564
CD5L	Human	phenformin	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Phenformin results in increased expression of CD5L mRNA	CTD	PMID:31324951
CD5L	Human	phenobarbital	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CD5L mRNA]	CTD	PMID:19482888
CD5L	Human	phenobarbital	decreases expression	ISO	Cd5l (Mus musculus)	6480464	Phenobarbital results in decreased expression of CD5L mRNA	CTD	PMID:19482888
CD5L	Human	phthalaldehyde	affects expression	ISO	Cd5l (Mus musculus)	6480464	o-Phthalaldehyde affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	pirinixic acid	decreases expression	ISO	Cd5l (Mus musculus)	6480464	pirinixic acid results in decreased expression of CD5L mRNA	CTD	PMID:11798191 more ...
CD5L	Human	resveratrol	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA	CTD	PMID:25905778
CD5L	Human	rotenone	affects expression	ISO	Cd5l (Rattus norvegicus)	6480464	Rotenone affects the expression of CD5L mRNA	CTD	PMID:28374803
CD5L	Human	S-(1,2-dichlorovinyl)-L-cysteine	multiple interactions	EXP		6480464	[S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of CD5L mRNA	CTD	PMID:35811015
CD5L	Human	sodium arsenite	increases expression	ISO	Cd5l (Mus musculus)	6480464	sodium arsenite results in increased expression of CD5L mRNA	CTD	PMID:16014739
CD5L	Human	sodium arsenite	decreases expression	ISO	Cd5l (Mus musculus)	6480464	sodium arsenite results in decreased expression of CD5L mRNA	CTD	PMID:37682722
CD5L	Human	streptozocin	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA	CTD	PMID:25905778
CD5L	Human	succimer	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[Succimer binds to Magnetite Nanoparticles] which results in increased expression of CD5L mRNA	CTD	PMID:21641980
CD5L	Human	tamoxifen	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[bexarotene co-treated with Tamoxifen] results in decreased expression of CD5L mRNA	CTD	PMID:17630414
CD5L	Human	testosterone	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CD5L mRNA	CTD	PMID:32741896
CD5L	Human	tetrachloromethane	increases expression	ISO	Cd5l (Mus musculus)	6480464	Carbon Tetrachloride results in increased expression of CD5L mRNA	CTD	PMID:27339419
CD5L	Human	tetrachloromethane	affects expression	ISO	Cd5l (Mus musculus)	6480464	Carbon Tetrachloride affects the expression of CD5L mRNA	CTD	PMID:31919559
CD5L	Human	tetrachloromethane	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[PANX1 protein co-treated with Carbon Tetrachloride] affects the expression of CD5L mRNA	CTD	PMID:29987408
CD5L	Human	thioacetamide	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Thioacetamide results in increased expression of CD5L mRNA	CTD	PMID:34492290
CD5L	Human	titanium dioxide	increases expression	ISO	Cd5l (Mus musculus)	6480464	titanium dioxide results in increased expression of CD5L mRNA	CTD	PMID:23557971
CD5L	Human	topotecan	multiple interactions	ISO	Cd5l (Rattus norvegicus)	6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of CD5L mRNA	CTD	PMID:25729387
CD5L	Human	topotecan	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	Topotecan results in increased expression of CD5L mRNA	CTD	PMID:25729387
CD5L	Human	trimellitic anhydride	increases expression	ISO	Cd5l (Mus musculus)	6480464	trimellitic anhydride results in increased expression of CD5L mRNA	CTD	PMID:19042947
CD5L	Human	trimellitic anhydride	affects expression	ISO	Cd5l (Mus musculus)	6480464	trimellitic anhydride affects the expression of CD5L mRNA	CTD	PMID:22302311
CD5L	Human	triphenyl phosphate	affects expression	ISO	Cd5l (Rattus norvegicus)	6480464	triphenyl phosphate affects the expression of CD5L mRNA	CTD	PMID:30589522
CD5L	Human	troglitazone	decreases expression	ISO	Cd5l (Mus musculus)	6480464	troglitazone results in decreased expression of CD5L mRNA	CTD	PMID:17569031
CD5L	Human	vinclozolin	increases expression	ISO	Cd5l (Rattus norvegicus)	6480464	vinclozolin results in increased expression of CD5L mRNA	CTD	PMID:23034163
CD5L	Human	XL147	multiple interactions	ISO	Cd5l (Mus musculus)	6480464	[N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of CD5L mRNA	CTD	PMID:27935865

