Gba2 (glucosidase beta 2) - Rat Genome Database

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Gene: Gba2 (glucosidase beta 2) Mus musculus
Analyze
Symbol: Gba2
Name: glucosidase beta 2
RGD ID: 1313722
MGI Page MGI
Description: Enables glucosylceramidase activity; glucosyltransferase activity; and steryl-beta-glucosidase activity. Involved in several processes, including glucosylceramide catabolic process; lipid glycosylation; and regulation of protein polymerization. Located in Golgi membrane; cytosol; and endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; dorsal root ganglion; epidermis; liver; and neural retina. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 46. Orthologous to human GBA2 (glucosylceramidase beta 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-glucocerebrosidase 2; beta-glucosidase 2; bile acid; bile acid beta-glucosidase GBA2; bile acid glucosyl transferase GBA2; cholesterol glucosyltransferase GBA2; cholesteryl-beta-glucosidase GBA2; F630034E04; glucosidase, beta (bile acid) 2; glucosylceramidase 2; NLGase; non-lysosomal cholesterol glycosyltransferase; non-lysosomal galactosylceramidase; non-lysosomal glucosylceramidase; non-lysosomal glycosylceramidase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,566,928 - 43,578,893 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,566,928 - 43,578,873 (-)EnsemblGRCm39 Ensembl
GRCm38443,566,928 - 43,578,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,566,928 - 43,578,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv37443,579,800 - 43,591,736 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,588,037 - 43,599,649 (-)NCBIMGSCv36mm8
Celera443,600,917 - 43,612,853 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12520002   PMID:15226823   PMID:15368895   PMID:15489334   PMID:15782199   PMID:16141072  
PMID:16141073   PMID:16778019   PMID:17080196   PMID:17105727   PMID:17848577   PMID:19092943   PMID:19809509   PMID:19933215   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22659419  
PMID:22764777   PMID:23096701   PMID:23250757   PMID:23867462   PMID:23880767   PMID:24639522   PMID:25803043   PMID:26275242   PMID:26724485   PMID:28258214   PMID:28373486   PMID:30662006  
PMID:30973865   PMID:31299418   PMID:32144204   PMID:32325033   PMID:32554809   PMID:38355793  


Genomics

Comparative Map Data
Gba2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,566,928 - 43,578,893 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,566,928 - 43,578,873 (-)EnsemblGRCm39 Ensembl
GRCm38443,566,928 - 43,578,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,566,928 - 43,578,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv37443,579,800 - 43,591,736 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,588,037 - 43,599,649 (-)NCBIMGSCv36mm8
Celera443,600,917 - 43,612,853 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.05NCBI
GBA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,736,866 - 35,749,228 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,736,866 - 35,749,228 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,736,863 - 35,749,225 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,726,863 - 35,739,225 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,726,863 - 35,739,225NCBI
Celera935,670,413 - 35,682,776 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,692,483 - 35,704,845 (-)NCBIHuRef
CHM1_1935,737,266 - 35,749,629 (-)NCBICHM1_1
T2T-CHM13v2.0935,757,546 - 35,769,909 (-)NCBIT2T-CHM13v2.0
Gba2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,618,176 - 62,630,160 (-)NCBIGRCr8
mRatBN7.2557,822,389 - 57,834,522 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,822,389 - 57,834,072 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,802,219 - 59,813,868 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,621,035 - 61,632,684 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,592,498 - 61,604,154 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,068,081 - 59,079,719 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,068,081 - 59,079,719 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,592,675 - 63,604,313 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,045,397 - 60,057,035 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,045,575 - 60,057,254 (-)NCBI
Celera556,402,961 - 56,414,599 (-)NCBICelera
Cytogenetic Map5q22NCBI
Gba2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955472553,556 - 564,411 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955472553,556 - 564,411 (+)NCBIChiLan1.0ChiLan1.0
GBA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21188,839,627 - 88,851,447 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1988,845,445 - 88,857,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0935,587,876 - 35,599,971 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1936,390,407 - 36,402,949 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl936,390,409 - 36,402,949 (-)Ensemblpanpan1.1panPan2
GBA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11152,264,959 - 52,277,298 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1152,265,070 - 52,277,213 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,832,513 - 50,844,997 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01153,329,882 - 53,342,367 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1153,329,897 - 53,342,066 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,874,428 - 51,886,910 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,857,946 - 51,870,446 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,560,096 - 52,572,581 (-)NCBIUU_Cfam_GSD_1.0
Gba2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947167,183,253 - 167,194,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365243,730,833 - 3,742,531 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365243,730,833 - 3,742,526 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GBA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,455,240 - 236,468,210 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,456,238 - 236,467,887 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21264,181,426 - 264,193,076 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GBA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11244,852,048 - 44,865,542 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1244,852,203 - 44,868,652 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603841,956,699 - 41,969,099 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gba2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248685,045,594 - 5,056,416 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248685,045,566 - 5,056,419 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gba2
309 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1304
Count of miRNA genes:509
Interacting mature miRNAs:615
Transcripts:ENSMUST00000030189, ENSMUST00000128403, ENSMUST00000130443, ENSMUST00000139606, ENSMUST00000144968, ENSMUST00000148426, ENSMUST00000152251
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
10401115Pgia35_mproteoglycan induced arthritis 35 (mouse)Not determined41256237746562509Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261688982216Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663283678Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
12880405Jcdq1_mjoint cartilage degeneration QTL 1 (mouse)41256237746562509Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763283678Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261688982216Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117072206Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
25440481Moaq1_mmodifier of alien QTL 1 (mouse)41950000046000000Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261688982216Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
4142290Ssrq9_mstress response QTL 9 (mouse)Not determined3439516046332776Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
10401905Sicd3_mseizure-induced cell death 3 (mouse)Not determined4939552543760862Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302184Aaom1_mautoimmune aoritis in MRL mice 1 (mouse)Not determined42432229946332776Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000128993793Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108357197Mouse

