BMP5 (bone morphogenetic protein 5) - Rat Genome Database

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Gene: BMP5 (bone morphogenetic protein 5) Canis lupus familiaris
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Symbol: BMP5
Name: bone morphogenetic protein 5
RGD ID: 12097454
Description: ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN allantois development (ortholog); anterior head development (ortholog); cardiac muscle tissue development (ortholog); ASSOCIATED WITH Meier-Gorlin syndrome (ortholog); FOUND IN extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,089,429 - 23,202,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
BMP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11223,089,429 - 23,202,176 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBIUU_Cfam_GSD_1.0
BMP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38655,753,653 - 55,875,590 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl655,753,653 - 55,875,590 (-)EnsemblGRCh38hg38GRCh38
GRCh37655,618,451 - 55,740,388 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36655,728,195 - 55,848,334 (-)NCBINCBI36Build 36hg18NCBI36
Build 34655,728,198 - 55,848,334NCBI
Celera657,281,444 - 57,401,579 (-)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef655,455,271 - 55,575,481 (-)NCBIHuRef
CHM1_1655,623,337 - 55,743,453 (-)NCBICHM1_1
T2T-CHM13v2.0655,593,278 - 55,715,204 (-)NCBIT2T-CHM13v2.0
Bmp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39975,682,647 - 75,807,598 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl975,682,646 - 75,807,592 (+)EnsemblGRCm39 Ensembl
GRCm38975,775,365 - 75,900,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl975,775,364 - 75,900,310 (+)EnsemblGRCm38mm10GRCm38
MGSCv37975,623,172 - 75,746,824 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36975,561,274 - 75,684,926 (+)NCBIMGSCv36mm8
Celera972,947,674 - 73,071,783 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map942.34NCBI
Bmp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2876,517,164 - 76,639,925 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl876,517,164 - 76,639,925 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx882,030,944 - 82,153,707 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0880,289,767 - 80,412,506 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0878,130,272 - 78,253,044 (+)NCBIRnor_WKY
Rnor_6.0882,669,466 - 82,950,273 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl882,878,941 - 82,950,273 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0882,266,949 - 82,526,447 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4880,593,053 - 80,717,015 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1880,610,468 - 80,733,833 (+)NCBI
Celera876,306,530 - 76,429,126 (+)NCBICelera
Cytogenetic Map8q24NCBI
Bmp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955411450,674 - 558,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955411450,674 - 557,213 (+)NCBIChiLan1.0ChiLan1.0
BMP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1656,936,871 - 57,058,801 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl656,936,850 - 57,059,519 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0655,302,721 - 55,425,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Bmp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494658,495,816 - 58,609,333 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364765,350,870 - 5,464,561 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,344,822 - 25,470,470 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,344,924 - 25,468,430 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,657,701 - 29,658,702 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2729,873,198 - 29,939,042 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BMP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11715,696,379 - 15,819,454 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1715,696,580 - 15,819,564 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605821,842,528 - 21,973,085 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bmp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248503,322,782 - 3,481,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248503,324,553 - 3,481,439 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 15 4 4 4 6 10
Below cutoff 7 2 6 2 6 2 6 8 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000003670   ⟹   ENSCAFP00000003394
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1223,089,459 - 23,202,348 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000074220   ⟹   ENSCAFP00000047087
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1223,089,886 - 23,202,348 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021014   ⟹   ENSCAFP00845016516
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845021041   ⟹   ENSCAFP00845016541
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1223,587,187 - 23,699,514 (-)Ensembl
RefSeq Acc Id: XM_038492078   ⟹   XP_038348006
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11223,083,296 - 23,195,652 (-)NCBI
RefSeq Acc Id: XM_038554362   ⟹   XP_038410290
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01223,319,382 - 23,432,016 (-)NCBI
RefSeq Acc Id: XM_038618226   ⟹   XP_038474154
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01223,187,441 - 23,299,694 (-)NCBI
RefSeq Acc Id: XM_038683795   ⟹   XP_038539723
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01223,587,541 - 23,700,170 (-)NCBI
RefSeq Acc Id: XM_532179   ⟹   XP_532179
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11223,089,429 - 23,201,426 (-)NCBI
Dog10K_Boxer_Tasha1222,980,188 - 23,092,541 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_038348006 (Get FASTA)   NCBI Sequence Viewer  
  XP_038410290 (Get FASTA)   NCBI Sequence Viewer  
  XP_038474154 (Get FASTA)   NCBI Sequence Viewer  
  XP_038539723 (Get FASTA)   NCBI Sequence Viewer  
  XP_532179 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_532179   ⟸   XM_532179
- UniProtKB: E2RNJ0 (UniProtKB/TrEMBL),   A0A8C0NEM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000047087   ⟸   ENSCAFT00000074220
RefSeq Acc Id: ENSCAFP00000003394   ⟸   ENSCAFT00000003670
RefSeq Acc Id: XP_038348006   ⟸   XM_038492078
RefSeq Acc Id: XP_038474154   ⟸   XM_038618226
RefSeq Acc Id: XP_038539723   ⟸   XM_038683795
- UniProtKB: A0A8C0NEM6 (UniProtKB/TrEMBL),   E2RNJ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038410290   ⟸   XM_038554362
RefSeq Acc Id: ENSCAFP00845016516   ⟸   ENSCAFT00845021014
RefSeq Acc Id: ENSCAFP00845016541   ⟸   ENSCAFT00845021041
Protein Domains
TGF_BETA_2

Promoters
RGD ID:13685473
Promoter ID:EPDNEW_C3540
Type:single initiation site
Name:BMP5_1
Description:bone morphogenetic protein 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11223,202,165 - 23,202,225EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002345 Ensembl
  ENSCAFG00030014808 UniProtKB/TrEMBL
  ENSCAFG00040007667 UniProtKB/TrEMBL
  ENSCAFG00845011840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030023847.1 UniProtKB/TrEMBL
  ENSCAFP00040012348 UniProtKB/TrEMBL
  ENSCAFP00845016516.1 UniProtKB/TrEMBL
  ENSCAFP00845016541 ENTREZGENE
  ENSCAFP00845016541.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030027332.1 UniProtKB/TrEMBL
  ENSCAFT00040014272 UniProtKB/TrEMBL
  ENSCAFT00845021014.1 UniProtKB/TrEMBL
  ENSCAFT00845021041 ENTREZGENE
  ENSCAFT00845021041.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-b_propeptide UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene BMP5 ENTREZGENE
PANTHER PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
  TGFb_propeptide UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A8C0NEM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NK03_CANLF UniProtKB/TrEMBL
  A0A8I3RYW2_CANLF UniProtKB/TrEMBL
  E2RNJ0 ENTREZGENE
VGNC ID VGNC:38481 ENTREZGENE