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	apoptotic process	involved_in	IEA	UniProtKB-KW:KW-0053	150520179		UniProt	GO_REF:0000043
CD5L	Human	cellular defense response	involved_in	TAS		150520179	PMID:9045627	PINC	PMID:9045627
CD5L	Human	immune system process	involved_in	IEA	UniProtKB-KW:KW-0391	150520179		UniProt	GO_REF:0000043
CD5L	Human	inflammatory response	involved_in	IEA	UniProtKB-KW:KW-0395	150520179		UniProt	GO_REF:0000043
CD5L	Human	positive regulation of complement-dependent cytotoxicity	acts_upstream_of_or_within	IEA	UniProtKB:Q9QWK4 and ensembl:ENSMUSP00000015998	150520179		Ensembl	GO_REF:0000107
CD5L	Human	regulation of complement activation	acts_upstream_of_or_within	IEA	UniProtKB:Q9QWK4 and ensembl:ENSMUSP00000015998	150520179		Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	blood microparticle	located_in	HDA		150520179	PMID:22516433	UniProt	PMID:22516433
CD5L	Human	cell surface	located_in	IDA		150520179	PMID:25284781	MGI	PMID:25284781
CD5L	Human	cell surface	located_in	IEA	UniProtKB:Q9QWK4 and ensembl:ENSMUSP00000015998	150520179		Ensembl	GO_REF:0000107
CD5L	Human	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
CD5L	Human	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
CD5L	Human	extracellular region	located_in	IEA	UniProtKB-SubCell:SL-0243	150520179		UniProt	GO_REF:0000044
CD5L	Human	extracellular region	located_in	NAS		150520179	PMID:14718574	UniProt	PMID:14718574
CD5L	Human	extracellular region	located_in	IEA	UniProtKB-KW:KW-0964	150520179		UniProt	GO_REF:0000043
CD5L	Human	extracellular space	located_in	TAS		150520179	PMID:9045627	PINC	PMID:9045627
CD5L	Human	membrane	located_in	IEA	InterPro:IPR001190 and InterPro:IPR036772	150520179		InterPro	GO_REF:0000002
CD5L	Human	plasma membrane	located_in	IEA	UniProtKB:Q9QWK4 and ensembl:ENSMUSP00000015998	150520179		Ensembl	GO_REF:0000107
CD5L	Human	plasma membrane	is_active_in	IBA	MGI:1334419 and PANTHER:PTN002499858	150520179		GO_Central	GO_REF:0000033

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
CD5L	Human	Gastrointestinal stroma tumor		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Gastrointestinal stromal tumor	ClinVar	PMID:28492532
CD5L	Human	Parathyroid carcinoma		IAGP	(Homo sapiens)	8554872	ClinVar Annotator: match by term: Parathyroid carcinoma	ClinVar	PMID:28492532

#	Reference Title	Reference Citation
1.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:8034987	PMID:9045627	PMID:11981870	PMID:12477932	PMID:12975309	PMID:14718574	PMID:15340161	PMID:15489334	PMID:16030018	PMID:16344560	PMID:16710414	PMID:18051367
PMID:18660489	PMID:19116453	PMID:19155514	PMID:19204726	PMID:20237496	PMID:20379614	PMID:21873635	PMID:21970839	PMID:22516433	PMID:23236605	PMID:23376485	PMID:24223991
PMID:24295828	PMID:25284781	PMID:25302503	PMID:25713983	PMID:26048980	PMID:26135353	PMID:26726878	PMID:28743989	PMID:29465313	PMID:29593730	PMID:30173083	PMID:30959370
PMID:31076347	PMID:32611589	PMID:34194427	PMID:34629330	PMID:35249136	PMID:35330909	PMID:36427004	PMID:37087580	PMID:37191481	PMID:37592330	PMID:38006711

CD5L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	157,827,068 - 157,841,808 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	157,830,911 - 157,898,256 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	157,796,858 - 157,811,598 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	156,067,330 - 156,078,175 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	154,613,776 - 154,624,624	NCBI
Celera	1	130,871,890 - 130,882,819 (-)	NCBI		Celera
Cytogenetic Map	1	q23.1	NCBI
HuRef	1	129,158,567 - 129,169,496 (-)	NCBI		HuRef
CHM1_1	1	159,196,948 - 159,207,869 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	156,964,145 - 156,978,876 (-)	NCBI		T2T-CHM13v2.0

Cd5l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	87,265,188 - 87,278,381 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	87,265,188 - 87,278,380 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	87,357,881 - 87,371,074 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	87,357,881 - 87,371,073 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	87,161,803 - 87,174,996 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	87,443,902 - 87,457,000 (+)	NCBI		MGSCv36	mm8
Celera	3	87,393,446 - 87,406,451 (+)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	38.19	NCBI

Cd5l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	175,088,915 - 175,099,928 (+)	NCBI		GRCr8
mRatBN7.2	2	172,791,007 - 172,802,018 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	172,790,934 - 172,829,753 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	179,941,082 - 179,952,158 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	177,963,407 - 177,974,487 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	172,552,657 - 172,563,725 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	186,685,104 - 186,696,117 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	186,685,104 - 186,696,117 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	206,092,828 - 206,129,923 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	179,383,719 - 179,394,732 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	179,333,824 - 179,344,769 (+)	NCBI
Celera	2	166,744,714 - 166,755,732 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Cd5l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	9,667,514 - 9,689,150 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	9,670,958 - 9,690,331 (-)	NCBI	ChiLan1.0	ChiLan1.0

CD5L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	92,003,400 - 92,013,965 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	91,747,359 - 91,757,924 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	133,192,387 - 133,203,293 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	136,981,543 - 136,996,263 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	136,985,701 - 136,996,263 (-)	Ensembl	panpan1.1		panPan2

CD5L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	40,516,190 - 40,526,528 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	40,516,190 - 40,526,528 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	39,997,882 - 40,008,220 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	40,348,184 - 40,358,523 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	40,348,133 - 40,372,831 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	40,190,415 - 40,200,749 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	40,198,604 - 40,208,942 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	40,467,651 - 40,477,985 (+)	NCBI		UU_Cfam_GSD_1.0

