Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19)

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Gene: Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19) Ictidomys tridecemlineatus

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Symbol:

Dnajc19

Name:

DnaJ heat shock protein family (Hsp40) member C19

RGD ID:

12650518

Description:

ENCODES a protein that exhibits ATPase activator activity (inferred); INVOLVED IN regulation of cardiolipin metabolic process (ortholog); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH 3-methylglutaconic aciduria (ortholog); 3-methylglutaconic aciduria type 3 (ortholog); 3-methylglutaconic aciduria type 5 (ortholog); FOUND IN inner mitochondrial membrane protein complex (ortholog); matrix side of mitochondrial inner membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mitochondrial import inner membrane translocase subunit TIM14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	110,872,579 - 110,877,731 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936566	2,343,013 - 2,368,213 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936566	2,342,995 - 2,348,345 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

3-methylglutaconic aciduria (ISO)

3-methylglutaconic aciduria type 3 (ISO)

3-methylglutaconic aciduria type 5 (ISO)

Currarino syndrome (ISO)

genetic disease (ISO)

syndromic microphthalmia 3 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

genitalia development (IEA)

protein import into mitochondrial matrix (IEA)

protein transport (IEA)

regulation of cardiolipin metabolic process (ISO)

visual perception (IEA)

Cellular Component

inner mitochondrial membrane protein complex (ISO)

matrix side of mitochondrial inner membrane (ISO)

mitochondrial inner membrane (IEA)

mitochondrion (IEA)

PAM complex, Tim23 associated import motor (IEA)

protein-containing complex (IEA)

Molecular Function

ATPase activator activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

presequence pathway of mitochondrial protein import (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Dnajc19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	110,872,579 - 110,877,731 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936566	2,343,013 - 2,368,213 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936566	2,342,995 - 2,348,345 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJC19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	180,983,709 - 180,989,838 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	180,983,697 - 180,989,774 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	180,701,497 - 180,707,626 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	182,184,197 - 182,190,224 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	179,133,934 - 179,140,000 (-)	NCBI		Celera
Cytogenetic Map	3	q26.33	NCBI
HuRef	3	178,105,493 - 178,111,557 (-)	NCBI		HuRef
CHM1_1	3	180,664,781 - 180,670,846 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	183,785,491 - 183,791,620 (-)	NCBI		T2T-CHM13v2.0

Dnajc19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	34,111,429 - 34,135,503 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	34,110,169 - 34,135,470 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	34,057,280 - 34,081,354 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	34,056,020 - 34,081,321 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	33,956,680 - 33,980,248 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	34,249,307 - 34,272,875 (-)	NCBI		MGSCv36	mm8
Celera	3	33,953,924 - 33,977,453 (-)	NCBI		Celera
Cytogenetic Map	3	A3	NCBI
cM Map	3	16.43	NCBI

Dnajc19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	118,851,497 - 118,875,813 (-)	NCBI		GRCr8
mRatBN7.2	2	116,923,272 - 116,945,312 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	116,923,272 - 116,945,264 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	123,512,875 - 123,534,874 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	121,625,542 - 121,647,543 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	116,253,290 - 116,275,296 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	120,503,093 - 120,531,782 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	120,504,130 - 120,531,782 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	140,149,956 - 140,174,575 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	2	111,962,564 - 111,984,600 (-)	NCBI		Celera
Cytogenetic Map	2	q24	NCBI

Dnajc19
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955420	9,953,045 - 9,978,789 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955420	9,974,466 - 9,978,789 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAJC19
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	178,855,625 - 178,861,633 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	178,860,342 - 178,866,350 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	178,019,161 - 178,025,272 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	186,191,128 - 186,197,156 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	186,191,128 - 186,195,666 (-)	Ensembl	panpan1.1		panPan2

DNAJC19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	14,199,507 - 14,204,736 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	14,199,675 - 14,204,687 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	18,281,677 - 18,286,739 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	14,101,051 - 14,106,123 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	14,098,572 - 14,106,041 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	14,146,876 - 14,151,940 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	14,129,181 - 14,134,245 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	14,373,244 - 14,378,316 (-)	NCBI		UU_Cfam_GSD_1.0

DNAJC19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	118,902,666 - 118,913,270 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	118,907,299 - 118,913,270 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	128,168,301 - 128,255,013 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJC19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	8,408,615 - 8,426,838 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	8,408,400 - 8,429,990 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666063	17,240,292 - 17,259,188 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajc19
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	58,730,413 - 58,755,688 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	58,746,824 - 58,755,544 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005330258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000011508 ⟹ ENSSTOP00000010329

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936566	2,344,139 - 2,368,213 (+)	Ensembl

Ensembl Acc Id:

ENSSTOT00000031639 ⟹ ENSSTOP00000032093

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936566	2,343,013 - 2,346,891 (+)	Ensembl

RefSeq Acc Id:

XM_005330258 ⟹ XP_005330315

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	110,872,579 - 110,877,731 (-)	NCBI
SpeTri2.0	NW_004936566	2,342,995 - 2,348,345 (+)	NCBI

