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Gene: Hk3 (hexokinase 3) Ictidomys tridecemlineatus

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Symbol:

Hk3

Name:

hexokinase 3

RGD ID:

12525261

Description:

ENCODES a protein that exhibits enzyme binding (ortholog); hexokinase activity (ortholog); hormone binding (ortholog); INVOLVED IN fructose 6-phosphate metabolic process (ortholog); negative regulation of hydrogen peroxide-mediated programmed cell death (ortholog); PARTICIPATES IN glycolysis pathway; ASSOCIATED WITH Chromosome 5, Trisomy 5q (ortholog); Ehlers-Danlos syndrome dermatosparaxis type (ortholog); Ehlers-Danlos syndrome spondylodysplastic type 2 (ortholog); FOUND IN protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

hexokinase-3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HK3 (hexokinase 3)	NCBI	Ortholog
Mus musculus (house mouse):	Hk3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hk3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hk3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HK3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	HK3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HK3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	HK3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hk3 (hexokinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936597	1,122,648 - 1,138,396 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936597	1,122,648 - 1,143,342 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chromosome 5, Trisomy 5q (ISO)

Ehlers-Danlos syndrome dermatosparaxis type (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

liver disease (ISO)

long QT syndrome (ISO)

Marfanoid Mental Retardation Syndrome, Autosomal (ISO)

Sotos syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

carbohydrate phosphorylation (IEA)

fructose 6-phosphate metabolic process (ISO)

glucose 6-phosphate metabolic process (IEA)

glucose metabolic process (IEA)

glycolytic process (IEA)

hexose metabolic process (IEA)

intracellular glucose homeostasis (IEA)

negative regulation of hydrogen peroxide-mediated programmed cell death (ISO)

Cellular Component

cytosol (IEA)

mitochondrion (IEA)

protein-containing complex (ISO)

Molecular Function

ATP binding (IEA)

D-glucose binding (IEA)

enzyme binding (ISO)

fructokinase activity (IEA)

glucokinase activity (IEA)

hexokinase activity (IEA,ISO)

hormone binding (ISO)

kinase activity (IEA)

mannokinase activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

glycolysis pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936597	1,122,648 - 1,138,396 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936597	1,122,648 - 1,143,342 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	176,880,869 - 176,899,346 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	176,880,869 - 176,899,346 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	176,307,870 - 176,326,347 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	176,240,476 - 176,258,921 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	176,240,476 - 176,258,921	NCBI
Celera	5	172,175,889 - 172,194,352 (+)	NCBI		Celera
Cytogenetic Map	5	q35.2	NCBI
HuRef	5	171,230,595 - 171,249,057 (-)	NCBI		HuRef
CHM1_1	5	175,740,078 - 175,758,541 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	177,426,695 - 177,445,172 (-)	NCBI		T2T-CHM13v2.0

Hk3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	55,153,798 - 55,169,233 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	55,153,798 - 55,169,198 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	55,005,985 - 55,021,475 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	55,005,985 - 55,021,385 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	55,107,347 - 55,122,695 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	55,015,608 - 55,030,956 (-)	NCBI		MGSCv36	mm8
Celera	13	56,066,914 - 56,082,258 (-)	NCBI		Celera
Cytogenetic Map	13	B1	NCBI
cM Map	13	29.8	NCBI

Hk3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	9,602,119 - 9,620,038 (+)	NCBI		GRCr8
mRatBN7.2	17	9,596,950 - 9,614,847 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	9,599,865 - 9,614,863 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	9,617,278 - 9,632,258 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	11,146,346 - 11,161,323 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	9,613,681 - 9,628,663 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	10,134,726 - 10,152,976 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	10,137,974 - 10,152,956 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	12,243,962 - 12,261,662 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	15,651,953 - 15,669,109 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	17	15,651,952 - 15,669,109 (+)	NCBI
Celera	17	9,677,906 - 9,692,837 (+)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