CD5L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	4	92,394,535 - 92,412,146 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	100,732,584 - 100,750,194 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD5L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	6,059,103 - 6,074,657 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	6,065,620 - 6,070,904 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	5,293,198 - 5,303,594 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cd5l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	3,060,365 - 3,072,801 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	3,060,436 - 3,071,570 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in CD5L
31 total Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]\|See cases [RCV000052483]	Chr17:36449220..83086677 [GRCh38] Chr17:58617905..81044553 [GRCh37] Chr17:55972687..78637842 [NCBI36] Chr17:17q23.2-25.3	pathogenic
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3	copy number gain	See cases [RCV000050957]	Chr17:36449220..68170214 [GRCh38] Chr17:48563237..65936105 [GRCh37] Chr17:45918236..63677950 [NCBI36] Chr17:17q21.33-24.2	pathogenic
GRCh38/hg38 17q22(chr17:56958745-58171125)x1	copy number loss	See cases [RCV000053434]	Chr17:56958745..58171125 [GRCh38] Chr17:55036106..56248486 [GRCh37] Chr17:52391105..53603485 [NCBI36] Chr17:17q22	pathogenic
GRCh38/hg38 17q22(chr17:56683505-58084939)x1	copy number loss	See cases [RCV000135409]	Chr17:56683505..58084939 [GRCh38] Chr17:54760866..56162300 [GRCh37] Chr17:52115865..53517299 [NCBI36] Chr17:17q22	pathogenic
NM_021626.2(SCPEP1):c.450C>T (p.Phe150=)	single nucleotide variant	Malignant melanoma [RCV000063259]	Chr17:56987829 [GRCh38] Chr17:55065190 [GRCh37] Chr17:52420189 [NCBI36] Chr17:17q22	not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3	copy number gain	See cases [RCV000137437]	Chr17:36449220..75053130 [GRCh38] Chr17:57595736..73049225 [GRCh37] Chr17:54950518..70560820 [NCBI36] Chr17:17q23.1-25.1	pathogenic
GRCh37/hg19 17q21.33-23.2(chr17:49076980-58740945)x3	copy number gain	See cases [RCV000448805]	Chr17:49076980..58740945 [GRCh37] Chr17:17q21.33-23.2	pathogenic
GRCh37/hg19 17q22(chr17:52189051-57477162)x3	copy number gain	See cases [RCV000448801]	Chr17:52189051..57477162 [GRCh37] Chr17:17q22	pathogenic
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3	copy number gain	See cases [RCV000447823]	Chr17:42580684..81085615 [GRCh37] Chr17:17q21.31-25.3	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)	copy number gain	See cases [RCV000511439]	Chr17:526..81041938 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
NM_021626.3(SCPEP1):c.557G>A (p.Arg186Gln)	single nucleotide variant	not specified [RCV004295762]	Chr17:56991109 [GRCh38] Chr17:55068470 [GRCh37] Chr17:17q22	likely benign
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3	copy number gain	See cases [RCV000512441]	Chr17:526..81041938 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3	copy number gain	not provided [RCV000739320]	Chr17:7214..81058310 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3	copy number gain	not provided [RCV000739324]	Chr17:8547..81060040 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
NC_000017.10:g.(?_54671585)_(59938900_?)dup	duplication	Familial aplasia of the vermis [RCV001923071]	Chr17:54671585..59938900 [GRCh37] Chr17:17q22-23.2	uncertain significance
GRCh37/hg19 17q22(chr17:55043662-56728123)x1	copy number loss	See cases [RCV002292214]	Chr17:55043662..56728123 [GRCh37] Chr17:17q22	pathogenic
NM_021626.3(SCPEP1):c.1151G>A (p.Arg384Gln)	single nucleotide variant	not specified [RCV004331912]	Chr17:57002036 [GRCh38] Chr17:55079397 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.323C>A (p.Ala108Asp)	single nucleotide variant	not specified [RCV004324013]	Chr17:56987702 [GRCh38] Chr17:55065063 [GRCh37] Chr17:17q22	uncertain significance
GRCh37/hg19 17q22(chr17:54584318-55220914)x1	copy number loss	not provided [RCV000683944]	Chr17:54584318..55220914 [GRCh37] Chr17:17q22	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3	copy number gain	not provided [RCV000739325]	Chr17:12344..81057996 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
NM_021626.3(SCPEP1):c.850T>G (p.Ser284Ala)	single nucleotide variant	not specified [RCV004235715]	Chr17:56997025 [GRCh38] Chr17:55074386 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1294A>G (p.Met432Val)	single nucleotide variant	not specified [RCV004161970]	Chr17:57002179 [GRCh38] Chr17:55079540 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.545A>T (p.Lys182Met)	single nucleotide variant	not specified [RCV004184215]	Chr17:56988289 [GRCh38] Chr17:55065650 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1120G>A (p.Val374Ile)	single nucleotide variant	not specified [RCV004204645]	Chr17:57000980 [GRCh38] Chr17:55078341 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.581C>T (p.Ala194Val)	single nucleotide variant	not specified [RCV004232977]	Chr17:56991133 [GRCh38] Chr17:55068494 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.86T>C (p.Ile29Thr)	single nucleotide variant	not specified [RCV004159784]	Chr17:56981091 [GRCh38] Chr17:55058452 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1049T>C (p.Ile350Thr)	single nucleotide variant	not specified [RCV004193704]	Chr17:57000909 [GRCh38] Chr17:55078270 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1063G>A (p.Glu355Lys)	single nucleotide variant	not specified [RCV004078084]	Chr17:57000923 [GRCh38] Chr17:55078284 [GRCh37] Chr17:17q22	likely benign
