Dok5 (docking protein 5) - Rat Genome Database

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Gene: Dok5 (docking protein 5) Ictidomys tridecemlineatus
Analyze
Symbol: Dok5
Name: docking protein 5
RGD ID: 12728834
Description: INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (ortholog); neuron differentiation (ortholog); positive regulation of MAPK cascade (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: docking protein 5, transcript variant X1; docking protein 5, transcript variant X2; docking protein 5, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640185,619,508 - 185,765,999 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365141,073,002 - 1,219,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365141,073,067 - 1,219,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dok5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640185,619,508 - 185,765,999 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365141,073,002 - 1,219,659 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365141,073,067 - 1,219,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DOK5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382054,475,593 - 54,651,169 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2054,475,593 - 54,651,169 (+)EnsemblGRCh38hg38GRCh38
GRCh372053,092,132 - 53,267,708 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362052,525,673 - 52,701,117 (+)NCBINCBI36Build 36hg18NCBI36
Build 342052,525,663 - 52,701,116NCBI
Celera2049,796,955 - 49,972,466 (+)NCBICelera
Cytogenetic Map20q13.2NCBI
HuRef2049,839,614 - 50,014,934 (+)NCBIHuRef
CHM1_12052,995,435 - 53,170,794 (+)NCBICHM1_1
T2T-CHM13v2.02056,249,933 - 56,425,528 (+)NCBIT2T-CHM13v2.0
Dok5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392170,573,722 - 170,721,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2170,573,727 - 170,721,689 (+)EnsemblGRCm39 Ensembl
GRCm382170,731,807 - 170,879,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2170,731,807 - 170,879,769 (+)EnsemblGRCm38mm10GRCm38
MGSCv372170,557,307 - 170,705,275 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362170,423,145 - 170,570,973 (+)NCBIMGSCv36mm8
Celera2176,688,120 - 176,839,591 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map292.26NCBI
Dok5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83179,934,419 - 180,071,334 (+)NCBIGRCr8
mRatBN7.23159,515,886 - 159,652,811 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3159,515,893 - 159,652,810 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3163,325,199 - 163,461,738 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03171,824,765 - 171,961,310 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03169,565,982 - 169,702,535 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03168,345,116 - 168,482,445 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3168,345,152 - 168,482,441 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03174,447,106 - 174,579,715 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43161,654,964 - 161,729,978 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3158,734,945 - 158,869,891 (+)NCBICelera
Cytogenetic Map3q42NCBI
Dok5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554454,438,673 - 4,601,618 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554454,439,299 - 4,601,618 (-)NCBIChiLan1.0ChiLan1.0
DOK5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22160,227,206 - 60,402,745 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12060,220,386 - 60,395,866 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02050,821,093 - 50,996,536 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12052,042,915 - 52,217,846 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2052,042,491 - 52,217,846 (+)Ensemblpanpan1.1panPan2
DOK5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12440,156,235 - 40,282,059 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2440,130,265 - 40,282,249 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2439,373,809 - 39,526,644 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02440,842,571 - 40,995,459 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2440,842,594 - 40,995,459 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12440,078,376 - 40,230,790 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02440,219,720 - 40,372,625 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02440,930,261 - 41,031,259 (+)NCBIUU_Cfam_GSD_1.0
DOK5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1755,390,802 - 55,583,858 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11755,391,074 - 55,541,561 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21762,396,656 - 62,547,368 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DOK5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.129,404,105 - 9,571,663 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl29,403,813 - 9,571,476 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605057,514,278 - 57,682,131 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dok5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247901,722,555 - 1,881,392 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247901,725,478 - 1,881,416 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000020166   ⟹   ENSSTOP00000021793
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365141,073,002 - 1,219,659 (-)Ensembl
RefSeq Acc Id: XM_005325198   ⟹   XP_005325255
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,765,881 (-)NCBI
SpeTri2.0NW_0049365141,073,067 - 1,219,340 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040274128   ⟹   XP_040130062
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,719,755 (-)NCBI
RefSeq Acc Id: XM_040274129   ⟹   XP_040130063
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,746,717 (-)NCBI
RefSeq Acc Id: XM_040274131   ⟹   XP_040130065
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,765,334 (-)NCBI
RefSeq Acc Id: XM_040274132   ⟹   XP_040130066
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,764,897 (-)NCBI
RefSeq Acc Id: XM_040274133   ⟹   XP_040130067
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640185,619,508 - 185,765,999 (-)NCBI
RefSeq Acc Id: XP_005325255   ⟸   XM_005325198
- Peptide Label: isoform X2
- UniProtKB: I3NBP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040130067   ⟸   XM_040274133
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130065   ⟸   XM_040274131
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130066   ⟸   XM_040274132
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130063   ⟸   XM_040274129
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040130062   ⟸   XM_040274128
- Peptide Label: isoform X1
Ensembl Acc Id: ENSSTOP00000021793   ⟸   ENSSTOT00000020166
Protein Domains
IRS-type PTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028767 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020166.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro Docking_Protein_DOK UniProtKB/TrEMBL
  DOK4/5/6_PH UniProtKB/TrEMBL
  IRS_PTB UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Dok5 ENTREZGENE
PANTHER DOCKING PROTEIN 5 UniProtKB/TrEMBL
  DOCKING PROTEIN RELATED UniProtKB/TrEMBL
Pfam IRS UniProtKB/TrEMBL
PROSITE IRS_PTB UniProtKB/TrEMBL
SMART IRS UniProtKB/TrEMBL
  PTBI UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt I3NBP6 ENTREZGENE, UniProtKB/TrEMBL