Markers in Region
AW538053  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,566,878 - 43,566,980UniSTSGRCm38
MGSCv37443,579,750 - 43,579,852UniSTSGRCm37
Celera443,600,867 - 43,600,969UniSTS
Cytogenetic Map4B1UniSTS
cM Map420.5UniSTS
Whitehead/MRC_RH4675.8UniSTS
C80076  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,566,690 - 43,566,787UniSTSGRCm38
MGSCv37443,579,562 - 43,579,659UniSTSGRCm37
Celera443,600,679 - 43,600,776UniSTS
Cytogenetic Map4B1UniSTS
cM Map420.5UniSTS
Whitehead/MRC_RH4674.73UniSTS
AU044960  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,566,689 - 43,566,980UniSTSGRCm38
MGSCv37443,579,561 - 43,579,852UniSTSGRCm37
Celera443,600,678 - 43,600,969UniSTS
Cytogenetic Map4B1UniSTS
cM Map420.5UniSTS
Whitehead/MRC_RH4675.8UniSTS
UniSTS:234909  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,566,518 - 43,566,729UniSTSGRCm38
MGSCv37443,579,390 - 43,579,601UniSTSGRCm37
Celera443,600,507 - 43,600,718UniSTS
Cytogenetic Map4B1UniSTS
cM Map420.5UniSTS
UniSTS:234911  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38443,567,685 - 43,567,984UniSTSGRCm38
MGSCv37443,580,557 - 43,580,856UniSTSGRCm37
Celera443,601,674 - 43,601,973UniSTS
Cytogenetic Map4B1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001425035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK089192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK173213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL732626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB869336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ709107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000030189   ⟹   ENSMUSP00000030189
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,566,928 - 43,578,873 (-)Ensembl
GRCm38.p6 Ensembl443,566,928 - 43,578,873 (-)Ensembl
Ensembl Acc Id: ENSMUST00000128403
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,566,928 - 43,578,089 (-)Ensembl
GRCm38.p6 Ensembl443,566,928 - 43,578,089 (-)Ensembl
Ensembl Acc Id: ENSMUST00000130443   ⟹   ENSMUSP00000119589
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,570,762 - 43,578,636 (-)Ensembl
GRCm38.p6 Ensembl443,570,762 - 43,578,636 (-)Ensembl
Ensembl Acc Id: ENSMUST00000139606
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,568,394 - 43,569,642 (-)Ensembl
GRCm38.p6 Ensembl443,568,394 - 43,569,642 (-)Ensembl
Ensembl Acc Id: ENSMUST00000144968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,570,356 - 43,574,054 (-)Ensembl
GRCm38.p6 Ensembl443,570,356 - 43,574,054 (-)Ensembl
Ensembl Acc Id: ENSMUST00000148426
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,566,929 - 43,578,089 (-)Ensembl
GRCm38.p6 Ensembl443,566,929 - 43,578,089 (-)Ensembl
Ensembl Acc Id: ENSMUST00000152251
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl443,566,928 - 43,578,537 (-)Ensembl
GRCm38.p6 Ensembl443,566,928 - 43,578,537 (-)Ensembl
RefSeq Acc Id: NM_001425035   ⟹   NP_001411964
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39443,566,928 - 43,578,893 (-)NCBI
RefSeq Acc Id: NM_172692   ⟹   NP_766280
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39443,566,928 - 43,578,893 (-)NCBI
GRCm38443,566,928 - 43,578,864 (-)ENTREZGENE
MGSCv37443,579,800 - 43,591,736 (-)RGD
Celera443,600,917 - 43,612,853 (-)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_766280   ⟸   NM_172692
- Peptide Label: isoform 1
- UniProtKB: Q6PGM3 (UniProtKB/Swiss-Prot),   Q8BTN9 (UniProtKB/Swiss-Prot),   Q69ZF3 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000119589   ⟸   ENSMUST00000130443
Ensembl Acc Id: ENSMUSP00000030189   ⟸   ENSMUST00000030189
RefSeq Acc Id: NP_001411964   ⟸   NM_001425035
- Peptide Label: isoform 2
Protein Domains
Glycosyl-hydrolase family 116 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q69ZF3-F1-model_v2 AlphaFold Q69ZF3 1-918 view protein structure