NM_021626.3(SCPEP1):c.1342G>A (p.Val448Met)	single nucleotide variant	not specified [RCV004206330]	Chr17:57006218 [GRCh38] Chr17:55083579 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1117A>T (p.Ile373Phe)	single nucleotide variant	not specified [RCV004206939]	Chr17:57000977 [GRCh38] Chr17:55078338 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.896G>A (p.Arg299His)	single nucleotide variant	not specified [RCV004197816]	Chr17:56998400 [GRCh38] Chr17:55075761 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.310A>G (p.Thr104Ala)	single nucleotide variant	not specified [RCV004221264]	Chr17:56985462 [GRCh38] Chr17:55062823 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.311C>G (p.Thr104Ser)	single nucleotide variant	not specified [RCV004341321]	Chr17:56985463 [GRCh38] Chr17:55062824 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.602C>A (p.Ser201Tyr)	single nucleotide variant	not specified [RCV004658841]	Chr17:56991154 [GRCh38] Chr17:55068515 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.398A>G (p.Lys133Arg)	single nucleotide variant	not specified [RCV004674627]	Chr17:56987777 [GRCh38] Chr17:55065138 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1091C>T (p.Thr364Met)	single nucleotide variant	not specified [RCV004674628]	Chr17:57000951 [GRCh38] Chr17:55078312 [GRCh37] Chr17:17q22	uncertain significance
Single allele	deletion	Breast-ovarian cancer, familial, susceptibility to, 1 [RCV004759420]	Chr17:41231503..41277589 [GRCh37] Chr17:17q21.31-22	pathogenic
NM_021626.3(SCPEP1):c.1157T>C (p.Leu386Pro)	single nucleotide variant	not specified [RCV004859028]	Chr17:57002042 [GRCh38] Chr17:55079403 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1007A>G (p.Asn336Ser)	single nucleotide variant	not specified [RCV004859030]	Chr17:57000867 [GRCh38] Chr17:55078228 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.16C>T (p.Arg6Trp)	single nucleotide variant	not specified [RCV004859029]	Chr17:56978175 [GRCh38] Chr17:55055536 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1351C>A (p.Gln451Lys)	single nucleotide variant	not specified [RCV004356187]	Chr17:57006227 [GRCh38] Chr17:55083588 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1172T>G (p.Leu391Arg)	single nucleotide variant	not specified [RCV004340007]	Chr17:57002057 [GRCh38] Chr17:55079418 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.100G>C (p.Glu34Gln)	single nucleotide variant	not specified [RCV004455018]	Chr17:56981105 [GRCh38] Chr17:55058466 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1208A>G (p.Tyr403Cys)	single nucleotide variant	not specified [RCV004455020]	Chr17:57002093 [GRCh38] Chr17:55079454 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.411G>A (p.Met137Ile)	single nucleotide variant	not specified [RCV004455024]	Chr17:56987790 [GRCh38] Chr17:55065151 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.413T>A (p.Val138Glu)	single nucleotide variant	not specified [RCV004455025]	Chr17:56987792 [GRCh38] Chr17:55065153 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.755T>A (p.Leu252Gln)	single nucleotide variant	not specified [RCV004455028]	Chr17:56995604 [GRCh38] Chr17:55072965 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.779T>C (p.Ile260Thr)	single nucleotide variant	not specified [RCV004455029]	Chr17:56995628 [GRCh38] Chr17:55072989 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.917G>A (p.Arg306Gln)	single nucleotide variant	not specified [RCV004455030]	Chr17:56998421 [GRCh38] Chr17:55075782 [GRCh37] Chr17:17q22	likely benign
NM_021626.3(SCPEP1):c.233C>T (p.Pro78Leu)	single nucleotide variant	not specified [RCV004455021]	Chr17:56985385 [GRCh38] Chr17:55062746 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1087G>A (p.Val363Met)	single nucleotide variant	not specified [RCV004455019]	Chr17:57000947 [GRCh38] Chr17:55078308 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.304A>G (p.Lys102Glu)	single nucleotide variant	not specified [RCV004455023]	Chr17:56985456 [GRCh38] Chr17:55062817 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.610T>C (p.Ser204Pro)	single nucleotide variant	not specified [RCV004455026]	Chr17:56991162 [GRCh38] Chr17:55068523 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.302G>A (p.Arg101Gln)	single nucleotide variant	not specified [RCV004455022]	Chr17:56985454 [GRCh38] Chr17:55062815 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.667G>A (p.Glu223Lys)	single nucleotide variant	not specified [RCV004455027]	Chr17:56995516 [GRCh38] Chr17:55072877 [GRCh37] Chr17:17q22	uncertain significance
NC_000017.10:g.(?_54671585)_(55927371_?)del	deletion	not provided [RCV004581399]	Chr17:54671585..55927371 [GRCh37] Chr17:17q22	pathogenic
GRCh37/hg19 17q12-22(chr17:41196270-41277589)	copy number loss	Breast-ovarian cancer, familial, susceptibility to, 1 [RCV004759419]	Chr17:41196270..41277589 [GRCh37] Chr17:17q12-22	pathogenic
NM_021626.3(SCPEP1):c.189G>T (p.Lys63Asn)	single nucleotide variant	not specified [RCV004859026]	Chr17:56981194 [GRCh38] Chr17:55058555 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.959A>T (p.Lys320Met)	single nucleotide variant	not specified [RCV004859027]	Chr17:56998463 [GRCh38] Chr17:55075824 [GRCh37] Chr17:17q22	uncertain significance
NM_021626.3(SCPEP1):c.1026G>C (p.Glu342Asp)	single nucleotide variant	not specified [RCV004859031]	Chr17:57000886 [GRCh38] Chr17:55078247 [GRCh37] Chr17:17q22	uncertain significance