Hk3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	29,132,717 - 29,146,280 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	29,132,717 - 29,149,030 (-)	NCBI	ChiLan1.0	ChiLan1.0

HK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	171,964,336 - 171,988,216 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	170,103,888 - 170,122,200 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	172,181,600 - 172,200,418 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	179,248,348 - 179,266,657 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	179,248,155 - 179,266,533 (-)	Ensembl	panpan1.1		panPan2

HK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	36,471,389 - 36,491,757 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	36,472,949 - 36,529,903 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	36,439,140 - 36,464,621 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	36,838,190 - 36,863,673 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	36,838,410 - 36,895,345 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	36,664,279 - 36,689,761 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	36,852,128 - 36,877,608 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	37,360,223 - 37,385,703 (+)	NCBI		UU_Cfam_GSD_1.0

HK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	81,042,755 - 81,060,826 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	81,042,401 - 81,060,832 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	82,650,985 - 82,669,061 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

HK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	78,888,087 - 78,908,608 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	78,888,291 - 78,906,995 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666075	10,050,093 - 10,071,104 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hk3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	13,245,845 - 13,262,184 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	13,245,822 - 13,262,300 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273104	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273105	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040273106	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000004073 ⟹ ENSSTOP00000003653

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936597	1,122,648 - 1,138,396 (-)	Ensembl

RefSeq Acc Id:

XM_005333157 ⟹ XP_005333214

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI
SpeTri2.0	NW_004936597	1,122,648 - 1,143,342 (-)	NCBI

Sequence:

show sequence

CCCAGACCCCAGCCGCCCTGCAAAAAAAAATTCTTAGAGCATAGAATATTTGAGAGAAGTGCCC
TGCCATTTTCCCTAGGATTTTTTAGGTATGCAGTCTGGTATTAGTTCCTATGTGATTATTTTTT
CAAAATAGATTAACTGGTAGAGATGCCAGGCATAGTCATATGTTCAAAATAATATTGGTTTTTC
TTCCTGTCAAAGGTCATAGCAGCAATAGTGACTGTTATTCCACTAACATTACTGGGGTAATGCA
TATTCTTCCATTACTTTGCCTGGGAGCTTCCACTGCAGAACAAAATATGGTCTGTCCTCAGTGT
ATAAGCAGACTCCAAAATGAGAGGTTGTGAAATGGTAGAGGTAGCTACCTGAGGGAGATGAACA
AACAGGTATCTTAAGAAAGCTAGCTTTGGCCCCAGCTGCTTTGAAGATGGCTTGAGAGATTGTA
GGAGGTAGCTGTTGACCAGGAAGAGATCTTGCGTCATGATAAATGGGCACACAATGCAGACTCT
TCTGATTTATTGTATCCCACGTTACCATTTCCTTTATTTTAATTAAAATTAGTTAGCCTGGGGA
AGGTAGCTAGAATGTAAGAATCAGCACAGACGTTAAGACACTGTATCCTGCTCTAGGGACATTT
GCACACGAGCTCCTTCAGTTAAAAGGCAGGCTGCTCACTGCCATCCATAGATGATGTCTTGTTG
TTGGATGGTACTGACATTGCAGCTATATCACGTATGTAATAGCTATTTTTTTTGAGCAGTTACC
ATAGACCAGGTAATGAATGTACCTTCATTACATTTAATCCTCATGGCAACCCTATGAAATAGAT
ATTATAACCCATTTTCAGATGAGGAAACAAAGGCTCAGAGGAACAAATAAAGCCACTCTTTGTT
CATGTCAGTAAAACTGTGGTGCTGCTACTCTTCAGTTCTAAAGAATGCTTTATTTTGACTCTAG
TATTCATTATTTTCCTTCTAAGGAAAAGTAGTTTATCAGTTAAGTCCCAACTGCTTAACCCTTG
CTCATCATCTTTCTCATTAAATGGCACTTTATTGGAGGTAGAGCTCTGTAAACAGGGGACCGTG
TTTCTCTCTCTGCCTGAAGAAAAGGGAAAGAGCTGTTTCTCAAAGGTAAATTATTTAACTTAAA
TATGAGCAGTTGCCATAGAACTTGGTTCAGTGGCACGAGGGTATGGATCAGCCAGACCAGGAAC
CAAAGGCTTATTTATTAGTTAATGGAGAATGAAGGGAAGAACAATCACTGTCCCCCACCTCAAA
CACACCTACCCCAGCTATCTTCAATAAGGGCTGCTGCTGCTTTTTTTTTTTTTTTTCCTTCCCT
GTGCTATGGTCTTACAGGGGGAGGATTAGTGAAAAAGGTACAAGAGACAAAGTAGAAAGTGTGT
CAAACCAAACCAAGTCTGCTCTCTGCTTCTGATACAAGTTACCCAGCCTCTCTGTACTTAGTTT
TCTTTGCCCACAAAATAAGAAAAATTATGCTTACATATTTCTAAGGATTAATATAATGTATATA
AAAGTTGTACCACAATGTCTGTCACATAGAAGATAGGGAGTTAGTGGCAGCAGTTGTTACTAAT
TTGACATAAGTCTTGTGTGTCATAAGTAGTGTTGCAGTGAGGGGTGGAAGGACCAGAGAAAGGT
AGAGTGCAGATGCAAGAGGAGATATTTCTGAGGACTGAGCACTCACTCAGAGGATCTACTATAG
CCCCATCAACCACCAGCCTGCCACAGAAAGCTTGGTTCCTGTACATTTGGAGCTCTCCTGGGGA
CCCTGGGTGGTTCTTCTGAAAGACAGGAAGCGGCTATAATGCTGGTGTTGCCAACTCATGGAAA
GCTGGGAAGCTTCATGAGCTTCACAAGCTATTGCCATAAATTGGGAGAAAGACAGAGATTGCTC
TGTGTCAGGCATTGTAGCTGTGTTATTTCATCCTTACAACAGCCCTCCAAAAGATGTTGTGCCT