Promoters
RGD ID:6883236
Promoter ID:EPDNEW_M5069
Type:multiple initiation site
Name:Gba2_2
Description:Mus musculus glucosidase beta 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5070  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38443,578,551 - 43,578,611EPDNEW
RGD ID:6883238
Promoter ID:EPDNEW_M5070
Type:initiation region
Name:Gba2_1
Description:Mus musculus glucosidase beta 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5069  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38443,578,893 - 43,578,953EPDNEW
RGD ID:6835682
Promoter ID:MM_KWN:37361
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000016233,   UC008SQH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,582,376 - 43,584,172 (-)MPROMDB
RGD ID:6835357
Promoter ID:MM_KWN:37362
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Liver,   Lung
Transcripts:OTTMUST00000016231
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,586,426 - 43,587,322 (-)MPROMDB
RGD ID:6835355
Promoter ID:MM_KWN:37363
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000107888,   OTTMUST00000016147,   OTTMUST00000016148,   OTTMUST00000016149,   OTTMUST00000016232,   OTTMUST00000064236
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36443,591,199 - 43,591,699 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2654325 AgrOrtholog
Ensembl Genes ENSMUSG00000028467 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000030189 ENTREZGENE
  ENSMUST00000030189.14 UniProtKB/Swiss-Prot
  ENSMUST00000130443.2 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/Swiss-Prot
InterPro 6-hairpin_glycosidase_sf UniProtKB/Swiss-Prot
  6hp_glycosidase-like_sf UniProtKB/Swiss-Prot
  B_Glucosidase_GBA2-typ UniProtKB/Swiss-Prot
  GH116_catalytic UniProtKB/Swiss-Prot
  GH116_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Non-lysos_glucosylceramidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:230101 UniProtKB/Swiss-Prot
MGD MGI:2654325 ENTREZGENE
NCBI Gene 230101 ENTREZGENE
PANTHER BILE ACID BETA-GLUCOSIDASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NON-LYSOSOMAL GLUCOSYLCERAMIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF608 UniProtKB/Swiss-Prot
  Glyco_hydr_116N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gba2 PhenoGen
PIRSF Beta_gluc_GBA2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48208 UniProtKB/Swiss-Prot
UniProt B1AWI3_MOUSE UniProtKB/TrEMBL
  GBA2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6PGM3 ENTREZGENE
  Q8BTN9 ENTREZGENE
UniProt Secondary Q6PGM3 UniProtKB/Swiss-Prot
  Q8BTN9 UniProtKB/Swiss-Prot