Tspoap1 (TSPO associated protein 1) - Rat Genome Database

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Gene: Tspoap1 (TSPO associated protein 1) Ictidomys tridecemlineatus
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Symbol: Tspoap1
Name: TSPO associated protein 1
RGD ID: 12676649
Description: ENCODES a protein that exhibits benzodiazepine receptor binding (inferred); voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (inferred); INVOLVED IN regulation of neurotransmitter secretion (inferred); regulation of presynaptic cytosolic calcium ion concentration (inferred); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); COVID-19 (ortholog); dystonia (ortholog); FOUND IN calyx of Held (inferred); cytoplasm (inferred); glutamatergic synapse (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: benzodiazapine receptor (peripheral) associated protein 1; peripheral-type benzodiazepine receptor-associated protein 1; TSPO associated protein 1, transcript variant X1; TSPO associated protein 1, transcript variant X2; TSPO associated protein 1, transcript variant X3; TSPO associated protein 1, transcript variant X4; TSPO associated protein 1, transcript variant X5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,281,872 - 32,308,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,766,521 - 4,793,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,766,564 - 4,793,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tspoap1SquirrelCOVID-19  ISOTSPOAP1 (Homo sapiens)9068941mRNA:decreased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tspoap1SquirrelBardet-Biedl syndrome  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Bardet-Biedl syndromeClinVarPMID:25741868
Tspoap1Squirreldystonia  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: TSPOAP1-related DystoniaClinVar 
Tspoap1Squirreldystonia 22, adult-onset  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Dystonia 22 and adult-onsetClinVarPMID:25741868 and PMID:33539324
Tspoap1Squirreldystonia 22, juvenile-onset  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Dystonia 22 and juvenile-onsetClinVarPMID:33539324
Tspoap1Squirrelhereditary breast ovarian cancer syndrome  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Breast-ovarian cancer more ...ClinVarPMID:38922859
Tspoap1Squirrelintellectual disability  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868 more ...
Tspoap1SquirrelJoubert syndrome 1  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Familial aplasia of the vermisClinVarPMID:28492532
Tspoap1SquirrelNeurodevelopmental Disorders  ISOTSPOAP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868 and PMID:33539324
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tspoap1Squirreldystonia 22, adult-onset  ISOTSPOAP1 (Homo sapiens)7240710 OMIM 
Tspoap1Squirreldystonia 22, juvenile-onset  ISOTSPOAP1 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tspoap1Squirrelregulation of neurotransmitter secretion involved_inIEAUniProtKB:O95153 and ensembl:ENSP00000345824150520179 EnsemblGO_REF:0000107
Tspoap1Squirrelregulation of presynaptic cytosolic calcium ion concentration involved_inIEAGO:0099626150520179 GOCGO_REF:0000108

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Tspoap1Squirrelcalyx of Held is_active_inIEAUniProtKB:Q7TNF8 and ensembl:ENSMUSP00000048063150520179 EnsemblGO_REF:0000107
Tspoap1Squirrelcytoplasm located_inIEAUniProtKB:O95153 and ensembl:ENSP00000345824150520179 EnsemblGO_REF:0000107
Tspoap1Squirrelglutamatergic synapse is_active_inIEAUniProtKB:Q7TNF8 and ensembl:ENSMUSP00000048063150520179 EnsemblGO_REF:0000107
Tspoap1Squirrelmitochondrion located_inIEAUniProtKB:O95153 and ensembl:ENSP00000345824150520179 EnsemblGO_REF:0000107
Tspoap1Squirrelmitochondrion located_inIEAPANTHER:PTN000369473150520179 TreeGrafterGO_REF:0000118

Molecular Function

  