GGCCCACTTCCCTTGGGCATTCACCCTTCTACTGCATTCCCACAGGGCTCTTTTGGAAGTACCT
ATGATGCCCTGCCTGAGGACTTCTTTTGGCTTATGTTGGTACATGCTAGAAGTTCCAGGGGAGC
AGTGCCCTGGGGTAGCTCTCAGCCAGTGAAAATGAAAGTTGAATGATAAATACCCCGTCTTCTT
TACCCCTCAGGTGGAATAAGGTGTATTCTATTCTTCTTTCTGTTGAATTGAGTGTCAGTACCTC
CCAGCAACGACTTAATTATGTACCCTTCTCTGTTGGCATCTTTCCCTTGCTACCTTGCTTCCAA
CTCTCCTGTCAGGACCAGGACTAGGTAACAGTTTCATGTAAATGCAGGGTTAGAACTTGAGAGG
TCTTGTTACATTTCTGCATCCTAGACATTTCACTTGCATCACCCTAGTCCTGGCCCTGCTCTGG
ATCTTCCCAAATAAAGTTTTTGCCCTCAAGTTACATCCACTTCTTGGGGGGACTCAACCTAAAG
CAAATCCTATGGAGAAATTAGTCTCCCGTTTTATACATGGAAAACAATTTCAGAAAAGTAAAGA
GTTTTTATCACATAGCTGGTAAATGGGATGGGATTTGAATACAGGTCTGTTTTGACACCAGAAC
TTACACTGCCTGTACTGTCCTACATCTGACCTCCCACTTGACTCACACAGCCGATGACTCCATG
GAAATTTCAGGCTTGGTGGGCTCATTCTCACCTGTGGGGCAGGGCAGCTTTGGTGGAGAAGGGA
GGTAGAAAACGGACTGGAGGGTTGGTAGATGGGAAAATGTGGACACCCAAGTGGAAAGTGCCAT
ATGCACCAGCAAGGCAGGAAGTGGTTGTTTATTTCCTTCCCATTCTAAAAGCCCTGGACTGTTG
AGGTTATGGGAGGGCCCTCTTGTTTAATAAAAATTAGCTGATAGCTATTCTGTATCAGGTCTAG
AACCAGAACTTGAGGCTCCAAAGGTAAATAAGGAAAATTACCTGGGAGCCCATAGTGCAGTGGG
TAAAATGAACACATATATAGATGATTTTAATAAACTTGTAAATGCAAAGAAATTAGCAAAATCA
AGATAATAGGGAATGGGTGGGCAGGCTCCCAGCTGGGGTTAGGGCCAGGAGGAGCCTCTCAAGG
AAGAACTTCCCACCATTGCTGTCTGAACTGCAGTTTAACAGATGAGGGGAAATTAGGTGAAAAG
GTGTGAGAGTCCAAAGGGGGTGTCATTCTGGACAAATCGGCATGAACAAAGGCACAAAAGAAGT
AGCTTGATGCCTGTGGGAGAGTTGTAAGGTACATTCAGAGTATAAAGGGCATCCATACTGGGGA
GCCTATGAGGGCCTGTGTCCCTGGCTGCAGGCACTGAGGGTGGAGGGCAGTAAGCTCAGAGCAG
GGGGTGCCTAGCCTTTCAGCCCAGCAGCTGTACTCTATCCCTGTTCCGCAGTTACTTCTTGGTG
GTTAAGATTACACTAAGGGACTATGAGGGCAGCTTGTCTGGATTTGTCCTTCTCCTTGCTGGTC
AGTGACCATCTGGTATCTGCCCGAGTATTGCATCTGCTTTGCCTCTGCTACTGCCAGGGCTGTC
CCAGATGCTCACAGCATCCCTCTACTGACTGACCCAAAGACTTTCCTTGGCACTACAACTAGAG
ATCAGGACACCCACTGCCTGGTGAAATGAGCACGGCACTTTAAGAAACACTGGCAAGAGTTCTG
GTAATGCTTGTCATGTGTGTCCTTACCCTGGCTCAAGAGTGCAAATGTTAGGCCCTGGGTTTAA
TCTCCCAATACAGCAGGGGGAAGAGGTACAAATGCTGTTGTCAGCATAAATCACAGCTAGAGCT
TTTTGCATTCAACTAAACTAAGTTGAGAAATGGGAAGCTCAGGCTAGGAAGAATGCTGTTTTTG
TGGGTGACAGCCACTCTGCCTTCCCCAGTGCATCCTCCACTTCCATTGCCTTTCAGAGCCTGGT