Predicted Target Of

	Summary Value
Count of predictions:	572
Count of miRNA genes:	465
Interacting mature miRNAs:	494
Transcripts:	ENST00000368174, ENST00000484609
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
597227421	GWAS1323495_H	eye colour measurement QTL GWAS1323495 (human)		0.000004	eye colour measurement	eye morphological measurement (CMO:0003080)	1	157828210	157828211	Human
597428761	GWAS1524835_H	protein measurement QTL GWAS1524835 (human)		2e-37	protein measurement		1	157834858	157834859	Human
597141201	GWAS1237275_H	CD5 antigen-like measurement QTL GWAS1237275 (human)		2e-08	CD5 antigen-like measurement		1	157834858	157834859	Human
597341149	GWAS1437223_H	color vision disorder QTL GWAS1437223 (human)		0.000003	color vision disorder		1	157834470	157834471	Human
597123632	GWAS1219706_H	blood protein measurement QTL GWAS1219706 (human)		2e-24	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	1	157834858	157834859	Human
597175216	GWAS1271290_H	CD5 antigen-like measurement QTL GWAS1271290 (human)		3e-45	CD5 antigen-like measurement		1	157841795	157841796	Human
597175217	GWAS1271291_H	CD5 antigen-like measurement QTL GWAS1271291 (human)		2e-166	CD5 antigen-like measurement		1	157834858	157834859	Human
597027704	GWAS1123778_H	blood protein measurement QTL GWAS1123778 (human)		2e-82	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	1	157829133	157829134	Human
1357381	BW57_H	Body weight QTL 57 (human)	1	0.0001	Body weight	fat free mass after exercise training	1	140630236	166630236	Human
597271528	GWAS1367602_H	CD5 antigen-like measurement QTL GWAS1367602 (human)		1e-12	CD5 antigen-like measurement		1	157829133	157829134	Human
597026976	GWAS1123050_H	blood protein measurement QTL GWAS1123050 (human)		3e-55	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	1	157829133	157829134	Human
597271308	GWAS1367382_H	Fc receptor-like protein 3 measurement QTL GWAS1367382 (human)		4e-11	Fc receptor-like protein 3 measurement		1	157831788	157831789	Human
407378416	GWAS1027392_H	blood protein measurement QTL GWAS1027392 (human)		2e-12	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	1	157829133	157829134	Human
597027496	GWAS1123570_H	blood protein measurement QTL GWAS1123570 (human)		7e-16	blood protein amount (VT:0005416)	blood protein measurement (CMO:0000028)	1	157829133	157829134	Human
597159848	GWAS1255922_H	leucine measurement QTL GWAS1255922 (human)		0.000006	leucine measurement	blood amino acid measurement (CMO:0003730)	1	157833087	157833088	Human

D1S3558

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	157,801,073 - 157,801,218	UniSTS	GRCh37
Build 36	1	156,067,697 - 156,067,842	RGD	NCBI36
Celera	1	130,872,259 - 130,872,404	RGD
Cytogenetic Map	1	q21-q23	UniSTS
HuRef	1	129,158,936 - 129,159,081	UniSTS

D1S176

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	157,797,028 - 157,797,140	UniSTS	GRCh37
Build 36	1	156,063,652 - 156,063,764	RGD	NCBI36
Celera	1	130,868,220 - 130,868,326	RGD
Cytogenetic Map	1	q21-q23	UniSTS
HuRef	1	129,154,899 - 129,155,003	UniSTS

SHGC-58141

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	157,801,908 - 157,802,128	UniSTS	GRCh37
Build 36	1	156,068,532 - 156,068,752	RGD	NCBI36
Celera	1	130,873,094 - 130,873,314	RGD
Cytogenetic Map	1	q21-q23	UniSTS
HuRef	1	129,159,771 - 129,159,991	UniSTS

D1S3339

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	157,801,062 - 157,801,314	UniSTS	GRCh37
Build 36	1	156,067,686 - 156,067,938	RGD	NCBI36
Celera	1	130,872,248 - 130,872,500	RGD
Cytogenetic Map	1	q21-q23	UniSTS
HuRef	1	129,158,925 - 129,159,177	UniSTS
GeneMap99-GB4 RH Map	1	589.92	UniSTS
Whitehead-RH Map	1	700.0	UniSTS
Whitehead-YAC Contig Map	1		UniSTS

RH12832

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	157,801,431 - 157,801,558	UniSTS	GRCh37
Build 36	1	156,068,055 - 156,068,182	RGD	NCBI36
Celera	1	130,872,617 - 130,872,744	RGD
Cytogenetic Map	1	q21-q23	UniSTS
HuRef	1	129,159,294 - 129,159,421	UniSTS
GeneMap99-GB4 RH Map	1	567.23	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	entire extraembryonic component	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	pharyngeal arch	renal system	reproductive system	respiratory system	sensory system
684	1205	1078	1463	2680	1157	1587	3	528	1326	437	1257	4300	3975	10	1763	1	430	1060	1034	94


RefSeq Transcripts	NM_001347698	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_005894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017002806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_054339616	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF011429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF147312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK292040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL139409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY358494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC033586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS538845	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CS615452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DA957550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U82812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENST00000368174 ⟹ ENSP00000357156

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	157,830,911 - 157,841,808 (-)	Ensembl

Ensembl Acc Id:

ENST00000484609

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p14 Ensembl	1	157,835,946 - 157,898,256 (-)	Ensembl

RefSeq Acc Id:

NM_001347698 ⟹ NP_001334627

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	157,827,068 - 157,841,808 (-)	NCBI
T2T-CHM13v2.0	1	156,964,145 - 156,978,876 (-)	NCBI

