Bmp5 (bone morphogenetic protein 5) - Rat Genome Database

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Gene: Bmp5 (bone morphogenetic protein 5) Ictidomys tridecemlineatus
Analyze
Symbol: Bmp5
Name: bone morphogenetic protein 5
RGD ID: 12525830
Description: ENCODES a protein that exhibits BMP receptor binding (inferred); cytokine activity (inferred); growth factor activity (inferred); INVOLVED IN anterior head development (ortholog); ear development (ortholog); male genitalia development (ortholog); ASSOCIATED WITH genetic disease (ortholog); Meier-Gorlin syndrome (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494658,495,816 - 58,609,333 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364765,350,870 - 5,464,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364765,350,870 - 5,464,561 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bmp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494658,495,816 - 58,609,333 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364765,350,870 - 5,464,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364765,350,870 - 5,464,561 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38655,753,653 - 55,875,590 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl655,753,653 - 55,875,590 (-)EnsemblGRCh38hg38GRCh38
GRCh37655,618,451 - 55,740,388 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36655,728,195 - 55,848,334 (-)NCBINCBI36Build 36hg18NCBI36
Build 34655,728,198 - 55,848,334NCBI
Celera657,281,444 - 57,401,579 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef655,455,271 - 55,575,481 (-)NCBIHuRef
CHM1_1655,623,337 - 55,743,453 (-)NCBICHM1_1
T2T-CHM13v2.0655,593,278 - 55,715,204 (-)NCBIT2T-CHM13v2.0
Bmp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,682,647 - 75,807,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,682,646 - 75,807,592 (+)EnsemblGRCm39 Ensembl
GRCm38975,775,365 - 75,900,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,775,364 - 75,900,310 (+)EnsemblGRCm38mm10GRCm38
MGSCv37975,623,172 - 75,746,824 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,561,274 - 75,684,926 (+)NCBIMGSCv36mm8
Celera972,947,674 - 73,071,783 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.34NCBI
Bmp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8885,397,629 - 85,520,374 (+)NCBIGRCr8
mRatBN7.2876,517,164 - 76,639,925 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,517,164 - 76,639,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx882,030,944 - 82,153,707 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0880,289,767 - 80,412,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0878,130,272 - 78,253,044 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,669,466 - 82,950,273 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,878,941 - 82,950,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,266,949 - 82,526,447 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,593,053 - 80,717,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,610,468 - 80,733,833 (+)NCBI
Celera876,306,530 - 76,429,126 (+)NCBICelera
Cytogenetic Map8q24NCBI
Bmp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955411450,674 - 558,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955411450,674 - 557,213 (+)NCBIChiLan1.0ChiLan1.0
BMP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2570,217,543 - 70,341,856 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1666,094,284 - 66,218,613 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0655,302,721 - 55,425,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1656,936,871 - 57,058,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl656,936,850 - 57,059,519 (-)Ensemblpanpan1.1panPan2
BMP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,089,429 - 23,202,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBIUU_Cfam_GSD_1.0
BMP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,344,822 - 25,470,470 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,344,924 - 25,468,430 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,657,701 - 29,658,702 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2729,873,198 - 29,939,042 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11715,696,379 - 15,819,454 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1715,696,580 - 15,819,564 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605821,842,528 - 21,973,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248503,322,782 - 3,481,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248503,324,553 - 3,481,439 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000002426   ⟹   ENSSTOP00000002171
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364765,350,870 - 5,464,354 (+)Ensembl
RefSeq Acc Id: XM_040282834   ⟹   XP_040138768
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494658,495,816 - 58,609,333 (-)NCBI
RefSeq Acc Id: XM_040282835   ⟹   XP_040138769
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494658,497,640 - 58,609,333 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040138768 (Get FASTA)   NCBI Sequence Viewer  
  XP_040138769 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002171.2
GenBank Protein KAG3289665 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040138768   ⟸   XM_040282834
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040138769   ⟸   XM_040282835
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000002171   ⟸   ENSSTOT00000002426
Protein Domains
TGF-beta family profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002425 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002426.3 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.970 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene Bmp5 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 5 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt I3M0E4_ICTTR UniProtKB/TrEMBL