TGGTACACAGTGTACTACAGCAGGGCTGATGTCTGCCATGCTTCCAGACCTAATTGTGTAAAAG
CTGATAGAAAAGTCACTGTCCCTGGTGTTCATCTAGTGTCATGTGGAAGCCTTGTCCTATATGG
TAGGGAACTGCTGATGAGGTAGTGGTAAAGTGTCCACCAATTTTCCTGAAACACAGATTGTTGC
AGTGTGCTTAGTCTCCTACAGTGGTGCCCCAGGGTTCTGTGCATTCAGGACTAGTTCAACGGAA
AAACAGCTTGGTGGCCAGCAGCCTTAGAAGCCTTAGACTTTGCTTCTCCTTCCAATAAAAAGAT
GCATGGTGTGAGCCTACTCTCCCCATTTAAGACAAAGGCTAGATTCCTCAGGCTGGCTGTCACC
TCTTCTCCCACCATATATCCCCTGTAGGCCCTGGGAGCTGCACACAGTTCCATGAAGGCACCTG
TGTGTATGTGACCTGTGATTGCAGGTATGCGCTCCTCTGTGAAAGGACCCCCTCTGCCAGCACA
CTGTTCTTTCTTCAAGACTTGGCTTCCACAGCCTGCCTAGCACTCATTCACTGTCAGTCCCTTC
CTCTTGTGTTTCTACATTGCCTCTTACCACATTTTTTAAAGCTGTTTGTTACACTGCATATTTC
CCAGGCTAAGCTCCCACTCCTTTCCAGGGATGTGCTACCACCTCAAAACTCCGAAGTGTTTATA
AAAGGAGCAGAATTTCTAGCATTGCAGTAGGGATGTCACAGGATCCTTGAGTCCATTCACAGTT
CCAGCATCCTGTGGTCATCTTACTTTACTTTACACCATAGCCCTAGCTACCCTAGGTTCCTCTT
AGAGCAAACTGGGAAGGAAGTTGACCTTCCTGAATTAGTGGATGTCTGGTAAGCAGTAGCTGAG
GGAAAGGGCGGGGCTTGGGGACATTATAACTTGGGTCACCCTGAGTTTCACTTTTGAACACAGA
CCAGGTCACTGTGTGCCTCACATTGAGAAAAGAGCTTAGCCCTGAGGAGGGTAATCAACTGCTA
TATCTCCCAGGTGACCCACTCCCATTGTGGAATCACATGGACTCCATTGGGCCTGCTGGGTTGC
AGCCTGGGGAAAGAGCCCTGGGCTGTCCCCAGGAGGGGTTACCCCTGCCCTCAGACAGCTCAGA
GCTGGTACAGGAATGTCTACAGCAATTCAAGGTGACAAGGACACAGCTGCAGCAGATCCAAGCC
AGCCTCCTGGATTCCATGGAGCAGGCATTGAAGGGACAGGCCAGCCCTGCTCCTGCTGTCCGGA
TGCTGCCCACATATGTGGGGTCTACCCCACATGGCACTGAACAAGGAGACTTTCTGGTGCTGGA
GCTAGGGGCCACAGGGGCCTCACTGCGAGTCTTGTGGGTGACTCTGACGGGCATCGAGGGGCAT
AGGGTGGAGCCCAGGAGCCAGGAGTTCATGATTCCTGAAGAGGTGGTACTGGGCACTGGCCAGC
AACTCTTTGACTTTGCCGCCTGCTGCTTGTCTGAGTTCCTGGATGCACACCCCGTGGGAAATCG
GGGCCTGCAGCTTGGGTTCAGCTTCTCCTTCCCTTGCCACCAAACAGGCCTGGACAAGAGCACC
CTCATTTCCTGGACTAAAGGTTTTAGGTGCAGCGGTGTAGAAGGCCAGGATGTGGTCCAGTTGC
TGAGAGATGCCATTCAGAGGCAGGGGGCCTACAGCATTGACGTGGTTGCTGTGGTGAACGACAC
AGTGGGCACCATGATGGGCTGTGAGCCAGGAACCCGTCCATGTGAGATTGGGCTCATCGTAGAC
ACTGGCACCAATGCATGTTACATGGAGGAGGCGAGGCATGTGGCCGTATTGGATGAGGACCGGG
GCCGCACCTGCGTCAGCATTGAATGGGGATCCTTCAACGATCATGGGGCCCTGGGGCCAGTGAT
GACCACCTTCGACCATGCCTTGGATCAGGAGTCCCTGAATCCTGGTGCCCAGAGGTTTGAAAAG
ATGATTGGGGGCTTATACCTGGGTGAGCTGGTGCGACTGGTGCTGGCCCACTTGGCCCGTCGTG
