Cabyr (calcium binding tyrosine phosphorylation regulated)

Gene: Cabyr (calcium binding tyrosine phosphorylation regulated) Ictidomys tridecemlineatus

Analyze

Symbol:

Cabyr

Name:

calcium binding tyrosine phosphorylation regulated

RGD ID:

12536504

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN sperm capacitation (inferred); ASSOCIATED WITH Colorectal Neoplasms (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN sperm end piece (ortholog); sperm principal piece (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

calcium binding tyrosine phosphorylation regulated, transcript variant X2; calcium binding tyrosine phosphorylation regulated, transcript variant X3; calcium binding tyrosine phosphorylation regulated, transcript variant X4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	60,270,142 - 60,298,230 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936550	3,520,717 - 3,547,712 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936550	3,519,470 - 3,545,938 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colorectal Neoplasms (ISO)

genetic disease (ISO)

intellectual disability (ISO)

male infertility (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

sperm capacitation (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

motile cilium (IEA)

nucleoplasm (IEA)

sperm end piece (ISO)

sperm fibrous sheath (IEA)

sperm principal piece (ISO)

Molecular Function

calcium ion binding (IEA)

enzyme binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Cabyr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	60,270,142 - 60,298,230 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936550	3,520,717 - 3,547,712 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936550	3,519,470 - 3,545,938 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CABYR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	24,139,062 - 24,161,600 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	24,138,987 - 24,161,600 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	21,719,026 - 21,741,564 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	19,972,953 - 19,995,562 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	19,972,952 - 19,995,562	NCBI
Celera	18	18,535,262 - 18,557,874 (+)	NCBI		Celera
Cytogenetic Map	18	q11.2	NCBI
HuRef	18	18,574,968 - 18,597,620 (+)	NCBI		HuRef
CHM1_1	18	21,646,183 - 21,668,832 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	24,333,387 - 24,355,939 (+)	NCBI		T2T-CHM13v2.0

Cabyr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	12,874,141 - 12,888,203 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	12,873,379 - 12,888,317 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	12,740,825 - 12,755,146 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	12,740,322 - 12,755,260 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	12,899,864 - 12,913,651 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	12,884,524 - 12,898,311 (+)	NCBI		MGSCv36	mm8
Celera	18	12,973,145 - 12,986,930 (+)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI
cM Map	18	6.77	NCBI

Cabyr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	4,166,790 - 4,178,570 (+)	NCBI		GRCr8
mRatBN7.2	18	3,892,062 - 3,904,391 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	3,892,132 - 3,903,840 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	4,115,194 - 4,124,531 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	4,902,753 - 4,912,090 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	4,161,848 - 4,171,159 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	4,082,175 - 4,096,650 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	4,084,228 - 4,095,936 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	4,076,885 - 4,088,625 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	18	3,947,544 - 3,959,262 (+)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

Cabyr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	12,508,538 - 12,529,230 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	12,508,524 - 12,529,230 (+)	NCBI	ChiLan1.0	ChiLan1.0

CABYR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	41,569,876 - 41,593,728 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	27,261,931 - 27,286,326 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	17,391,217 - 17,414,683 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	21,014,584 - 21,037,082 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	21,014,584 - 21,037,082 (+)	Ensembl	panpan1.1		panPan2

CABYR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	64,223,591 - 64,239,362 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	64,223,579 - 64,239,277 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	63,672,523 - 63,685,535 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	64,282,146 - 64,297,921 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	64,282,146 - 64,297,849 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	63,951,924 - 63,964,930 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	63,967,190 - 63,980,199 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	64,271,739 - 64,284,749 (-)	NCBI		UU_Cfam_GSD_1.0

CABYR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	108,969,948 - 108,997,297 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	108,971,340 - 108,997,295 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	101,637,498 - 101,663,520 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CABYR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	56,371,478 - 56,395,160 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	56,371,342 - 56,394,466 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	31,121,123 - 31,141,932 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cabyr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624770	8,055,008 - 8,079,925 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005329043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013360221	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021728929	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040274314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040274316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040274320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040274324	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040274328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002484372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000015491 ⟹ ENSSTOP00000016446

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936550	3,520,717 - 3,547,712 (+)	Ensembl

RefSeq Acc Id:

XM_013360221 ⟹ XP_013215675

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,270,142 - 60,296,605 (-)	NCBI
SpeTri2.0	NW_004936550	3,519,470 - 3,545,938 (+)	NCBI

Sequence:

show sequence

TGTGACGCACGCATTGACGTCTCCAGGGTTATAAAAGCCCCGCCCAGGTCGGTTTTTCACAGGA
GCCGCCGGCGAGGGGGCAACGAGGAAGCTCGCCCGAGCTTAGCCGGAAAGAGGAAGTTGAGATT
ACAGACATCCTGCCAGAATGCTTTCTTCAAAGCCCAGACTTGTCGTACCCTATGGCCTCAAGAC
TCTACTCGAGGGAGTTAGCAGAGCTGTTCTCAAAACCAAACCATCAAACATCACCCAGTTTGCA
GCGATTTATTTTAAAGAACTTATTGTATTTAGAGAAGGGAATAATTCTCTGGATATAAAAGATC
TGGTTAAACAATTTCATCAGCTTAAAGTAGAGAAGTGGTCAGAAGGAGTGACACAGGAGAAGAA
ATCAGAACCAGAACGAACACCTGTAGTTTCCCAAGAACCTACACGGATGGAAAAATCCACGGAC
ACAGAGGAGGATAATATATCTGCACCACAGTTTAGCAACAAGACCACCCAGTTTCCATCAATTA
ATACTGAGTGCCCACAGACTGAGGGGACAAGCGAAGCAGTTCGTGGTCCTTCTTCCAAACCAGT
CACCCCCAAGACTACCACTCCACCCTCATCACCATCTCCAGCAGCTGTCTCAGCAGAGTTTGCC
TATGTCCCAGCTGACCCAGCTCAGTTTGCCACTCAGATGTTAGCACTAGCAACAAGCGAAGCAG
GACAACCACCACCATATTCTAACATGTGGACCCTTTACTGTCTAACTGATATGAATCAACAAAG
TCGCCCATCACCGCCACCAGCACCTGGGCCTTTTCCCCAAGCAACCCTCTATTTATCTAATCCT
AAGGATCCACAGTTTCTGCAGAATCCACCGCAAGTTACTTCTCCAACTTATGTGATGATGGAGG
ACACCAAGAAGACCAGTGCCCCACCTTTTATTTTAGTAGGCTCAAATGTTCAGGAAGCACAGGA
TTGGAAACCTCTTCCTGGACATGCTGTTGTCTCACAGTCAGATGGCATGAAGAGATATGCTGCA
GTACAAGTACCCATTGCTATTCCTGCAGATCAGAAATTCCAGAAACATACCCTAAATCCCCCAA
ATGCTAGTCCTCCTTCAAGTGGAAAAGATGTCCCCAGACCACAAAGCCCAGTTTTTCTTTCTGT
TGCTTTCCCAGTAGAAGATGTAGCTAAAAAAGGTACAGGATCTGGTGACAAACGTTCTCCCTTT
GGAAGTTATGGTATTGCTGGAGAGATTACTGTGACTACTGCCCATGTTCGCAGAGCAGAAACTA
AAAACTGATGCCGAAAATGACGCTGTTTTGAGTCAACGTTCAAGGTGGAGTCTGCCACCAAGCG
TTATATCAATAAACTTCCTGCAAGCATTAAA

hide sequence

RefSeq Acc Id:

XM_040274314 ⟹ XP_040130248

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,271,429 - 60,296,606 (-)	NCBI

RefSeq Acc Id:

XM_040274316 ⟹ XP_040130250

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,270,142 - 60,296,606 (-)	NCBI

RefSeq Acc Id:

XM_040274320 ⟹ XP_040130254

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,271,429 - 60,298,230 (-)	NCBI

RefSeq Acc Id:

XM_040274324 ⟹ XP_040130258

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,271,429 - 60,295,839 (-)	NCBI

RefSeq Acc Id:

XM_040274328 ⟹ XP_040130262

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	60,271,429 - 60,295,839 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_013215675	(Get FASTA)	NCBI Sequence Viewer
	XP_040130248	(Get FASTA)	NCBI Sequence Viewer
	XP_040130250	(Get FASTA)	NCBI Sequence Viewer
	XP_040130254	(Get FASTA)	NCBI Sequence Viewer
	XP_040130258	(Get FASTA)	NCBI Sequence Viewer
	XP_040130262	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016446.2
GenBank Protein	KAG3294072	(Get FASTA)	NCBI Sequence Viewer
	KAG3294073	(Get FASTA)	NCBI Sequence Viewer
	KAG3294074	(Get FASTA)	NCBI Sequence Viewer
	KAG3294075	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013215675 ⟸ XM_013360221
- Peptide Label:	isoform X2
- UniProtKB:	I3MWF1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSSKPRLVVPYGLKTLLEGVSRAVLKTKPSNITQFAAIYFKELIVFREGNNSLDIKDLVKQFH QLKVEKWSEGVTQEKKSEPERTPVVSQEPTRMEKSTDTEEDNISAPQFSNKTTQFPSINTECPQ TEGTSEAVRGPSSKPVTPKTTTPPSSPSPAAVSAEFAYVPADPAQFATQMLALATSEAGQPPPY SNMWTLYCLTDMNQQSRPSPPPAPGPFPQATLYLSNPKDPQFLQNPPQVTSPTYVMMEDTKKTS APPFILVGSNVQEAQDWKPLPGHAVVSQSDGMKRYAAVQVPIAIPADQKFQKHTLNPPNASPPS SGKDVPRPQSPVFLSVAFPVEDVAKKGTGSGDKRSPFGSYGIAGEITVTTAHVRRAETKN hide sequence

RefSeq Acc Id:	XP_040130250 ⟸ XM_040274316
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040130254 ⟸ XM_040274320
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040130248 ⟸ XM_040274314
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040130262 ⟸ XM_040274328
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040130258 ⟸ XM_040274324
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSSTOP00000016446 ⟸ ENSSTOT00000015491

Protein Domains

RIIa

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015498	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015491.3	UniProtKB/TrEMBL
Gene3D-CATH	cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain	UniProtKB/TrEMBL
InterPro	CABYR	UniProtKB/TrEMBL
	cAMP_dep_PK_reg_su_I/II_a/b	UniProtKB/TrEMBL
	DD_CABYR_SP17	UniProtKB/TrEMBL
NCBI Gene	Cabyr	ENTREZGENE
PANTHER	CALCIUM-BINDING TYROSINE PHOSPHORYLATION-REGULATED PROTEIN	UniProtKB/TrEMBL
	PTHR15494	UniProtKB/TrEMBL
Pfam	RIIa	UniProtKB/TrEMBL
SMART	RIIa	UniProtKB/TrEMBL
Superfamily-SCOP	Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	UniProtKB/TrEMBL
UniProt	I3MWF1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

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Imported Disease Annotations - CTD

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