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Gene: Vopp1 (vesicular, overexpressed in cancer, prosurvival protein 1) Mus musculus

Analyze

Symbol:

Vopp1

Name:

vesicular, overexpressed in cancer, prosurvival protein 1

RGD ID:

1315143

MGI Page

MGI

Description:

Predicted to enable enzyme binding activity. Predicted to be located in cytoplasmic vesicle membrane; late endosome; and lysosome. Predicted to be active in organelle membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and neural retina. Orthologous to human VOPP1 (VOPP1 WW domain binding protein).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Ecop; EGFR-coamplified and overexpressed protein; WW domain binding protein VOPP1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	VOPP1 (VOPP1 WW domain binding protein)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Vopp1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Vopp1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	VOPP1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	VOPP1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Vopp1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	VOPP1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	VOPP1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Vopp1 (VOPP1 WW domain binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Vopp1 (VOPP1 WW domain binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	VOPP1 (VOPP1 WW domain binding protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-24c2.9	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	vopp1 (VOPP1 WW domain binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Xenopus tropicalis (tropical clawed frog):	vopp1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	57,704,792 - 57,802,144 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	57,752,264 - 57,827,983 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	57,727,807 - 57,825,159 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	57,702,258 - 57,775,119 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	57,681,842 - 57,754,703 (-)	NCBI		MGSCv36	mm8
Celera	6	58,495,992 - 58,569,211 (-)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.82	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

autistic disorder (ISO)

Experimental Liver Cirrhosis (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (EXP)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (EXP)

5-chloro-7-iodoquinolin-8-ol (ISO)

6-propyl-2-thiouracil (ISO)

acetamide (ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

benzene (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (EXP)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (EXP)

C60 fullerene (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (EXP)

Cuprizon (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

diethyl phthalate (EXP)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

folic acid (EXP)

fulvestrant (ISO)

furan (ISO)

gentamycin (ISO)

glyphosate (ISO)

indometacin (ISO)

isotretinoin (ISO)

lead(0) (ISO)

N-nitrosodiethylamine (EXP)

N-nitrosodimethylamine (ISO)

oxaliplatin (ISO)

ozone (ISO)

perfluorohexanesulfonic acid (EXP)

phenobarbital (EXP)

potassium dichromate (EXP)

Salinomycin (ISO)

SB 431542 (ISO)

sodium arsenite (EXP,ISO)

thioacetamide (ISO)

titanium dioxide (EXP)

topotecan (ISO)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

cytoplasmic vesicle membrane (ISO,ISS)

endosome (ISO)

late endosome (ISO)

late endosome membrane (IEA)

lysosomal membrane (IEA)

lysosome (ISO)

organelle membrane (IBA,ISO,ISS)

Molecular Function

enzyme binding (IEA,ISO)

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal startle reflex (IEA)

impaired pupillary reflex (IEA)

mydriasis (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:12466851	PMID:12477932	PMID:15226823	PMID:16141072	PMID:16141073	PMID:21267068	PMID:21677750
PMID:21873635	PMID:24194600	PMID:34321999	PMID:38187761	PMID:38355793

Genomics

Comparative Map Data

Vopp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	57,704,792 - 57,802,144 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	57,752,264 - 57,827,983 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	57,727,807 - 57,825,159 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	57,702,258 - 57,775,119 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	57,681,842 - 57,754,703 (-)	NCBI		MGSCv36	mm8
Celera	6	58,495,992 - 58,569,211 (-)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	27.82	NCBI

VOPP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	55,434,964 - 55,572,502 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	55,436,056 - 55,572,988 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	55,538,301 - 55,640,195 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	55,505,800 - 55,607,694 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	55,641,499 - 55,692,013 (-)	NCBI		Celera
Cytogenetic Map	7	p11.2	NCBI
HuRef	7	55,373,863 - 55,475,623 (-)	NCBI		HuRef
CHM1_1	7	55,540,980 - 55,642,824 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	55,594,635 - 55,732,784 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	55,542,585 - 55,644,447 (-)	NCBI

