BMP5 (bone morphogenetic protein 5) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: BMP5 (bone morphogenetic protein 5) Canis lupus familiaris
Analyze
Symbol: BMP5
Name: bone morphogenetic protein 5
RGD ID: 12097454
Description: ENCODES a protein that exhibits BMP receptor binding (inferred); growth factor activity (inferred); INVOLVED IN allantois development (ortholog); anterior head development (ortholog); cardiac muscle tissue development (ortholog); ASSOCIATED WITH Congenital Microtia (ortholog); Meier-Gorlin syndrome (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,089,429 - 23,202,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
BMP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,089,429 - 23,202,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBIUU_Cfam_GSD_1.0
BMP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38655,753,653 - 55,875,590 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl655,753,653 - 55,875,590 (-)EnsemblGRCh38hg38GRCh38
GRCh37655,618,451 - 55,740,388 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36655,728,195 - 55,848,334 (-)NCBINCBI36Build 36hg18NCBI36
Build 34655,728,198 - 55,848,334NCBI
Celera657,281,444 - 57,401,579 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef655,455,271 - 55,575,481 (-)NCBIHuRef
CHM1_1655,623,337 - 55,743,453 (-)NCBICHM1_1
T2T-CHM13v2.0655,593,278 - 55,715,204 (-)NCBIT2T-CHM13v2.0
Bmp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,682,647 - 75,807,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,682,646 - 75,807,592 (+)EnsemblGRCm39 Ensembl
GRCm38975,775,365 - 75,900,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,775,364 - 75,900,310 (+)EnsemblGRCm38mm10GRCm38
MGSCv37975,623,172 - 75,746,824 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,561,274 - 75,684,926 (+)NCBIMGSCv36mm8
Celera972,947,674 - 73,071,783 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.34NCBI
Bmp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8885,397,629 - 85,520,374 (+)NCBIGRCr8
mRatBN7.2876,517,164 - 76,639,925 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,517,164 - 76,639,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx882,030,944 - 82,153,707 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0880,289,767 - 80,412,506 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0878,130,272 - 78,253,044 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0882,669,466 - 82,950,273 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,878,941 - 82,950,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,266,949 - 82,526,447 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,593,053 - 80,717,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,610,468 - 80,733,833 (+)NCBI
Celera876,306,530 - 76,429,126 (+)NCBICelera
Cytogenetic Map8q24NCBI
Bmp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955411450,674 - 558,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955411450,674 - 557,213 (+)NCBIChiLan1.0ChiLan1.0
BMP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2570,217,543 - 70,341,856 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1666,094,284 - 66,218,613 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0655,302,721 - 55,425,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1656,936,871 - 57,058,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl656,936,850 - 57,059,519 (-)Ensemblpanpan1.1panPan2
Bmp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494658,495,816 - 58,609,333 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364765,350,870 - 5,464,354 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364765,350,870 - 5,464,561 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,344,822 - 25,470,470 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,344,924 - 25,468,430 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,657,701 - 29,658,702 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2729,873,198 - 29,939,042 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11715,696,379 - 15,819,454 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1715,696,580 - 15,819,564 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605821,842,528 - 21,973,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248503,322,782 - 3,481,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248503,324,553 - 3,481,439 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in BMP5
903 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000003670   ⟹   ENSCAFP00000003394
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000074220   ⟹   ENSCAFP00000047087
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1223,089,886 - 23,202,348 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845021014   ⟹   ENSCAFP00845016516
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845021041   ⟹   ENSCAFP00845016541
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)Ensembl
RefSeq Acc Id: XM_038492078   ⟹   XP_038348006
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBI
RefSeq Acc Id: XM_038554362   ⟹   XP_038410290
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBI
RefSeq Acc Id: XM_038618226   ⟹   XP_038474154
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBI
RefSeq Acc Id: XM_038683795   ⟹   XP_038539723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBI
RefSeq Acc Id: XM_532179   ⟹   XP_532179
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11223,089,429 - 23,201,426 (-)NCBI
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBI
Sequence:
RefSeq Acc Id: XP_532179   ⟸   XM_532179
- UniProtKB: A0A8C0NEM6 (UniProtKB/TrEMBL),   A0A8I3RYW2 (UniProtKB/TrEMBL),   A0A8I3NK03 (UniProtKB/TrEMBL),   A0A8P0SZX8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000047087   ⟸   ENSCAFT00000074220
Ensembl Acc Id: ENSCAFP00000003394   ⟸   ENSCAFT00000003670
RefSeq Acc Id: XP_038348006   ⟸   XM_038492078
RefSeq Acc Id: XP_038474154   ⟸   XM_038618226
RefSeq Acc Id: XP_038539723   ⟸   XM_038683795
- UniProtKB: A0A8C0NEM6 (UniProtKB/TrEMBL),   A0A8I3RYW2 (UniProtKB/TrEMBL),   A0A8I3NK03 (UniProtKB/TrEMBL),   A0A8P0SZX8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410290   ⟸   XM_038554362
- UniProtKB: A0A8C0NEM6 (UniProtKB/TrEMBL),   A0A8I3NK03 (UniProtKB/TrEMBL),   A0A8I3RYW2 (UniProtKB/TrEMBL),   A0A8P0SZX8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845016516   ⟸   ENSCAFT00845021014
Ensembl Acc Id: ENSCAFP00845016541   ⟸   ENSCAFT00845021041
Protein Domains
TGF-beta family profile

Promoters
RGD ID:13685473
Promoter ID:EPDNEW_C3540
Type:single initiation site
Name:BMP5_1
Description:bone morphogenetic protein 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11223,202,165 - 23,202,225EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002345 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014808 UniProtKB/TrEMBL
  ENSCAFG00040007667 UniProtKB/TrEMBL
  ENSCAFG00845011840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000003670.5 UniProtKB/TrEMBL
  ENSCAFT00000074220.2 UniProtKB/TrEMBL
  ENSCAFT00030027332.1 UniProtKB/TrEMBL
  ENSCAFT00040014272.1 UniProtKB/TrEMBL
  ENSCAFT00845021014.1 UniProtKB/TrEMBL
  ENSCAFT00845021041 ENTREZGENE
  ENSCAFT00845021041.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
  2.60.120.970 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
KEGG Report cfa:474944 UniProtKB/TrEMBL
NCBI Gene BMP5 ENTREZGENE
PANTHER BONE MORPHOGENETIC PROTEIN 5 UniProtKB/TrEMBL
  PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A8C0NEM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NK03 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RYW2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SZX8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:38481 ENTREZGENE