Tm2d3 (TM2 domain containing 3) - Rat Genome Database

Name: Tm2d3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Tm2d3 (TM2 domain containing 3) Ictidomys tridecemlineatus

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Symbol:

Tm2d3

Name:

TM2 domain containing 3

RGD ID:

12592196

Description:

INVOLVED IN lateral inhibition (inferred); ASSOCIATED WITH frontotemporal dementia (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

TM2 domain containing 3, transcript variant X1; TM2 domain containing 3, transcript variant X2; TM2 domain-containing protein 3

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TM2D3 (TM2 domain containing 3)	NCBI	Ortholog
Mus musculus (house mouse):	Tm2d3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tm2d3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tm2d3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TM2D3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TM2D3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TM2D3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TM2D3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tm2d3 (TM2 domain containing 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	144,114,733 - 144,123,558 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	2,210,913 - 2,220,399 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	2,210,949 - 2,219,345 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

frontotemporal dementia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

lateral inhibition (IEA)

Cellular Component

membrane (IEA)

References

Genomics

Comparative Map Data

Tm2d3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	144,114,733 - 144,123,558 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	2,210,913 - 2,220,399 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	2,210,949 - 2,219,345 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TM2D3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	101,632,977 - 101,652,381 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	101,621,444 - 101,652,391 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	102,173,180 - 102,192,584 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	99,999,572 - 100,010,117 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	78,595,626 - 78,606,219 (-)	NCBI		Celera
Cytogenetic Map	15	q26.3	NCBI
HuRef	15	78,305,847 - 78,316,388 (-)	NCBI		HuRef
CHM1_1	15	102,023,180 - 102,033,724 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	15	99,378,569 - 99,410,385 (-)	NCBI		T2T-CHM13v2.0

Tm2d3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	65,343,204 - 65,351,650 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	65,340,917 - 65,351,661 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	65,693,417 - 65,701,913 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	65,691,169 - 65,701,913 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	72,838,303 - 72,846,799 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	65,570,121 - 65,580,857 (+)	NCBI		MGSCv36	mm8
Celera	7	63,106,694 - 63,115,960 (+)	NCBI		Celera
Cytogenetic Map	7	C	NCBI
cM Map	7	35.26	NCBI

Tm2d3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	128,677,680 - 128,687,580 (+)	NCBI		GRCr8
mRatBN7.2	1	119,267,194 - 119,277,094 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	119,264,576 - 119,277,099 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	127,253,172 - 127,265,719 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	134,424,597 - 134,437,146 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	127,238,468 - 127,250,985 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	126,573,474 - 126,595,778 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	126,586,543 - 126,595,603 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	127,666,050 - 127,679,269 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	120,102,507 - 120,117,091 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	111,480,377 - 111,492,584 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Tm2d3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	28,499,634 - 28,507,867 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	28,499,077 - 28,507,907 (-)	NCBI	ChiLan1.0	ChiLan1.0

TM2D3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	91,237,996 - 91,259,824 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	94,923,661 - 94,958,955 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	80,357,201 - 80,392,500 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	99,655,558 - 99,666,052 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	99,647,402 - 99,666,445 (-)	Ensembl	panpan1.1		panPan2

TM2D3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	39,421,763 - 39,434,014 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	39,421,549 - 39,511,268 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	42,112,514 - 42,124,783 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	39,813,890 - 39,826,164 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	39,813,684 - 39,832,756 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	39,347,671 - 39,359,930 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	39,584,388 - 39,596,648 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	39,785,917 - 39,798,199 (+)	NCBI		UU_Cfam_GSD_1.0

TM2D3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	145,359,731 - 145,384,212 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	145,359,693 - 145,371,218 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	311,079,780 - 311,091,270 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TM2D3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	20,094,911 - 20,104,639 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	20,094,275 - 20,104,642 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	26,435,092 - 26,445,250 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tm2d3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	3,184,107 - 3,191,980 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624768	3,184,034 - 3,210,477 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005320073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005320075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000009087 ⟹ ENSSTOP00000008147

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936483	2,210,913 - 2,220,399 (+)	Ensembl

RefSeq Acc Id:

XM_005320073 ⟹ XP_005320130

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	144,114,733 - 144,123,558 (-)	NCBI
SpeTri2.0	NW_004936483	2,210,949 - 2,219,345 (+)	NCBI

Sequence:

show sequence

CCCCGCCTCCCGGCCCGGAAGTGCGCGCGCGCCGGCAAGATGGCAGCTGCGGCGGGACCGCTCC
AGCGCCTCCGCCGCTTGTGTCGCGTGCTGCTCTTCCTCTCGCAGTTCTACATTCTATCTGGTGG
TGGATCCTTAAATTTAGAGCATTCGCAGCCGCTGGCTCAGGCAATAAAGGATCCGGGCCCAACA
CGTACATTCACAGTAGTTCCCAGGGCAGCAGAAAGTACCGAAATCCCACCCTATATGATGAAGT
GTCCAAGCAATGGTTTATGTAGCAGACTTCCTGCAGACTGTATAGACTGTGCTACAAATTTCTC
CTGTGTCTATGGGAAGCCTGTCACTTTTGACTGTACAGTGAAACCTTCTGTTACATGTGTTGAT
CAAGATTTCAAATCCCAAAAGAGCTTTATCATCAACATGACTTGCAGATTTTGCTGGCAGCTTC
CTGAAACAGATTATGAGTGCTCCAATTCCACCAGCTGCATGACAGTGTCCTGTCCTCGGCAACG
TTACACTGCCAACTGCACGGTGCGGGATCACATCCATTGCTTGGGTAATCGTACTTTTCCCAAA
ATGCTATACTGTAATTGGACTGGAGGTTATAAGTGGTCGACTGCTCTGGCTCTAAGCATCACAC
TAGGTGGGTTTGGAGCAGACCGCTTCTACTTGGGCCAGTGGCGTGAAGGCCTGGGCAAGCTCTT
CAGCTTTGGTGGCCTGGGAATATGGACACTAATAGATGTCTTGCTAATTGGAGTTGGCTACGTG
GGACCAGCAGATGGCTCTTTGTACATTTAGCTGTGGTTATGTGCTTCAGAGAGGAGCAGTCCTT
AGGAAAAGGTCTATTGGCCTATAGTAACTGATGTGTTGTGAGTTGTGTGTTTGTATGTTTTTAA
TGTACAGCATCTGTACTTTGCTTGCCTTGATAAAGGTAAAATAAAGAAGTTAAACACTGAA

hide sequence

RefSeq Acc Id:

XM_005320075 ⟹ XP_005320132

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	144,114,733 - 144,123,556 (-)	NCBI
SpeTri2.0	NW_004936483	2,210,949 - 2,219,345 (+)	NCBI

Sequence:

show sequence

CCCCGCCTCCCGGCCCGGAAGTGCGCGCGCGCCGGCAAGATGGCAGCTGCGGCGGGACCGCTCC
AGCGCCTCCGCCGCTTGTGTCGCGTGCTGCTCTTCCTCTCGCAGTTCTACATTCTATCTGGTGG
TGAAAGTACCGAAATCCCACCCTATATGATGAAGTGTCCAAGCAATGGTTTATGTAGCAGACTT
CCTGCAGACTGTATAGACTGTGCTACAAATTTCTCCTGTGTCTATGGGAAGCCTGTCACTTTTG
ACTGTACAGTGAAACCTTCTGTTACATGTGTTGATCAAGATTTCAAATCCCAAAAGAGCTTTAT
CATCAACATGACTTGCAGATTTTGCTGGCAGCTTCCTGAAACAGATTATGAGTGCTCCAATTCC
ACCAGCTGCATGACAGTGTCCTGTCCTCGGCAACGTTACACTGCCAACTGCACGGTGCGGGATC
ACATCCATTGCTTGGGTAATCGTACTTTTCCCAAAATGCTATACTGTAATTGGACTGGAGGTTA
TAAGTGGTCGACTGCTCTGGCTCTAAGCATCACACTAGGTGGGTTTGGAGCAGACCGCTTCTAC
TTGGGCCAGTGGCGTGAAGGCCTGGGCAAGCTCTTCAGCTTTGGTGGCCTGGGAATATGGACAC
TAATAGATGTCTTGCTAATTGGAGTTGGCTACGTGGGACCAGCAGATGGCTCTTTGTACATTTA
GCTGTGGTTATGTGCTTCAGAGAGGAGCAGTCCTTAGGAAAAGGTCTATTGGCCTATAGTAACT
GATGTGTTGTGAGTTGTGTGTTTGTATGTTTTTAATGTACAGCATCTGTACTTTGCTTGCCTTG
ATAAAGGTAAAATAAAGAAGTTAAACACTGAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005320130	(Get FASTA)	NCBI Sequence Viewer
	XP_005320132	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008147.3
GenBank Protein	KAG3262681	(Get FASTA)	NCBI Sequence Viewer
	KAG3262682	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005320132 ⟸ XM_005320075

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAAAAGPLQRLRRLCRVLLFLSQFYILSGGESTEIPPYMMKCPSNGLCSRLPADCIDCATNFSC
VYGKPVTFDCTVKPSVTCVDQDFKSQKSFIINMTCRFCWQLPETDYECSNSTSCMTVSCPRQRY
TANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFS
FGGLGIWTLIDVLLIGVGYVGPADGSLYI

hide sequence

RefSeq Acc Id:	XP_005320130 ⟸ XM_005320073
- Peptide Label:	isoform X1
- UniProtKB:	I3MCX1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAAAGPLQRLRRLCRVLLFLSQFYILSGGGSLNLEHSQPLAQAIKDPGPTRTFTVVPRAAEST EIPPYMMKCPSNGLCSRLPADCIDCATNFSCVYGKPVTFDCTVKPSVTCVDQDFKSQKSFIINM TCRFCWQLPETDYECSNSTSCMTVSCPRQRYTANCTVRDHIHCLGNRTFPKMLYCNWTGGYKWS TALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI hide sequence

Ensembl Acc Id:

ENSSTOP00000008147 ⟸ ENSSTOT00000009087

Protein Domains

TM2

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009090	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009087.3	UniProtKB/TrEMBL
InterPro	TM2	UniProtKB/TrEMBL
	TM2_domain	UniProtKB/TrEMBL
NCBI Gene	Tm2d3	ENTREZGENE
PANTHER	BETA-AMYLOID BINDING PROTEIN-RELATED	UniProtKB/TrEMBL
	TM2 DOMAIN-CONTAINING PROTEIN 3	UniProtKB/TrEMBL
Pfam	TM2	UniProtKB/TrEMBL
UniProt	I3MCX1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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