Vopp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	88,692,784 - 88,762,903 (+)	NCBI		GRCr8
mRatBN7.2	4	87,363,678 - 87,432,747 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	87,363,477 - 87,450,375 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	92,585,343 - 92,654,451 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	88,360,746 - 88,429,856 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	86,723,766 - 86,792,952 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	88,441,067 - 88,515,141 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	88,441,067 - 88,515,138 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	153,266,271 - 153,337,779 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	87,116,146 - 87,186,828 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	87,358,867 - 87,429,606 (+)	NCBI
Celera	4	82,130,454 - 82,198,637 (+)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Vopp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955456	141,848 - 179,859 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955456	88,525 - 181,480 (+)	NCBI	ChiLan1.0	ChiLan1.0

VOPP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	60,300,895 - 60,402,679 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	108,625,620 - 108,727,401 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	56,061,704 - 56,163,517 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	56,372,027 - 56,422,495 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	56,372,027 - 56,463,310 (-)	Ensembl	panpan1.1		panPan2

VOPP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	6,282,050 - 6,387,687 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	6,282,426 - 6,386,703 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	6,127,459 - 6,232,357 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	6,324,333 - 6,429,496 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	6,324,335 - 6,430,510 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	6,314,150 - 6,419,178 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	6,288,335 - 6,387,218 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	6,394,579 - 6,499,861 (-)	NCBI		UU_Cfam_GSD_1.0

Vopp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	109,696,141 - 109,793,922 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936678	95,041 - 191,488 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936678	95,655 - 193,415 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VOPP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	48,607,919 - 48,693,815 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	48,607,923 - 48,693,858 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

VOPP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	3,295,395 - 3,395,206 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	3,295,521 - 3,397,529 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666062	19,196,523 - 19,296,703 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vopp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	375,944 - 469,111 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	375,651 - 470,841 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Vopp1
3573 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1474
Count of miRNA genes:	761
Interacting mature miRNAs:	966
Transcripts:	ENSMUST00000114297, ENSMUST00000127485, ENSMUST00000143953, ENSMUST00000145608
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96633110	Mouse
1301266	Lmr4_m	leishmaniasis resistance 4 (mouse)			Not determined		6	42093358	76093500	Mouse
26884441	Sklq3_m	skull length QTL 3, 5 week (mouse)					6	7600000	80576983	Mouse
12910785	Pwgrq16_m	post-weaning growth rate QTL 16 (mouse)					6	43803747	77788506	Mouse
11252142	Mom12_m	Modifier of Min 12 (mouse)					6	33872261	67872400	Mouse
4140983	Srilp_m	sleep response to influenza, light phase (mouse)			Not determined			48703490	75424693	Mouse
12910798	Pwgrq5_m	pre-weaning growth rate QTL 5 (mouse)					6	43803747	77788506	Mouse
1300959	Lxw2_m	lupus BXSB x NZW 2 (mouse)			Not determined		6	33872261	67872400	Mouse
1300767	Aliq4_m	acute lung injury QTL 4 (mouse)			Not determined		6	36273332	70273435	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46912919	136400690	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48696934	125336963	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96633110	Mouse
14746995	Manh60_m	mandible shape 60 (mouse)					6	37202662	71202662	Mouse
12910807	Pwbwq11_m	post-weaning body weight QTL 11 (mouse)					6	43803747	77788506	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48696934	148351498	Mouse
1301254	Skts11_m	skin tumor susceptibility 11 (mouse)			Not determined		6	51156134	85156284	Mouse
1357442	Dbts1_m	diabetes 1 (mouse)			Not determined		6	18234147	73364675	Mouse
12910802	Pwbwq12_m	post-weaning body weight QTL 12 (mouse)					6	43803747	77788506	Mouse
4141094	Hrtr1_m	heart rate 1 (mouse)			Not determined			36741463	70741463	Mouse
1300618	Pgia19_m	proteoglycan induced arthritis 19 (mouse)			Not determined		6	45290993	87403016	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48703490	125333748	Mouse
4141988	Obrq3_m	obesity resistance QTL 3 (mouse)			Not determined			28290993	62291115	Mouse
4141028	Mclr_m	methylcholanthrene lymphoma resistance (mouse)			Not determined			54350411	88356155	Mouse
12910809	Pwbwq10_m	post-weaning body weight QTL 10 (mouse)					6	43803747	77788506	Mouse
1301326	Trbv4c2_m	T cell receptor beta variable 4 (mouse)			Not determined		6	40868230	71356155	Mouse
1300556	Cia6_m	collagen induced arthritis QTL 6 (mouse)			Not determined		6	4464884	87403016	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38646560	92584431	Mouse
12910820	Ogrq3_m	overall growth rate QTL 3 (mouse)					6	43803747	77788506	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45290993	128811995	Mouse
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	3050001	117476961	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139076998	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96633110	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96633110	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52138693	116132228	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56285194	90285194	Mouse
4141782	Mrdq5_m	modifier of retinal degeneration QTL 5 (mouse)			Not determined			32827585	78215957	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56285194	90285194	Mouse
10412213	Sxbq2_m	SGC/Knj cross B6 QTL 2 (mouse)			Not determined		6	19912685	71299759	Mouse
12880424	V25Dq4_m	vitamin D inactive form serum level QTL 4 (mouse)					6	41576985	75576985	Mouse
12880425	V25Dq5_m	vitamin D inactive form serum level QTL 5 (mouse)					6	32676980	66676980	Mouse
11040600	Lmr4c_m	leishmaniasis resistance 4c (mouse)					6	42093358	76093500	Mouse
4141454	Obrq4_m	obesity resistance QTL 4 (mouse)			Not determined			31703499	65703611	Mouse
11040601	Lmr4a_m	leishmaniasis resistance 4a (mouse)					6	42093358	76093500	Mouse
14700690	Ccs6_m	colon cancer susceptibility 6 (mouse)					6	23776934	57776934	Mouse
11533915	Mts4_m	mammary tumor susceptibility 4 (mouse)					6	42093358	76093500	Mouse
10043885	Cia6c_m	collagen induced arthritis QTL 6c (mouse)			Not determined		6	44442805	71096451	Mouse
1357539	Bsbob3_m	BSB obesity 3 (mouse)			Not determined		6	36448456	70448576	Mouse
13208564	Bmiq7_m	body mass index QTL 7 (mouse)					6	24999999	79976983	Mouse