GCGTCCTCTTTGGTGGCTGTACCTCTCCTGCTTTGCTGAGCCAAGGCAGCATCCGTCTGGAGCA
TGTGGCTGAGATGGAGGACCCCTCCACTGGGGCAGCCCGTGTCTACACAATTCTGCAGGACCTG
GGTCTGAGCCTGGAGGCTTCAGATGCTGAGCTTGTGCAGCGTGTGTGCGCGGCCGTGTGCACGC
GGGCTGCCCAGCTTTGTGCGGCGGCCCTGGCTGCAGTCCTGTCCCGCCTGCAGCACAGCCGGGA
GCAGCAGACCCTCCAGGTTGCTGTGGCCACAGGAGGTCAAGTGTTTGAGCAGCACCTCAGGTTC
CACAGCATTTTGCAGGAGACAGTGATGCTCTTGGTCCCGGAATGTGATGTCTCCTTTATCCCCT
CTGTGGATGGAGGTGGCCGGGGTGTGGCAATGGTGACAGCTGTGGCTGCCCGCTTGGCTGCCCA
CCGGCGCCTGCTGGAGGAGACCCTGGCACCTTTCCGGTTGAACCTGGAGCAGCTGAAAGCCGTG
CAAGCGCAGATGCGGGAGGCCATGGCCAAGGGGCTCCGAGGGGAGGCTTCCTCTCTCCGTATGC
TACCCACTTACGTGCGAGCCACACCTGATGGCAGCGAGCGAGGAGACTTTCTGGCTTTGGACCT
GGGGGGCACCAACTTCCGGGTCCTCCTGGTGCGTTTGACAGAGGGAGGTGTGCAGATCATCAAC
CAGGTTTACTCCATCCCTGAGTGTGTGGCCCAGGGCTCTGGGCAGCAGCTCTTTGACCACATCG
TGGACTGCATCGTGGACTTCCAGCAGAGGCAGGGCATGAGTGGACAGAGCCTCCCCCTGGGTTT
CACTTTCTCCTTCCCATGCAAGCAGGTTGGCCTGGACCAGGGCATCCTTCTAAACTGGACTAAG
GGTTTCAATGCATCAGACTGTGAGGGCCATGATGTTGTGCATCTGCTGCGGGAAGCCATCAAAC
GCAGACAGGCAGTGGAGCTGAATGTTGTTGCCATTGTCAATGACACGGTGGGGACCATGATGTC
CTGTGGCTATGAGGATCCCCGTTGCGAGATAGGCCTCATTGTCGGAACTGGAACCAATGCCTGC
TACATGGAAGAGCTCCCAAATGTGGTGGACATGGCCGACGAGTCAGGCCAAATGTGCATCAACA
TGGAGTGGGGAGCCTTTGGGGATGATGGCTCACTGGGCATGCTCAGCACCTGCTTTGATGAGAG
TGTGGACCAGGCATCCATCAATCCTGGCAAGCAGAGATTTGAGAAGATGATCAGTGGTATGTAC
CTGGGGGAGATTGTCCGCCACATCCTCTTGCATTTGACCAGCCTTGGAGTTCTCTTCCGAGGCC
AGCAGACCCAGTGCCTTCAGACCAGGGACATCTTCAAGACCAAGTTTCTCTCTGAGATTGAAAG
CGACAGCCTGGCTCTGCGACAGGTCCGAGCCATCCTGGAGGATCTGGGGCTTCCCCTGACCTCA
GACGATGCCCTGATGGTCCTAGAGGTGTGCCAGGCTGTGTCCCGGAGAGCTGCTCAACTCTGTG
GGGCAGGTGTAGCTGCCGTGGTGGAGAAGATCCGGGAGAACCGTGGCCTGGAGGAATTGACAAT
CTCCGTGGGGGTGGATGGGACCCTCTACAAGCTGCATCCCCACTTCTCCAGCCTGGTAGCAGCC
ACAGTACGGGAACTGGCCCCTCGCTGTAAAGTCACTTTCCTGCAGTCAGAGGATGGATCTGGCA
AAGGTGCAGCTTTGGTCACTGCTGTTGCCTGTCGCCTTGCTCAGAAGACCCGTGTCTGAAGAAA
TCCACAGGAACCCTGGGATCTCAGCCCTAGTCTTGCCAGACCAGGGCCTGGACCTAGCCCGTCT
TCAAGCCAGACCAGCCACCAGGGACTCTCAGAATAGTCCATGTATGATACCTCTGTGGCCATCT
ACCCTCCCCGATAGCTTTTCCCAAGAGAGGTAGCACATGGGTTAGCAATATATATATATAATTT
ATTTACA

