Tbc1d23 (TBC1 domain family member 23) - Rat Genome Database

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Gene: Tbc1d23 (TBC1 domain family member 23) Ictidomys tridecemlineatus
Analyze
Symbol: Tbc1d23
Name: TBC1 domain family member 23
RGD ID: 12578989
Description: INVOLVED IN neuron projection development (ortholog); positive regulation of interleukin-6 production (ortholog); regulation of inflammatory response (ortholog); ASSOCIATED WITH genetic disease (ortholog); pontocerebellar hypoplasia (ortholog); pontocerebellar hypoplasia type 11 (ortholog); FOUND IN WASH complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602150,078,658 - 150,117,616 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366302,978,138 - 3,036,161 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366302,977,477 - 3,049,209 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tbc1d23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602150,078,658 - 150,117,616 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366302,978,138 - 3,036,161 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366302,977,477 - 3,049,209 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBC1D23
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383100,260,992 - 100,325,238 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3100,260,992 - 100,325,251 (+)EnsemblGRCh38hg38GRCh38
GRCh37399,979,836 - 100,044,082 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363101,462,546 - 101,525,205 (+)NCBINCBI36Build 36hg18NCBI36
Celera398,370,265 - 98,434,664 (+)NCBICelera
Cytogenetic Map3q12.1-q12.2NCBI
HuRef397,347,499 - 97,411,898 (+)NCBIHuRef
CHM1_1399,942,694 - 100,007,124 (+)NCBICHM1_1
T2T-CHM13v2.03102,966,332 - 103,030,580 (+)NCBIT2T-CHM13v2.0
Tbc1d23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391656,989,225 - 57,051,891 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1656,989,225 - 57,051,867 (-)EnsemblGRCm39 Ensembl
GRCm381657,168,862 - 57,231,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1657,168,862 - 57,231,504 (-)EnsemblGRCm38mm10GRCm38
MGSCv371657,168,975 - 57,231,579 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361657,090,221 - 57,152,825 (-)NCBIMGSCv36mm8
Celera1657,502,248 - 57,557,867 (-)NCBICelera
Cytogenetic Map16C1.1NCBI
cM Map1634.22NCBI
Tbc1d23
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81156,772,476 - 56,830,625 (+)NCBIGRCr8
mRatBN7.21143,303,355 - 43,361,507 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1143,303,355 - 43,361,503 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1152,071,380 - 52,129,543 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01144,732,981 - 44,791,147 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01143,857,073 - 43,915,241 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01145,401,396 - 45,459,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1145,401,403 - 45,459,821 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01148,594,422 - 48,652,592 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41144,274,253 - 44,285,320 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11144,284,324 - 44,342,915 (+)NCBI
Celera1143,092,874 - 43,151,132 (+)NCBICelera
Cytogenetic Map11q12NCBI
Tbc1d23
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554271,810,096 - 1,852,828 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554271,811,132 - 1,849,348 (+)NCBIChiLan1.0ChiLan1.0
TBC1D23
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2298,203,295 - 98,268,245 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1398,208,092 - 98,273,027 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0397,353,716 - 97,418,083 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13104,035,926 - 104,100,345 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3104,049,807 - 104,098,760 (+)Ensemblpanpan1.1panPan2
TBC1D23
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1336,883,199 - 6,939,788 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl336,883,336 - 6,938,318 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha337,038,751 - 7,095,338 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0337,021,917 - 7,078,683 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl337,021,999 - 7,078,680 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1336,909,713 - 6,966,471 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0336,957,938 - 7,014,541 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0337,287,702 - 7,344,394 (+)NCBIUU_Cfam_GSD_1.0
TBC1D23
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13158,665,077 - 158,729,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113158,665,083 - 158,729,285 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213168,397,816 - 168,416,370 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBC1D23
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12280,555,115 - 80,619,251 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2280,554,669 - 80,619,234 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604185,954,511 - 86,018,874 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tbc1d23
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478913,685,089 - 13,753,046 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478913,685,458 - 13,749,820 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000006890   ⟹   ENSSTOP00000006159
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366302,978,138 - 3,036,161 (-)Ensembl
RefSeq Acc Id: XM_040270476   ⟹   XP_040126410
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602150,078,658 - 150,115,959 (-)NCBI
RefSeq Acc Id: XM_040270477   ⟹   XP_040126411
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602150,078,658 - 150,117,616 (-)NCBI
RefSeq Acc Id: XM_040270478   ⟹   XP_040126412
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405602150,078,658 - 150,117,616 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040126410 (Get FASTA)   NCBI Sequence Viewer  
  XP_040126411 (Get FASTA)   NCBI Sequence Viewer  
  XP_040126412 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006159.3
GenBank Protein KAG3271611 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_040126411   ⟸   XM_040270477
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040126412   ⟸   XM_040270478
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040126410   ⟸   XM_040270476
- Peptide Label: isoform X1
- UniProtKB: I3M8Q4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSSTOP00000006159   ⟸   ENSSTOT00000006890
Protein Domains
Rab-GAP TBC   Rhodanese


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006882 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006890.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.250.10 UniProtKB/TrEMBL
  Ypt/Rab-GAP domain of gyp1p, domain 3 UniProtKB/TrEMBL
InterPro Rab-GTPase-TBC_dom UniProtKB/TrEMBL
  Rab-GTPase_TBC_sf UniProtKB/TrEMBL
  Rhodanese-like_dom UniProtKB/TrEMBL
  Rhodanese-like_dom_sf UniProtKB/TrEMBL
  TBC1D23 UniProtKB/TrEMBL
  TBC1D23_C UniProtKB/TrEMBL
NCBI Gene Tbc1d23 ENTREZGENE
PANTHER PTHR13297 UniProtKB/TrEMBL
  TBC1 DOMAIN FAMILY MEMBER 23 UniProtKB/TrEMBL
Pfam RabGAP-TBC UniProtKB/TrEMBL
  Rhodanese UniProtKB/TrEMBL
  TBC1D23_C UniProtKB/TrEMBL
PROSITE RHODANESE_3 UniProtKB/TrEMBL
  TBC_RABGAP UniProtKB/TrEMBL
Superfamily-SCOP SSF47923 UniProtKB/TrEMBL
  SSF52821 UniProtKB/TrEMBL
UniProt I3M8Q4 ENTREZGENE, UniProtKB/TrEMBL