Sequence:

show sequence

GTCTTTGTCCCTCCTCTTAACATACTTGCAGCTAAAACTAAATATTGCTGCTTGGGGACCTCCTTCTAGCCTTAAATTTCAGCTCATCACCTTCACCTGCCTTGGTCATGGCTCTGCTATTCTCCTTG
ATCCTTGCCATTTGCACCAGACCTGGATTCCTAGCGTCTCCATCTGGAGTGCGGCTGGTGGGGGGCCTCCACCGCTGTGAAGGGCGGGTGGAGGTGGAACAGAAAGGCCAGTGGGGCACCGTGTGTGA
TGACGGCTGGGACATTAAGGACGTGGCTGTGTTGTGCCGGGAGCTGGGCTGTGGAGCTGCCAGCGGAACCCCTAGTGGTATTTTGTATGAGCCACCAGCAGAAAAAGAGCAAAAGGTCCTCATCCAAT
CAGTCAGTTGCACAGGAACAGAAGATACATTGGCTCAGTGTGAGCAAGAAGAAGTTTATGATTGTTCACATGATGAAGATGCTGGGGCATCGTGTGAGAACCCAGAGAGCTCTTTCTCCCCAGTCCCA
GAGGGTGTCAGGCTGGCTGACGGCCCTGGGCATTGCAAGGGACGCGTGGAAGTGAAGCACCAGAACCAGTGGTATACCGTGTGCCAGACAGGCTGGAGCCTCCGGGCCGCAAAGGTGGTGTGCCGGCA
GCTGGGATGTGGGAGGGCTGTACTGACTCAAAAACGCTGCAACAAGCATGCCTATGGCCGAAAACCCATCTGGCTGAGCCAGATGTCATGCTCAGGACGAGAAGCAACCCTTCAGGATTGCCCTTCTG
GGCCTTGGGGGAAGAACACCTGCAACCATGATGAAGACACGTGGGTCGAATGTGAAGATCCCTTTGACTTGAGACTAGTAGGAGGAGACAACCTCTGCTCTGGGCGACTGGAGGTGCTGCACAAGGGC
GTATGGGGCTCTGTCTGTGATGACAACTGGGGAGAAAAGGAGGACCAGGTGGTATGCAAGCAACTGGGCTGTGGGAAGTCCCTCTCTCCCTCCTTCAGAGACCGGAAATGCTATGGCCCTGGGGTTGG
CCGCATCTGGCTGGATAATGTTCGTTGCTCAGGGGAGGAGCAGTCCCTGGAGCAGTGCCAGCACAGATTTTGGGGGTTTCACGACTGCACCCACCAGGAAGATGTGGCTGTCATCTGCTCAGTGTAGG
TGGGCATCATCTAATCTGTTGAGTGCCTGAATAGAAGAAAAACACAGAAGAAGGGAGCATTTACTGTCTACATGACTGCATGGGATGAACACTGATCTTCTTCTGCCCTTGGACTGGGACTTATACTT
GGTGCCCCTGATTCTCAGGCCTTCAGAGTTGGATCAGAACTTACAACATCAGGTCTAGTTCTCAGGCCATCAGACATAGTTTGGAACTACATCACCACCTTTCCTATGTCTCCACATTGCACACAGCA
GATTCCCAGCCTCCATAATTGTGTGTATCAACTACTTAAATACATTATAACACACACACACACACACACACACACACACACACACACACACACATACACCATTTGTCCTGTTTCTCTGAAGAACTCTG
ACAAAATACAGATTTTGGTACTGAAAGAGATTCTAGAGGAACGGAATTTTAAGGATAAATTTTCTGAATTGGTTATGGGGTTTCTGAAATTGGCTCTATAATCTAATTAGATATAAAATTCTGGTAAC
TTTATTTACAATAATAAAGATAGCACTATGTGTTCATGG

hide sequence

RefSeq Acc Id:

NM_005894 ⟹ NP_005885

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	157,830,911 - 157,841,808 (-)	NCBI
GRCh37	1	157,796,861 - 157,811,634 (-)	NCBI
Build 36	1	156,067,330 - 156,078,175 (-)	NCBI Archive
HuRef	1	129,158,567 - 129,169,496 (-)	ENTREZGENE
CHM1_1	1	159,196,948 - 159,207,869 (-)	NCBI
T2T-CHM13v2.0	1	156,967,980 - 156,978,876 (-)	NCBI

Sequence:

