Actbl2 (actin beta like 2) - Rat Genome Database

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Gene: Actbl2 (actin beta like 2) Ictidomys tridecemlineatus
Analyze
Symbol: Actbl2
Name: actin beta like 2
RGD ID: 12626041
Description: ENCODES a protein that exhibits identical protein binding (inferred); profilin binding (inferred); structural constituent of cytoskeleton (inferred); INVOLVED IN angiogenesis (inferred); cellular response to type II interferon (inferred); morphogenesis of a polarized epithelium (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: actin, beta like 2; actin, beta like 2, transcript variant X1; actin, beta like 2, transcript variant X2; beta-actin-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213201,588,190 - 201,589,526 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648010,524,713 - 10,526,021 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Actbl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213201,588,190 - 201,589,526 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648010,524,713 - 10,526,021 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTBL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38557,480,018 - 57,482,811 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl557,480,018 - 57,482,811 (-)EnsemblGRCh38hg38GRCh38
GRCh37556,775,845 - 56,778,638 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36556,811,600 - 56,814,393 (-)NCBINCBI36Build 36hg18NCBI36
Celera553,730,699 - 53,733,492 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef553,748,325 - 53,751,118 (-)NCBIHuRef
CHM1_1556,778,917 - 56,781,710 (-)NCBICHM1_1
T2T-CHM13v2.0558,308,736 - 58,311,529 (-)NCBIT2T-CHM13v2.0
Actbl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913111,391,547 - 111,394,283 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13111,391,547 - 111,394,283 (+)EnsemblGRCm39 Ensembl
GRCm3813111,255,013 - 111,257,749 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13111,255,013 - 111,257,749 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713112,045,221 - 112,047,957 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613112,375,891 - 112,378,627 (+)NCBIMGSCv36mm8
Celera13115,574,358 - 115,577,094 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.1NCBI
Actbl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8244,591,391 - 44,594,138 (+)NCBIGRCr8
mRatBN7.2242,858,020 - 42,860,767 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl242,858,020 - 42,860,767 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx249,977,431 - 49,980,178 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0248,035,889 - 48,038,636 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0242,887,407 - 42,890,154 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0242,829,413 - 42,832,160 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl242,829,413 - 42,832,160 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0261,878,230 - 61,880,977 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4242,585,717 - 42,588,464 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1242,506,171 - 42,507,348 (+)NCBI
Celera238,649,115 - 38,651,862 (+)NCBICelera
Cytogenetic Map2q14NCBI
Actbl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544610,508,647 - 10,509,777 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544610,508,647 - 10,509,777 (+)NCBIChiLan1.0ChiLan1.0
ACTBL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2456,437,557 - 56,440,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1554,591,187 - 54,593,979 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0556,526,042 - 56,528,831 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1558,159,900 - 58,162,687 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl558,159,996 - 58,161,126 (+)Ensemblpanpan1.1panPan2
ACTBL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1244,514,024 - 44,516,013 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl244,514,783 - 44,515,913 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha241,582,216 - 41,583,346 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0244,997,565 - 44,998,695 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl244,997,565 - 44,998,695 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1242,072,130 - 42,073,260 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0242,876,556 - 42,877,686 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,696,528 - 43,697,658 (-)NCBIUU_Cfam_GSD_1.0
ACTBL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1636,470,503 - 36,471,739 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11636,469,062 - 36,471,776 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21638,870,299 - 38,871,272 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACTBL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1453,702,645 - 53,710,029 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660492,610,195 - 2,612,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actbl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247591,787,161 - 1,788,634 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_005319606   ⟹   XP_005319663
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213201,588,190 - 201,589,526 (+)NCBI
SpeTri2.0NW_00493648010,524,713 - 10,526,021 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005319607   ⟹   XP_005319664
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213201,588,190 - 201,589,489 (+)NCBI
SpeTri2.0NW_00493648010,524,716 - 10,525,846 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005319663 (Get FASTA)   NCBI Sequence Viewer  
  XP_005319664 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006131.3
  ENSSTOP00000032263.1
GenBank Protein KAG3266655 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266656 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005319663   ⟸   XM_005319606
- Peptide Label: isoform X1
- UniProtKB: I3M8N5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005319664   ⟸   XM_005319607
- Peptide Label: isoform X2
- UniProtKB: A0A287DFD1 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006868 UniProtKB/TrEMBL
  ENSSTOG00000014797 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006858.3 UniProtKB/TrEMBL
  ENSSTOT00000039314.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.40 UniProtKB/TrEMBL
InterPro Actin UniProtKB/TrEMBL
  Actin/actin-like_CS UniProtKB/TrEMBL
  Actin_CS UniProtKB/TrEMBL
  ATPase_NBD UniProtKB/TrEMBL
NCBI Gene Actbl2 ENTREZGENE
PANTHER ACTIN UniProtKB/TrEMBL
  ACTIN, CYTOPLASMIC 2 UniProtKB/TrEMBL
  ACTIN-42A-RELATED UniProtKB/TrEMBL
Pfam Actin UniProtKB/TrEMBL
PRINTS ACTIN UniProtKB/TrEMBL
PROSITE ACTINS_1 UniProtKB/TrEMBL
  ACTINS_2 UniProtKB/TrEMBL
  ACTINS_ACT_LIKE UniProtKB/TrEMBL
SMART ACTIN UniProtKB/TrEMBL
Superfamily-SCOP Actin-like ATPase domain UniProtKB/TrEMBL
UniProt A0A287DFD1 ENTREZGENE, UniProtKB/TrEMBL
  I3M8N5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 Actbl2  actin beta like 2    actin, beta like 2  Symbol and/or name change 5135510 APPROVED