Grm6 (glutamate metabotropic receptor 6) - Rat Genome Database

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Gene: Grm6 (glutamate metabotropic receptor 6) Ictidomys tridecemlineatus
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Symbol: Grm6
Name: glutamate metabotropic receptor 6
RGD ID: 12682993
Description: ENCODES a protein that exhibits adenylate cyclase inhibiting G protein-coupled glutamate receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway (ortholog); chemical synaptic transmission (ortholog); gene expression (ortholog); ASSOCIATED WITH congenital stationary night blindness (ortholog); congenital stationary night blindness 1B (ortholog); congenital stationary night blindness 1C (ortholog); FOUND IN cell tip (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate metabotropic receptor 6, transcript variant X1; glutamate metabotropic receptor 6, transcript variant X2; glutamate metabotropic receptor 6, transcript variant X3; glutamate metabotropic receptor 6, transcript variant X4; glutamate metabotropic receptor 6, transcript variant X5; glutamate metabotropic receptor 6, transcript variant X6; metabotropic glutamate receptor 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213120,517,460 - 120,533,914 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,727,808 - 1,741,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,726,382 - 1,742,937 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Grm6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213120,517,460 - 120,533,914 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367391,727,808 - 1,741,400 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367391,726,382 - 1,742,937 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRM6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385178,978,327 - 178,995,320 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5178,977,587 - 178,996,206 (-)EnsemblGRCh38hg38GRCh38
GRCh375178,405,328 - 178,422,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365178,337,934 - 178,354,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 345178,337,937 - 178,354,730NCBI
Celera5174,032,368 - 174,049,143 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5173,132,574 - 173,149,375 (-)NCBIHuRef
CHM1_15177,838,464 - 177,855,246 (-)NCBICHM1_1
T2T-CHM13v2.05179,531,590 - 179,548,578 (-)NCBIT2T-CHM13v2.0
Grm6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,741,205 - 50,757,035 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,741,512 - 50,757,035 (+)EnsemblGRCm39 Ensembl
GRCm381150,850,369 - 50,866,208 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,850,685 - 50,866,208 (+)EnsemblGRCm38mm10GRCm38
MGSCv371150,664,187 - 50,679,710 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361150,700,247 - 50,709,631 (+)NCBIMGSCv36mm8
MGSCv361151,275,794 - 51,285,178 (+)NCBIMGSCv36mm8
Celera1155,412,795 - 55,423,405 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1130.93NCBI
Grm6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81035,669,003 - 35,683,729 (+)NCBIGRCr8
mRatBN7.21035,167,985 - 35,182,717 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,167,985 - 35,182,717 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1039,850,547 - 39,865,320 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01039,340,860 - 39,355,633 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01034,844,228 - 34,859,005 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01036,345,503 - 36,363,416 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1036,345,939 - 36,360,665 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,116,940 - 36,133,439 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41036,421,806 - 36,436,909 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11036,422,854 - 36,437,992 (+)NCBI
Celera1034,527,201 - 34,541,916 (+)NCBICelera
Cytogenetic Map10q22NCBI
Grm6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554081,421,132 - 1,433,622 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554081,421,132 - 1,432,010 (+)NCBIChiLan1.0ChiLan1.0
GRM6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24173,919,371 - 173,939,175 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15172,062,606 - 172,078,715 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05174,142,754 - 174,156,294 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15181,434,031 - 181,447,341 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5181,434,031 - 181,447,341 (-)Ensemblpanpan1.1panPan2
GRM6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1112,577,988 - 2,598,893 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl112,577,988 - 2,597,575 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha112,701,951 - 2,723,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0112,554,140 - 2,575,871 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl112,554,140 - 2,573,733 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1112,525,443 - 2,547,158 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0112,603,862 - 2,625,566 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0112,844,699 - 2,866,420 (+)NCBIUU_Cfam_GSD_1.0
GRM6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl279,466,779 - 79,479,146 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1279,466,899 - 79,480,562 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2281,070,972 - 81,085,309 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRM6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12380,732,687 - 80,747,389 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2380,733,486 - 80,746,708 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607512,088,339 - 12,101,526 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grm6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473341,987,319 - 41,997,541 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473341,984,632 - 41,997,726 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000022460   ⟹   ENSSTOP00000023229
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367391,727,808 - 1,741,400 (+)Ensembl
RefSeq Acc Id: XM_005339349   ⟹   XP_005339406
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,470 - 120,533,914 (+)NCBI
SpeTri2.0NW_0049367391,727,230 - 1,742,937 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021735967   ⟹   XP_021591642
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,468 - 120,533,914 (+)NCBI
SpeTri2.0NW_0049367391,727,229 - 1,742,937 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021735971   ⟹   XP_021591646
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,467 - 120,533,914 (+)NCBI
SpeTri2.0NW_0049367391,727,229 - 1,742,937 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021735972   ⟹   XP_021591647
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,518,385 - 120,533,914 (+)NCBI
SpeTri2.0NW_0049367391,728,218 - 1,742,937 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040272081   ⟹   XP_040128015
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,468 - 120,533,914 (+)NCBI
RefSeq Acc Id: XM_040272082   ⟹   XP_040128016
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,470 - 120,533,914 (+)NCBI
RefSeq Acc Id: XM_040272083   ⟹   XP_040128017
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213120,517,460 - 120,527,056 (+)NCBI
RefSeq Acc Id: XP_005339406   ⟸   XM_005339349
- Peptide Label: isoform X2
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591642   ⟸   XM_021735967
- Peptide Label: isoform X1
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591646   ⟸   XM_021735971
- Peptide Label: isoform X3
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021591647   ⟸   XM_021735972
- Peptide Label: isoform X6
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040128017   ⟸   XM_040272083
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040128015   ⟸   XM_040272081
- Peptide Label: isoform X4
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040128016   ⟸   XM_040272082
- Peptide Label: isoform X5
- UniProtKB: I3NFT2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000023229   ⟸   ENSSTOT00000022460
Protein Domains
G-protein coupled receptors family 3 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000021282 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000022460.2 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_CS UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt_6 UniProtKB/TrEMBL
  mGluR UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Grm6 ENTREZGENE
PANTHER METABOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
  METABOTROPIC GLUTAMATE RECEPTOR 6 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PRINTS GPCRMGR UniProtKB/TrEMBL
  MTABOTROPC6R UniProtKB/TrEMBL
  MTABOTROPICR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt I3NFT2 ENTREZGENE, UniProtKB/TrEMBL