Markers in Region

AW146242

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	57,752,368 - 57,752,483	UniSTS	GRCm38
MGSCv37	6	57,702,362 - 57,702,477	UniSTS	GRCm37
Celera	6	58,496,096 - 58,496,211	UniSTS
Cytogenetic Map	6	B3	UniSTS
Whitehead/MRC_RH	6	570.84	UniSTS

UniSTS:235454

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	57,752,742 - 57,752,999	UniSTS	GRCm38
MGSCv37	6	57,702,736 - 57,702,993	UniSTS	GRCm37
Celera	6	58,496,470 - 58,496,727	UniSTS
Cytogenetic Map	6	B3	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001411586	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411587	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411588	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411589	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_146168	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_177289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_177290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_177291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127307	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC144816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK031812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK158041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK165256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK170152	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK170832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC024822	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC024884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000114297 ⟹ ENSMUSP00000109936

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,729,250 - 57,802,144 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,752,265 - 57,825,159 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000127485 ⟹ ENSMUSP00000115377

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,704,792 - 57,802,121 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,727,807 - 57,825,136 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000143953

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,739,552 - 57,801,625 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,762,567 - 57,824,640 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000145608 ⟹ ENSMUSP00000145084

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,735,332 - 57,802,139 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,758,347 - 57,825,154 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000203212 ⟹ ENSMUSP00000144859

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,739,434 - 57,802,139 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,762,449 - 57,825,154 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000204878 ⟹ ENSMUSP00000144953

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	6	57,731,548 - 57,802,135 (-)	Ensembl
GRCm38.p6 Ensembl	6	57,754,563 - 57,825,150 (-)	Ensembl

RefSeq Acc Id:

NM_001411586 ⟹ NP_001398515

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,774,056 (-)	NCBI

RefSeq Acc Id:

NM_001411587 ⟹ NP_001398516

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI

RefSeq Acc Id:

NM_001411588 ⟹ NP_001398517

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI

RefSeq Acc Id:

NM_001411589 ⟹ NP_001398518

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,801,626 (-)	NCBI

RefSeq Acc Id:

NM_001411590 ⟹ NP_001398519

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,250 - 57,801,626 (-)	NCBI

RefSeq Acc Id:

NM_146168 ⟹ NP_666280

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI
GRCm38	6	57,752,264 - 57,825,125 (-)	NCBI
MGSCv37	6	57,702,258 - 57,775,119 (-)	RGD
Celera	6	58,495,992 - 58,569,211 (-)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

GGCACGTCCTCGAGCTCCGCCGGCTTGCCGCGCGTCCTTCTGCCGGCTTCAGCTCGTATCCCCG
GAGTCCACCCGCCCGTCCCGGGGTGCGGACTGGCCCTGAGCTGGCCGTACAGCCCGGCTTCGGA
CGGTCCTCGCTGGAGCCATGGGCCGCCGGCTCGGCAGGGTGGCGGCGCTGCTGCTCGGGCTGCT
AGTGGAGTGCACTGAGGCCAAAAAACATTGCTGGTATTTTGAAGGACTCTATCCCACATACTAT
ATATGCCGTTCCTATGAAGACTGCTGTGGCTCCAGGTGCTGTGTGAGGGCCCTTTCCATACAGA
GGCTGTGGTATTTTTGGTTCCTGCTGATGATGGGTGTGCTGTTCTGCTGTGGTGCCGGTTTCTT
CATTCGCCGGCGCATGTATCCGCCACCACTCATTGAGGAGCCCACATTCAATGTGTCCTATACC
AGGCAGCCACCAAATCCTGCTCCAGGAGCACAGCAAATGGGACCGCCATATTACACCGACCCTG
GAGGACCCGGGATGAATCCTGTTGGCAATACCATGGCTATGGCTTTCCAGGTCCAGCCCAATTC
ACCTCACGGAGGCACAACTTACCCACCCCCTCCTTCCTACTGCAACACGCCTCCACCCCCCTAT
GAACAGGTGGTGAAGGACAAGTAGCAAGATGCTACATCAAAGGCAAAGAGGATGGACAGGCCCT
TTTGTTTACCTTCCCATCCTCACCGATACTTGCTGATAGGGTGGTCCAAGGGAAAACTTGGATA
TTCTCAAAGCAAGCCCAGCTCTCTTTCAAGTCTTTTGTGGAGGACATTTGAATCCACACTGTCT
CCTCTGTTGCTTCTGTTTCTGATGTAGTCTGTGCTCTCTGAGAGAGTGTGGCAACAGTCCCTGA
GGGTTGATATTCCTAGGGTGTCCAGGGTAGATCCTCGGGAGAGAGGCTAAGGGGAAAGGAAGGC
ATAGCCTGTGTGTTAGGGGGCAGATAAAGTGGTCAGGCTGAGATAAGACTCACATGATGCAGTA
GTTGGCAGTGAACTTCGAAGAGACACTATCCACCATCCCAGCCCATTCTCCTAATAGAAGCTGT
GGGGCTGTGTTGTTGATGCTCTTTGGTCTCCACTCACATTTTGAAAATAGGCTTTCCTCTGCAG
GAATAGGAAAGACCCAAGTACATATTTGCTTCCACTTAAAAATGAGGGTCAGAACCAGGCCTCA
