Ubd<sup>em1</sup> (ubiquitin D; CRISPR/Cas9 induced mutant1) - Rat Genome Database

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Gene: Ubdem1 (ubiquitin D; CRISPR/Cas9 induced mutant1) Rattus norvegicus
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Symbol: Ubdem1
Name: ubiquitin D; CRISPR/Cas9 induced mutant1
RGD ID: 126925166
Description: This Ubd knockout rat allele was generated using theCRISPR-Cas9 technique in a Sprague Dawley (SD) background. The knockout allele has a 911 bp deletion of exon 2, leading to a truncated protein of Ubd.
ASSOCIATED WITH cardiac interstitial fibrosis; decreased cardiac muscle contractility; increased cardiomyocyte apoptosis; ASSOCIATED WITH myocardial infarction
Type: allele  of Ubd  
Previously known as: Ubd^[em1]
Is Marker For: Strains:   SD-Ubdem1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. FAT10 attenuates hypoxia-induced cardiomyocyte apoptosis by stabilizing caveolin-3. Zhou Q, etal., J Mol Cell Cardiol. 2018 Mar;116:115-124. doi: 10.1016/j.yjmcc.2018.02.008. Epub 2018 Feb 10.

Genomics


Related Rat Strains
The following Strains have been annotated to Ubdem1
SD-Ubdem1    


Expression


Sequence

Nucleotide Sequences


Additional Information