show sequence

GTCTTTGTCCCTCCTCTTAACATACTTGCAGCTAAAACTAAATATTGCTGCTTGGGGACCTCCT
TCTAGCCTTAAATTTCAGCTCATCACCTTCACCTGCCTTGGTCATGGCTCTGCTATTCTCCTTGATCCTTGCCATTTGCACCAGACCTGGATTCCTAGCGTCTCCATCTGGAGTGCGGCTGGTGGGGG
GCCTCCACCGCTGTGAAGGGCGGGTGGAGGTGGAACAGAAAGGCCAGTGGGGCACCGTGTGTGATGACGGCTGGGACATTAAGGACGTGGCTGTGTTGTGCCGGGAGCTGGGCTGTGGAGCTGCCAGC
GGAACCCCTAGTGGTATTTTGTATGAGCCACCAGCAGAAAAAGAGCAAAAGGTCCTCATCCAATCAGTCAGTTGCACAGGAACAGAAGATACATTGGCTCAGTGTGAGCAAGAAGAAGTTTATGATTG
TTCACATGATGAAGATGCTGGGGCATCGTGTGAGAACCCAGAGAGCTCTTTCTCCCCAGTCCCAGAGGGTGTCAGGCTGGCTGACGGCCCTGGGCATTGCAAGGGACGCGTGGAAGTGAAGCACCAGA
ACCAGTGGTATACCGTGTGCCAGACAGGCTGGAGCCTCCGGGCCGCAAAGGTGGTGTGCCGGCAGCTGGGATGTGGGAGGGCTGTACTGACTCAAAAACGCTGCAACAAGCATGCCTATGGCCGAAAA
CCCATCTGGCTGAGCCAGATGTCATGCTCAGGACGAGAAGCAACCCTTCAGGATTGCCCTTCTGGGCCTTGGGGGAAGAACACCTGCAACCATGATGAAGACACGTGGGTCGAATGTGAAGATCCCTT
TGACTTGAGACTAGTAGGAGGAGACAACCTCTGCTCTGGGCGACTGGAGGTGCTGCACAAGGGCGTATGGGGCTCTGTCTGTGATGACAACTGGGGAGAAAAGGAGGACCAGGTGGTATGCAAGCAAC
TGGGCTGTGGGAAGTCCCTCTCTCCCTCCTTCAGAGACCGGAAATGCTATGGCCCTGGGGTTGGCCGCATCTGGCTGGATAATGTTCGTTGCTCAGGGGAGGAGCAGTCCCTGGAGCAGTGCCAGCAC
AGATTTTGGGGGTTTCACGACTGCACCCACCAGGAAGATGTGGCTGTCATCTGCTCAGGATAGTATCCTGGTGTTGCTTGACCTGGCCCCCCTGGCCCCGCCTGCCCTCTGCTTGTTCTCCTGAGCCC
TGATTATCCTCATACTCATTCTGGGGCTCAGGCTTGAGCCACTACTCCCTCATCCCCTCAGGAGTCTGAACACTGGGCTTATGCCTTACTCTCAGGGACAAGCAGCCCCCATTGCTGCCTGTAGATGT
GAGCTGTTGAGTTCCCTCTTGCTGGGGAAGATGAGCTTCCATGTATCCTGTGCTCAACCCTGACCCTTTGACACTGGTTCTGGCCTTTCCTGCCTTTTCTCAAGCTGCCTGGAATCCTCAAACCTGTC
ACTTTGGTCAGATGTGCAGACCATTACTAAGGTCTATGTCTGCAAACATTACTAATCTAGGTCCTATTACTAATCTATGTCTGCAAACATTAAAGGAATGAAACAATGAAAGGAACATTTGAAAGAAA
ATGTGGGTAGACAATTTCTTGCAACTTGGGGGAAAGTTTAGAATTCTTTTGATTGGACTACTTTTTTTTTTTTTCCTCAAGCTTCAGGTGACCACAATAGCAACACCTCCCTATTCTGTTATTTCTTA
GTGTAGGTAGACAATTCTTTCAGGAGCAGAGCAGCGTCCTATAATCCTAGACCTTTTCATGACGTGTAAAAAATGATGTTTCATCCTCTGATTGCCCCAATAAAAATCTTTGTTGTCCATCCCTATAC
AACCTGCCAACATGGTTGACATTTAATGAGAGGAATGTCAAAAATACATTTTACTTTATTCAAAGAAAAATATATTGGTTACTGGGAAAAGGTCAAGAAAGAGGCAGAAAGAGATCAGGGAGGGCTAA
AGTTGTGTCTTATGCCAAGCGAAAGTGAAAAATATCATTTTCACTTTATCAACTGAGACTTTGGGGCCTGTAAGCTTGAGGCAAGACAGAAATAAGAGAATCAAGACTTGATTGTAAAAATTGACAAC
TTTAGATTCTGAGGCTAGGCTGAGTACTTATTATACGGCTACATTTACACATTTACACTTATCTAATAAATCAGATTTCACAGTCTCAACAA

hide sequence

RefSeq Acc Id:

XM_017002806 ⟹ XP_016858295

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	157,827,068 - 157,841,808 (-)	NCBI

Sequence:

show sequence

GATCATCTGATAATGCTTTGCCTGCACTCAGGACCTGTCTTTGTCCCTCCTCTTAACATACTTGCAGCTAAAACTAAATATTGCTGCTTGGGGACCTCCTTCTAGCCTTAAATTTCAGCTCATCACCT
TCACCTGCCTTGGTCATGGCTCTGCTATTCTCCTTGATCCTTGCCATTTGCACCAGACCTGGATTCCTAGCGTCTCCATCTGGAGTGCGGCTGGTGGGGGGCCTCCACCGCTGTGAAGGGCGGGTGGA
GGTGGAACAGAAAGGCCAGTGGGGCACCGTGTGTGATGACGGCTGGGACATTAAGGACGTGGCTGTGTTGTGCCGGGAGCTGGGCTGTGGAGCTGCCAGCGGAACCCCTAGTGGTATTTTGTATGAGC
CACCAGCAGAAAAAGAGCAAAAGGTCCTCATCCAATCAGTCAGTTGCACAGGAACAGAAGATACATTGGCTCAGTGTGAGCAAGAAGAAGTTTATGATTGTTCACATGATGAAGATGCTGGGGCATCG
TGTGAGAACCCAGAGAGCTCTTTCTCCCCAGTCCCAGAGGGTGTCAGGCTGGCTGACGGCCCTGGGCATTGCAAGGGACGCGTGGAAGTGAAGCACCAGAACCAGTGGTATACCGTGTGCCAGACAGG
CTGGAGCCTCCGGGCCGCAAAGGTGGTGTGCCGGCAGCTGGGATGTGGGAGGGCTGTACTGACTCAAAAACGCTGCAACAAGCATGCCTATGGCCGAAAACCCATCTGGCTGAGCCAGATGTCATGCT
CAGGACGAGAAGCAACCCTTCAGGATTGCCCTTCTGGGCCTTGGGGGAAGAACACCTGCAACCATGATGAAGACACGTGGGTCGAATGTGAAGATCCCTTTGACTTGAGACTAGTAGGAGGAGACAAC
CTCTGCTCTGGGCGACTGGAGGTGCTGCACAAGGGCGTATGGGGCTCTGTCTGTGATGACAACTGGGGAGAAAAGGAGGACCAGGTGGTATGCAAGCAACTGGGCTGTGGGAAGTCCCTCTCTCCCTC
CTTCAGAGACCGGAAATGCTATGGCCCTGGGGTTGGCCGCATCTGGCTGGATAATGTTCGTTGCTCAGGGGAGGAGCAGTCCCTGGAGCAGTGCCAGCACAGATTTTGGGGGTTTCACGACTGCACCC
ACCAGGAAGATGTGGCTGTCATCTGCTCAGGTGGGCATCATCTAATCTGTTGAGTGCCTGAATAGAAGAAAAACACAGAAGAAGGGAGCATTTACTGTCTACATGACTGCATGGGATGAACACTGATC
TTCTTCTGCCCTTGGACTGGGACTTATACTTGGTGCCCCTGATTCTCAGGCCTTCAGAGTTGGATCAGAACTTACAACATCAGGTCTAGTTCTCAGGCCATCAGACATAGTTTGGAACTACATCACCA
CCTTTCCTATGTCTCCACATTGCACACAGCAGATTCCCAGCCTCCATAATTGTGTGTATCAACTACTTAAATACATTATAACACACACACACACACACACACACACACACACACACACACACACATAC
ACCATTTGTCCTGTTTCTCTGAAGAACTCTGACAAAATACAGATTTTGGTACTGAAAGAGATTCTAGAGGAACGGAATTTTAAGGATAAATTTTCTGAATTGGTTATGGGGTTTCTGAAATTGGCTCT
ATAATCTAATTAGATATAAAATTCTGGTAACTTTATTTACAATAATAAAGATAGCACTATGTGTTCA