PMID:22301074   PMID:30032202  



Tspoap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560232,281,872 - 32,308,501 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364904,766,521 - 4,793,361 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364904,766,564 - 4,793,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TSPOAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381758,301,231 - 58,328,795 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1758,301,228 - 58,328,795 (-)EnsemblGRCh38hg38GRCh38
GRCh371756,378,592 - 56,406,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361753,733,591 - 53,760,477 (-)NCBINCBI36Build 36hg18NCBI36
Build 341753,733,594 - 53,760,477NCBI
Celera1752,840,368 - 52,867,932 (-)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1751,739,174 - 51,766,689 (-)NCBIHuRef
CHM1_11756,443,607 - 56,471,171 (-)NCBICHM1_1
T2T-CHM13v2.01759,169,111 - 59,196,675 (-)NCBIT2T-CHM13v2.0
Tspoap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391187,649,022 - 87,676,754 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1187,651,367 - 87,676,754 (+)EnsemblGRCm39 Ensembl
GRCm381187,758,194 - 87,785,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1187,760,541 - 87,785,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,574,043 - 87,599,430 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,593,288 - 87,602,113 (+)NCBIMGSCv36mm8
Celera1197,356,384 - 97,381,737 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1152.21NCBI
Tspoap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81073,053,414 - 73,083,640 (+)NCBIGRCr8
mRatBN7.21072,554,220 - 72,586,402 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1072,560,980 - 72,586,412 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01075,053,956 - 75,079,615 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1075,055,020 - 75,076,434 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01075,022,773 - 75,048,322 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,053,461 - 76,074,635 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11076,067,993 - 76,091,091 (+)NCBI
Celera1071,474,298 - 71,499,715 (+)NCBICelera
Cytogenetic Map10q26NCBI
Tspoap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554514,707,458 - 4,730,257 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554514,707,440 - 4,733,179 (+)NCBIChiLan1.0ChiLan1.0
TSPOAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21974,472,465 - 74,499,871 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11779,283,639 - 79,311,079 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01752,376,707 - 52,404,160 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11757,232,244 - 57,259,669 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1757,232,244 - 57,259,669 (-)Ensemblpanpan1.1panPan2
TSPOAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1932,949,912 - 32,972,830 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl932,950,906 - 32,973,982 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha932,186,983 - 32,211,808 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0933,756,622 - 33,781,455 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl933,756,622 - 33,780,594 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1932,542,761 - 32,567,618 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0932,826,233 - 32,851,116 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0932,919,705 - 32,944,540 (-)NCBIUU_Cfam_GSD_1.0
TSPOAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1234,578,704 - 34,605,888 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11234,578,698 - 34,606,623 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21236,206,776 - 36,234,699 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TSPOAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11635,071,519 - 35,099,174 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1635,072,385 - 35,096,057 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660775,886,290 - 5,914,097 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tspoap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624871140,612 - 165,411 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624871139,513 - 165,564 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSSTOT00000020180   ⟹   ENSSTOP00000021805
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364904,767,435 - 4,790,270 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000033918   ⟹   ENSSTOP00000030141
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364904,766,521 - 4,793,361 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000040121   ⟹   ENSSTOP00000030304
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364904,766,521 - 4,793,361 (+)Ensembl
RefSeq Acc Id: XM_005321582   ⟹   XP_005321639
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,282,902 - 32,308,500 (-)NCBI
SpeTri2.0NW_0049364904,766,564 - 4,793,174 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021724086   ⟹   XP_021579761
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,281,872 - 32,308,501 (-)NCBI
SpeTri2.0NW_0049364904,766,564 - 4,793,174 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040269030   ⟹   XP_040124964
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,281,872 - 32,308,501 (-)NCBI
RefSeq Acc Id: XM_040269031   ⟹   XP_040124965
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,281,872 - 32,308,501 (-)NCBI
RefSeq Acc Id: XM_040269032   ⟹   XP_040124966
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,281,872 - 32,308,500 (-)NCBI
RefSeq Acc Id: XM_040269033   ⟹   XP_040124967
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560232,281,872 - 32,308,500 (-)NCBI
RefSeq Acc Id: XP_005321639   ⟸   XM_005321582
- Peptide Label: isoform X4
- UniProtKB: A0A287D9F9 (UniProtKB/TrEMBL),   I3NBQ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579761   ⟸   XM_021724086
- Peptide Label: isoform X1
- UniProtKB: A0A287D9T9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040124965   ⟸   XM_040269031
- Peptide Label: isoform X3
- UniProtKB: A0A287D9T9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040124964   ⟸   XM_040269030
- Peptide Label: isoform X2
- UniProtKB: A0A287D9T9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040124967   ⟸   XM_040269033
- Peptide Label: isoform X6
- UniProtKB: A0A287D9T9 (UniProtKB/TrEMBL)
Fibronectin type-III   SH3



1 to 28 of 28 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSSTOG00000023162 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020180.2 UniProtKB/TrEMBL
  ENSSTOT00000033918.1 UniProtKB/TrEMBL
  ENSSTOT00000040121.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  RIM-BP_SH3_2 UniProtKB/TrEMBL
  RIM-BP_SH3_3 UniProtKB/TrEMBL
  RIMBP1/2/3 UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene Tspoap1 ENTREZGENE
PANTHER PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1 UniProtKB/TrEMBL
  PTHR14234 UniProtKB/TrEMBL
Pfam SH3_2 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A287D9F9 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D9T9 ENTREZGENE, UniProtKB/TrEMBL
  I3NBQ8 ENTREZGENE, UniProtKB/TrEMBL
1 to 28 of 28 rows