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Gene: GRM6 (glutamate metabotropic receptor 6) Homo sapiens
Symbol: GRM6
Name: glutamate metabotropic receptor 6
Description: Exhibits glutamate receptor activity and protein homodimerization activity. Involved in G protein-coupled glutamate receptor signaling pathway; detection of light stimulus involved in visual perception; and positive regulation of calcium ion import. Localizes to the Golgi membrane; endoplasmic reticulum membrane; and integral component of plasma membrane. Implicated in congenital stationary night blindness 1B.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CSNB1B; DKFZp686H1993; glutamate receptor, metabotropic 6; GPRC1F; metabotropic glutamate receptor 6; mGlu6; MGLUR6
Mus musculus (house mouse) : Grm6 (glutamate receptor, metabotropic 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Grm6 (glutamate metabotropic receptor 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grm6 (glutamate metabotropic receptor 6)
Pan paniscus (bonobo/pygmy chimpanzee) : GRM6 (glutamate metabotropic receptor 6)
Canis lupus familiaris (dog) : GRM6 (glutamate metabotropic receptor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grm6 (glutamate metabotropic receptor 6)
Sus scrofa (pig) : GRM6 (glutamate metabotropic receptor 6)
Chlorocebus sabaeus (green monkey) : GRM6 (glutamate metabotropic receptor 6)
Heterocephalus glaber (naked mole-rat) : Grm6 (glutamate metabotropic receptor 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl5178,977,587 - 178,996,206 (-)Ensembl
GRCh385178,978,327 - 178,995,320 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375178,405,328 - 178,422,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365178,337,934 - 178,354,730 (-)NCBINCBI36hg18NCBI36
Build 345178,337,937 - 178,354,730NCBI
Celera5174,032,368 - 174,049,143 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5173,132,574 - 173,149,375 (-)NCBIHuRef
CHM1_15177,838,464 - 177,855,246 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GRM6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70075
Created: 2002-01-22
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.