hide sequence

RefSeq Acc Id:

XM_054339616 ⟹ XP_054195591

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
T2T-CHM13v2.0	1	156,964,148 - 156,978,876 (-)	NCBI


Protein RefSeqs	NP_001334627	(Get FASTA)	NCBI Sequence Viewer
	NP_005885	(Get FASTA)	NCBI Sequence Viewer
	XP_016858295	(Get FASTA)	NCBI Sequence Viewer
	XP_054195591	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB91989	(Get FASTA)	NCBI Sequence Viewer
	AAD01446	(Get FASTA)	NCBI Sequence Viewer
	AAH33586	(Get FASTA)	NCBI Sequence Viewer
	AAQ88858	(Get FASTA)	NCBI Sequence Viewer
	BAF84729	(Get FASTA)	NCBI Sequence Viewer
	CAM90872	(Get FASTA)	NCBI Sequence Viewer
	CAO02287	(Get FASTA)	NCBI Sequence Viewer
	EAW52859	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSP00000357156
	ENSP00000357156.4
GenBank Protein	O43866	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_005885 ⟸ NM_005894
- Peptide Label:	isoform 1 precursor
- UniProtKB:	A8K7M5 (UniProtKB/Swiss-Prot), Q6UX63 (UniProtKB/Swiss-Prot), O43866 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALLFSLILAICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPE SSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGR LEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSG hide sequence

RefSeq Acc Id:

XP_016858295 ⟸ XM_017002806

- Peptide Label:

isoform X1

- Sequence:

show sequence

MALLFSLILAICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPE
SSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGR
LEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSGGHHLIC

hide sequence

RefSeq Acc Id:	NP_001334627 ⟸ NM_001347698
- Peptide Label:	isoform 2 precursor
- UniProtKB:	O43866 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MALLFSLILAICTRPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEVYDCSHDEDAGASCENPE SSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGR LEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICSV hide sequence

Ensembl Acc Id:

ENSP00000357156 ⟸ ENST00000368174

RefSeq Acc Id:	XP_054195591 ⟸ XM_054339616
- Peptide Label:	isoform X1

Protein Domains

SRCR

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O43866-F1-model_v2	AlphaFold	O43866	1-347	view protein structure

RGD ID:

6857668

Promoter ID:

EPDNEW_H1999

Type:

initiation region

Name:

CD5L_2

Description:

CD5 molecule like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H2000

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	157,841,808 - 157,841,868	EPDNEW

Database	Acc Id	Source(s)
COSMIC	CD5L	COSMIC
Ensembl Genes	ENSG00000073754	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000368174	ENTREZGENE
	ENST00000368174.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.10.250.10	UniProtKB/Swiss-Prot
GTEx	ENSG00000073754	GTEx
HGNC ID	HGNC:1690	ENTREZGENE
Human Proteome Map	CD5L	Human Proteome Map
InterPro	SRCR	UniProtKB/Swiss-Prot
	SRCR-like_dom_sf	UniProtKB/Swiss-Prot
KEGG Report	hsa:922	UniProtKB/Swiss-Prot
NCBI Gene	922	ENTREZGENE
OMIM	602592	OMIM
PANTHER	CD5 ANTIGEN-LIKE	UniProtKB/Swiss-Prot
	SRCR DOMAIN-CONTAINING PROTEIN	UniProtKB/Swiss-Prot
Pfam	SRCR	UniProtKB/Swiss-Prot
PharmGKB	PA26229	PharmGKB
PRINTS	SPERACTRCPTR	UniProtKB/Swiss-Prot
PROSITE	SRCR_1	UniProtKB/Swiss-Prot
	SRCR_2	UniProtKB/Swiss-Prot
SMART	SM00202	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56487	UniProtKB/Swiss-Prot
UniProt	A8K7M5	ENTREZGENE
	CD5L_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
	Q6UX63	ENTREZGENE
UniProt Secondary	A8K7M5	UniProtKB/Swiss-Prot
	Q6UX63	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-08	CD5L	CD5 molecule like		CD5 molecule-like	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Human Phenotype Annotations - ClinVar

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Human Phenotype Annotations - ClinVar