GTTGGACATCTATAGTTAAATAAAGGCCATTAGAGAGGGGAAATCTTTAAGTTAGGGGAAATTC
TCTAAATGGAGACATTGCGTTTTATGAATCATCGTCTGGCTTTTCTTTTAGTGCATGTATTGAA
GTGAGGGTGTCCTTTGAGATCAGATGGGGAGAGTGAACTCTGCGGGGGGTGGGGTGTCTCTACT
CAGAGGGCTCCAACACCCTTTTCTTAGGTAGTTCTGGTGATGGGTTTTATGGGCACTATAGAGC
TGAGGGGCACATTAGGCCGGGTAGTTACATTGACCCTTGGAGAGGAAGAGGACAGCCAAAGAAA
CTCAGCAAAGCAAGACCAGCATTGCTGAGTTAGAGCTAGGGTTGTATGTGATCCCAACAGAGAT
GTGCTGGCCTCAGAAGAGGGGACGTTTGTGGATAGAGCCGTGAAAACCTACTTAGTTGCACAGA
TGACATAATCAAAAGTAGAGAAAGAAGTGTAGTTAGAGATGCCATTTCCCAGGTGAGAATCAGA
GCTCATCCATAGATTTACAAGTAGTGGCTGGAGTTAACAGTATGGAGTTCTTTTCCCTTGCGTA
GTTAGTCACGTTGATGTGTATTTAAACCCAGGTTGAGACCTTGTGTACTAAGAGCAAGGAAGTA
TAGCTAAGATGTCTAGATTATTTATATGTAGTATGGTGGGGAGTGGGGCTGCAAGGAAGGGGGC
TGACATTGTAAATGAGAAAATCAGAGCCATTTGATAAACTGTTACTTGTTGGATCAGGCATCCA
AAAGTGTCTCTTGAGTGGACATTGAGTATTCTTTACCACCTACAAGACCAGGAGGCATGGTGTC
ATTCTCCATTGGGGTATTTATATGAGGTAGAGGTTCAGGAATCGACAGTAGCTGTGTGGGCTTA
GTTTAAGGACTGAAAGCATAGGGACTGGTAGACAGTTTCATAGGAAACTGCGGGGAAGGAATGG
ATACCTTTAAAGACAGTTTGTGGATGCAGATGCTGCCACCCATCATTGAGCACCCTTGTGTCTC
TGGCTTCCTGTCACTGGATCCAGTACCCCTCCATGCTTGGGTCCTTGTTTTACATAAGACAACA
AAGCACAATGTCTGCTGTTTACAATCAAGACGACTACATGGTCCAAACATTTCTTCTCTCTTCT
ATCACTTGTGGCTTTAACTTCCATTTCCTCCGTTCCTTTTTAAAATCAAGAAGCACAGTCAGAG
CTGCCCCTGGGATTGCATCAGGGAACGGCTGATCAAGGCATTCAGTGTCCATGACTAAATCTTA
TCTTTTTGATAGCAAATCCTTTTAAGAAACTGAACAATTGCTAAGGCTCAGCAATTTTATACTC
CAATGTCTGTGTAAGGTAAATTTTGTTTGCCATTGAGCCCACATTGGAATTCCTTCTGACGTCA
ACACTGACAATGCCTATGGAAATTGCACTTCTGGGTATATGTCCCAGCATCCTTGTTTTCTTAT
GTTTGGTGAGTAAGGCTCACCCCTTCCAGCAGCTCTACTTCTGTGTGCTGAGGTCCTGTAGAGC
CGGGGCTTGGGCACAGACATGAGGCAGACTTGTGCATGCTCTTTCTTGGCAACACTTGGCTCAT
ATTTCTTGTTCTCTTTTGATAGAGTCCTGTTTCCTATGTATTTAAAAAATAATAAAAGTGAATT
TAGTCAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NR_177289