hide sequence

RefSeq Acc Id:

XM_040273104 ⟹ XP_040129038

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI

RefSeq Acc Id:

XM_040273105 ⟹ XP_040129039

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI

RefSeq Acc Id:

XM_040273106 ⟹ XP_040129040

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	122,097,741 - 122,118,657 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005333214	(Get FASTA)	NCBI Sequence Viewer
	XP_040129038	(Get FASTA)	NCBI Sequence Viewer
	XP_040129039	(Get FASTA)	NCBI Sequence Viewer
	XP_040129040	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000003653.3
GenBank Protein	KAG3265751	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005333214 ⟸ XM_005333157

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDSIGPAGLQPGERALGCPQEGLPLPSDSSELVQECLQQFKVTRTQLQQIQASLLDSMEQALKG
QASPAPAVRMLPTYVGSTPHGTEQGDFLVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFMIP
EEVVLGTGQQLFDFAACCLSEFLDAHPVGNRGLQLGFSFSFPCHQTGLDKSTLISWTKGFRCSG
VEGQDVVQLLRDAIQRQGAYSIDVVAVVNDTVGTMMGCEPGTRPCEIGLIVDTGTNACYMEEAR
HVAVLDEDRGRTCVSIEWGSFNDHGALGPVMTTFDHALDQESLNPGAQRFEKMIGGLYLGELVR
LVLAHLARRGVLFGGCTSPALLSQGSIRLEHVAEMEDPSTGAARVYTILQDLGLSLEASDAELV
QRVCAAVCTRAAQLCAAALAAVLSRLQHSREQQTLQVAVATGGQVFEQHLRFHSILQETVMLLV
PECDVSFIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNLEQLKAVQAQMREAMAKGL
RGEASSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRLTEGGVQIINQVYSIPECVAQG
SGQQLFDHIVDCIVDFQQRQGMSGQSLPLGFTFSFPCKQVGLDQGILLNWTKGFNASDCEGHDV
VHLLREAIKRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELPNVVDMA
DESGQMCINMEWGAFGDDGSLGMLSTCFDESVDQASINPGKQRFEKMISGMYLGEIVRHILLHL
TSLGVLFRGQQTQCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQA
VSRRAAQLCGAGVAAVVEKIRENRGLEELTISVGVDGTLYKLHPHFSSLVAATVRELAPRCKVT
FLQSEDGSGKGAALVTAVACRLAQKTRV

hide sequence

RefSeq Acc Id:	XP_040129040 ⟸ XM_040273106
- Peptide Label:	isoform X3
- UniProtKB:	I3M3J6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040129038 ⟸ XM_040273104
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040129039 ⟸ XM_040273105
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSSTOP00000003653 ⟸ ENSSTOT00000004073

Protein Domains

Hexokinase C-terminal Hexokinase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000004063	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000004073.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.40	UniProtKB/TrEMBL
	3.40.367.20	UniProtKB/TrEMBL
InterPro	ATPase_NBD	UniProtKB/TrEMBL
	Hexokinase	UniProtKB/TrEMBL
	Hexokinase_BS	UniProtKB/TrEMBL
	Hexokinase_C	UniProtKB/TrEMBL
	Hexokinase_N	UniProtKB/TrEMBL
NCBI Gene	Hk3	ENTREZGENE
PANTHER	HEXOKINASE-3	UniProtKB/TrEMBL
	PTHR19443	UniProtKB/TrEMBL
Pfam	Hexokinase_1	UniProtKB/TrEMBL
	Hexokinase_2	UniProtKB/TrEMBL
PRINTS	HEXOKINASE	UniProtKB/TrEMBL
PROSITE	HEXOKINASE_1	UniProtKB/TrEMBL
	HEXOKINASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53067	UniProtKB/TrEMBL
UniProt	I3M3J6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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