Sequence:

show sequence

TTCCGACCTAGTTGGCGGCCGCTACTGCCGTATTTCACAGGGCTTCTGGACTTGAGAACTTGAG
GTTGCTTCGGTGATTGCGTCTCTTTCGGGTAAAGGCTTATGGTGGTGACCTTGTCTTCTGGACT
GGGATGAACCGCGCTCCTGGTGGAAGCAGGGAAGCCGAGCTGAGCCATGGCCAGTACAGTGGTA
GCAGTTGGACTGACCATTGCTGCTGCAGGATTTGCAGGCCGTTATGTTTTACAAGCCATGAAGC
ACATGGAGCCTCAAGTAAAACAAGTTTTTCAAAGTCTACCAAAATCTGCCTTCAGTGGTGGCTA
CTACAGAGGTGGGTTTGAAACCAAAATGACAAAACGGGAAGCAGCATTAATACTAGGTGTAAGC
CCTACAGCCAATAAAGCAAAAATTAGAGATGCTCATCGACGAATTATGCTTTTAAATCACCCAG
ATAAAGGAGGATCTCCTTACATAGCAGCCAAAATCAATGAAGCTAAAGATTTATTAGAAGGTCA
AGCTAAAAAATGAAGTAAATGTATGATGGATTTTACGCTCATTAATTTATGTATATGAGTACTG
ATTTTTTTTTATAATAAAACTCCTCAGAGCTCCAATTTTTAAAAAATGATTAACCACAAGCTAA
AATAAAAGCCTTGGTATAATTTCAAATTTGAGGATTTTTAAAATCAGACTACAGTGTTTACAGA
TTAATATTCAATAATTACAGAAAGATACATGTGATGTTAGGAGAAACATTATTATTCATTACTC
ATTTATTATTTGCACATATGGTGCCCATATGTGCTCTTAAGGCACAGTTCTTGCTCTAAAACAG
CCAGTCTAATGGGGGACTAAAATATTATGGAGTTGCACACAAACTGTTGAAGCAGGTAATTCTT
ACTACCTTTGAGGAAAAACTACTCAAGATACTACTGGCCTACTTGAATTCTTAATTTAGCCACA
GCTCTGACCTAAGAAATGTCCTAGGTATGTAAAACTATGAAAATATGAAAGATTTCTGAGTACA
GGTTTGTTTTTAATCAGAATTATTTATACAGTATACAGCTAGTTTCTTAAAGACATACTGACCA
TTGATCAATTATCCCTTTTCTTTTTTACATAATCCAGATTTTTTATATTTATAATCAAGTTTAA
ACATCATTAGTGAAAATGAAATTCACTCAAGTGTCAAAATATTGTAGGTCTTGGACTATTTAGA
ATTTATACACTAATTTCAATGACATTTCACGGCAGACATTTAACAGTCTGACAAAATATGAAAG
GGTCTTAACCCGTATAAAACATCTATAGTAAACTAGCCAGTGATCCTCAATAATTTCTATCTAA
ATTTACCAAAGTCATTGTAAAGTTCTTTAATGTAGAAGACAAAGGTTTTGAGGGTGACAATTGG
GACAGTAACCAAATTTAGTGCTGAAATAGCTCTTTGGTTCACTTTCCTCCCTGTATCCTTATCT
GATGAAATCTGTAGGTTATAAGGAGGAACTGGCTTCTAAGGCTTTGTGTCAAAGGGTGGGGGTG
GGGATAAAGATACTTTCAGTCCTTTTGTATTCACAGCACTTGCATTCTTTTAAGTCATTGTGAA
CATAATTACTAAACTCTAAACCATTTGTTACTAGGGGAAATACAGGCTCCTTTTAAAGTCTCTG
GTCATATTACACAAACCGATCAATACATAAACTTGTTTTATTTATGTTTCTATTTCAAGACACC
CTATTTTCTATTTTTGCTTTATTAATATTGAACTCACTCAATGGCACTATATAACTCACTTGGC
ATATGATAGCCTTTTTTTGCTTTTAGGAAAACTAGATAAGGCTTCACTGCTATGGTTGTGAGCC
ATCTTAGAGAAATCACCAAAAACAATAAAAAAAAAAAAAACACACCCACAAAGTATGAGAGCTG
AAAAAAGTATGCACAAGACTGCCTTGTTTCAATGCATGATGTAATTCCGTTTTTTGCCACTCTG
CAAATGTTCAAAAATGACAAAGTCACAGATATATTGATTTAGAAGTTATAAATTTCAGTGAGTA
TGTGAATTCACAAATAAGGAATCCACTAATAAAGAAGACTGGCTGTGT

hide sequence

Protein Sequences


Protein RefSeqs	XP_005330315	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010329.3
	ENSSTOP00000032093.1
GenBank Protein	KAG3271058	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005330315 ⟸ XM_005330258
- UniProtKB:	A0A287DEW9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASTVVAVGLTIAAAGFAGRYVLQAMKHMEPQVKQVFQSLPKSAFSGGYYRGGFETKMTKREAA LILGVSPTANKAKIRDAHRRIMLLNHPDKGGSPYIAAKINEAKDLLEGQAKK hide sequence

Ensembl Acc Id:

ENSSTOP00000032093 ⟸ ENSSTOT00000031639

Ensembl Acc Id:

ENSSTOP00000010329 ⟸ ENSSTOT00000011508

Protein Domains

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011508	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011508.3	UniProtKB/TrEMBL
	ENSSTOT00000031639.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
InterPro	DnaJ_domain	UniProtKB/TrEMBL
	J_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Dnajc19	ENTREZGENE
PANTHER	MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM14	UniProtKB/TrEMBL
	UNCHARACTERIZED	UniProtKB/TrEMBL
Pfam	DnaJ	UniProtKB/TrEMBL
PROSITE	DNAJ_2	UniProtKB/TrEMBL
SMART	DnaJ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46565	UniProtKB/TrEMBL
UniProt	A0A287DEW9	ENTREZGENE, UniProtKB/TrEMBL
	I3MHH0_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

RGD Manual Annotations