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI

RefSeq Acc Id:

NR_177290

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,802,110 (-)	NCBI

RefSeq Acc Id:

NR_177291

RefSeq Status:

VALIDATED

Type:

NON-CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	57,729,249 - 57,801,626 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001398515	(Get FASTA)	NCBI Sequence Viewer
	NP_001398516	(Get FASTA)	NCBI Sequence Viewer
	NP_001398517	(Get FASTA)	NCBI Sequence Viewer
	NP_001398518	(Get FASTA)	NCBI Sequence Viewer
	NP_001398519	(Get FASTA)	NCBI Sequence Viewer
	NP_666280	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH24822	(Get FASTA)	NCBI Sequence Viewer
	BAC27198	(Get FASTA)	NCBI Sequence Viewer
	BAC27562	(Get FASTA)	NCBI Sequence Viewer
	BAE34331	(Get FASTA)	NCBI Sequence Viewer
	BAE41599	(Get FASTA)	NCBI Sequence Viewer
	BAE42060	(Get FASTA)	NCBI Sequence Viewer
	EDL04747	(Get FASTA)	NCBI Sequence Viewer
	EDL04748	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000109936
	ENSMUSP00000109936.3
	ENSMUSP00000115377.2
	ENSMUSP00000144859.2
	ENSMUSP00000144953.2
	ENSMUSP00000145084.2
GenBank Protein	Q8R1C3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_666280 ⟸ NM_146168
- Peptide Label:	isoform a precursor
- UniProtKB:	Q8R1C3 (UniProtKB/Swiss-Prot), Q8C0B7 (UniProtKB/Swiss-Prot), Q3TZ79 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGRRLGRVAALLLGLLVECTEAKKHCWYFEGLYPTYYICRSYEDCCGSRCCVRALSIQRLWYFW FLLMMGVLFCCGAGFFIRRRMYPPPLIEEPTFNVSYTRQPPNPAPGAQQMGPPYYTDPGGPGMN PVGNTMAMAFQVQPNSPHGGTTYPPPPSYCNTPPPPYEQVVKDK hide sequence

Ensembl Acc Id:

ENSMUSP00000144859 ⟸ ENSMUST00000203212

Ensembl Acc Id:

ENSMUSP00000115377 ⟸ ENSMUST00000127485

Ensembl Acc Id:

ENSMUSP00000144953 ⟸ ENSMUST00000204878

Ensembl Acc Id:

ENSMUSP00000145084 ⟸ ENSMUST00000145608

Ensembl Acc Id:

ENSMUSP00000109936 ⟸ ENSMUST00000114297

RefSeq Acc Id:	NP_001398516 ⟸ NM_001411587
- Peptide Label:	isoform c

RefSeq Acc Id:	NP_001398517 ⟸ NM_001411588
- Peptide Label:	isoform c

RefSeq Acc Id:	NP_001398518 ⟸ NM_001411589
- Peptide Label:	isoform c

RefSeq Acc Id:	NP_001398515 ⟸ NM_001411586
- Peptide Label:	isoform b

RefSeq Acc Id:	NP_001398519 ⟸ NM_001411590
- Peptide Label:	isoform c

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R1C3-F1-model_v2	AlphaFold	Q8R1C3	1-172	view protein structure

Promoters

RGD ID:

6840149

Promoter ID:

MM_KWN:46162

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_2Hour, Brain

Transcripts:

ENSMUST00000042127

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	57,740,569 - 57,741,069 (-)	MPROMDB

RGD ID:

6889846

Promoter ID:

EPDNEW_M8374

Type:

initiation region

Name:

Vopp1_1

Description:

Mus musculus vesicular, overexpressed in cancer, prosurvivalprotein 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	57,825,121 - 57,825,181	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2141658	AgrOrtholog
Ensembl Genes	ENSMUSG00000037788	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000114297	ENTREZGENE
	ENSMUST00000114297.5	UniProtKB/Swiss-Prot
	ENSMUST00000127485.8	UniProtKB/Swiss-Prot
	ENSMUST00000145608.7	UniProtKB/TrEMBL
	ENSMUST00000203212.3	UniProtKB/TrEMBL
	ENSMUST00000204878.3	UniProtKB/TrEMBL
InterPro	VOPP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:232023	UniProtKB/Swiss-Prot
MGD	MGI:2141658	ENTREZGENE
NCBI Gene	Vopp1	ENTREZGENE
PANTHER	PTHR14971	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Vopp1	PhenoGen
PRINTS	VOPPROTEIN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0N4SUX3_MOUSE	UniProtKB/TrEMBL
	A0A0N4SV49_MOUSE	UniProtKB/TrEMBL
	A0A0N4SVF9_MOUSE	UniProtKB/TrEMBL
	Q3TZ79	ENTREZGENE
	Q8C0B7	ENTREZGENE
	Q8R1C3	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q3TZ79	UniProtKB/Swiss-Prot
	Q8C0B7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-08-26	Vopp1	vesicular, overexpressed in cancer, prosurvival protein 1	AW146242	expressed sequence AW146242	Symbol and/or name updated	27372883	PROVISIONAL
2024-08-21	AW146242	expressed sequence AW146242	Vopp1	vesicular, overexpressed in cancer, prosurvival protein 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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